Blar i Faculty of Medicine på tittel
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Investigating trends in HIV transmission and risk factors in Zambia
(Doctoral thesis, 2008-04-25)The objective of HIV surveillance is to document trends in HIV prevalence and transmission risk in order to make informed policies and to guide prevention and care/treatment programmes. Zambia established a comprehensive ... -
Investigation of complement component C4 copy number variation in human longevity
(Peer reviewed; Journal article, 2014-01-22)Genetic factors have been estimated to account for about 25% of the variation in an adult’s life span. The complement component C4 with the isotypes C4A and C4B is an effector protein of the immune system, and differences ... -
Investigation of Cross-Reactivity of Anti-Ephrin-B2 Antibody to Other Ephrin-B Members in an Immunohistochemical Study in a Cohort of Oral Squamous Cell Carcinoma
(Journal article, 2022)Ephrin-B1,-B2 and -B3 proteins share a high degree of sequence similarity. Investigation of these proteins as putative prognostic markers in human cancers including oral squamous cell carcinoma (OSCC) has been limited by ... -
Investigation of immune cells in psoriasis patients treated with infliximab
(Master thesis, 2021-05-20)Psoriasis is a chronic inflammatory disease that manifests in the skin affecting both sexes equally and all ages. In Norway, the prevalence reaches 11.43% in adults. Both genetics and environment factors are important in ... -
Investigation of mechanisms leading to early aseptic loosening of hip prostheses. A retrieval study of 27 failed cases of cemented Spectron EF stem in combination with Reflection acetabular cup
(Master thesis, 2016-05-18)Background: More than 1 million people with arthroplasties undergo total hip arthroplasty (THA) surgery every year worldwide. In Norway more than 10 % of the THA cases needed revision operations due to aseptic loosening. ... -
Investigation of perioperative work processes in provision of antibiotic prophylaxis: a prospective descriptive qualitative study across surgical specialties in Norway
(Peer reviewed; Journal article, 2019)Abstract Objective: Surgical site infections are known postoperative complications, yet the most preventable of healthcare-associated infections. Correct provision of surgical antibiotic prophylaxis (SAP) is crucial. Use ... -
Investigation of predictive markers in patients with metastatic melanoma treated with bevacizumab
(Doctoral thesis, 2016-11-22)Background: The incidence of malignant melanoma is still rising among fair- skinned people worldwide, and it is among the three major cancer types in young adults in Norway. Progression free survival and overall survival ... -
Investigation of protein signalling pathways activated by sonoporation in cancer
(Master thesis, 2018-06-29)Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal cancers worldwide. patients with a metastatic PDAC only survive 3 – 5 months if left untreated and less than 25% of diagnosed patients are eligible for ... -
Investigation of the apoptotic pathway in glioblastoma in the context of suicide gene therapy
(Master thesis, 2023-06-01)Glioblastoma is a highly malignant, aggressive and most common primary brain tumor in adults. Tremendous research efforts have been conducted in the field of GBM treatment discovery and succcess has only been achieved at ... -
Investigation of the Role of BCR/ABL1 in Neutrophil Extracellular Trap (NET) Formation in Chronic Myeloid Leukemia (CML)
(Master thesis, 2022-06-01)Neutrophil extracellular traps (NETs) represent a rather newly discovered antimicrobial mechanism first described by Brinkmann and co-workers in 2004. NETs are extracellular structures composed of decondensed chromatin ... -
Investigations of the cancer therapeutic and protective effects of warfarin-mediated inhibition of the receptor tyrosine kinase AXL
(Doctoral thesis, 2017-11-17)Cancer is a major health issue all over the world. Cancer related deaths are one of the major causes of deaths, and are in > 90 % of the cases related to metastatic development, and spread of the cancer outside the primary ... -
Involvement in emergency situations by primary care doctors on-call in Norway - a prospective population-based observational study
(Peer reviewed; Journal article, 2010-03-06)Background: Primary care doctors on-call in the emergency primary health care services in Norway are, together with the ambulances, the primary resources for handling emergencies outside hospitals. There is a lack of ... -
Involvement of the 14-3-3 Gene Family in Autism Spectrum Disorder and Schizophrenia: Genetics, Transcriptomics and Functional Analyses
(Journal article; Peer reviewed, 2020)The 14-3-3 protein family are molecular chaperones involved in several biological functions and neurological diseases. We previously pinpointed YWHAZ (encoding 14-3-3ζ) as a candidate gene for autism spectrum disorder (ASD) ... -
Involvement of the Private Retail Pharmacies in Pakistan Tuberculosis Control
(Master thesis, 2015-11-29)Tuberculosis is the second leading cause of death globally from a contagious disease. Pakistan is at 4th position among the twenty two high TB burden countries. National tuberculosis control programme (NTP) Pakistan has ... -
Involving people with diabetes and the wider community in diabetes research: a realist review protocol
(Peer reviewed; Journal article, 2015-11-04)Background: Patient and public involvement in diabetes research is now actively encouraged in different countries because it is believed that involving people with experience of the condition will improve the quality and ... -
Iodine concentration in breastmilk and urine among lactating women of Bhaktapur, Nepal
(Peer reviewed; Journal article, 2016-04-28)Adequate iodine concentration in breastmilk (BMIC) is essential for optimal neonatal thyroid hormone synthesis and neurological development in breastfed infants. For many decades, iodine deficiency has been a public health ... -
Iodine content of dietary supplements available on the Norwegian market
(Master thesis, 2021-05-18)Background: Insufficient iodine intake has been reported in groups of the Norwegian population. This is of concern, as iodine is an essential nutrient required throughout life. With few dietary sources of iodine, supplementation ... -
Iodine deficiency in a study population of Norwegian pregnant women - results from the Little in Norway study (LiN)
(Peer reviewed; Journal article, 2018-04-20)Iodine sufficiency is particularly important in pregnancy, where median urinary iodine concentration (UIC) in the range of 150–250 µg/L indicates adequate iodine status. The aims of this study were to determine UIC and ... -
Iodine Nutrition and Iodine Supplement Initiation in Association with Thyroid Function in Mildly-to-Moderately Iodine-Deficient Pregnant and Postpartum Women
(Journal article; Peer reviewed, 2021)Background: Whereas the adverse effects of severe iodine deficiency during pregnancy are well documented, the effects of mild-to-moderate deficiency are not well established. Objectives: We aimed to explore whether ...