Browsing Faculty of Medicine by Title

Now showing items 7235-7254 of 8886

    • Reproducibility and prognostic value of WHO1973 and WHO2004 grading systems in TaT1 urothelial carcinoma of the urinary bladder 

      Mangrud, Målfrid Ok; Waalen, Rune; Gudlaugsson, Einar; Dalen, Ingvild; Tasdemir, Ilker; Janssen, Emilius Adrianus Maria; Baak, Jan P.A. (Peer reviewed; Journal article, 2014-01-07)
      Background: European treatment guidelines of TaT1 urinary bladder urothelial carcinomas depend highly on stage and WHO1973-grade but grading reproducibility is wanting. The newer WHO2004 grading system is still debated and ...

    • A reproducible brain tumour model established from human glioblastoma biopsies 

      Wang, Jian; Miletic, Hrvoje; Sakariassen, Per Øystein; Huszthy, Peter Csaba; Jacobsen, Hege; Brekkå, Narve; Li, Xingang; Zhao, Peng; Mørk, Sverre; Chekenya, Martha; Bjerkvig, Rolf; Enger, Per Øyvind (Peer reviewed; Journal article, 2009-12-29)
      Background: Establishing clinically relevant animal models of glioblastoma multiforme (GBM) remains a challenge, and many commonly used cell line-based models do not recapitulate the invasive growth patterns of patient ...

    • Reproduction and marriage among male survivors of cancer in childhood, adolescence and young adulthood: a national cohort study 

      Gunnes, Maria Winther; Lie, Rolv Terje; Bjørge, Tone; Ghaderi, Sara; Ruud, Ellen; Syse, Astri; Moster, Dag (Peer reviewed; Journal article, 2016)
      Background: Increased survival after cancer in young age has made long-term follow-up studies of high external validity important. In this national cohort study, we explored the impact of cancer in young age on reproduction ...

    • Reproductive and family planning history, knowledge, and needs: A community survey of low-income women in Beijing, China 

      He, Hong; Østbye, Truls; Daltveit, Anne Kjersti (Peer reviewed; Journal article, 2009-08-10)
      Background: The reproductive health status of China's low-income urban women is believed to be poor. Therefore, understanding their reproductive history and needs and improving services provision is very important. However, ...

    • Reproductive history and risk of colorectal adenocarcinoma in parous women: a Nordic population-based case–control study 

      Bjørge, Tone; Gissler, Mika; Ording, Anne Gulbech; Engeland, Anders; Glimelius, Ingrid; Leinonen, Maarit; Sørensen, Henrik Toft; Tretli, Steinar; Ekbom, Anders; Troisi, Rebecca; Grotmol, Tom (Peer reviewed; Journal article, 2016-10-04)
      Background: Data are conflicting regarding the role of endogenous sex hormones in colorectal carcinogenesis. In this large population-based study, we pooled data from birth and cancer registries in four Nordic countries, ...

    • Reproductive trends in females with inflammatory joint disease 

      Wallenius, Marianne; Salvesen, Kjell Å; Daltveit, Anne Kjersti; Skomsvoll, Johan F (Peer reviewed; Journal article, 2016-05-31)
      Background: The study assessed birth trends per decade in offspring of females with inflammatory joint diseases (IJD) compared with women without IJD. Methods: This retrospective cohort study is based on data from the ...

    • Reprogrammed Cells Display Distinct Proteomic SignaturesAssociated with Colony Morphology Variability 

      Bjørlykke, Yngvild; Søviknes, Anne Mette; Hoareau, Laurence; Vethe, Heidrun; Mathisen, Andreas; Chera, Simona; Vaudel, Marc; Ghila, Luiza; Ræder, Helge (Peer reviewed; Journal article, 2019-11-18)
      Human induced pluripotent stem cells (hiPSCs) are of high interest because they can be differentiated into a vast range of different cell types. Ideally, reprogrammed cells should sustain long-term culturing in an ...

    • Repurposing 18F-FMISO as a PET tracer for translational imaging of nitroreductase-based gene directed enzyme prodrug therapy 

      Ruiz de Garibay, Gorka; García de Jalón, Elvira; Stigen, Endre; Lund, Kjetil B.; Popa, Mihaela-Lucia; Davidson, Ben; Mayoral Safont, Mireia; Rygh, Cecilie Brekke; Espedal, Heidi; Barrett, Torill; Haug, Bengt Erik; McCormack, Emmet (Journal article; Peer reviewed, 2021)
      Nitroreductases (NTR) are a family of bacterial enzymes used in gene directed enzyme prodrug therapy (GDEPT) that selectively activate prodrugs containing aromatic nitro groups to exert cytotoxic effects following gene ...

    • Repurposing chlorpromazine for anti-leukaemic therapy by nanoparticle encapsulation 

      Gundersen, Edvin Tang; Førde, Jan-Lukas; Tislevoll, Benedicte Sjo; Leitch, Calum; Barratt, Gillian; Gjertsen, Bjørn Tore; Herfindal, Lars (Journal article; Peer reviewed, 2022)
      Treatment of acute myeloid leukaemia (AML) relies on decades-old drugs, and while recent years have seen some breakthroughs, AML is still characterised by poor prognosis and survival rate. Drug repurposing can expedite the ...

    • A Research and Development (R&D) roadmap for influenza vaccines: Looking toward the future 

      Moore, Kristine A.; Ostrowsky, Julia T.; Kraigsley, Alison M.; Mehr, Angela J.; Bresee, Joseph S.; Friede, Martin H.; Gellin, Bruce G.; Golding, Josephine P.; Hart, Peter J.; Moen, Ann; Weller, Charlotte L.; Osterholm, Michael T.; Ampofo, William; Barclay, Wendy; Cavaleri, Marco; Cohen, Cheryl; Cowling, Benjamin; Cox, Rebecca Jane; Gust, Ian; Innis, Bruce; Kang, Gagandeep; Katz, Jacqueline M.; Krammer, Florian; Pitisuttithum, Punnee; Post, Diane; Rudenko, Larisa; Siqueira, Marilda M.; Weir, Jerry P. (Journal article; Peer reviewed, 2021)
      Improved influenza vaccines are urgently needed to reduce the burden of seasonal influenza and to ensure a rapid and effective public-health response to future influenza pandemics. The Influenza Vaccines Research and ...

    • Research protocol local ingredients-based supplementary food as an alternative to corn-soya blends plus for reatingmoderate acute malnutrition among children aged 6 to 59 months: a randomized controlled non-inferiority trial in Wolaita 

      Nane, Debritu; Hatløy, Anne; Tadesse, Elazar; Lindtjorn, Bernt (Peer reviewed; Journal article, 2019)
      Background In Ethiopia, 12.5% of children below 5 years are wasted, and 9.7% are moderately wasted. The present strategy for the management of moderate acute malnutrition (MAM) is a supplementary feeding program; however, ...

    • Research Review: Recommendations for reporting on treatment trials for child and adolescent anxiety disorders – an international consensus statement 

      Creswell, Cathy; Nauta, Maaike; Hudson, Jennifer L.; March, Sonja; Reardon, Tessa; Arendt, Kristian; Bodden, Denise; Cobham, Vanessa E.; Donovan, Caroline; Halldorsson, Brynjar; In-Albon, Tina; Ishikawa, Shin-ichi; Johnsen, Daniel Bach; Jolstedt, Maral; de Jong, Rachel; Kreuze, Leonie; Mobach, Lynn; Rapee, Ronald M.; Spence, Susan H.; Thastum, Mikael; Utens, Elisabeth; Vigerland, Sarah; Wergeland, Gro Janne; Essau, Cecilia A.; Albano, Anne Marie; Chu, Brian; Khanna, Muniya; Silverman, Wendy K.; Kendall, Philip C. (Journal article; Peer reviewed, 2020)
      Background Anxiety disorders in children and young people are common and bring significant personal and societal costs. Over the last two decades, there has been a substantial increase in research evaluating psychological ...

    • Researcher-researched relationship in qualitative research: Shifts in positions and researcher vulnerability 

      Råheim, Målfrid; Magnussen, Liv Heide; Sekse, Ragnhild Johanne Tveit; Lunde, Åshild; Jacobsen, Torild; Blystad, Astrid (Peer reviewed; Journal article, 2016-06-14)
      Background: The researcher role is highly debated in qualitative research. This article concerns the researcher-researched relationship. Methods: A group of health science researchers anchored in various qualitative research ...

    • Resection of asymptomatic primary tumour in unresectable stage IV colorectal cancer: time to move on from propensity matched scores to randomized controlled trials 

      Søreide, Kjetil (Journal article, 2016-11)

    • Resection rates and predictors of survival after surgery for colorectal liver metastases 

      Angelsen, Jon-Helge (Doctoral thesis, 2017-10-20)
      Introduction: Occurrence of liver metastases is common following colorectal cancer (CRC), and resection is the only option with a potential for cure offered to a minor part of these patients. During the last decades there ...

    • Resibufogenin Targets the ATP1A1 Signaling Cascade to Induce G2/M Phase Arrest and Inhibit Invasion in Glioma 

      Zhang, Xun; Yao, Zhong; Xue, Zhiyi; Wang, Shuai; Liu, Xuemeng; Hu, Yaotian; Zhang, Yan; Wang, Jian; Li, Xingang; Chen, Anjing (Journal article; Peer reviewed, 2022)
      Resibufogenin (RB) is a major active ingredient in the traditional Chinese medicine Chansu and has garnered considerable attention for its efficacy in the treatment of cancer. However, the anticancer effects and underlying ...

    • Residential greenspace and lung function decline over 20 years in a prospective cohort: The ECRHS study 

      Markevych, Iana; Zhao, Tianyu; Fuertes, Elaine; Marcon, Alessandro; Dadvand, Payam; Vienneau, Danielle; Garcia Aymerich, Judith; Nowak, Dennis; de Hoogh, Kees; Jarvis, Deborah; Abramson, Michael J.; Accordini, Simone; Amaral, Andre FS; Bentouhami, Hayat; Bertelsen, Randi Jacobsen; Boudier, Anne; Bono, Roberto; Bowatte, Gayan; Casas, Lidia; Dharmage, Shyamali C; Forsberg, Bertil; Gislason, Thorarinn; Gnesi, Marco; Holm, Mathias; Jacquemin, Benedicte; Janson, Christer; Jogi, Rain; Johannessen, Ane; Keidel, Dirk; Leynaert, Benedicte; Maldonado Perez, José Antonio; Marchetti, Pierpaolo; Migliore, Enrica; Martínez-Moratalla, Jesús; Orru, Hans; Pin, Isabelle; Potts, James; Probst-Hensch, Nicole; Ranzi, Andrea; Sánchez-Ramos, José Luis; Siroux, Valerie; Soussan, David; Sunyer, Jordi; Urrutia Landa, Isabel; Villani, Simona; Heinrich, Joachim (Journal article; Peer reviewed, 2023)
      Background: The few studies that have examined associations between greenspace and lung function in adulthood have yielded conflicting results and none have examined whether the rate of lung function decline is ...

    • Residential surrounding greenspace and age at menopause: A 20-year European study (ECRHS) 

      Triebner, Kai; Markevych, Iana; Hustad, Simon Steinar; Benediktsdóttir, Bryndís; Forsberg, Bertil; Franklin, Karl A.; Gullón Blanco, José Antonio; Holm, Mathias; Jaquemin, Bénédicte; Jarvis, Debbie; Jõgi, Rain; Leynaert, Bénédicte; Lindberg, Eva; Martínez-Moratalla, Jesús; Muniozguren Agirre, Nerea; Pin, Isabelle; Sánchez-Ramos, José Luis; Heinrich, Joachim; Gomez Real, Francisco; Dadvand, Payam (Peer reviewed; Journal article, 2019-08-19)
      Background Menopause is associated with a number of adverse health effects and its timing has been reported to be influenced by several lifestyle factors. Whether greenspace exposure is associated with age at menopause has ...

    • Residents’ perceptions of their own sadness - a qualitative study in Norwegian nursing homes 

      Iden, Kristina Riis; Ruths, Sabine; Hjørleifsson, Stefan (Peer reviewed; Journal article, 2015-03-08)
      Background: Mood symptoms are highly prevalent among frail old people residing in nursing homes. Systematic diagnostics of depression is scarce, and treatment is not always in accordance with best evidence. The distinction ...

    • Residual Corticosteroid Production in Autoimmune Addison Disease 

      Sævik, Åse Bjorvatn; Åkerman, Anna-Karin; Methlie, Paal; Quinkler, Marcus; Jørgensen, Anders Palmstrøm; Høybye, Charlotte; Debowska, Aleksandra; Nedrebø, Bjørn Gunnar; Dahle, Anne Lise; Carlsen, Siri; Tomkowicz, Aneta; Sollid, Stina Therese; Nermoen, Ingrid; Grønning, Kaja; Dahlqvist, Per; Grimnes, Guri; Skov, Jakob; Finnes, Trine Elisabeth; Valland, Susanna Fonneland; Wahlberg, Jeanette; Holte, Synnøve Emblem; Simunkova, Katerina; Kämpe, Olle; Husebye, Eystein Sverre; Bensing, Sophie; Øksnes, Marianne (Journal article; Peer reviewed, 2020)
      Design: Two-staged, cross-sectional clinical study in 17 centers (Norway, Sweden, and Germany). Residual glucocorticoid (GC) production was defined as quantifiable serum cortisol and 11-deoxycortisol and residual ...