Blar i Faculty of Medicine på tittel
Viser treff 5568-5587 av 8877
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An mri-based radiomic prognostic index predicts poor outcome and specific genetic alterations in endometrial cancer
(Journal article; Peer reviewed, 2021)Integrative tumor characterization linking radiomic profiles to corresponding gene expression profiles has the potential to identify specific genetic alterations based on non-invasive radiomic profiling in cancer. The aim ... -
MRPS23 amplification and gene expression in breast cancer; association with proliferation and the non-basal subtypes
(Journal article; Peer reviewed, 2020-01-16)Purpose MRPS23 is recognized as a driver of proliferation in luminal breast cancer. The aims of the present study were to describe MRPS23 copy number change in breast cancer, and to assess associations between MRPS23 copy ... -
mtDNA nt13708A Variant Increases the Risk of Multiple Sclerosis
(Peer reviewed; Journal article, 2008-02-13)Background: Mitochondrial DNA (mtDNA) polymorphism is a possible factor contributing to the maternal parent-of-origin effect in multiple sclerosis (MS) susceptibility. Methods and Findings: In order to investigate the role ... -
MtDNA sequence features associated with 'selfish genomes' predict tissue-specific segregation and reversion
(Journal article; Peer reviewed, 2020)Mitochondrial DNA (mtDNA) encodes cellular machinery vital for cell and organism survival. Mutations, genetic manipulation, and gene therapies may produce cells where different types of mtDNA coexist in admixed populations. ... -
MTHFD1 and relevant biomarkers in cardiovascular disease: Observational studies in patients with suspected stable angina pectoris in Norway
(Doctoral thesis, 2017-03-24)Background: As the leading cause of death globally, cardiovascular disease (CVD) is a major public health burden. Epidemiological and experimental studies consistently demonstrate an association between elevated total ... -
The mucinous domain of pancreatic carboxyl-ester lipase (CEL) contains core 1/core 2 O-glycans that can be modified by ABO blood group determinants
(Peer reviewed; Journal article, 2018)Carboxyl-ester lipase (CEL) is a pancreatic fat-digesting enzyme associated with human disease. Rare mutations in the CEL gene cause a syndrome of pancreatic exocrine and endocrine dysfunction denoted MODY8, whereas a ... -
Mulige interaksjoner mellom tyrosin kinase reseptoren Axl, metabolisme og proliferasjon i brystkreftceller (MDA-MB-231)
(Master thesis, 2009-05-19)Metabolismen i kreftceller er assosiert med økt aerob glykolyse, et fenomen omtalt som Warburg effekten. Den forhøyede glykolytiske raten utgjør en av de større forskjellene, som skiller normale celler fra kreftceller, og ... -
Multi-ancestry genome-wide association analyses improve resolution of genes and pathways influencing lung function and chronic obstructive pulmonary disease risk
(Journal article; Peer reviewed, 2023)Lung-function impairment underlies chronic obstructive pulmonary disease (COPD) and predicts mortality. In the largest multi-ancestry genome-wide association meta-analysis of lung function to date, comprising 580,869 ... -
A multi-layer perceptron network for perfusion parameter estimation in DCE-MRI studies of the healthy kidney
(Journal article; Peer reviewed, 2020)Background: Dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) is an imaging technique which helps in visualizing and quantifying perfusion—one of the most important indicators of an organ’s state. This paper ... -
Multi-Level Communication of Human Retinal Pigment Epithelial Cells via Tunneling Nanotubes
(Peer reviewed; Journal article, 2012-03-22)Background: Tunneling nanotubes (TNTs) may offer a very specific and effective way of intercellular communication. Here we investigated TNTs in the human retinal pigment epithelial (RPE) cell line ARPE-19. Morphology of ... -
Multi-national Gene Expression Profiling of Oral Squamous Cell Carcinomas. Biological Pathways Regardless of Differences Related to Life-style and Ethnicity
(Doctoral thesis, 2012-02-02)Oral squamous cell carcinoma (OSCC) is a major health problem in many developing countries, representing more than 25% of all new cancer cases in some countries such as India and Sri Lanka. Cigarette smoking, smokeless ... -
Multi-omics and machine learning for the prevention and management of female reproductive health
(Journal article; Peer reviewed, 2023)Females typically carry most of the burden of reproduction in mammals. In humans, this burden is exacerbated further, as the evolutionary advantage of a large and complex human brain came at a great cost of women’s ... -
Multi-psychotropic drug prescription and the association to neuropsychiatric symptoms in three Norwegian nursing home cohorts between 2004 and 2011
(Peer reviewed; Journal article, 2016-06-01)Background Neuropsychiatric symptoms, such as affective symptoms, psychosis, agitation, and apathy are common among nursing home patients with and without dementia. Treatment with one or more psychotropic drug is often ... -
Multi-Wavelength Photobiomodulation Therapy Combined with Static Magnetic Field on Long-Term Pulmonary Complication after COVID-19: A Case Report
(Journal article; Peer reviewed, 2021)Introduction: Photobiomodulation therapy, alone (PBMT) or combined with a static magnetic field (PBMT-sMF), has been demonstrated to be effective in the regeneration of tissues, modulation of inflammatory processes, and ... -
A multicenter study on Leigh syndrome: disease course and predictors of survival
(Peer reviewed; Journal article, 2014-04-15)Background: Leigh syndrome is a progressive neurodegenerative disorder, associated with primary or secondary dysfunction of the mitochondrial oxidative phosphorylation. Despite the fact that Leigh syndrome is the most ... -
A multicomponent intervention to optimise nurseepatient communication in the intensive care unit: A mixed-methods acceptability and feasibility study
(Journal article; Peer reviewed, 2021)Background Mechanically ventilated patients in intensive care units may experience communication challenges owing to intubation, which affects nurse–patient communication. Several strategies may optimise communication, ... -
The multidimensional fatigue inventory (MFI-20): psychometrical testing in a Norwegian sample of inflammatory bowel disease (IBD) patients
(Journal article; Peer reviewed, 2022)OBJECTIVES To evaluate the psychometric properties of the Norwegian version of the multidimensional fatigue inventory (MFI-20) in patients with inflammatory bowel disease. METHODS Participants were recruited from nine ... -
Multidimensional tracking of phenotypes and organ involvement in a complete nationwide systemic sclerosis cohort
(Journal article; Peer reviewed, 2020)Objective SSc is a severe, heterogeneous multi-organ disease where population-based estimates on phenotypic spectrum, overall disease burden and societal impact are largely missing. Here the objective was to provide the ... -
Multidimensjonal stratifisert behandling av uspesifikke korsryggsmerter: en systematisk oversikt
(Master thesis, 2016-10-31)Studiedesign: Systematic review. Background: Non-specific low back pain (NSLBP) is a heterogeneous condition that has proven difficult to treat. To increase treatment effects stratified care is regarded as a promising ... -
Multidisciplinary approaches to identifying and managing global airways disease: Expert recommendations based on qualitative discussions
(Journal article; Peer reviewed, 2023)Background: Chronic rhinosinusitis with nasal polyps (CRSwNP) and asthma frequently co-exist and share pathologic features. Taking a “global” treatment approach benefits diagnosis and treatment of both, but care is often ...