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Looking forward to the next 15 years: innovation and new pathways for research in health equity
(Peer reviewed; Journal article, 2017)Since our launch in 2002, the International Journal for Equity in Health (IJEqH) has furthered our collective understanding of equity in health and health services by providing a platform on which academics and practitioners ... -
Lopinavir/Ritonavir versus Lamivudine peri-exposure prophylaxis to prevent HIV-1 transmission by breastfeeding: the PROMISE-PEP trial Protocol ANRS 12174
(Peer reviewed; Journal article, 2012-10-06)Background: Postnatal transmission of HIV-1 through breast milk remains an unsolved challenge in many resource-poor settings where replacement feeding is not a safe alternative. WHO now recommends breastfeeding of infants ... -
Loss of COPZ1 induces NCOA4 mediated autophagy and ferroptosis in glioblastoma cell lines
(Journal article; Peer reviewed, 2021)Dysregulated iron metabolism is a hallmark of many cancers, including glioblastoma (GBM). However, its role in tumor progression remains unclear. Herein, we identified coatomer protein complex subunit zeta 1 (COPZ1) as a ... -
Loss of epigenetic suppression of retrotransposons with oncogenic potential in aging mammary luminal epithelial cells
(Journal article; Peer reviewed, 2023)A primary function of DNA methylation in mammalian genomes is to repress transposable elements (TEs). The widespread methylation loss that is commonly observed in cancer cells results in the loss of epigenetic repression ... -
Loss of health certificates among offshore petroleum workers on the Norwegian Continental Shelf 2002-2010
(Peer reviewed; Journal article, 2011)Background: A health certificate is required to work on the offshore petroleum installations of the Norwegian Shelf. Loss of health certificate (“loss of licence”, LOL) may cause economic problems for the individual worker. ... -
Loss of life years due to unavailable helicopter emergency medical service: a single base study from a rural area of Norway
(Peer reviewed; Journal article, 2019)Background: Despite the potential benefits of physician-staffed Helicopter Emergency Medical Service (HEMS), many dispatches to primary HEMS missions in Norway are cancelled before patient encounter. Information is sparse ... -
Loss of N-terminal acetyltransferase A activity induces thermally unstable ribosomal proteins and increases their turnover in Saccharomyces cerevisiae
(Journal article; Peer reviewed, 2023)Protein N-terminal (Nt) acetylation is one of the most abundant modifications in eukaryotes, covering ~50-80 % of the proteome, depending on species. Cells with defective Nt-acetylation display a wide array of phenotypes ... -
Loss of S100A14 expression at the tumor-invading front correlates with poor differentiation and worse prognosis in oral squamous cell carcinoma
(Journal article; Peer reviewed, 2020)Background We previously showed a tumor‐suppressive function of S100A14 in oral squamous cell carcinoma (OSCC). This study aimed to examine the prognostic significance and differentiation‐related function of S100A14 in ... -
Loss or mislocalization of aquaporin-4 affects diffusion properties and intermediary metabolism in gray matter of mice
(Peer reviewed; Journal article, 2017-01)The first aim of this study was to determine how complete or perivascular loss of aquaporin-4 (AQP4) water channels affects membrane permeability for water in the mouse brain grey matter in the steady state. Time-dependent ... -
Loss to follow-up pattern in TB patients in Rawalpindi, Pakistan
(Peer reviewed; Journal article, 2015)Background: Tuberculosis is a serious global public health, social and economical problem that affects millions of people particularly in low income countries. The aim of this study was to see the loss to follow up pattern ... -
Loss-of-function variants in the schizophrenia risk gene SETD1A alter neuronal network activity in human neurons through the cAMP/PKA pathway
(Journal article; Peer reviewed, 2022)Heterozygous loss-of-function (LoF) mutations in SETD1A, which encodes a subunit of histone H3 lysine 4 methyltransferase, cause a neurodevelopmental syndrome and increase the risk for schizophrenia. Using CRISPR-Cas9, we ... -
Lost opportunities in HIV prevention: programmes miss places where exposures are highest
(Peer reviewed; Journal article, 2008-01-24)Background: Efforts at HIV prevention that focus on high risk places might be more effective and less stigmatizing than those targeting high risk groups. The objective of the present study was to assess risk behaviour ... -
Low 25-hydroxyvitamin D2 and 25-hydroxyvitamin D3 levels are independently associated with macroalbuminuria, but not with retinopathy and macrovascular disease in type 1 diabetes: the EURODIAB prospective complications study
(Peer reviewed; Journal article, 2015-05-30)Background Low circulating levels of total vitamin D [25(OH)D] and 25(OH)D3 have been associated with vascular complications in few studies on individuals with type 1 diabetes. However, these measures are affected by UV ... -
Low adherence to exclusive breastfeeding in Eastern Uganda: A community-based cross-sectional study comparing dietary recall since birth with 24-hour recall
(Peer reviewed; Journal article, 2007-03-01)Background: Exclusive breastfeeding is recommended as the best feeding alternative for infants up to six months and has a protective effect against mortality and morbidity. It also seems to lower HIV-1 transmission compared ... -
The Low Affinity Nerve Growth Factor Receptor p75NTR Identifies a Transient Stem Cell-Like State in Oral Squamous Cell Carcinoma Cells
(Peer reviewed; Journal article, 2014-09-12)Background Although several markers have been used for enrichment of cells with stem cell-like properties in oral squamous cell carcinoma (OSCC), isolation of a pure subpopulation is still a challenging task. Normal oral ... -
Low and unequal use of outpatient health services in public primary health care facilities in southern Ethiopia: a facility-based cross-sectional study
(Journal article; Peer reviewed, 2021)Background: Outpatient department visits per individual for each year are one of the core indicators of healthcare delivery to assess accessibility or quality of services. In addition, this study aimed to assess health ... -
Low birth weight and risk of progression to end stage renal disease in IgA nephropathy - A retrospective registry-based cohort study
(Peer reviewed; Journal article, 2016-04-19)Background: Low Birth Weight (LBW) is a surrogate for fetal undernutrition and is associated with impaired nephron development in utero. In this study, we investigate whether having been born LBW and/or small for gestational ... -
Low birth weight and risk of progressive kidney disease. Epidemiological and morphological studies
(Doctoral thesis, 2016-10-19)Background: Low Birth Weight (LBW) and Small for Gestation Age (SGA) are surrogate markers for fetal undernutrition and are associated with impaired nephron development in utero as suggested by the Brenner`s hypothesis. ... -
Low birth weight, intrauterine growth restriction and risk of chronic kidney disease in adult age
(Doctoral thesis, 2022-06-16)Background and aims: Studies have shown that adults with low birth weight (LBW) face an increased risk for chronic kidney disease (CKD), high blood pressure and cardiovascular disease (CVD). Previous Norwegian studies have ... -
Low birthweight is associated with lower glomerular filtration rate in middle-aged mainly healthy women
(Journal article; Peer reviewed, 2020)Background Low birthweight (LBW) has been shown to increase the risk of severe kidney disease. Studies have also shown associations between LBW and lower estimated glomerular filtration rate (GFR) in young adults. In this ...