Browsing Faculty of Medicine by Title
Now showing items 4039-4058 of 8871
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Hydroxyurea synergizes with valproic acid in wild-type p53 acute myeloid leukaemia
(Peer reviewed; Journal article, 2016)Palliative care in acute myeloid leukaemia (AML) is inadequate. For elderly patients, unfit for intensive chemotherapy, median survival is 2–3 months. As such, there is urgent demand for low-toxic palliative alternatives. ... -
HYPERAKTIV: An Activity Dataset from Patients with Attention-Deficit/Hyperactivity Disorder (ADHD)
(Chapter, 2021)Machine learning research within healthcare frequently lacks the public data needed to be fully reproducible and comparable. Datasets are often restricted due to privacy concerns and legal requirements that come with ... -
Hyperbaric oxygen therapy and cancer—a review
(Peer reviewed; Journal article, 2012-10-02)Hypoxia is a critical hallmark of solid tumors and involves enhanced cell survival, angiogenesis, glycolytic metabolism, and metastasis. Hyperbaric oxygen (HBO) treatment has for centuries been used to improve or cure ... -
Hyperferritinemi-katarakt-syndrom
(Journal article; Peer reviewed, 2020) -
Hyperferritinemia—a clinical overview
(Journal article; Peer reviewed, 2021)Ferritin is one of the most frequently requested laboratory tests in primary and secondary care, and levels often deviate from reference ranges. Serving as an indirect marker for total body iron stores, low ferritin is ... -
Hyperglycemia a risk factor for lower extremity muscle- tendon pathology? A prospective cohort study.
(Master thesis, 2019-06-19) -
Hyperglycemia in pregnancy. : Diagnostics, biomarkers, follow-up, and monitoring of glycemic control
(Doctoral thesis, 2023-02-24)Diabetes mellitus er blant de største globale folkehelseutfordringene i vår tid. Hyperglykemi affiserer ett av seks svangerskap og svangerskapsdiabetes (SVD) er den vanligste årsak. Gravide med hyperglykemi har økt risiko ... -
Hyperoxia increases the uptake of 5-fluorouracil in mammary tumors independently of changes in interstitial fluid pressure and tumor stroma
(Peer reviewed; Journal article, 2009-12-17)Background: Hypoxia is associated with increased resistance to chemo- and radiation-therapy. Hyperoxic treatment (hyperbaric oxygen) has previously been shown to potentiate the effect of some forms of chemotherapy, and ... -
Hyperoxia retards growth and induces apoptosis and loss of glands and blood vessels in DMBA-induced rat mammary tumors
(Journal article, 2007-01-30)This study investigated the effects of hyperoxic treatment on growth, angiogenesis, apoptosis, general morphology and gene expression in DMBA-induced rat mammary tumors. Methods: One group of animals was exposed to normobaric ... -
Hyperoxic Treatment Induces Mesenchymal-to-Epithelial Transition in a Rat Adenocarcinoma Model
(Peer reviewed; Journal article, 2009-07-28)Tumor hypoxia is relevant for tumor growth, metabolism and epithelial-to-mesenchymal transition (EMT). We report that hyperbaric oxygen (HBO) treatment induced mesenchymal-to-epithelial transition (MET) in a dimetyl-a-be ... -
Hyperpolarised 13C-MRI identifies the emergence of a glycolytic cell population within intermediaterisk human prostate cancer
(Journal article; Peer reviewed, 2022)Hyperpolarised magnetic resonance imaging (HP 13C-MRI) is an emerging clinical technique to detect [1-13C]lactate production in prostate cancer (PCa) following intravenous injection of hyperpolarised [1-13C]pyruvate. Here ... -
Hypersementose og endodontiske implikasjoner
(Journal article; Peer reviewed, 2022)Hypersementose er forbundet med lokale og systemiske faktorer, men etiologien er ikke godt kartlagt. Vanskeligheter med å bedømme røntgenologisk tykkelse på sementlaget ved hypersementose, vil direkte kunne påvirke beslutning ... -
Hypertension in women: Should there be a sex-specific threshold?
(Journal article; Peer reviewed, 2021)Conventionally, hypertension is defined by the same blood pressure (BP) threshold (systolic BP ≥140 and/or diastolic BP ≥90 mmHg) in both women and men. Several studies have documented that women with hypertension are more ... -
Hypertensive nephrosclerosis: wider kidney biopsy indications may be needed to improve diagnostics
(Journal article; Peer reviewed, 2020-07-02)Background Hypertensive nephrosclerosis is the presumed underlying cause in many end‐stage kidney disease (ESKD) patients, but the diagnosis is disputed and based on clinical criteria with low diagnostic accuracy. Ob ... -
Hypertensive pregnancy disorders increase the risk of maternal cardiovascular disease after adjustment for cardiovascular risk factors
(Peer reviewed; Journal article, 2019)Background and aim: Hypertensive pregnancy disorders are associated with subsequent cardiovascular disease (CVD), but the extent to which this association is explained by shared risk factors is unknown. We aimed to evaluate ... -
The hypertriglyceridemic-waist phenotype is associated with the Framingham risk score and subclinical atherosclerosis in Canadian Cree
(Peer reviewed; Journal article, 2015-11)Background and aims: For primary prevention of cardiovascular disease (CVD), Canadian guidelines recommend that asymptomatic Canadians with abdominal obesity undergo Framingham risk score (FRS) assessment, and that in ... -
Hypertrofi ved styrketrening: hvilket volum gir størst effekt? En litteraturstudie
(Master thesis, 2022-11-19)Sammendrag -
Hypoglycemia and decreased insulin requirement caused by malignant insulinoma in a type 1 diabetic patient: when the hoof beats are from a zebra, not a horse
(Peer reviewed; Journal article, 2017-06)Insulinomas are uncommon tumors, and in patients with diabetes mellitus they are extremely rare. We describe a patient with type 1 diabetes who developed malignant insulinoma. When hypoglycemic episodes persist in a patient ... -
Hypomagnesemia and functional hypoparathyroidism due to novel mutations in the Mg-channel TRPM6
(Peer reviewed; Journal article, 2015)Primary hypomagnesemia with secondary hypocalcemia (HSH) is an autosomal recessive disorder characterized by neuromuscular symptoms in infancy due to extremely low levels of serum magnesium and moderate to severe hypocalcemia. ... -
Hypoxia and hypotension in patients intubated by physician staffed helicopter emergency medical services - a prospective observational multi-centre study
(Peer reviewed; Journal article, 2017-07-11)Background: The effective treatment of airway compromise in trauma and non-trauma patients is important. Hypoxia and hypotension are predictors of negative patient outcomes and increased mortality, and may be important ...