Browsing Faculty of Medicine by Title

Now showing items 6168-6187 of 8878

    • Paternal and maternal obesity but not gestational weight gain is associated with type 1 diabetes 

      Magnus, Maria Christine; Olsen, Sjurdur Frodi; Granström, Charlotta; Lund-Blix, Nicolai Andre; Svensson, Jannet; Johannesen, Jesper; Fraser, Abigail; Skrivarhaug, Torild; Joner, Geir; Njølstad, Pål Rasmus; Størdal, Ketil; Stene, Lars Christian Mørch (Peer reviewed; Journal article, 2018-04)
      Background Our objective was to examine the associations of parental body mass index (BMI) and maternal gestational weight gain with childhood-onset type 1 diabetes. Comparing the associations of maternal and paternal BMI ...

    • Paternal characteristics associated with maternal periconceptional use of folic acid supplementation 

      Mortensen, Jan Helge Seglem; Øyen, Nina; Nilsen, Roy Miodini; Fomina, Tatiana; Tretli, Steinar; Bjørge, Tone (Peer reviewed; Journal article, 2018-05-30)
      Background: Maternal predictors of folic acid (FA) supplementation use to reduce offspring risk of neural tube defects are well known, while paternal determinants for maternal FA use are less known. Such knowledge is ...

    • Paternal country of origin and adverse neonatal outcomes in births to foreign-born women in Norway: A population-based cohort study 

      Vik, Eline Skirnisdottir; Aasheim, Vigdis; Nilsen, Roy Miodini; Small, Rhonda; Moster, Dag; Schytt, Erica (Journal article; Peer reviewed, 2020)
      Background Migration is a risk factor for adverse neonatal outcomes. The various impacts of maternal origin have been reported previously. The aim of this study was to investigate associations between paternal origin and ...

    • Pathogenic Carboxyl Ester Lipase (CEL) Variants Interact with the Normal CEL Protein in Pancreatic Cells 

      Valvatne, Monica Dalva; el Jellas, Khadija; Gravdal, Anny; Njølstad, Pål Rasmus; Molven, Anders; Fjeld, Karianne; Lugea, Aurelia; Pandol, Stephen J; Waldron, Richard T; Lavik, Ida; Johansson, Bente B. (Journal article; Peer reviewed, 2020)
      Mutations in the gene encoding the digestive enzyme carboxyl ester lipase (CEL) are linked to pancreatic disease. The CEL variant denoted CEL-HYB predisposes to chronic pancreatitis, whereas the CEL-MODY variant causes ...

    • Pathogens Associated With Linear Growth Faltering in Children With Diarrhea and Impact of Antibiotic Treatment: The Global Enteric Multicenter Study 

      Nasrin, Dilruba; Blackwelder, William C.; Sommerfelt, Halvor; Wu, Yukun; Farag, Tamer H.; Panchalingam, Sandra; Biswas, Kousick; Saha, Debasish; Jahangir Hossain, Hossain; Sow, Samba O.; Reiman, Robert F B; Sur, Dipika; Faruque, Abu Syed Golam; Zaidi, Anita K M; Sanogo, Doh; Tamboura, Boubou; Onwuchekwa, Uma; Manna, Byomkesh; Ramamurthy, Thandavarayan; Kanungo, Suman; Omore, Richard; Ochieng, John B.; Oundo, Joseph O.; Das, Sumon K.; Ahmed, Shahnawaz; Qureshi, Shahida; Quadri, Farheen; Adegbola, Richard A.; Antonio, Martin; Mandomando, Inacio; Nhampossa, Tacilta; Bassat, Quique; Roose, Anna; O'Reilly, Ciara E.; Mintz, Eric D.; Ramakrishnan, Usha; Powell, Helen; Liang, Yuanyuan; Nataro, James Paul; Levine, Myron M.; Kotloff, Karen L. (Journal article; Peer reviewed, 2021)
      Background The association between childhood diarrheal disease and linear growth faltering in developing countries is well described. However, the impact attributed to specific pathogens has not been elucidated, nor has ...

    • Pathological mechanisms in oral lichen planus : a atudy of apoptosis - regulatory proteins and risk markers for malignant transformation 

      Neppelberg, Evelyn (Doctoral thesis, 2007-05-04)
      Oral lichen planus (OLP) is a chronic mucocutaneous disease characterized by basal cell destruction and a subepithelial band-like mononuclear inflammatory cell infiltrate predominated by T cells. Molecular biological changes ...

    • Pathophysiological pathways in patients with heart failure and atrial fibrillation 

      Santema, Bernadet T.; Arita, Vicente Artola; Sama, Iziah E.; Kloosterman, Mariëlle; van den Berg, Maarten P.; Nienhuis, Hans L.A.; Van Gelder, Isabelle C.; van der Meer, Peter; Zannad, Faiez; Metra, Marco; Ter Maaten, Jozine M.; Cleland, John G.; Ng, Leong L.; Anker, Stefan D.; Lang, Chim C.; Samani, Nilesh J.; Dickstein, Kenneth; Filippatos, Gerasimos; van Veldhuisen, Dirk J.; Lam, Carolyn S.P.; Rienstra, Michiel; Voors, Adriaan A. (Journal article; Peer reviewed, 2022)
      Aims Atrial fibrillation (AF) and heart failure (HF) are two growing epidemics that frequently co-exist. We aimed to gain insights into the underlying pathophysiological pathways in HF patients with AF by comparing ...

    • Pathophysiological pathways related to high plasma growth differentiation factor 15 concentrations in patients with heart failure 

      Ceelen, Daan; Voors, Adriaan A.; Tromp, Jasper; van Veldhuisen, Dirk J.; Dickstein, Kenneth; de Boer, Rudolf A.; Lang, Chim C.; Anker, Stefan D.; Ng, Leong L.; Metra, Marco; Ponikowski, Piotr; Figarska, Sylwia M. (Journal article; Peer reviewed, 2022)
      Aims Elevated concentrations of growth differentiation factor 15 (GDF-15) in patients with heart failure (HF) have been consistently associated with worse clinical outcomes, but what disease mechanisms high GDF-15 ...

    • Pathophysiology of idiopathic gastroparesis and implications for therapy 

      Bekkelund, Mattis; Sangnes, Dag André; Hatlebakk, Jan Gunnar; Aabakken, Lars (Peer reviewed; Journal article, 2019)
      Objectives: Idiopathic gastroparesis is a gastric motility disorder characterized by chronic upper gastrointestinal symptoms and delayed gastric emptying without an identifiable underlying condition. This review summarizes ...

    • PathwayMatcher: proteoform-centric network construction enables fine-granularity multi-omics pathway mapping 

      Hernández Sánchez, Luis Francisco; Burger, Bram; Horro Marcos, Carlos; Fabregat, Antonio; Johansson, Stefan; Njølstad, Pål Rasmus; Barsnes, Harald; Hermjakob, Henning; Vaudel, Marc (Peer reviewed; Journal article, 2019-07-30)
      Background Mapping biomedical data to functional knowledge is an essential task in bioinformatics and can be achieved by querying identifiers (e.g., gene sets) in pathway knowledge bases. However, the isoform and ...

    • Pathways to accountability in rural Guatemala: A qualitative comparative analysis of citizen-led initiatives for the right to health of indigenous populations 

      Hernández, Alison; Ruano, Ana Lorena; Hurtig, Anna-Karin; Goicolea, Isabel; San Sebastián, Miguel; Flores, Walter (Peer reviewed; Journal article, 2019)
      Strengthening citizen-led accountability initiatives is a critical rights-based strategy for improving health services for indigenous and other marginalized populations. As these initiatives have gained prominence in health ...

    • Pathway‑level mutation analysis in primary high‑grade serous ovarian cancer and matched brain metastases 

      Duchnowska, Renata; Supernat, Anna Maria; Pęksa, Rafał; Łukasiewicz, Marta; Stokowy, Tomasz; Ronen, Roy; Dutkowski, Janusz; Umińska, Monika; Iżycka-Świeszewska, Ewa; Kowalczyk, Anna; Och, Waldemar; Rucińska, Monika; Olszewski, Wojciech P.; Mandat, Tomasz; Jarosz, Bożena; Bieńkowski, Michał; Biernat, Wojciech; Jassem, Jacek (Journal article; Peer reviewed, 2022)
      Brain metastases (BMs) in ovarian cancer (OC) are a rare event. BMs occur most frequently in high-grade serous (HGS) OC. The molecular features of BMs in HGSOC are poorly understood. We performed a whole-exome sequencing ...

    • Patient activation in adults attending appointments in general practice: a cross-sectional study 

      Hernar, Ingvild; Graue, Marit; Igland, Jannicke; Richards, David A; Riise, Hilde Kristin Refvik; Haugstvedt, Anne; Kolltveit, Beate-Christin Hope (Journal article; Peer reviewed, 2023)
      Background Patient activation refers to patients’ knowledge, confidence, skills, ability, beliefs, and willingness to manage their health and healthcare. Patient activation is an essential component of self-management and ...

    • Patient and health service delay in the diagnosis of pulmonary tuberculosis in Ethiopia 

      Demissie, Meaza; Lindtjørn, Bernt; Berhane, Yemane (Peer reviewed; Journal article, 2002-09-25)
      Background: Delay in the diagnosis of tuberculosis may worsen the disease, increase the risk of death and enhance tuberculosis transmission in the community. This study aims to determine the length of delay between the ...

    • Patient and health system costs of managing pregnancy and birth-related complications in sub-Saharan Africa: a systematic review 

      Mori, Amani Thomas; Binyaruka, Peter; Hangoma, Peter; Robberstad, Bjarne; Sandøy, Ingvild Fossgard (Journal article; Peer reviewed, 2020)
      Background Morbidity and mortality due to pregnancy and childbearing are high in developing countries. This study aims to estimate patient and health system costs of managing pregnancy and birth-related complications in ...

    • Patient and surgical factors affecting procedure duration and revision risk due to deep infection in primary total knee arthroplasty 

      Badawy, Mona; Espehaug, Birgitte; Fenstad, Anne Marie; Indrekvam, Kari; Dale, Håvard; Havelin, Leif Ivar; Furnes, Ove (Peer reviewed; Journal article, 2017-12-21)
      Background: The aim of this study was to assess which patient and procedure factors affected both the risk of infection as well as procedure duration. Additionally, to assess if procedure duration affected the revision ...

    • The patient at the centre: evidence from 17 European integrated care programmes for persons with complex needs 

      Czypionka, Thomas; Kraus, Markus; Reiss, Miriam; Roca, Josep; Ruths, Sabine; Stokes, Jonathan; Struckmann, Verena; Haček, Romana Tandara; Zemplényi, Antal; Hoedemakers, Maaike; Rutten-van Mölken, Maureen (Journal article; Peer reviewed, 2020)
      Background As the prevalence of multi-morbidity increases in ageing societies, health and social care systems face the challenge of providing adequate care to persons with complex needs. Approaches that integrate care ...

    • The patient at the centre: evidence from 17 European integrated care programmes for persons with complex needs 

      Czypionka, Thomas; Kraus, Markus; Reiss, Miriam; Baltaxe, Erik; Roca, Josep; Ruths, Sabine; Stokes, Jonathan; Struckmann, Verena; Haček, Romana Tandara; Zemplényi, Antal; Hoedemakers, Maaike; Rutten-van Mölken, Maureen (Journal article; Peer reviewed, 2020)
      Background As the prevalence of multi-morbidity increases in ageing societies, health and social care systems face the challenge of providing adequate care to persons with complex needs. Approaches that integrate care ...

    • Patient experience following iliac crest alveolar bone gradfting av implant replacement 

      Gjerde, Cecilie Gudveig; Mustafa, Kamal Babikeir Eln; Gjengedal, Harald; Shanbhag, Siddharth; Neppelberg, Evelyn (Journal article; Peer reviewed, 2020-02-05)
      Background The objective of this study was to assess patient-reported outcomes such as satisfaction and quality of life after advanced alveolar bone augmentation with anterior iliac crest grafting and implant treatment ...

    • Patient experiences and the association with organizational factors in general practice: results from the Norwegian part of the international, multi-centre, cross-sectional QUALICOPC study 

      Straand, Jørund; Melbye, Hasse; Rortveit, Guri; Hetlevik, Irene; Eide, Torunn Bjerve; Rosvold, Elin Olaug (Peer reviewed; Journal article, 2016-08-24)
      Background: General practitioners (GPs) constitute a vital part of a strong primary health care system. We need further knowledge concerning factors that may affect the patients’ experiences in their meetings with the GPs. ...