Blar i Faculty of Medicine på tittel

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    • Cancer and stroke: commonly encountered by clinicians, but little evidence to guide clinical approach 

      Woock, Malin; Martinez-Majander, Nicolas; Seiffge, David J.; Selvik, Henriette Aurora; Nordanstig, Annika; Redfors, Petra; Lindgren, Erik; Sanchez van Kammen, Mayte; Rentzos, Alexandros; Coutinho, Jonathan M.; Doyle, Karen; Næss, Halvor; Putaala, Jukka; Jood, Katarina; Tatlisumak, Turgut (Journal article; Peer reviewed, 2022)
      The association between stroke and cancer is well-established. Because of an aging population and longer survival rates, the frequency of synchronous stroke and cancer will become even more common. Different pathophysiologic ...

    • Cancer and Total Hip Replacement. Cancer as a risk factor for prosthesis and prosthesis as a risk factor for cancer 

      Dybvik, Eva Hansen (Doctoral thesis, 2015-09-18)
      Annually, 14 million new cancer cases are detected worldwide; the numbers are expected to rise by 70% over the next decades. In Norway, 30,000 new cancer cases are detected every year. Because of screenings and increased ...

    • Cancer awareness in the general population varies with sex, age and media coverage: A population-based survey with focus on gynecologic cancers 

      Fonnes, Tina; Telle, Ingrid Ovidia Moe; Forsse, David Erik; Falck, Runa; Trovik, Jone; Haldorsen, Ingfrid S.; Krakstad, Camilla (Journal article; Peer reviewed, 2021)
      Objectives There is a need for more knowledge about the public awareness and attitudes towards gynecologic cancers. We employed a research-purpose population-based citizen panel to assess how often people recall gynecologic ...

    • Cancer cachexia associates with a systemic autophagy-inducing activity mimicked by cancer cell-derived IL-6 trans-signaling 

      Pettersen, Kristine; Andersen, Sonja Benedikte; Degen, simone; Tadini, Valentina; Grosjean, Joel; Hatakeyama, Shinji; Tesfahun, Almaz Nigatu; Moestue, Siver Andreas; Kim, Jana; Nonstad, Unni; Romundstad, Pål Richard; Skorpen, Frank; Sørhaug, Sveinung; Amundsen, Tore; Grønberg, Bjørn Henning; Strasser, Florian; Stephens, Nathan; Hoem, Dag; Molven, Anders; Kaasa, Stein; Fearon, Kenneth; Jacobi, Carsten; Bjørkøy, Geir (Peer reviewed; Journal article, 2017-05-17)
      The majority of cancer patients with advanced disease experience weight loss, including loss of lean body mass. Severe weight loss is characteristic for cancer cachexia, a condition that significantly impairs functional ...

    • Cancer cell heterogeneity and plasticity: A paradigm shift in glioblastoma 

      Yabo, Yahaya A.; Niclou, Simone Pierrette; Golebiewska, Anna (Journal article; Peer reviewed, 2022)
      Phenotypic plasticity has emerged as a major contributor to intra-tumoral heterogeneity and treatment resistance in cancer. Increasing evidence shows that glioblastoma (GBM) cells display prominent intrinsic plasticity and ...

    • Cancer cell line-specific protein profiles in extracellular vesicles identified by proteomics 

      Mazagão Guerreiro, Eduarda; Øvstebø, Reidun; Thiede, Bernd; Costea, Daniela Elena; Søland, Tine Merete; Galtung, Hilde (Journal article; Peer reviewed, 2020-09-04)
      Extracellular vesicles (EVs), are important for intercellular communication in both physiological and pathological processes. To explore the potential of cancer derived EVs as disease biomarkers for diagnosis, monitoring, ...

    • Cancer epigenetics in solid organ tumours: A primer for surgical oncologists 

      Drake, Thomas M.; Søreide, Kjetil (Peer reviewed; Journal article, 2019-05)
      Cancer is initiated through both genetic and epigenetic alterations. The end-effect of such changes to the DNA machinery is a set of uncontrolled mechanisms of cell division, invasion and, eventually, metastasis. Epigenetic ...

    • Cancer in ANCA-Associated Glomerulonephritis: A Registry-Based Cohort Study 

      Sriskandarajah, Sanjeevan; Bostad, Leif; Myklebust, Tor Åge; Møller, Bjørn; Skrede, Steinar; Bjørneklett, Rune (Peer reviewed; Journal article, 2017-12-18)
      Background. Immunosuppressive therapy for antineutrophil cytoplasmic antibody-associated vasculitis has been associated with increased malignancy risk. Objectives. To quantify the cancer risk associated with contemporary ...

    • Cancer patients’ use of primary care out-of-hours services: a cross-sectional study in Norway 

      Thoresen, Camilla Kjellstadli; Sandvik, Hogne; Hunskaar, Steinar (Peer reviewed; Journal article, 2016)
      Objective: To investigate how cancer patients in Norway use primary care out-of-hours (OOH) services and describe different contact types and procedures. Design: A retrospective cross-sectional registry study using a billing ...

    • Cancer Predisposition Sequencing Reporter (CPSR): A flexible variant report engine for high-throughput germline screening in cancer 

      Nakken, Sigve; Saveliev, Vladislav; Hofmann, Oliver; Møller, Pål; Myklebost, Ola; Hovig, Eivind (Journal article; Peer reviewed, 2021)
      The value of high-throughput germline genetic testing is increasingly recognized inclinical cancer care. Disease-associated germline variants in cancer patients areimportant for risk management and surveillance, surgical ...

    • The Cancer Registry of Norway – “a ground for scientific harvesting” 

      Engeland, Anders; Nystad, Wenche; Selmer, Randi Marie (Journal article; Peer reviewed, 2022)
      The Cancer Registry of Norway (CRN) has been important in registry-based research in Norway for decades. The use of CRN in combination with other population-based registries and health surveys have been the basis for ...

    • Cancer related mortality in multiple sclerosis. A population based cohort study 

      Grytten, Nina; Myhr, Kjell-Morten; Celius, Elisabeth Gulowsen; Benjaminsen, Espen; Midgard, Rune; Vatne, Anita; Aarseth, Jan Harald; Mannseth, Janne; Torkildsen, Øivind Fredvik Grytten (Journal article; Peer reviewed, 2023)
      Background: Cancer is a major cause of death, but how cancer influences mortality risk in Multiple Sclerosis (MS) is unclear. Objectives: Determine all-cause mortality and mortality following a cancer diagnosis among ...

    • Cancer risk in children of mothers with epilepsy and high-dose folic acid use during pregnancy 

      Vegrim, Håkon Magne; Dreier, Julie Werenberg; Alvestad, Silje; Gilhus, Nils Erik; Gissler, Mika; Igland, Jannicke; Leinonen, Maarit; Tomson, Torbjörn; Sun, Yuelian; Zoega, Helga; Christensen, Jakob; Bjørk, Marte-Helene (Journal article; Peer reviewed, 2022)
      Importance: Women with epilepsy are recommended high doses of folic acid before and during pregnancy owing to risk of congenital anomalies associated with antiseizure medications. Whether prenatal exposure to high-dose ...

    • Cancer risk in individuals with major birth defects: large Nordic population based case-control study among children, adolescents, and adults 

      Daltveit, Dagrun Slettebø; Klungsøyr, Kari; Engeland, Anders; Ekbom, Anders; Gissler, Mika; Glimelius, Ingrid; Grotmol, Tom; Madanat-Harjuoja, Laura M.; Ording, Anne Gulbech; Sæther, Solbjørg Makalani Myrtveit; Sørensen, Henrik Toft; Troisi, Rebecca; Bjørge, Tone (Journal article; Peer reviewed, 2020)
      Objective To examine associations between birth defects and cancer from birth into adulthood. Design Population based nested case-control study. Setting Nationwide health registries in Denmark, Finland, Norway, ...

    • Cancer risk in the siblings of individuals with major birth defects: a large Nordic population-based case-control study 

      Daltveit, Dagrun Slettebø; Klungsøyr, Kari; Engeland, Anders; Ekbom, Anders; Gissler, Mika; Glimelius, Ingrid; Grotmol, Tom; Madanat-Harjuoja, Laura; Ording, Anne Gulbech; Sørensen, Henrik Toft; Troisi, Rebecca; Bjørge, Tone (Journal article; Peer reviewed, 2023)
      Background: Individuals with major birth defects are at increased risk of developing cancer, indicating a common aetiology. However, whether the siblings of individuals with birth defects are also at an increased risk of ...

    • Cancer Stem Cell-Related Markers in Normal and Neoplastic Oral Mucosa. A study on human samples and experimental models 

      Osman, Tarig Al-Hadi (Doctoral thesis, 2014-06-04)
      The existence of cancer stem cells (CSCs) in solid cancers is still a controversial issue. Several markers were successfully used to enrich for cells with stem cell-like properties in oral squamous cell carcinoma (OSCC). ...

    • Cancer stem cells as mediators of treatment resistance in brain tumors: Status and controversies 

      Sakariassen, Per Øystein; Immervoll, Heike; Chekenya, Martha (Peer reviewed; Journal article, 2007-11)
      Malignant primary brain tumors are characterized by a short median survival and an almost 100% tumorrelated mortality. Despite the addition of new chemotherapy regimes, the overall survival has improved marginally, and ...

    • Cancer worry among Norwegian male BRCA1/2 mutation carriers 

      Strømsvik, Nina; Råheim, Målfrid; Gjengedal, Eva (Peer reviewed; Journal article, 2011-09)
      This qualitative study explored the experiences of Norwegian men after being identified as BRCA 1/2 mutation-positive. Only limited knowledge is available on this topic; therefore, the aim of this study was to gain a deeper ...

    • Cancer-associated fibroblasts in desmoplastic tumors: emerging role of integrins 

      Zeltz, Cedric; Primac, Irina; Murugan Erusappan, Pugazendhi; Alam, Jahedul; Noel, Agnes; Gullberg, Donald (Peer reviewed; Journal article, 2019)
      The tumor microenvironment (TME) is a complex meshwork of extracellular matrix (ECM) macromolecules filled with a collection of cells including cancer-associated fibroblasts (CAFs), blood vessel associated smooth muscle ...

    • Cancer-Associated Ischemic Stroke: The Bergen NORSTROKE Study 

      Selvik, Henriette Aurora (Doctoral thesis, 2018-05-25)
      Background: Stroke and cancer are both leading causes of death and disability in the Western world. Cancer can lead to a hypercoagulable state that can cause ischemic stroke. Mechanisms include disturbance of the coagulation ...