Browsing Faculty of Medicine by Title
Now showing items 4682-4701 of 8872
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Intravenous Cyclophosphamide in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome. An Open-Label Phase II Study
(Journal article; Peer reviewed, 2020)Introduction: Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) is a disease with high symptom burden, of unknown etiology, with no established treatment. We observed patients with long-standing ME/CFS who got ... -
Intrinsic Differences in Spatiotemporal Organization and Stromal Cell Interactions Between Isogenic Lung Cancer Cells of Epithelial and Mesenchymal Phenotypes Revealed by High-Dimensional Single-Cell Analysis of Heterotypic 3D Spheroid Models
(Journal article; Peer reviewed, 2022)The lack of inadequate preclinical models remains a limitation for cancer drug development and is a primary contributor to anti-cancer drug failures in clinical trials. Heterotypic multicellular spheroids are three-dimensional ... -
Introducing debate as a pedagogical tool in pharmacy education
(Journal article; Peer reviewed, 2023)Communication skills are crucial for pharmacists’ role in counselling and providing information to patients, other healthcare practitioners, and the community. This study explores the implementation of debate as a pedagogical ... -
Introducing post-discharge malaria chemoprevention (PMC) for management of severe anemia in Malawian children: a qualitative study of community health workers’ perceptions and motivation
(Journal article; Peer reviewed, 2018-12-19)Severe malarial anaemia is one of the leading causes of paediatric hospital admissions in Malawi. Post-discharge malaria chemoprevention (PMC) is the intermittent administration of full treatment courses of antimalarial ... -
Introduction of aromatic ring-containing substituents in cyclic nucleotides is associated with inhibition of toxin uptake by the hepatocyte transporters OATP 1B1 and 1B3
(Peer reviewed; Journal article, 2014-04-16)Analogs of the cyclic nucleotides cAMP and cGMP have been extensively used to mimic or modulate cellular events mediated by protein kinase A (PKA), Exchange protein directly activated by cAMP (Epac), or protein kinase G ... -
Introduction of birth dose of hepatitis B virus vaccine to the immunization program in Ethiopia: An economic evaluation
(Journal article; Peer reviewed, 2020)Background Hepatitis B virus (HBV) infection is an important cause of morbidity and mortality with a very high burden in Africa. The risk of developing chronic infection is marked if the infection is acquired perinatally, ... -
Introduction of positron emission tomography into the Western Norwegian Health Region: Regional balance in resource utilization from 2009 to 2014
(Peer reviewed; Journal article, 2015)Background: The aim was to compare resource utilization across the four health trusts within the Western Norway Regional Health Authority since the establishment of positron emission tomography (PET) at Haukeland University ... -
Introduction to opportunities and pitfalls in functional mass spectrometry based proteomics
(Peer reviewed; Journal article, 2014-01)With the advent of mass spectrometry based proteomics, the identification of thousands of proteins has become commonplace in biology nowadays. Increasingly, efforts have also been invested toward the detection and localization ... -
The intronic BRCA1 c.5407-25T>A variant causing partly skipping of exon 23—a likely pathogenic variant with reduced penetrance?
(Peer reviewed; Journal article, 2020-03-20)Rare sequence variants in the non-coding part of the BRCA genes are often reported as variants of uncertain significance (VUS), which leave patients and doctors in a challenging position. The aim of this study was to ... -
The Inverse Association of Body Mass Index with Lung Cancer: Exploring Residual Confounding, Metabolic Aberrations and Within-Person Variability in Smoking
(Journal article; Peer reviewed, 2021)Background: The inverse observational association between body mass index (BMI) and lung cancer risk remains unclear. We assessed whether the association is explained by metabolic aberrations, residual confounding, and ... -
Inverse correlation between PDGFC expression and lymphocyte infiltration in human papillary thyroid carcinoma
(Peer reviewed; Journal article, 2009-12-08)Background: Members of the PDGF family have been suggested as potential biomarkers for papillary thyroid carcinomas (PTC). However, it is known that both expression and stimulatory effect of PDGF ligands can be affected ... -
Investigating novel biomarkers of immune activation and modulation in the context of sedentary behaviour: a multicentre prospective ischemic stroke cohort study
(Journal article; Peer reviewed, 2021)Background Sedentary behaviour is associated with disease, but the molecular mechanisms are not understood. Valid biomarkers with predictive and explanatory properties are required. Therefore, we have investigated traditional ... -
Investigating Shared Genetic Basis Across Tourette Syndrome and Comorbid Neurodevelopmental Disorders Along the Impulsivity-Compulsivity Spectrum
(Journal article; Peer reviewed, 2021)Background Tourette syndrome (TS) is often found comorbid with other neurodevelopmental disorders across the impulsivity-compulsivity spectrum, with attention-deficit/hyperactivity disorder (ADHD), autism spectrum disorder ... -
Investigating The Healthiness of Online Recipes in Norway Compared to the UK and the US
(Master thesis, 2022-12-15) -
Investigating the human jejunal microbiota
(Journal article; Peer reviewed, 2022)Descriptions of the small intestinal microbiota are deficient and conflicting. We aimed to get a reliable description of the jejunal bacterial microbiota by investigating samples from two separate jejunal segments collected ... -
Investigating the human small intestinal microbiota : Microbiological characterization of jejunal and ileal samples collected during surgery
(Doctoral thesis, 2022-10-25)Kartlegging av tynntarmsmikrobiota hos mennesker : Mikrobiologisk beskrivelse av kirurgiske prøver fra jejunum og ileum Beskrivelser av tynntarmsmikrobiota (tarmflora) i lærebøker og vitenskapelige artikler er lite ... -
Investigating the rationale for COPD maintenance therapy prescription across Europe, findings from a multi-country study
(Journal article; Peer reviewed, 2023)This study aims to understand healthcare professionals’ thoughts and motivations about optimal management and treatment of patients with chronic obstructive pulmonary disease (COPD). We conducted a DELPHI survey through ... -
Investigating the relationship between allocentric spatial working memory and biomarker status in preclinical and prodromal Alzheimer’s disease
(Journal article; Peer reviewed, 2023)The 4 Mountain Test (4MT) is a test of allocentric spatial working memory and has been proposed as an earlier marker of predementia Alzheimer’s disease (AD) than episodic verbal memory. We here compare the 4MT to the CERAD ... -
Investigating the role of vitamin K in Axl-mediated melanoma progression and chemotherapeutic resistance
(Master thesis, 2018-06-29)Metastatic melanoma is a highly aggressive cancer with a very poor prognosis and current therapies remain inadequate. Norway is among the top five countries with the highest incidence of melanoma. Malignant cells carry ... -
Investigating the use of patient involvement and patient experience in quality improvement in Norway: rhetoric or reality?
(Peer reviewed; Journal article, 2013-06-06)Background: Patient involvement in health care decision making is part of a wider trend towards a more bottomup approach to service planning and provision, and patient experience is increasingly conceptualized as a core ...