Blar i Faculty of Medicine på tittel
Viser treff 3245-3264 av 8868
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The first vanE-type vancomycin resistant Enterococcus faecalis isolates in Norway – phenotypic and molecular characteristics
(Journal article; Peer reviewed, 2023)Objectives We aimed to characterize the vanE cluster and its genetic support in the first Norwegian vanE-type isolates and assess genetic relatedness to other vanE isolates. Methods Two vanE-type vancomycin resistant ... -
A first-level customization study of SAPS II with Norwegian Intensive Care and Pandemic Registry (NIPaR) data
(Journal article; Peer reviewed, 2023)Background: Severity scores and mortality prediction models (MPMs) are important tools for benchmarking and stratification in the intensive care unit (ICU) and need to be regularly updated using data from a local and ... -
Fish oil and krill oil differentially modify the liver and brain lipidome when fed to mice
(Peer reviewed; Journal article, 2015-08-11)Background: Marine food is an important source of omega-3 fatty acids with beneficial health effects. Oils from marine organisms have different fatty acid composition and differ in their molecular composition. Fish oil ... -
Fish oil and krill oil supplementations differentially regulate lipid catabolic and synthetic pathways in mice
(Peer reviewed; Journal article, 2014-04-27)Background: Marine derived oils are rich in long-chain polyunsaturated omega-3 fatty acids, in particular eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), which have long been associated with health promoting ... -
A fish protein hydrolysate alters fatty acid composition in liver and adipose tissue and increases plasma carnitine levels in a mouse model of chronic inflammation
(Peer reviewed; Journal article, 2013-10-07)Background: There is growing evidence that fish protein hydrolysate (FPH) diets affect mitochondrial fatty acid metabolism in animals. The aim of the study was to determine if FPH could influence fatty acid metabolism and ... -
Fitness in fatness : Associations with cardiovascular risk factors and subclinical disease
(Doctoral thesis, 2019-05-24)Background: Fitness may influence cardiovascular (CV) health in obesity. We explored the impact of fitness on CV risk factors and prevalent subclinical CV disease in overweight and obese women and men without known CV ... -
Five Myths about the HIV Epidemic in Asia
(Peer reviewed; Journal article, 2006-10-03)It is widely recognised that the huge population sizes of many Asian countries mean that although national HIV prevalence levels are still very low, very large absolute numbers of people are being infected each year with ... -
Five salmon dinners per week were not sufficient to prevent the reduction in serum vitamin D in autumn at 60° north latitude: A randomised trial
(Journal article; Peer reviewed, 2020)Low serum concentrations of several vitamins have been linked to increased risk of diseases including insulin resistance and type 2 diabetes (T2D). Fish is a good source of several vitamins, and the prevalence of T2D is ... -
Five-year Changes in Health-Related Quality of Life after Biliopancreatic Diversion with Duodenal Switch
(Peer reviewed; Journal article, 2013-05-31)Background: Long-term data of health-related quality of life (HRQL) after biliopancreatic diversion with duodenal switch (BPDDS) procedure are lacking. The aim of this study was to evaluate changes in HRQL from baseline ... -
A five-year prospective study of fatigue in primary Sjögren’s syndrome
(Peer reviewed; Journal article, 2011-10-13)Introduction: Fatigue is prevalent in primary Sjögren’s syndrome (pSS), and contributes to the considerably reduced health related quality of life in this disease. The symptom is included in proposed disease activity and ... -
Fixation, sex, and age: highest risk of revision for uncemented stems in elderly women - data from 66,995 primary total hip arthroplasties in the Norwegian Arthroplasty Register
(Peer reviewed; Journal article, 2020)Background and purpose: There is no consensus on best method of fixation in hip arthroplasty. We investigated different modes of fixation in primary total hip arthroplasty (THA) and the influence of age and sex, to assess ... -
The flavagline FL3 interferes with the association of Annexin A2 with the eIF4F initiation complex and transiently stimulates the translation of annexin A2 mRNA
(Journal article; Peer reviewed, 2023-05-12)Introduction: Annexin A2 (AnxA2) plays a critical role in cell transformation, immune response, and resistance to cancer therapy. Besides functioning as a calcium- and lipidbinding protein, AnxA2 also acts as an mRNA-binding ... -
Flåttbårne infeksjoner og selvrapporterte helseplager; en helseundersøkelse i Søgne kommune, Sør-Norge
(Doctoral thesis, 2021-01-22)Background: Data on human exposure to tick-borne infections in Norway are scarce, and it is heavily debated whether tick-borne infections can cause chronic subjective health complaints. The main aims of this study were to ... -
A flexible formula for incorporating distributive concerns into cost-effectiveness analyses: Priority weights
(Peer reviewed; Journal article, 2019-10-10)Background Cost effectiveness analyses (CEAs) are widely used to evaluate the opportunity cost of health care investments. However, few functions that take equity concerns into account are available for such CEA methods, ... -
Flexible Players within the Sheaths: The Intrinsically Disordered Proteins of Myelin in Health and Disease
(Journal article; Peer reviewed, 2020)Myelin ensheathes selected axonal segments within the nervous system, resulting primarily in nerve impulse acceleration, as well as mechanical and trophic support for neurons. In the central and peripheral nervous systems, ... -
Flow cytometry based analyses as a tool in biomarker discovery for patient stratification in primary Sjögren’s syndrome
(Doctoral thesis, 2017-03-09)Primary Sjögren’s syndrome (pSS) is a systemic autoimmune disease characterized by lymphocytic infiltrates of exocrine glands, notably the salivary and lacrimal glands combined with immune-mediated glandular destruction. ... -
Flow cytometry-based functional selection of RNA interference triggers for efficient epi-allelic analysis of therapeutic targets
(Peer reviewed; Journal article, 2014-06-21)Background: The dose-response relationship is a fundamental pharmacological parameter necessary to determine therapeutic thresholds. Epi-allelic hypomorphic analysis using RNA interference (RNAi) can similarly correlate ... -
Flt3 receptor tyrosine kinase in AML and its modulation of the p53/Hdm2/Bcl-2 pathway
(Doctoral thesis, 2007-09-06)Acute myeloid leukemia (AML) is an aggressive disease with a poor overall survival rate. The most frequent mutations associated with AML are internal tandem duplications (ITD) in the juxtamembrane region of the receptor ... -
FLT3-ITD mutations in acute myeloid leukaemia – molecular characteristics, distribution and numerical variation
(Journal article; Peer reviewed, 2021)Recurrent somatic internal tandem duplications (ITD) in the FMS-like tyrosine kinase 3 (FLT3) gene characterise approximately one third of patients with acute myeloid leukaemia (AML), and FLT3-ITD mutation status guides ... -
Fluctuating biomarkers in primary sclerosing cholangitis: A longitudinal comparison of alkaline phosphatase, liver stiffness, and ELF
(Journal article; Peer reviewed, 2021)Background & Aims Primary sclerosing cholangitis (PSC) is a progressive liver disease characterised by fluctuating liver biochemistries and highly variable disease progression. The Enhanced Liver Fibrosis (ELF®) test and ...