Browsing Faculty of Medicine by Title
Now showing items 6936-6955 of 9018
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Profiling and functional analysis of microRNA deregulation in cancer-associated fibroblasts in oral squamous cell carcinoma depicts an anti-invasive role of microRNA-204 via regulation of their motility
(Journal article; Peer reviewed, 2021-11-04)Background: Knowledge on the role of miR changes in tumor stroma for cancer progression is limited. This study aimed to investigate the role of miR dysregulation in cancer-associated fibroblasts (CAFs) in oral squamous ... -
Profylaktisk fjerning av visdomstenner: Fortsatt et smart trekk?
(Master thesis, 2020-02-20)Moderne odontologi blir praktisert med et fokus på profylakse. Fjerning av asymptomatiske visdomstenner gjøres profylaktisk for å skåne pasienten for tilstander som potensielt kan være alvorlige. Det finnes lite forskning ... -
Prognosis and Histological Classification in Elderly Patients with ANCA-Glomerulonephritis: A Registry-Based Cohort Study
(Peer reviewed; Journal article, 2018-05-31)Background. The value of a histologic classification scheme to classify patients with anti-neutrophil cytoplasmic antibody-associated glomerulonephritis (ANCA-GN) into focal, mixed, crescentic, and sclerotic types for ... -
Prognosis in asymptomatic patients with discordantly graded aortic valve stenosis based on pressure recovery adjusted valve area
(Journal article; Peer reviewed, 2022)Objective: We hypothesised that patients with asymptomatic aortic stenosis (AS) who remain with discordantly graded aortic valve stenosis (DGAS) after adjustment for pressure recovery in the aortic root represents a subgroup ... -
Prognostic and predictive impact of stroma cells defned by PDGFRb expression in early breast cancer: results from the randomized SweBCG91RT trial
(Journal article; Peer reviewed, 2021)Purpose Predictive biomarkers are needed to aid the individualization of radiotherapy (RT) in breast cancer. Cancer-associated fibroblasts have been implicated in tumor radioresistance and can be identified by platelet-derived ... -
Prognostic factors in anti-neutrophil cytoplasmic antibody-associated glomerulonephritis with severe glomerular sclerosis: a national registry-based cohort study
(Peer reviewed; Journal article, 2018-06-03)Background. Classification of patients with anti-neutrophil cytoplasmic antibody-associated glomerulonephritis (ANCA-GN) into histological classes is useful for predicting a patient’s risk of progression to end-stage renal ... -
Prognostic factors in renal cell carcinoma. A retrospective population based study focusing on the clear cell type
(Doctoral thesis, 2010-09-24) -
Prognostic Impact of In-Hospital and Postdischarge Heart Failure in Patients With Acute Myocardial Infarction: A Nationwide Analysis Using Data From the Cardiovascular Disease in Norway (CVDNOR) Project
(Peer reviewed; Journal article, 2017-03)Background: Heart failure (HF) is a serious complication of acute myocardial infarction (AMI). We explored the excess mortality associated with HF as an early or late complication of AMI and describe changes over time in ... -
Prognostic impact of vitamin B6 metabolism in lung cancer
(Peer reviewed; Journal article, 2012-08-30)Patients with non-small cell lung cancer (NSCLC) are routinely treated with cytotoxic agents such as cisplatin. Through a genome-wide siRNA-based screen, we identified vitamin B6 metabolism as a central regulator of cisplatin ... -
Prognostic models for the early care of trauma patients: a systematic review
(Peer reviewed; Journal article, 2011-03-20)Background: Early identification of major trauma may contribute to timely emergency care and rapid transport to an appropriate health-care facility. Several prognostic trauma models have been developed to improve early ... -
Prognostic performance of preoperative cardiac troponin and perioperative changes in cardiac troponin for the prediction of major adverse cardiac events and mortality in noncardiac surgery: A systematic review and meta-analysis
(Peer reviewed; Journal article, 2019-04-22)Background Increased postoperative cardiac troponin (cTn) independently predicts short-term mortality. Previous studies suggest that preoperative cTn also predicts major adverse cardiovascular events (MACE) and mortality ... -
Prognostic relevance of an epigenetic biomarker panel in sentinel lymph nodes from colon cancer patients
(Peer reviewed; Journal article, 2017-09-05)Background: Patients with early colorectal cancer (stages I–II) generally have a good prognosis, but a subgroup of 15–20% experiences relapse and eventually die of disease. Occult metastases have been suggested as a marker ... -
The prognostic relevance of interactions between venous invasion, lymph node involvement and distant metastases in renal cell carcinoma after radical nephrectomy
(Peer reviewed; Journal article, 2008-12-19)Background: To investigate a possible prognostic significance of interactions between lymph node invasion (LNI), synchronous distant metastases (SDM), and venous invasion (VI) adjusted for mode of detection, Eastern ... -
Prognostic significance of chronic myocardial injury diagnosed by three different cardiac troponin assays in patients admitted with suspected acute coronary syndrome
(Journal article; Peer reviewed, 2023)Objectives Chronic myocardial injury (CMI) is defined as stable concentrations of cardiac troponin T or I (cTnT or cTnI) above the assay-specific 99th percentile upper reference limit (URL) and signals poor outcome. The ... -
Prognostic significance of S100A4 expression in stage II and III colorectal cancer: results from a population-based series and a randomized phase III study on adjuvant chemotherapy
(Peer reviewed; Journal article, 2016-08)Current clinical algorithms are unable to precisely predict which colorectal cancer patients would benefit from adjuvant chemotherapy, and there is a need for novel biomarkers to improve the selection of patients. The ... -
Prognostic utility of vitamin D in acute coronary syndrome patients in coastal Norway
(Peer reviewed; Journal article, 2015)BACKGROUND: An inverse relationship between cardiovascular risk and levels of vitamin D and omega-3 index may exist. OBJECTIVES: To evaluate the prognostic utility of serum 25-hydroxyvitamin D [25(OH)D] in 871 patients ... -
Prognostic value of baseline functional status measures and geriatric screening in vulnerable older patients with metastatic colorectal cancer receiving palliative chemotherapy – The randomized NORDIC9-study
(Journal article; Peer reviewed, 2023)Introduction Appropriate patient selection based on functional status is crucial when considering older adults for palliative chemotherapy. This pre-planned analysis of the randomized NORDIC9-study explored the prognostic ... -
Prognostic value of bone marrow involvement by clonal immunoglobulin gene rearrangements in follicular lymphoma
(Peer reviewed; Journal article, 2014-09-18)Aims: We aimed to evaluate the prognostic value of routine use of PCR amplification of immunoglobulin gene rearrangements in bone marrow (BM) staging in patients with follicular lymphoma (FL). Methods: Clonal rearrangements ... -
Prognostic value of different anthropometric indices over different measurement intervals to predict mortality in 6-59-month-old children
(Journal article; Peer reviewed, 2023)Objective: To compare the prognostic value of mid-upper arm circumference (MUAC), weight-for-height Z-score (WHZ) and weight-for-age Z-score (WAZ) for predicting death over periods of 1, 3 and 6 months follow-up in ...