• Detection of Arc/Arg3.1 oligomers in rat brain: constitutive and synaptic activity-evoked dimer expression in vivo 

      Mergiya, Tadiwos Feyissa; Gundersen, Jens Edvard Trygstad; Kanhema, Tambudzai; Brighter, Grant Mitchell; Ishizuka, Yuta; Bramham, Clive Raymond Evjen (Journal article; Peer reviewed, 2023)
      The immediate early gene product activity-regulated cytoskeleton-associated protein (Arc or Arg3.1) is a major regulator of long-term synaptic plasticity with critical roles in postnatal cortical development and memory ...
    • Detection of Nonadherence to Antihypertensive Treatment by Measurements of Serum Drug Concentrations 

      Bergland, Ola Undrum; Halvorsen, Lene Vernås; Søraas, Camilla Lund; Hjørnholm, Ulla; Kjær, Vibeke Norheim; Rognstad, Stine; Brobak, Karl Marius; Aune, Arleen; Olsen, Eirik; Fauchald, Ylva; Heimark, Sondre; Thorstensen, Christian W; Liestøl, Knut; Solbu, Marit Dahl; Gerdts, Eva; Mo, Rune; Rostrup, Morten; Kjeldsen, Sverre; Høieggen, Aud; Opdal, Mimi Stokke; Fadl Elmula, Fadl Elmula M. (Journal article; Peer reviewed, 2021)
      Nonadherence to drugs is a challenge in hypertension treatment. We aimed to assess the prevalence of nonadherence by serum drug concentrations compared with 2 indirect methods and relate to the prescribed drug regimens in ...
    • Detection of pulmonary tuberculosis among patients with cough attending outpatient departments in Dar Es Salaam, Tanzania: does duration of cough matter? 

      Ngadaya, Esther S.; Mfinanga, Sayoki Godfrey; Wandwalo, Eliud R.; Mørkve, Odd (Peer reviewed; Journal article, 2009-07-01)
      Background: According to WHO estimates, tuberculosis case detection rate in Tanzania is less than 50% and this poses a major challenge to control tuberculosis in the country. Currently, one of the defining criteria for ...
    • Detection of remaining Plasmodium DNA and gametocytes during follow up after curative malaria treatment among returned travellers in Norway 

      Haanshuus, Christel Gill; Mørch, Kristine (Journal article; Peer reviewed, 2020)
      Background PCR can be positive weeks after effective malaria treatment, potentially leading to over diagnose of recrudescence and re-infections. The DNA detected by PCR post-treatment might stem from residuals of destroyed ...
    • Deteksjon av tidlige veggforandringer i halsarterier hos barn og unge med type-1 diabetes 

      Gaarder, Mario (Master thesis, 2010-05-14)
      Detection of early changes in the carotid artery walls in children and adolescents with type-1 diabetes. Background and objectives. Diabetics have twice the mortality rate as non-diabetics, atherosclerosis being the main ...
    • Determinants and Consequences of Nutritional Status in Patients with Chronic Kidney Disease 

      Dahl, Helene (Doctoral thesis, 2022-10-20)
      Bakgrunn: Pasienter med kronisk nyresykdom møter mangfoldige utfordringer vedrørende deres ernæringsstatus, relatert til redusert nyrefunksjon, påfølgende metabolske forandringer, mangfoldige komorbiditeter og polyfarmasi. ...
    • Determinants of airborne benzene evaporating from fresh crude oils released into seawater 

      Gjesteland, Ingrid; Hollund, Bjørg Eli; Kirkeleit, Jorunn; Daling, Per Snorre; Sørheim, Kristin Rist (Peer reviewed; Journal article, 2019-03)
      Benzene, toluene, ethylbenzene, xylenes, naphthalene and n-hexane evaporating from a thin oil film was measured for 30 min in a small-scale test system at 2 and 13 °C and the impact of physicochemical properties on airborne ...
    • Determinants of Cognitive Development in the Early Life of Children in Bhaktapur, Nepal 

      Ranjitkar, Suman; Hysing, Mari; Kvestad, Ingrid; Shrestha, Merina; Ulak, Manjeswori; Shilpakar, Jaya Shree; Sintakala, Roshan; Chandyo, Ram Krishna; Shrestha, Laxman; Strand, Tor A (Peer reviewed; Journal article, 2019-12-06)
      Background: Children in low and middle income countries may have many risk factors for poor cognitive development, and are accordingly at a high risk of not reaching their developmental potential. Determinants for cognitive ...
    • Determinants of fractional exhaled nitric oxide in healthy men and women from the European Community Respiratory Health Survey III 

      Nerpin, Elisabet; Olivieri, Mario; Gislason, Thorainn; Olin, Anna C.; Nielsen, Rune; Johannessen, Ane; Ferreira, Diogenes S.; Marcon, Alessandro; Cazzoletti, Lucia; Accordini, Simone; Pin, Isabelle; Corsico, Angelo; Demoly, Pascal; Weyler, Joost; Nowak, Dennis; Jõgi, Rain; Forsberg, Bertil; Zock, Jan P.; Sigsgaard, Torben; Heinric, Joachim; Bono, Roberto; Leynaert, Bénédicte; Jarvis, Deborah; Janson, Christer; Malinovschi, Anderi (Peer reviewed; Journal article, 2019)
      Introduction: The fractional exhaled nitric oxide (FENO ) is a marker for type 2 inflammation used in diagnostics and management of asthma. In order to use FENO as a reliable biomarker, it is important to investigate factors ...
    • Determinants of Health Facility Utilization at Birth in South Sudan 

      Tongun, Justin Bruno; Mukunya, David; Tylleskär, Thorkild; Sebit, Mohammed Boy; Tumwine, James K; Ndeezi, Grace (Peer reviewed; Journal article, 2019-07-09)
      South Sudan has a high maternal mortality ratio estimated at 800 deaths per 100,000 live births. Birth in health facilities with skilled attendants can lower this mortality. In this cross-sectional study, we determined the ...
    • Determinants of infant growth in Eastern Uganda: a community-based cross-sectional study 

      Engebretsen, Ingunn Marie S.; Tylleskär, Thorkild; Wamani, Henry; Karamagi, Charles A. S.; Tumwine, James K. (Peer reviewed; Journal article, 2008-12-22)
      Background: Child under-nutrition is a leading factor underlying child mortality and morbidity in Sub- Saharan Africa. Several studies from Uganda have reported impaired growth, but there have been few if any community-based ...
    • Determinants of interindividual variation in exercise-induced cardiac troponin I levels 

      Bjørkavoll-Bergseth, Magnus; Erevik, Christine Bjørkvik; Kleiven, Øyunn; Eijsvogels, Thijs M. H.; Skadberg, Øyvind; Frøysa, Vidar; Wiktorski, Tomasz; Auestad, Bjørn; Edvardsen, Thor; Aakre, Kristin Moberg; Ørn, Stein (Journal article; Peer reviewed, 2021)
      Background: Postexercise cardiac troponin levels show considerable interindividual variations. This study aimed to identify the major determinants of this postexercise variation in cardiac troponin I (cTnI) following 3 ...
    • Determinants of ligand binding and catalytic activity in the myelin enzyme 2′,3′-cyclic nucleotide 3′-phosphodiesterase 

      Raasakka, Arne; Myllykoski, Matti; Laulumaa, Saara; Lehtimäki, Mari; Härtlein, Michael; Moulin, Martine; Kursula, Inari; Kursula, Petri (Peer reviewed; Journal article, 2015-11-13)
      2′,3′-cyclic nucleotide 3′-phosphodiesterase (CNPase) is an enzyme highly abundant in the central nervous system myelin of terrestrial vertebrates. The catalytic domain of CNPase belongs to the 2H phosphoesterase superfamily ...
    • Determinants of male involvement in the prevention of mother-to-child transmission of HIV programme in Eastern Uganda: a cross-sectional survey 

      Byamugisha, Robert; Tumwine, James K.; Semiyaga, Nulu; Tylleskär, Thorkild (Peer reviewed; Journal article, 2010-06-23)
      Background: Mother-to-child transmission of HIV (MTCT) accounts for over 95% of all paediatric HIV infections worldwide. Several studies have shown that male participation in the antenatal care of their spouses together ...
    • Determinants of penetrance and variable expressivity in monogenic metabolic conditions across 77,184 exomes 

      Goodrich, Julia K.; Singer-Berk, Moriel; Son, Rachel; Sveden, Abigail; Wood, Jordan; England, Eleina; Cole, Joanne B.; Weisburd, Ben; Watts, Nick; Caulkins, Lizz; Dornbos, Peter; Koesterer, Ryan; Zappala, Zachary; Zhang, Haichen; Maloney, Kristin A.; Dahl, Andy; Aguilar-Salinas, Carlos A.; Atzmon, Gil; Barajas-Olmos, Francisco; Barzilai, Nir; Blangero, John; Boerwinkle, Eric; Bonnycastle, Lori L.; Bottinger, Erwin; Bowden, Donald W.; Centeno-Cruz, Federico; Chambers, John C.; Chami, Nathalie; Chan, Edmund; Chan, Juliana; Cheng, Ching-Yu; Cho, Yoon Shin; Contreras-Cubas, Cecilia; Córdova, Emilio; Correa, Adolfo; DeFronzo, Ralph A.; Duggirala, Ravindranath; Dupuis, Josée; Garay-Sevilla, Ma Eugenia; García-Ortiz, Humberto; Gieger, Christian; Glaser, Benjamin; González-Villalpando, Clicerio; Gonzalez, Ma Elena; Grarup, Niels; Groop, L; Gross, Myron; Haiman, Christopher A.; Han, Sohee; Hanis, Craig L.; Hansen, Torben; Heard-Costa, Nancy L.; Henderson, Brian E.; Hernandez, Juan Manuel Malacara; Hwang, Mi Yeong; Islas-Andrade, Sergio; Jørgensen, Marit E.; Kang, Hyun Min; Kim, Bong-Jo; Kim, Young Jin; Koistinen, Heikki A.; Kooner, Jaspal Singh; Kuusisto, Johanna; Kwak, Soo-Heon; Laakso, Markku; Lange, Leslie; Lee, Jong-Young; Lee, Juyoung; Lehman, Donna M.; Linneberg, Allan; Liu, Jianjun; Loos, Ruth J. F.; Lyssenko, Valeriya; Ma, Ronald C. W.; Martínez-Hernández, Angélica; Meigs, James B.; Meitinger, Thomas; Mendoza-Caamal, Elvia; Mohlke, Karen L.; Morris, AD; Morrison, Alanna C.; Ng, Maggie C. Y.; Nilsson, Peter M.; O’Donnell, Christopher J.; Orozco, Lorena; Palmer, Colin N. A.; Park, Kyong Soo; Post, W; Pedersen, Oluf; Preuss, Michael; Psaty, Bruce M.; Reiner, Alexander P.; Revilla-Monsalve, Cristina; Rich, Stephen S.; Rotter, Jerome I.; Saleheen, Danish; Schurmann, Claudia; Sim, Xueling; Sladek, Rob; Small, Kerrin S.; So, Wing Yee; Spector, Timothy D.; Strauch, Konstantin; Strom, Tim M.; Tai, E. Shyong; Tam, Claudia H. T.; Teo, Yik Ying; Thameem, Farook; Tomlinson, Brian; Tracy, Russell P.; Tuomi, Tiinamaija; Tuomilehto, Jaakko; Tusié-Luna, Teresa; van Dam, Rob M.; Vasan, Ramachandran S.; Wilson, James G.; Witte, Daniel R.; Wong, Tien-Yin; Burtt, Noël P.; Zaitlen, Noah; McCarthy, Mark I.; Boehnke, Michael; Pollin, Toni I.; Flannick, Jason; Mercader, Josep M.; O’Donnell-Luria, Anne; Baxter, Samantha; Florez, Jose C.; MacArthur, Daniel G.; Udler, MS (Journal article; Peer reviewed, 2021)
      Hundreds of thousands of genetic variants have been reported to cause severe monogenic diseases, but the probability that a variant carrier develops the disease (termed penetrance) is unknown for virtually all of them. ...
    • Determinants of periodontal health in pregnant women and association with infants’ anthropometric status: a prospective cohort study from Eastern Uganda 

      Wandera, Margaret Nekesa; Åstrøm, Anne Nordrehaug; Okullo, Isaac; Tumwine, James K. (Peer reviewed; Journal article, 2012-09-05)
      Background: Preterm-low birth weight delivery is a major cause of infant morbidity and mortality in sub Saharan Africa and has been linked to poor periodontal health during pregnancy. This study investigated predisposing ...
    • Determinants of self-perceived risk of HIV infection: population-based observations in Zambia 

      Mwangala, Sheila Monde (Master thesis, 2008-06-06)
      Background Perception of risk of HIV infection has been suggested to be an important area of study as it can be an assumed to be an indicator of one’s understanding of susceptibility to HIV infection and a precursor to ...
    • Determinants of trabecular bone score and prevalent vertebral fractures in women with fragility fractures: a cross-sectional sub-study of NoFRACT 

      Borgen, Tove Tveitan; Bjørnerem, Åshild; Solberg, Lene Bergendal; Andreasen, Camilla; Figved, Wender; Hübschle, Lars Michael; Stenbro, May-Britt; Basso, Trude; Dahl, cecilie; Stutzer, Jens-Meinhard; Frihagen, Frede; Eriksen, Erik Fink; Nordsletten, Lars; Hansen, Ann Kristin; Apalset, Ellen Margrete; Gjertsen, Jan Erik; Lund, Ida (Peer reviewed; Journal article, 2020)
      Summary: Determinants of trabecular bone score (TBS) and vertebral fractures assessed semiquantitatively (SQ1–SQ3) were studied in 496 women with fragility fractures. TBS was associated with age, parental hip fracture, ...
    • Determinants of Treatment Adherence Among Smear-Positive Pulmonary Tuberculosis Patients in Southern Ethiopia 

      Shargie, Estifanos Biru; Lindtjørn, Bernt (PLoS Medicine 2007 4(2): e37, Peer reviewed; Journal article, 2007-02-13)
      Background: Defaulting from treatment remains a challenge for most tuberculosis control programmes. It may increase the risk of drug resistance, relapse, death, and prolonged infectiousness. The aim of this study was to ...