Browsing Faculty of Medicine by Title
Now showing items 4575-4594 of 8845
-
Interaction between ingested nutrients and gut endocrine cells in patients with irritable bowel syndrome (Review)
(Peer reviewed; Journal article, 2014-08)Several endocrine cell abnormalities have been reported in different segments of the gastrointestinal tract of patients with irritable bowel syndrome (IBS). These cells have specialized microvilli that project into the ... -
Interaction of leisure-time physical activity with body mass index on the risk of obesity-related cancers: A pooled study
(Journal article; Peer reviewed, 2022)Physical activity (PA) has been associated with a lower risk of some obesity-related cancers, but the combined association and interaction of PA and body weight on obesity-related cancer risk is less clear. We examined the ... -
Interactions between endothelial and bone marrow stromal cells of relevance to bone tissue engineering
(Doctoral thesis, 2011-02-04)Much research effort is being directed towards the development of bone tissue engineering techniques as alternatives to grafts for the treatment of bone defects. A major challenge is that following implantation of the ... -
Interactions between Fusobacterium nucleatum and Primary Human Oral Cells: In Vitro Studies in Monolayer and Organotypic Culture Models
(Doctoral thesis, 2012-06-21)F. nucleatum is a Gram-negative bacterium, member of normal flora in the oral cavity, which has a major role in the formation of the subgingival biofilm. The adhesins expressed on the cell wall outer membrane confer F. ... -
Interactions between the Helicopter Emergency Medical Service (HEMS) and Primary Emergency Health Care in Norway
(Doctoral thesis, 2023-03-08)Norge har et prehospitalt system som inkluderer legevaktleger i vakt døgnet rundt. Sammen med bilambulansetjenesten utgjør legevakttjenesten ryggraden i den prehospitale beredskapen. Luftambulansetjenesten med anestesileger ... -
The interactive relationship between pain, psychosis, and agitation in people with dementia: results from a cluster-randomised clinical trial
(Peer reviewed; Journal article, 2016-03)Background. Neuropsychiatric symptoms are common in people with dementia, and pain is thought to be an important underlying factor. Pain has previously been associated with agitation, and pain treatment has been shown to ... -
Interdisciplinary Approaches Suggested for Children With Multiple Hospital Referrals Presenting With Non-specific Conditions
(Journal article; Peer reviewed, 2021)Aims: To describe the care patterns of patients with repeated referrals to both mental and somatic specialist healthcare, and to study their diagnostic processes. Methods: In a previous register study patients aged 6–12 ... -
An interdisciplinary intervention for children and adolescents with multiple referrals and complex health complaints: a feasibility study
(Journal article; Peer reviewed, 2023-11-11)Background: Children and adolescents with complex health complaints are often referred to several different healthcare specialists for assessments and treatment. This may result in fragmented care, higher risks of medical ... -
An interdisciplinary intervention for children with complex health complaints; a feasibility study of selection criteria
(Journal article; Peer reviewed, 2023)Background: There is a need for re-designing the health service for children suffering from complex and compound health complaints. Based on a previous register study, we have developed criteria to select patients with ... -
Interfering with long non-coding RNA MIR22HG processing inhibits glioblastoma progression through suppression of Wnt/β-catenin signalling
(Peer reviewed; Journal article, 2020)Long non-coding RNAs play critical roles in tumour progression. Through analysis of publicly available genomic datasets, we found that MIR22HG, the host gene of microRNAs miR-22-3p and miR-22-5p, is ranked among the most ... -
Interferon (IFN)-γ-mediated inflammation and the kynurenine pathway in relation to bone mineral density: the Hordaland Health Study
(Peer reviewed; Journal article, 2014-04-24)The risk of osteoporosis increases in inflammatory disorders. In cell-mediated immune activation, interferon (IFN)-γ stimulates macrophage release of neopterin and increases the activity of indoleamine 2,3-dioxygenase ... -
Interferon gamma (IFN-γ)-mediated inflammation and the kynurenine pathway in relation to risk of hip fractures: The Hordaland Health Study
(Peer reviewed; Journal article, 2014-05-10)Summary The cytokine interferon gamma (IFN-γ) stimulates neopterin release and tryptophan degradation into kynurenines through the kynurenine pathway. High levels of neopterin were associated with increased hip fracture ... -
Interferon-γ–induced inflammatory markers and the risk of cancer: The Hordaland Health Study
(Peer reviewed; Journal article, 2014-06-19)Background It has been reported that interferon-γ (IFN-γ)–induced inflammatory markers, such as circulating neopterin and kynurenine-to-tryptophan ratio (KTR), are increased in patients with cancer and are also a predictor ... -
Interictal epileptiform discharges vary across age groups
(Journal article; Peer reviewed, 2020-01)Objective: To investigate whether the occurrence and morphology of interictal epileptiform discharges (IEDs) in scalp-EEG change by age. Methods: 10,547 patients who had a standard or sleep deprived EEG recording reported ... -
Interleukin-1 Inhibition and Fatigue in Primary Sjögren's Syndrome – A Double Blind, Randomised Clinical Trial
(Peer reviewed; Journal article, 2012)Objectives Fatigue is a major cause of disability in primary Sjögren's syndrome (pSS). Fatigue has similarities with sickness behaviour in animals; the latter mediated by pro-inflammatory cytokines, in particular interleukin ... -
Interleukin-1-related activity and hypocretin-1 in cerebrospinal fluid contribute to fatigue in primary Sjögren’s syndrome
(Journal article; Peer reviewed, 2019)Background Fatigue is a common and sometimes debilitating phenomenon in primary Sjögren’s syndrome (pSS) and other chronic inflammatory diseases. We aimed to investigate how IL-1 β-related molecules and the neuropeptide ... -
Interleukin-18 signaling system links to agitation in severe mental disorders
(Journal article; Peer reviewed, 2022)Objective Agitation is a challenging clinical feature in severe mental disorders, but its biological correlates are largely unknown. Inflammasome-related abnormalities have been linked to severe mental disorders and ... -
Interleukin-2 receptor in the pathogenesis of diabetic complications and Sjögren's syndrome
(Doctoral thesis, 2021-12-14)The cytokine interleukin-2 (IL-2) acts as a double-edged sword by promoting both immunity and immune tolerance. Regulatory T cells (Tregs) are responsible for maintaining self-tolerance and constitutively express the high ... -
Interleukin-6 in allogeneic stem cell transplantation: Its possible importance for immunoregulation and as a therapeutic target
(Peer reviewed; Journal article, 2017-06-08)Allogeneic stem cell transplantation is associated with a high risk of treatment-related mortality mainly caused by infections and graft-versus-host disease (GVHD). GVHD is characterized by severe immune dysregulation and ... -
Intermediate care in nursing home after hospital admission: a randomized controlled trial with one year follow-up
(Peer reviewed; Journal article, 2014-12-09)Background: Intermediate care is intended to reduce hospital admissions and facilitate early discharge. In Norway, a model was developed with transfer to intermediate care shortly after hospital admission. Efficacy and ...