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Limited association between infections, autoimmune disease and genetic risk and immune activation in severe mental disorders
(Journal article; Peer reviewed, 2022)Background Low-grade inflammation may be part of the underlying mechanism of schizophrenia and bipolar disorder. We investigated if genetic susceptibility, infections or autoimmunity could explain the immune activation. ... -
Limited Benefit of Fish Consumption on Risk of Hip Fracture among Men in the Community-Based Hordaland Health Study
(Peer reviewed; Journal article, 2018-07-06)Hip fractures have a high prevalence worldwide. Few studies have investigated whether fish consumption is associated with risk of hip fractures. The objective of the present study was to investigate the effect of fish ... -
Limited clinical efficacy of azacitidine in transfusion-dependent, growth factor-resistant, low- and Int-1-risk MDS: Results from the nordic NMDSG08A phase II trial
(Peer reviewed; Journal article, 2014)This prospective phase II study evaluated the efficacy of azacitidine (Aza)+erythropoietin (Epo) in transfusion-dependent patients with lower-risk myelodysplastic syndrome (MDS). Patients ineligible for or refractory to ... -
Limited cross-border infections in patients newly diagnosed with HIV in Europe
(Peer reviewed; Journal article, 2013-04-03)Background: International travel plays a role in the spread of HIV-1 across Europe. It is, however, not known whether international travel is more important for spread of the epidemic as compared to endogenous infections ... -
Limited Genetic Overlap Between Overt Hashimoto's Thyroiditis and Graves' Disease in Twins: A Population-based Study
(Journal article; Peer reviewed, 2021)Context Hashimoto’s thyroiditis (HT) and Graves’ disease (GD) are known to coaggregate in families, but the magnitude and nature of a shared etiology is unknown. Objectives To estimate the shared genetic influence on ... -
Linear age-course effects on the associations between body mass index, triglycerides, and female breast and male liver cancer risk: An internal replication study of 800,000 individuals
(Peer reviewed; Journal article, 2020)Apart from the consistently observed differential association between obesity and breast cancer risk by menopausal status, the associations between obesity and other metabolic imbalances with risks of cancers have not been ... -
Linear and non-linear analyses of Conner’s Continuous Performance Test-II discriminate adult patients with attention deficit hyperactivity disorder from patients with mood and anxiety disorders
(Peer reviewed; Journal article, 2016-08-11)Background: Attention Deficit Hyperactivity Disorder (ADHD) is a heterogeneous disorder. Therefore it is important to look for factors that can contribute to better diagnosis and classification of these patients. The aims ... -
Linear Growth Trajectories, Catch-up Growth, and Its Predictors Among North Indian Small-for-Gestational Age Low Birthweight Infants: A Secondary Data Analysis
(Journal article; Peer reviewed, 2022)Background: Low birthweight small-for-gestational-age (SGA-LBW) (birthweight below the 10th percentile for gestational age; SGA-LBW) infants are at an increased risk of poor postnatal growth outcomes. Linear growth ... -
The link between periodontal disease and rheumatoid arthritis: An updated review
(Peer reviewed; Journal article, 2014-01)Porphyromonas gingivalis is a leading pathogen in chronic periodontitis, a disease process involving progressive destruction of the tissues that support the teeth. Recently, the organism has been reported to produce a ... -
The link between wound healing and escape from tumor dormancy
(Peer reviewed; Journal article, 2019)Tumor dormancy is considered one of the major unsolved questions in cancer biology. Understanding the mechanisms responsible for maintaining and interrupting dormancy would be a major step towards preventing overt metastatic ... -
Linking a European cohort of children born with congenital anomalies to vital statistics and mortality records: A EUROlinkCAT study
(Journal article; Peer reviewed, 2021)EUROCAT is a European network of population-based congenital anomaly (CA) registries. Twenty-one registries agreed to participate in the EUROlinkCAT study to determine if reliable information on the survival of children ... -
Lipid effects during antipsychotic drug treatment and their relevance for clinical outcomes
(Doctoral thesis, 2020-01-29)Schizophrenia is a devastating mental disorder with disease mechanisms that are still poorly understood. Evidence has emerged that lipid dysregulations and myelination abnormalities might contribute to the pathophysiology ... -
Lipid levels after childbirth and association with number of children: A population-based cohort study
(Peer reviewed; Journal article, 2019-10-24)Objective Low parity women are at increased risk of cardiovascular mortality. Unfavourable lipid profiles have been found in one-child mothers years before they conceive. However, it remains unclear whether unfavourable ... -
Lipid parameters and vitamin A modify cardiovascular risk prediction by plasma neopterin
(Journal article; Peer reviewed, 2020)Objectives Oxidised cholesterol metabolites are linked to increased production of the active vitamin A (Vit-A) form and monocyte/macrophage activation, which may be reflected by neopterin, a marker of both interferon-γ–mediated ... -
Lipid, fatty acid, carnitine- and choline derivative profiles in rheumatoid arthritis outpatients with different degrees of periodontal inflammation
(Journal article; Peer reviewed, 2021)Rheumatoid arthritis (RA) and periodontitis are chronic inflammatory diseases with several pathogenic pathways in common. Evidence supports an association between the diseases, but the exact underlying mechanisms behind ... -
Lipid-Lowering Effects of Tetradecylthioacetic Acid in Antipsychotic-Exposed, Female Rats: Challenges with Long-Term Treatment
(Peer reviewed; Journal article, 2012-11-30)Background: Psychiatric patients often require chronic treatment with antipsychotic drugs, and while rats are frequently used to study antipsychotic-induced metabolic adverse effects, long-term exposure has only partially ... -
Lipocalin 2 expression is associated with aggressive features of endometrial cancer
(Peer reviewed; Journal article, 2012-05-06)Background: Increased expression of lipocalin 2 (LCN2) has been observed in several cancers. The aim of the present study was to investigate LCN2 in endometrial cancer in relation to clinico-pathologic phenotype, angiogenesis, ... -
LipoClear og ultrasentrifugering som metode for fjerning av lipoprotein i serum
(Master thesis, 2021-05-15)Bakgrunn: Hensikten med studien var å sammenligne LipoClear og ultrasentrifugering som metoder for å fjerne lipoproteiner i serum i pasientprøver med sterk lipemisk interferens for 10 biokjemiske analytter. Materiale og ... -
Lipogenic effects of antipsychotic drugs in cultured cells and in rat
(Doctoral thesis, 2007-05-10)The etiology of the serious psychiatric disorder schizophrenia is unknown. Epidemiological studies indicate a high heritability with a complex pattern of transmission. Moreover, structural and genetic findings indicate ... -
Lipopolysaccharide induces filtrate leakage from renal tubular lumina into the interstitial space via a proximal tubular Toll-like receptor 4–dependent pathway and limits sensitivity to fluid therapy in mice
(Journal article; Peer reviewed, 2019-12-16)Sustained oliguria during fluid resuscitation represents a perplexing problem in patients undergoing therapy for septic acute kidney injury. Here, we tested whether lipopolysaccharide induces filtrate leakage from the ...