Blar i Faculty of Medicine på tittel
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Lipid parameters and vitamin A modify cardiovascular risk prediction by plasma neopterin
(Journal article; Peer reviewed, 2020)Objectives Oxidised cholesterol metabolites are linked to increased production of the active vitamin A (Vit-A) form and monocyte/macrophage activation, which may be reflected by neopterin, a marker of both interferon-γ–mediated ... -
Lipid, fatty acid, carnitine- and choline derivative profiles in rheumatoid arthritis outpatients with different degrees of periodontal inflammation
(Journal article; Peer reviewed, 2021)Rheumatoid arthritis (RA) and periodontitis are chronic inflammatory diseases with several pathogenic pathways in common. Evidence supports an association between the diseases, but the exact underlying mechanisms behind ... -
Lipid-Lowering Effects of Tetradecylthioacetic Acid in Antipsychotic-Exposed, Female Rats: Challenges with Long-Term Treatment
(Peer reviewed; Journal article, 2012-11-30)Background: Psychiatric patients often require chronic treatment with antipsychotic drugs, and while rats are frequently used to study antipsychotic-induced metabolic adverse effects, long-term exposure has only partially ... -
Lipocalin 2 expression is associated with aggressive features of endometrial cancer
(Peer reviewed; Journal article, 2012-05-06)Background: Increased expression of lipocalin 2 (LCN2) has been observed in several cancers. The aim of the present study was to investigate LCN2 in endometrial cancer in relation to clinico-pathologic phenotype, angiogenesis, ... -
LipoClear og ultrasentrifugering som metode for fjerning av lipoprotein i serum
(Master thesis, 2021-05-15)Bakgrunn: Hensikten med studien var å sammenligne LipoClear og ultrasentrifugering som metoder for å fjerne lipoproteiner i serum i pasientprøver med sterk lipemisk interferens for 10 biokjemiske analytter. Materiale og ... -
Lipogenic effects of antipsychotic drugs in cultured cells and in rat
(Doctoral thesis, 2007-05-10)The etiology of the serious psychiatric disorder schizophrenia is unknown. Epidemiological studies indicate a high heritability with a complex pattern of transmission. Moreover, structural and genetic findings indicate ... -
Lipopolysaccharide induces filtrate leakage from renal tubular lumina into the interstitial space via a proximal tubular Toll-like receptor 4–dependent pathway and limits sensitivity to fluid therapy in mice
(Journal article; Peer reviewed, 2019-12-16)Sustained oliguria during fluid resuscitation represents a perplexing problem in patients undergoing therapy for septic acute kidney injury. Here, we tested whether lipopolysaccharide induces filtrate leakage from the ... -
Liposomal formulation of an emetine analog in combination with daunorubicin for the treatment of acute myeloid leukemia
(Master thesis, 2019-07-02) -
A liposomal formulation of simvastatin and doxorubicin for improved cardioprotective and anti-cancer effect
(Journal article; Peer reviewed, 2022)Anthracyclines such as doxorubicin (Dox) are the preferred chemotherapeutics for several cancers. However, Dox-induced cardiotoxicity limits its therapeutic potential. Liposomal encapsulation of Dox has been used for ... -
Liquid Biopsies in Solid Cancers: Implementation in a Nordic Healthcare System
(Journal article; Peer reviewed, 2021)Liquid biopsies have emerged as a potential new diagnostic tool, providing detailed information relevant for characterization and treatment of solid cancers. We here present an overview of current evidence supporting the ... -
Liquid biopsy-based protein biomarkers for risk prediction, early diagnosis, and prognostication of cholangiocarcinoma
(Journal article; Peer reviewed, 2023)Background & Aims Cholangiocarcinoma (CCA), heterogeneous biliary tumours with dismal prognosis, lacks accurate early diagnostic methods especially important for individuals at high-risk (i.e. those with primary sclerosing ... -
Listening to health workers: lessons from Eastern Uganda for strengthening the programme for the prevention of mother-to-child transmission of HIV
(Peer reviewed; Journal article, 2012-01-05)Background: The implementation and utilization of programmes for the prevention of mother-to-child transmission (PMTCT) of HIV in most low income countries has been described as sub-optimal. As planners and service providers, ... -
Listening to the polar oceans : Monitoring and mapping marine ecosystems using passive and active acoustics
(Doctoral thesis, 2020-06-12)This interdisciplinary thesis uses active and passive acoustics to study the polar marine ecosystems. The polar oceans are some of the most remote, harshest and least well studied environments of the planet, and also the ... -
Lithium increases mitochondrial respiration in iPSC-derived neural precursor cells from lithium responders
(Journal article; Peer reviewed, 2021)Lithium (Li), valproate (VPA) and lamotrigine (LTG) are commonly used to treat bipolar disorder (BD). While their clinical efficacy is well established, the mechanisms of action at the molecular level are still incompletely ... -
Litteraturstudie: Implantatbehandling på pasienter med ektodermal dysplasi
(Master thesis, 2022-01-31)Hensikt: Ektodermal dysplasi (ED) er en sjelden tilstand som kan føre til anomalier i strukturer av ektodermalt opphav, derunder tenner. Tilstanden kan også føre til funksjonelle og psykologiske problemer, og redusert ... -
Live Attenuated Influenza Vaccine (LAIV) Immunization in Children and Adults: Lesson for Development of Universal Influenza Vaccine
(Doctoral thesis, 2019-11-06)According to the WHO (World Health Organization), one billion peoples are infected annually of whom three to five millions become severely ill and 250-500 000 deaths worldwide (He, Wang et al. 2013) although the latest ... -
Live attenuated influenza vaccine in children induces b-cell responses in tonsils
(Peer reviewed; Journal article, 2016)Background. Tonsils play a key role in eliciting immune responses against respiratory pathogens. Little is known about how tonsils contribute to the local immune response after intranasal vaccination. Here, we uniquely ... -
Live well, die well - an international cohort study on experiences, concerns and preferences of patients in the last phase of life: the research protocol of the iLIVE study
(Journal article; Peer reviewed, 2022)Introduction Adequately addressing the needs of patients at the end of life and their relatives is pivotal in preventing unnecessary suffering and optimising their quality of life. The purpose of the iLIVE study is to ... -
Live-attenuated influenza vaccine induces tonsillar follicular T helper cell responses that correlate with antibody induction
(Journal article; Peer reviewed, 2020)Background: Influenza remains a major threat to public health. Live-attenuated influenza vaccines (LAIV) have been shown to be effective, particularly in children. Follicular T helper (TFH) cells provide B-cell help and ... -
LIVE@Home.Path--innovating the clinical pathway for home-dwelling people with dementia and their caregivers: Study protocol for a mixed-method, stepped-wedge, randomized controlled trial
(Journal article; Peer reviewed, 2020)Background The global health challenge of dementia is exceptional in size, cost and impact. It is the only top ten cause of death that cannot be prevented, cured or substantially slowed, leaving disease management, caregiver ...