Browsing Faculty of Medicine by Title
Now showing items 1913-1932 of 8886
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Depression in Persons with Diabetes by Ageand Antidiabetic Treatment: A Cross-Sectional Analysis with Data from the Hordaland Health Study.
(Peer reviewed; Journal article, 2015-05-26)Background: Persons with diabetes have increased risk of depression, however, studies addressing whether the risk varies by age and type of antidiabetic treatment have yielded conflicting results. The aim of this study was ... -
Depression trajectories and cytokines in schizophrenia spectrum disorders - A longitudinal observational study
(Journal article; Peer reviewed, 2023)Depression occurs frequently in all phases of schizophrenia spectrum disorders. Altered activity in the immune system is seen in both depression and schizophrenia. We aimed to uncover depressive trajectories in a sample ... -
Depressive symptoms in psychotic disorders : Trajectories of depression and antidepressive effectiveness of antipsychotic medication
(Doctoral thesis, 2020-10-16)Background: Depressive symptoms are common in psychotic disorders and contribute to impaired functioning, a poorer quality of life, elevated relapse rate and suicide risk. Depression in schizophrenia may emerge as part of ... -
Derivation and Molecular Characterization of a Morphological Subpopulation of Human iPSC Astrocytes Reveal a Potential Role in Schizophrenia and Clozapine Response
(Journal article; Peer reviewed, 2021)Astrocytes are the most abundant cell type in the human brain and are important regulators of several critical cellular functions, including synaptic transmission. Although astrocytes are known to play a central role in ... -
Describing the status of reproductive ageing simply and precisely: A reproductive ageing score based on three questions and validated with hormone levels
(Journal article; Peer reviewed, 2020)Objective Most women live to experience menopause and will spend 4–8 years transitioning from fertile age to full menstrual stop. Biologically, reproductive ageing is a continuous process, but by convention, it is defined ... -
Description of dietary patterns and food diversity in a selected sample of Maya women: a pilot field study in the Lake Atlitlán area, Guatemala
(Master thesis, 2023-05-16)Background Indigenous communities in Guatemala predominantly live in rural and difficult-to-reach areas. These communities have been historically discriminated, leading to a deficient social and political representation, ... -
Design and challenges of a large HIV prevention clinical study on mother-to-child transmission: ANRS 12397 PROMISE-EPI study in Zambia and Burkina Faso
(Journal article; Peer reviewed, 2021)Post-natal HIV infection through breastfeeding remains a challenge in many low and middle-income countries, particularly due to non-availability of alternative infant feeding options and the suboptimal Prevention of Mother ... -
Design efficiency in genetic association studies
(Journal article; Peer reviewed, 2020)Selecting the best design for genetic association studies requires careful deliberation; different study designs can be used to scan for different genetic effects, and each design has its own set of strengths and limitations. ... -
Design of the study: How can health care help female breast cancer patients reduce their stress symptoms? A randomized intervention study with stepped-care
(Peer reviewed; Journal article, 2012-05-04)Background: A life threatening illness such as breast cancer can lead to a secondary diagnosis of PTSD (post traumatic stress disorder) with intrusive thoughts and avoidance as major symptoms. In a former study by the ... -
Design of tumor-specific immunotherapies using dendritic cells - effect of bromelain on dendritic cell maturation
(Master thesis, 2009-06-02)Immunotherapy using dendritic cells (DC) has shown promising results in clinical trials, but few relevant successes are recorded. Therefore, the choice of an appropriate DC population is critical for the outcome of this ... -
Design of tumour-specific immunotherapies using dendritic cells – analyses of IL15-DC
(Master thesis, 2009-05-31)Immunotherapy of malignancies aims at activating the patient’s own immune system to fight the tumour affecting the patient. Even though the use of dendritic cells (DC) has shown promising results, the DC vaccination strategy ... -
Designing usable mobile forms for collection of health data in Uganda
(Doctoral thesis, 2020-03-03)Background: Data collection entails obtaining quality and useful information by different organizations and institutions for purposes of answering a research question, establishing facts, making better decisions and solving ... -
Despite symptom severity, do nursing home residents experience joy-of-life? The associations between joy-of-life and symptom severity in Norwegian nursing home residents
(Journal article; Peer reviewed, 2021)Background: Finding new approaches to increase health and well-being among nursing home (NH) residents is highly warranted. From a holistic perspective, several Norwegian municipalities have implemented the certification ... -
“Det sitter i veggene”. Materialitet og mennesker i distriktspsykiatriske sentra
(Doctoral thesis, 2009-02-27)This dissertation examines the impact that the materiality of institutions has on patients and staff. Fieldwork has been carried out at five district psychiatric centres (Distriktspsykiatriske sentra, DPS) that were ... -
Det som sitter i veggene
(Peer reviewed; Journal article, 2013)Rommet ser ut til spille en viktig rolle når man informerer om helse. Et forskningsprosjekt i samarbeid mellom Høgskolene Sør-Trøndelag, Molde og Volda har invitert en gruppe pårørende til mennesker med demens til ... -
Detailed stratified GWAS analysis for severe COVID-19 in four European populations
(Journal article; Peer reviewed, 2022)Given the highly variable clinical phenotype of Coronavirus disease 2019 (COVID-19), a deeper analysis of the host genetic contribution to severe COVID-19 is important to improve our understanding of underlying disease ... -
Detecting diferentially methylated regions using a fast wavelet‑based approach to functional association analysis
(Journal article; Peer reviewed, 2021)Background We present here a computational shortcut to improve a powerful wavelet-based method by Shim and Stephens (Ann Appl Stat 9(2):665–686, 2015. https://doi.org/10.1214/14-AOAS776) called WaveQTL that was originally ... -
Detection and molecular characterization of herpes simplex virus from Tanzania and Norway
(Doctoral thesis, 2006-12-22) -
Detection and significance of small and low proliferation breast cancer
(Journal article; Peer reviewed, 2022)Objectives To determine the frequency and discuss possible implications of early breast cancer with particularly good prognosis and defined by tumor diameter and cell proliferation. Setting Detection of small and ... -
Detection of a broad range of Leishmania species and determination of parasite load of infected mouse by real-time PCR targeting the arginine permease gene AAP3
(Peer reviewed; Journal article, 2014-09)Leishmaniasis is one of the world's most neglected infectious diseases, affecting around 12 million people and more than 350 million at risk of infection. The clinical picture varies from self-healing cutaneous lesions to ...