Browsing Department of Clinical Medicine by Issue Date
Now showing items 21-40 of 2077
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Functional and Prognostic Role of MicroRNAs in Cancer Associated Fibroblasts and Stroma in Oral Squamous Cell Carcinoma
(Doctoral thesis, 2023-11-23)Nyere studier har vist at forandringer i bindevevscellene som omgir kreftsvulsten er viktige for utviklingen av munnhulekreft. Kreft stroma kan regulere fenotypen av kreftcellene, og på den måten kan påvirke klinisk forløpet ... -
Cementing techniques for total knee arthroplasty in Norwegian hospitals; a questionnaire-based study
(Journal article; Peer reviewed, 2023-11-18)Background: Cementing technique in total knee arthroplasty (TKA) may influence implant survival. There is limited knowledge about the results with clinically used techniques. The aim of this study was to investigate ... -
An interdisciplinary intervention for children and adolescents with multiple referrals and complex health complaints: a feasibility study
(Journal article; Peer reviewed, 2023-11-11)Background: Children and adolescents with complex health complaints are often referred to several different healthcare specialists for assessments and treatment. This may result in fragmented care, higher risks of medical ... -
Effect of ADHD Medication on Criminality and Injuries : Quasi-Experimental Evidence for Patients on the Margin of Treatment
(Doctoral thesis, 2023-11-07)Attention-deficit/hyperactivity disorder (ADHD) er den vanligste nevropsykiatriske lidelsen hos barn og unge. Store geografiske variasjoner i diagnostisering og medisinering av ADHD har bidratt til bekymringer om under- ... -
Orthopaedic surgeons' ability to detect pathologic hip fractures: review of 1484 fractures reported to the Norwegian Hip Fracture Register
(Journal article; Peer reviewed, 2023-11-04)Background: The proximal femur is the most common location of metastases in the appendicular skeleton. Data on pathologic hip fractures, however, are sparse despite it is the most frequently operated pathologic fracture. ... -
Syndromic molecular testing in adults hospitalized for suspected community-acquired pneumonia
(Doctoral thesis, 2023-10-26)Den mikrobielle etiologien hos pasienter med samfunnservervet lungebetennelse (CAP) blir ofte ikke avklart på grunn av utilstrekkelige mikrobiologiske metoder og vanskeligheter med å skaffe prøver fra nedre luftveier. Rask ... -
Specific neuropsychiatric symptoms are associated with functional decline trajectories in Alzheimer’s disease and Lewy body dementia: a five-year follow-up study
(Journal article; Peer reviewed, 2023-10-17)Background: Neuropsychiatric symptoms (NPS) are often overlooked and under-identified symptoms associated with dementia, despite their significant impact on the prognosis of individuals living with the disease. The specific ... -
Case Report: Limbic encephalitis following treatment with durvalumab for small-cell lung cancer
(Journal article; Peer reviewed, 2023-10-16)Background: Durvalumab is an immune checkpoint Inhibitor (ICIs) that is used in the treatment of malignant tumors, such as lung cancer and melanoma. ICIs are associated with immune-related adverse events including autoimmune ... -
Polyvinylpyrrolidone deposition disease : The role of pathology in understanding disease and death in persons with opioid addiction and intravenous drug use
(Doctoral thesis, 2023-10-13)Bakgrunn og målsetting: Polymeren polyvinylpyrrolidon (PVP) er mye brukt som tilsetningsstoff i legemidler. PVP med høy molekylvekt kan ikke utskilles via nyrene og vil derfor opphopes i kroppens vev dersom det administreres ... -
Case report: Seropositive myasthenia gravis complicated by limbic encephalitis positive for antibodies to AMPAR and Lgi1
(Journal article; Peer reviewed, 2023-10-12)Objectives: Autoantibodies to the α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor (AMPAR) and leucine-rich glioma-inactivated 1 (Lgi1) are associated with autoimmune encephalitis. We described an acetylcholine ... -
Intramedullary nails in the treatment of trochanteric and subtrochanteric fractures
(Doctoral thesis, 2023-09-15)Et hoftebrudd er en alvorlig og potensielt dødelig hendelse for et eldre, skrøpelig individer. Et slikt brudd fører svært ofte til økt hjelpebehov, varig nedsatt funksjon og ovedødelighet. Valg av implantat i behandlingen ... -
Neurotrauma care in Ethiopia: Building for the future
(Doctoral thesis, 2023-08-25)Bakgrunn: Nevrotraumer er et stort folkehelseproblem i Etiopia, og hovedmålet med denne oppgaven var å studere behandlingen av nevrotraumepasienter i landet. Materiale og metoder: Vi brukte prospektive (artikkel I, II og ... -
Long-Term Use of Amoxicillin Is Associated with Changes in Gene Expression and DNA Methylation in Patients with Low Back Pain and Modic Changes
(Journal article; Peer reviewed, 2023-07-21)Long-term antibiotics are prescribed for a variety of medical conditions, recently including low back pain with Modic changes. The molecular impact of such treatment is unknown. We conducted longitudinal transcriptome and ... -
The TP53 Codon 72 Arginine Polymorphism Is Found with Increased TP53 Somatic Mutations in HPV(−) and in an Increased Percentage among HPV(+) Norwegian HNSCC Patients
(Journal article; Peer reviewed, 2023-06-26)Background: Somatic TP53 mutations are frequent in head and neck squamous cell carcinoma (HNSCC) and are important pathogenic factors. Objective: To study TP53 mutations relative to the presence of human papillomavirus ... -
Whole blood in prehospital damage control resuscitation : -Safety, feasibility, and logistics
(Doctoral thesis, 2023-06-14)Bakgrunn De siste tiårene har det vært et paradigmeskifte i behandlingen av blødningsjokk. Skadebegrensende resuscitering har som hensikt å understøtte hemostatisk evne hos pasienten og reversere og dempe konsekvensene ... -
Not every estimate counts – evaluation of cell composition estimation approaches in brain bulk tissue data
(Journal article; Peer reviewed, 2023-06-07)Background: Variation in cell composition can dramatically impact analyses in bulk tissue samples. A commonly employed approach to mitigate this issue is to adjust statistical models using estimates of cell abundance derived ... -
Matvaner og oppfatninger om kosthold hos unge mannlige tømrere
(Master thesis, 2023-06-05)Det er gjort lite kostholdsdata på enkeltgrupper i Norge. Denne oppgaven tar utgangspunkt i det den ser som et kunnskapshull i ernæringsfeltet: kunnskap om erfaringer, holdninger, oppfatninger og meninger som former ... -
Dietary Macroalgae: Content of Iodine and Heavy Metals and Metalloids and Status Among Consumers in Bergen and Oslo
(Master thesis, 2023-05-30)Bakgrunn: Det er få gode kilder til jod i kostholdet vårt, og siden disse i tillegg ikke blir spist regelmessig i tilstrekkelige mengder, har mange for lavt inntak av jod. I makroalger er det funnet høye nivåer av jod. ... -
The ANeED study – ambroxol in new and early dementia with Lewy bodies (DLB): protocol for a phase IIa multicentre, randomised, double-blinded and placebo-controlled trial
(Journal article; Peer reviewed, 2023-05-26)Background: Currently, there are no disease-modifying pharmacological treatment options for dementia with Lewy bodies (DLB). The hallmark of DLB is pathological alpha-synuclein (aS) deposition. There are growing amounts ... -
Different Dietary Ratios of Camelina Oil to Sandeel Oil Influence the Capacity to Synthesise and Deposit EPA and DHA in Zucker Fa/Fa Rats
(Journal article; Peer reviewed, 2023-05-17)Plant-based food provides more ALA (α-linolenic acid) and less EPA (eicosapentaenoic acid) and DHA (docosahexanoic acid) than marine food. Earlier studies indicate that cetoleic acid (22:1n-11) stimulates the n-3 pathway ...