Browsing Faculty of Medicine by Title
Now showing items 973-992 of 8886
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Can traditional risk factors explain the higher risk of cardiovascular disease in South Asians compared to Europeans in Norway and New Zealand? Two cohort studies
(Peer reviewed; Journal article, 2017)Objectives: The objective was to prospectively examine potential differences in the risk of first cardiovascular disease (CVD) events between South Asians and Europeans living in Norway and New Zealand, and to investigate ... -
Can We Optimize Antibiotic Use in Norwegian Neonates? A Prospective Comparison Between a University Hospital and a District Hospital
(Peer reviewed; Journal article, 2019)Background: Worldwide, a large proportion of neonates are prescribed antibiotics without having infections leading to increased antimicrobial resistance, disturbance of the evolving microbiota, and increasing the risk of ... -
Can we rely on simulated patients' satisfaction with their consultation for assessing medical students' communication skills? A cross-sectional study
(Peer reviewed; Journal article, 2015-12-18)Background. In medical education, teaching methods offering intensive practice without high utilization of faculty resources are needed. We investigated whether simulated patients’ (SPs’) satisfaction with a consultation ... -
Cancer and stroke: commonly encountered by clinicians, but little evidence to guide clinical approach
(Journal article; Peer reviewed, 2022)The association between stroke and cancer is well-established. Because of an aging population and longer survival rates, the frequency of synchronous stroke and cancer will become even more common. Different pathophysiologic ... -
Cancer and Total Hip Replacement. Cancer as a risk factor for prosthesis and prosthesis as a risk factor for cancer
(Doctoral thesis, 2015-09-18)Annually, 14 million new cancer cases are detected worldwide; the numbers are expected to rise by 70% over the next decades. In Norway, 30,000 new cancer cases are detected every year. Because of screenings and increased ... -
Cancer awareness in the general population varies with sex, age and media coverage: A population-based survey with focus on gynecologic cancers
(Journal article; Peer reviewed, 2021)Objectives There is a need for more knowledge about the public awareness and attitudes towards gynecologic cancers. We employed a research-purpose population-based citizen panel to assess how often people recall gynecologic ... -
Cancer cachexia associates with a systemic autophagy-inducing activity mimicked by cancer cell-derived IL-6 trans-signaling
(Peer reviewed; Journal article, 2017-05-17)The majority of cancer patients with advanced disease experience weight loss, including loss of lean body mass. Severe weight loss is characteristic for cancer cachexia, a condition that significantly impairs functional ... -
Cancer cell heterogeneity and plasticity: A paradigm shift in glioblastoma
(Journal article; Peer reviewed, 2022)Phenotypic plasticity has emerged as a major contributor to intra-tumoral heterogeneity and treatment resistance in cancer. Increasing evidence shows that glioblastoma (GBM) cells display prominent intrinsic plasticity and ... -
Cancer cell line-specific protein profiles in extracellular vesicles identified by proteomics
(Journal article; Peer reviewed, 2020-09-04)Extracellular vesicles (EVs), are important for intercellular communication in both physiological and pathological processes. To explore the potential of cancer derived EVs as disease biomarkers for diagnosis, monitoring, ... -
Cancer epigenetics in solid organ tumours: A primer for surgical oncologists
(Peer reviewed; Journal article, 2019-05)Cancer is initiated through both genetic and epigenetic alterations. The end-effect of such changes to the DNA machinery is a set of uncontrolled mechanisms of cell division, invasion and, eventually, metastasis. Epigenetic ... -
Cancer in ANCA-Associated Glomerulonephritis: A Registry-Based Cohort Study
(Peer reviewed; Journal article, 2017-12-18)Background. Immunosuppressive therapy for antineutrophil cytoplasmic antibody-associated vasculitis has been associated with increased malignancy risk. Objectives. To quantify the cancer risk associated with contemporary ... -
Cancer patients’ use of primary care out-of-hours services: a cross-sectional study in Norway
(Peer reviewed; Journal article, 2016)Objective: To investigate how cancer patients in Norway use primary care out-of-hours (OOH) services and describe different contact types and procedures. Design: A retrospective cross-sectional registry study using a billing ... -
Cancer Predisposition Sequencing Reporter (CPSR): A flexible variant report engine for high-throughput germline screening in cancer
(Journal article; Peer reviewed, 2021)The value of high-throughput germline genetic testing is increasingly recognized inclinical cancer care. Disease-associated germline variants in cancer patients areimportant for risk management and surveillance, surgical ... -
The Cancer Registry of Norway – “a ground for scientific harvesting”
(Journal article; Peer reviewed, 2022)The Cancer Registry of Norway (CRN) has been important in registry-based research in Norway for decades. The use of CRN in combination with other population-based registries and health surveys have been the basis for ... -
Cancer related mortality in multiple sclerosis. A population based cohort study
(Journal article; Peer reviewed, 2023)Background: Cancer is a major cause of death, but how cancer influences mortality risk in Multiple Sclerosis (MS) is unclear. Objectives: Determine all-cause mortality and mortality following a cancer diagnosis among ... -
Cancer risk in children of mothers with epilepsy and high-dose folic acid use during pregnancy
(Journal article; Peer reviewed, 2022)Importance: Women with epilepsy are recommended high doses of folic acid before and during pregnancy owing to risk of congenital anomalies associated with antiseizure medications. Whether prenatal exposure to high-dose ... -
Cancer risk in individuals with major birth defects: large Nordic population based case-control study among children, adolescents, and adults
(Journal article; Peer reviewed, 2020)Objective To examine associations between birth defects and cancer from birth into adulthood. Design Population based nested case-control study. Setting Nationwide health registries in Denmark, Finland, Norway, ... -
Cancer risk in the siblings of individuals with major birth defects: a large Nordic population-based case-control study
(Journal article; Peer reviewed, 2023)Background: Individuals with major birth defects are at increased risk of developing cancer, indicating a common aetiology. However, whether the siblings of individuals with birth defects are also at an increased risk of ... -
Cancer Stem Cell-Related Markers in Normal and Neoplastic Oral Mucosa. A study on human samples and experimental models
(Doctoral thesis, 2014-06-04)The existence of cancer stem cells (CSCs) in solid cancers is still a controversial issue. Several markers were successfully used to enrich for cells with stem cell-like properties in oral squamous cell carcinoma (OSCC). ... -
Cancer stem cells as mediators of treatment resistance in brain tumors: Status and controversies
(Peer reviewed; Journal article, 2007-11)Malignant primary brain tumors are characterized by a short median survival and an almost 100% tumorrelated mortality. Despite the addition of new chemotherapy regimes, the overall survival has improved marginally, and ...