Blar i Faculty of Medicine på tittel

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    • Determinants of Health Facility Utilization at Birth in South Sudan 

      Tongun, Justin Bruno; Mukunya, David; Tylleskär, Thorkild; Sebit, Mohammed Boy; Tumwine, James K; Ndeezi, Grace (Peer reviewed; Journal article, 2019-07-09)
      South Sudan has a high maternal mortality ratio estimated at 800 deaths per 100,000 live births. Birth in health facilities with skilled attendants can lower this mortality. In this cross-sectional study, we determined the ...

    • Determinants of infant growth in Eastern Uganda: a community-based cross-sectional study 

      Engebretsen, Ingunn Marie S.; Tylleskär, Thorkild; Wamani, Henry; Karamagi, Charles A. S.; Tumwine, James K. (Peer reviewed; Journal article, 2008-12-22)
      Background: Child under-nutrition is a leading factor underlying child mortality and morbidity in Sub- Saharan Africa. Several studies from Uganda have reported impaired growth, but there have been few if any community-based ...

    • Determinants of interindividual variation in exercise-induced cardiac troponin I levels 

      Bjørkavoll-Bergseth, Magnus; Erevik, Christine Bjørkvik; Kleiven, Øyunn; Eijsvogels, Thijs M. H.; Skadberg, Øyvind; Frøysa, Vidar; Wiktorski, Tomasz; Auestad, Bjørn; Edvardsen, Thor; Aakre, Kristin Moberg; Ørn, Stein (Journal article; Peer reviewed, 2021)
      Background: Postexercise cardiac troponin levels show considerable interindividual variations. This study aimed to identify the major determinants of this postexercise variation in cardiac troponin I (cTnI) following 3 ...

    • Determinants of ligand binding and catalytic activity in the myelin enzyme 2′,3′-cyclic nucleotide 3′-phosphodiesterase 

      Raasakka, Arne; Myllykoski, Matti; Laulumaa, Saara; Lehtimäki, Mari; Härtlein, Michael; Moulin, Martine; Kursula, Inari; Kursula, Petri (Peer reviewed; Journal article, 2015-11-13)
      2′,3′-cyclic nucleotide 3′-phosphodiesterase (CNPase) is an enzyme highly abundant in the central nervous system myelin of terrestrial vertebrates. The catalytic domain of CNPase belongs to the 2H phosphoesterase superfamily ...

    • Determinants of male involvement in the prevention of mother-to-child transmission of HIV programme in Eastern Uganda: a cross-sectional survey 

      Byamugisha, Robert; Tumwine, James K.; Semiyaga, Nulu; Tylleskär, Thorkild (Peer reviewed; Journal article, 2010-06-23)
      Background: Mother-to-child transmission of HIV (MTCT) accounts for over 95% of all paediatric HIV infections worldwide. Several studies have shown that male participation in the antenatal care of their spouses together ...

    • Determinants of penetrance and variable expressivity in monogenic metabolic conditions across 77,184 exomes 

      Goodrich, Julia K.; Singer-Berk, Moriel; Son, Rachel; Sveden, Abigail; Wood, Jordan; England, Eleina; Cole, Joanne B.; Weisburd, Ben; Watts, Nick; Caulkins, Lizz; Dornbos, Peter; Koesterer, Ryan; Zappala, Zachary; Zhang, Haichen; Maloney, Kristin A.; Dahl, Andy; Aguilar-Salinas, Carlos A.; Atzmon, Gil; Barajas-Olmos, Francisco; Barzilai, Nir; Blangero, John; Boerwinkle, Eric; Bonnycastle, Lori L.; Bottinger, Erwin; Bowden, Donald W.; Centeno-Cruz, Federico; Chambers, John C.; Chami, Nathalie; Chan, Edmund; Chan, Juliana; Cheng, Ching-Yu; Cho, Yoon Shin; Contreras-Cubas, Cecilia; Córdova, Emilio; Correa, Adolfo; DeFronzo, Ralph A.; Duggirala, Ravindranath; Dupuis, Josée; Garay-Sevilla, Ma Eugenia; García-Ortiz, Humberto; Gieger, Christian; Glaser, Benjamin; González-Villalpando, Clicerio; Gonzalez, Ma Elena; Grarup, Niels; Groop, L; Gross, Myron; Haiman, Christopher A.; Han, Sohee; Hanis, Craig L.; Hansen, Torben; Heard-Costa, Nancy L.; Henderson, Brian E.; Hernandez, Juan Manuel Malacara; Hwang, Mi Yeong; Islas-Andrade, Sergio; Jørgensen, Marit E.; Kang, Hyun Min; Kim, Bong-Jo; Kim, Young Jin; Koistinen, Heikki A.; Kooner, Jaspal Singh; Kuusisto, Johanna; Kwak, Soo-Heon; Laakso, Markku; Lange, Leslie; Lee, Jong-Young; Lee, Juyoung; Lehman, Donna M.; Linneberg, Allan; Liu, Jianjun; Loos, Ruth J. F.; Lyssenko, Valeriya; Ma, Ronald C. W.; Martínez-Hernández, Angélica; Meigs, James B.; Meitinger, Thomas; Mendoza-Caamal, Elvia; Mohlke, Karen L.; Morris, AD; Morrison, Alanna C.; Ng, Maggie C. Y.; Nilsson, Peter M.; O’Donnell, Christopher J.; Orozco, Lorena; Palmer, Colin N. A.; Park, Kyong Soo; Post, W; Pedersen, Oluf; Preuss, Michael; Psaty, Bruce M.; Reiner, Alexander P.; Revilla-Monsalve, Cristina; Rich, Stephen S.; Rotter, Jerome I.; Saleheen, Danish; Schurmann, Claudia; Sim, Xueling; Sladek, Rob; Small, Kerrin S.; So, Wing Yee; Spector, Timothy D.; Strauch, Konstantin; Strom, Tim M.; Tai, E. Shyong; Tam, Claudia H. T.; Teo, Yik Ying; Thameem, Farook; Tomlinson, Brian; Tracy, Russell P.; Tuomi, Tiinamaija; Tuomilehto, Jaakko; Tusié-Luna, Teresa; van Dam, Rob M.; Vasan, Ramachandran S.; Wilson, James G.; Witte, Daniel R.; Wong, Tien-Yin; Burtt, Noël P.; Zaitlen, Noah; McCarthy, Mark I.; Boehnke, Michael; Pollin, Toni I.; Flannick, Jason; Mercader, Josep M.; O’Donnell-Luria, Anne; Baxter, Samantha; Florez, Jose C.; MacArthur, Daniel G.; Udler, MS (Journal article; Peer reviewed, 2021)
      Hundreds of thousands of genetic variants have been reported to cause severe monogenic diseases, but the probability that a variant carrier develops the disease (termed penetrance) is unknown for virtually all of them. ...

    • Determinants of periodontal health in pregnant women and association with infants’ anthropometric status: a prospective cohort study from Eastern Uganda 

      Wandera, Margaret Nekesa; Åstrøm, Anne Nordrehaug; Okullo, Isaac; Tumwine, James K. (Peer reviewed; Journal article, 2012-09-05)
      Background: Preterm-low birth weight delivery is a major cause of infant morbidity and mortality in sub Saharan Africa and has been linked to poor periodontal health during pregnancy. This study investigated predisposing ...

    • Determinants of self-perceived risk of HIV infection: population-based observations in Zambia 

      Mwangala, Sheila Monde (Master thesis, 2008-06-06)
      Background Perception of risk of HIV infection has been suggested to be an important area of study as it can be an assumed to be an indicator of one’s understanding of susceptibility to HIV infection and a precursor to ...

    • Determinants of trabecular bone score and prevalent vertebral fractures in women with fragility fractures: a cross-sectional sub-study of NoFRACT 

      Borgen, Tove Tveitan; Bjørnerem, Åshild; Solberg, Lene Bergendal; Andreasen, Camilla; Figved, Wender; Hübschle, Lars Michael; Stenbro, May-Britt; Basso, Trude; Dahl, cecilie; Stutzer, Jens-Meinhard; Frihagen, Frede; Eriksen, Erik Fink; Nordsletten, Lars; Hansen, Ann Kristin; Apalset, Ellen Margrete; Gjertsen, Jan Erik; Lund, Ida (Peer reviewed; Journal article, 2020)
      Summary: Determinants of trabecular bone score (TBS) and vertebral fractures assessed semiquantitatively (SQ1–SQ3) were studied in 496 women with fragility fractures. TBS was associated with age, parental hip fracture, ...

    • Determinants of Treatment Adherence Among Smear-Positive Pulmonary Tuberculosis Patients in Southern Ethiopia 

      Shargie, Estifanos Biru; Lindtjørn, Bernt (PLoS Medicine 2007 4(2): e37, Peer reviewed; Journal article, 2007-02-13)
      Background: Defaulting from treatment remains a challenge for most tuberculosis control programmes. It may increase the risk of drug resistance, relapse, death, and prolonged infectiousness. The aim of this study was to ...

    • Determinants of utilization of antenatal and delivery care at the community level in rural Bangladesh 

      Pervin, Jesmin; Venkateswaran, Mahima; Nu, U. Tin; Rahman, Monjur; O’Donnell, Brian F.; Friberg, Ingrid Kristina; Rahman, Anisur; Frøen, J. Frederik (Journal article; Peer reviewed, 2021-09-28)
      Background: Timely utilization of antenatal care and delivery services supports the health of mothers and babies. Few studies exist on the utilization and determinants of timely ANC and use of different types of health ...

    • Determinants of vitamin D status 

      Rise, Håvard Opheim (Master thesis, 2020-06-27)

    • Determinants of voluntary HIV counseling and testing (VCT) uptake among men who have sex with men (MSM) in Nepal 

      Shrestha, Rachana (Master thesis, 2015-05-29)
      Background: In an era of treatment as prevention, voluntary HIV counseling and testing (VCT) is a crucial point to link individuals with HIV infection with treatment, care and support. VCT also promotes safer behavior (e.g. ...

    • Determination of conformations adopted by CXCR4 and CCR5 at the cell surface 

      Dyrhaug, Sunniva Yngvil (Master thesis, 2010-05-20)
      The chemokines and their receptors constitute many important physiological functions in the human body. The chemokine receptors belong to the family of G-protein coupled receptors, characterized by 7 α-helices penetrating ...

    • Determination of lower cut-off levels of adalimumab associated with biochemical remission in Crohn's disease 

      Carlsen, Arne; Omdal, Roald; Karlsen, Lars Normann; Kvaløy, Jan Terje; Aabakken, Lars; Steinsbø, Øyvind; Bolstad, Nils; Warren, David; Lundin, Knut Erik Aslaksen; Grimstad, Tore (Peer reviewed; Journal article, 2020)
      Background and Aim: Adalimumab is administered and dosed using a standardized treatment regimen. Although therapeutic drug monitoring (TDM) may help optimize treatment efficacy, the lower cut‐off concentration of adalimumab ...

    • Determining universal processes related to best outcome in emergency abdominal surgery: A multicentre, international, prospective cohort study 

      Bhangu, Aneel; Fitzgerald, J. Edward; Fergusson, Stuart; Khatri, Chetan; Holmer, Hampus; Søreide, Kjetil; Harrison, Ewen M. (Peer reviewed; Journal article, 2014-10-29)
      Introduction: Emergency abdominal surgery outcomes represent an internationally important marker of healthcare quality and capacity. In this study, a novel approach to investigating global surgical outcomes is proposed, ...

    • Developing a core outcome set for hospital deprescribing trials for older people under the care of a geriatrician 

      Martin-Kerry, Jacqueline; Taylor, Jo; Scott, Sion; Patel, Martyn; Wright, David John; Clark, Allan; Turner, David; Alldred, David Phillip; Murphy, Katherine; Keevil, Victoria; Witham, Miles D.; Kellar, Ian; Bhattacharya, Debi (Journal article; Peer reviewed, 2022)
      Background Half of older people are prescribed unnecessary/inappropriate medications that are not routinely deprescribed in hospital hence there is a need for deprescribing trials. We aimed to develop a Core Outcome Set ...

    • Developing a flow cytometric method to characterize human T cell responses against the enteric protozoan parasite Giardia lamblia 

      Saghaug, Christina Skår (Master thesis, 2014-06-03)
      Giardia lamblia is an enteric protozoan parasite, which causes infection in humans worldwide. The impact of the infection varies from asymptomatic carriers to severe disease such as malabsorption syndrome. Evidence for ...

    • Developing a framework for sustainable actions that civil society can undertake to mitigate the impact that microplastics have on human health. A scoping review of literature. 

      Messing, David Aaron (Master thesis, 2021-05-21)

    • Developing a novel femoral stem in hip arthroplasty. An innovation process using a weight-bearing animal model 

      Harboe, Knut (Doctoral thesis, 2015-08-20)
      Introduction: To address the growing incidence of hip replacement revision, this project aimed to find a stem that would fulfil three criteria. First, solid osteointegration and long survival of the implant. Second, easy ...