Browsing Faculty of Medicine by Title
Now showing items 1733-1752 of 8886
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Cross-cultural Validation of the Norwegian Version of the Banff Patellofemoral Instability Instrument 2.0
(Journal article; Peer reviewed, 2023)Background: The Banff Patellofemoral Instability Instrument (BPII) 2.0 is a disease-specific quality of life questionnaire for patients with patellofemoral instability. While good psychometric properties have been demonstrated, ... -
Cross-fitted instrument: A blueprint for one-sample Mendelian randomization
(Journal article; Peer reviewed, 2022-08-29)Bias from weak instruments may undermine the ability to estimate causal effects in instrumental variable regression (IVR). We present here a new approach to handling weak instrument bias through the application of a new ... -
Cross-reactivity of the CEDIA buprenorphine assay in drugs-of-abuse screening: influence of dose and metabolites of opioids
(Peer reviewed; Journal article, 2015-10-28)Purpose: The cloned enzyme donor immunoassay (CEDIA) for buprenorphine is applied for both urine drugs-of-abuse screening and compliance monitoring. Sensitivity, specificity, and optimal cutoff of this assay have differed ... -
A cross-sectional analysis of the association between health related quality of life and bodyweight changes
(Master thesis, 2013-01-05)Introduction Bodyweight outside the normal range is commonly associated with reduced health related quality of life (HRQL), while physical activity has shown to improve HRQL. Few studies have investigated the effect of ... -
A cross-sectional study of health literacy in patients with chronic kidney disease: Associations with demographic and clinical variables
(Peer reviewed; Journal article, 2019-07-26)Aim The aim of this study was to investigate health literacy in patients with chronic kidney disease in a multidimensional perspective. Design A descriptive, cross‐sectional study. Methods Patients with chronic kidney ... -
A cross-sectional study of self-reported general health, lifestyle factors, and disease: the Hordaland Health Study
(Peer reviewed; Journal article, 2014-10-02)Background. Information on self-reported health is important for health professionals, and the aim of this study was to examine associations between lifestyle factors and self-reported health and the mediating effect of ... -
Cross-sectional study on exhaled nitric oxide in relation to upper airway inflammatory disorders with regard to asthma and perennial sensitization
(Journal article; Peer reviewed, 2022)Background: Fractional exhaled nitric oxide (FeNO) is a well-known marker of type-2 inflammation. FeNO is elevated in asthma and allergic rhinitis, with IgE sensitization as a major determinant. Objective: We aimed to ... -
A cross-sectional study on the nutritional status, dietary diversity, and small fish consumption patterns in coastal fishing communities of Ghana
(Journal article; Peer reviewed, 2023)Fish is readily available to fishing communities. Given the high nutritional value of fish, these communities are expected to have better nutritional status, compared to non-fishing communities. However, this assumption ... -
Cross-Species Functional Genomic Analysis Identifies Resistance Genes of the Histone Deacetylase Inhibitor Valproic Acid
(Peer reviewed; Journal article, 2012-11-14)The mechanisms of successful epigenetic reprogramming in cancer are not well characterized as they involve coordinated removal of repressive marks and deposition of activating marks by a large number of histone and DNA ... -
A cross-species whole genome siRNA screen in suspension-cultured Chinese hamster ovary cells identifies novel engineering targets
(Peer reviewed; Journal article, 2019-06-18)High-throughput siRNA screens were only recently applied to cell factories to identify novel engineering targets which are able to boost cells towards desired phenotypes. While siRNA libraries exist for model organisms ... -
Cross-trait genome-wide association analysis of C-reactive protein level and psychiatric disorders
(Journal article; Peer reviewed, 2023)C-reactive protein (CRP) tends to be elevated in individuals with psychiatric disorders. Recent findings have suggested a protective effect of the genetic liability to elevated CRP on schizophrenia risk and a causative ... -
Crosstalk between HSF1 and HSF2 during the heat shock response in mouse testes
(Peer reviewed; Journal article, 2014-12)Heat Shock Factor 1 (HSF1) is the primary transcription factor responsible for the response to cellularstress, while HSF2 becomes activated during development and differentiation, including spermatogen-esis. Although both ... -
Crowdsourcing in proteomics: public resources lead to better experiments
(Peer reviewed; Journal article, 2013-04)With the growing interest in the field of proteomics, the amount of publicly available proteome resources has also increased dramatically. This means that there are many useful resources available for almost all aspects ... -
Crucial aspects promoting meaning and purpose in life: perceptions of nursing home residents
(Peer reviewed; Journal article, 2017-10-30)Background: Meaning and purpose in life are fundamental to human beings. In changing times, with an aging population and increased life expectancy, the need for health care services and long-term care is likely to grow. ... -
Cryo-EM, X-ray diffraction, and atomistic simulations reveal determinants for the formation of a supramolecular myelin-like proteolipid lattice
(Journal article; Peer reviewed, 2020)Myelin protein P2 is a peripheral membrane protein of the fatty acid–binding protein family that functions in the formation and maintenance of the peripheral nerve myelin sheath. Several P2 gene mutations cause human ... -
Cryoballoon vs. radiofrequency catheter ablation: insights from NOrwegian randomized study of PERSistent Atrial Fibrillation (NO-PERSAF study)
(Journal article; Peer reviewed, 2022)Aims Pulmonary vein isolation (PVI) is still regarded as a cornerstone for treatment of persistent atrial fibrillation (AF). This study evaluated the effectiveness of PVI performed with cryoballoon ablation (CBA) in ... -
Cryoneurolysis for cervicogenic headache - A double blinded randomized controlled study
(Journal article; Peer reviewed, 2020)Background and aims: Cervicogenic headache (CEH) is a debilitating condition and analgesics have limited effect. Percutaneous cryoneurolysis is thus still in use although the clinical evidence is lacking. We present a ... -
Cryptosporidiosis in low-resource healthcare settings : Near-patient diagnostics, risk factors, and parasite shedding dynamics in young Ethiopian children
(Doctoral thesis, 2023-04-28)Bakgrunn: Tarmparasitten Cryptosporidium er en ledende årsak til diaré og dødsfall hos småbarn i lavinntektsland. Målretta behandling trengs, men forutsetter presise diagnostiske tester som er egna for ressursfattige ... -
Cryptosporidium Infections in Africa—How Important Is Zoonotic Transmission? A Review of the Evidence
(Journal article; Peer reviewed, 2020)Cryptosporidium, a protozoan parasite in the phylum Apicomplexa, is the etiological agent of cryptosporidiosis, an intestinal infection characterized by profuse watery diarrhea. Over 30 species of Cryptosporidium are ... -
Crystal and solution structure of NDRG1, a membranebinding protein linked to myelination and tumour suppression
(Journal article; Peer reviewed, 2021)N-myc downstream-regulated gene 1 (NDRG1) is a tumour suppressor involved in vesicular trafficking and stress response. NDRG1 participates in peripheral nerve myelination, and mutations in the NDRG1 gene lead to ...