Blar i Faculty of Medicine på tittel
Viser treff 5496-5515 av 8847
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Molecular structure and function of myelin protein P0 in membrane stacking
(Peer reviewed; Journal article, 2019)Compact myelin forms the basis of nerve insulation essential for higher vertebrates. Dozens of myelin membrane bilayers undergo tight stacking, and in the peripheral nervous system, this is partially enabled by myelin ... -
Molecular subtypes in stage II-III colon cancer defined by genomic instability: Early recurrence-risk associated with a high copy-number variation and loss of RUNX3 and CDKN2A
(Peer reviewed; Journal article, 2015-04-16)Objective: We sought to investigate various molecular subtypes defined by genomic instability that may be related to early death and recurrence in colon cancer. Methods: We sought to investigate various molecular subtypes ... -
Molecular Subtypes of Breast Cancer: Long-term Incidence Trends and Prognostic Differences
(Peer reviewed; Journal article, 2016-12)Background: Secular trends in incidence and prognosis of molecular breast cancer subtypes are poorly described. We studied long-term trends in a population of Norwegian women born 1886–1977. Methods: A total of 52,949 women ... -
Molecular subtypes, histopathological grade and survival in a historic cohort of breast cancer patients
(Peer reviewed; Journal article, 2013-08)Molecular subtyping of breast cancer may provide additional prognostic information regarding patient outcome. However, its clinical significance remains to be established. In this study, the main aims were to discover ... -
Monitoring activities in out-of-hours emergency primary care in Norway. A special emphasis on nurses telephone triage and counselling
(Doctoral thesis, 2011-11-18)The main aim of this thesis has been to develop and establish an organisation, the Watchtowers, in order to continuously collect valid data from the OOH services in Norway, and to describe the activities. Further, we have ... -
Monitoring children and adolescents with severe obesity: body mass index (BMI), BMI z‐score or percentage above the International Obesity Task Force overweight cut‐off?
(Peer reviewed; Journal article, 2019)Aim: Body mass index (BMI) metrics are widely used as a proxy for adiposity in children with severe obesity. The BMI expressed as the percentage of a cut‐off percentile for overweight or obesity has been proposed as a ... -
Monitoring multiple myeloma by quantification of recurrent mutations in serum
(Peer reviewed; Journal article, 2017)Circulating tumor DNA is a promising biomarker to monitor tumor load and genome alterations. We explored the presence of circulating tumor DNA in multiple myeloma patients and its relation to disease activity during long-term ... -
Monoamine synthesis in neurometabolic disorders affecting catecholaminergic functioning: biochemical mechanisms and treatment implications
(Doctoral thesis, 2024-02-14)Løpet av de siste 100 år er det oppdaget hundrevis av arvelige metabolske forstyrrelser. Slike tilstander har ofte recessiv Mendelsk arv og kalles også medfødte metabolismefeil. Symptomene debuterer vanligvis like etter ... -
The monocyte system in haematological malignancies
(Doctoral thesis, 2020-04-17)Monocytes consist of classical, intermediate, and non-classical monocytes. In haematological malignancies, such as multiple myeloma and acute myeloid leukaemia, monocytes are affected by both the disease itself and the ... -
Monocyte-derived dendritic cells in cancer immunotherapy : Considerations on their applicability
(Doctoral thesis, 2021-02-17)Cancer is the leading cause of death in the developed world. While treatment options and detection have improved over the last century, mortality rate remains high especially in metastatic disease. Traditional treatment ... -
Monocytes from neonates and adults have a similar capacity to adapt their cytokine production after previous exposure to BCG and β-glucan
(Journal article; Peer reviewed, 2020-02-21)The Bacillus Calmette-Guérin (BCG) vaccine is administered at birth in tuberculosis (TB) endemic countries. BCG vaccination is also associated with protective non-specific effects against non-tuberculous infections. This ... -
Monogenic diabetes and pancreatic exocrine dysfunction in mouse and man
(Doctoral thesis, 2009-12-04)Exocrine and endocrine pancreatic disease is often observed to occur together. The close colocalization of the endocrine and exocrine tissues within one organ, as well as their common embryological ancestry, have given ... -
Monolithic zirconia crowns in the aesthetic zone in heavy grinders with severe tooth wear – An observational case-series
(Peer reviewed; Journal article, 2018)Objectives The aim of this study was to assess the clinical outcomes and patient satisfaction with monolithic zirconia crowns in patients with severe tooth wear (≥1/3 of the tooth crown) in the aesthetic zone. Methods The ... -
Monolithic zirconia crowns – wall thickness, surface treatment and load at fracture
(Peer reviewed; Journal article, 2019)Purpose: The aim of this study was to evaluate the effect of wall thickness on load at fracture of monolithic zirconia dental crowns after aging. Materials and Methods: Seventy translucent monolithic zirconia crowns (DD ... -
Monte Carlo vs. Pencil Beam based optimization of stereotactic lung IMRT
(Peer reviewed; Journal article, 2009-12-12)Background: The purpose of the present study is to compare finite size pencil beam (fsPB) and Monte Carlo (MC) based optimization of lung intensity-modulated stereotactic radiotherapy (lung IMSRT). Materials and methods: ... -
Month of birth and risk of multiple sclerosis: confoundingand adjustments
(Peer reviewed; Journal article, 2014-02)A month of birth effect on multiple sclerosis (MS) risk has been reported from different countries. Recent critics have suggested that this finding is caused by confounding and that adequately adjusting for year and place ... -
Monthly variations in self-report of time-specified and typical alcohol use: The Nord-Trøndelag Health Study (HUNT3)
(Peer reviewed; Journal article, 2015-02-21)Background Aggregated measures are often employed when prevalence, risk factors and consequences of alcohol use in the population are monitored. In order to avoid time-dependent bias in aggregated measures, reference periods ... -
Moral distress - a threat to dementia care? A qualitative study of nursing staff members’ experiences in long-term care facilities
(Journal article; Peer reviewed, 2022)Background Dementia is a public health priority worldwide due to its rapidly increasing prevalence and poses challenges with regard to providing proper care, including end-of-life care. This study is part of a research ... -
Morbidity and Mortality after Emergency and Urgent Colorectal Surgery for Malignant and Benign Disease
(Peer reviewed; Journal article, 2009)Abstract: Aim: The aim of this study was to determine short and long-term morbidity and mortality rates after emergency colorectal surgery for benign and malignant disease in a high volume tertiary referral hospital in ... -
More support for mothers: a qualitative study on factors affecting immunisation behaviour in Kampala, Uganda
(Peer reviewed; Journal article, 2011-09-25)Background: The proportion of Ugandan children who are fully vaccinated has varied over the years. Understanding vaccination behaviour is important for the success of the immunisation programme. This study examined influences ...