Browsing Department of Chemistry by Author "Eikemo, Vebjørn"
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Photodegradable antimicrobial agents - synthesis, photodegradation, and biological evaluation
Eikemo, Vebjørn; Sydnes, Leiv K.; Sydnes, Magne Olav (Journal article; Peer reviewed, 2021)Multi-drug resistant (MDR) bacteria are already a significant health-care problem and are making the combat of infections quite challenging. Here we report the synthesis of several new compounds containing an ethanolamine ... -
Photodegradable Antimicrobial Agents: Synthesis and Mechanism of Degradation
Eikemo, Vebjørn; Holmelid, Bjarte; Sydnes, Leiv K.; Sydnes, Magne Olav (Journal article; Peer reviewed, 2022)As a strategy to inactivate antimicrobial agents after use, we designed a range of ethanolamine derivatives where four of them possessed interesting activity. The ethanolamine moiety facilitates photodecomposition, which ...