Blar i Faculty of Medicine på tittel
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Overweight and eating disorders in people with epilepsy
(Doctoral thesis, 2019-09-27)Background: Epilepsy is a common neurological disease and occurs in 0.7-1.3 % of the general population. It is associated with comorbid mental disorders such as depression and anxiety, and with a high risk for adverse ... -
Overweight and obesity in children: a study of weight-related anthropometric variables in childhood
(Doctoral thesis, 2015-11-13) -
Overweight and obesity in Norwegian children. Trends, current prevalence, effect of socio-demographic factors and parental perception
(Doctoral thesis, 2010-10-22)Background: The prevalence of paediatric overweight and obesity has shown a rapid increase in most parts of the world during the last decades. Estimates of prevalence of overweight and obesity in Norwegian children have ... -
Ownership and use of long-lasting insecticidal nets for malaria prevention in Butajira area, south-central Ethiopia: complex samples data analysis
(Peer reviewed; Journal article, 2014-01-31)Background: Despite the encroaching of endemic malaria to highland-fringe areas above 2000 meters above sea level in Ethiopia, there is limited information on ownership and use of mosquito nets for malaria prevention. Thus, ... -
Oxidative Stress in Animal Models of Acute and Chronic Renal Failure
(Peer reviewed; Journal article, 2019-02-11)Introduction. Kidney disease is a worldwide health and economic burden, with rising prevalence. The search for biomarkers for earlier and more effective disease screening and monitoring is needed. Oxidative stress has been ... -
Oxidative stress in susceptibility to breast cancer: study in Spanish population
(Peer reviewed; Journal article, 2014-11-21)Background: Alterations in the redox balance are involved in the origin, promotion and progression of cancer. Inter-individual differences in the oxidative stress regulation can explain a part of the variability in cancer ... -
Oxidative Stress in the Pathophysiology of Kidney Disease: Implications for Noninvasive Monitoring and Identification of Biomarkers
(Journal article; Peer reviewed, 2020)Kidney disease represents a serious global health problem. One of the main concerns is its late diagnosis, only feasible in a progressed disease state. The lack of a clinical manifestation in the early stages and the fact ... -
OXR1A, a Coactivator of PRMT5 Regulating Histone Arginine Methylation
(Journal article; Peer reviewed, 2020)Oxidation resistance gene 1 (OXR1) protects cells against oxidative stress. We find that male mice with brain-specific isoform A knockout (Oxr1A−/−) develop fatty liver. RNA sequencing of male Oxr1A−/− liver indicates ... -
Oxygen concentration in inhaled gas and nitric oxide concentration in exhaled gas. Is nitric oxide concentration in exhaled gas a useful marker for exposure to hyperoxia?
(Doctoral thesis, 2014-04-10)Background: Exposure to partial pressures of oxygen (PO2) higher than 50 kPa may result in toxic effects on the lungs with reduced vital capacity, maximal expiratory flow rates and diffusion capacity. The risk of developing ... -
Oxygen saturation after birth in resuscitated neonates in Uganda: A video-based observational study
(Journal article; Peer reviewed, 2022)Background Monitoring of peripheral capillary oxygen saturation (SpO2) during neonatal resuscitation is standard of care in high-resource settings, but seldom performed in low-resource settings. We aimed to measure SpO2 ... -
Oxygen-dependent regulation of tumor growth and metastasis in human breast cancer xenografts
(Peer reviewed; Journal article, 2017-08-23)Background: Tumor hypoxia is relevant for tumor growth, metabolism, resistance to chemotherapy and metastasis. We have previously shown that hyperoxia, using hyperbaric oxygen treatment (HBOT), attenuates tumor growth and ... -
p53 protein biosignatures in acute myeloid leukemia
(Doctoral thesis, 2006-03-10)p53 is a tumor suppressor protein often regarded as the guardian of the genome. It is a highly connected protein involved in many signaling processes in the cell. The inactivation of p53 through genetic mutations in TP53 ... -
p53 Protein Isoform Profiles in AML: Correlation with Distinct Differentiation Stages and Response to Epigenetic Differentiation Therapy
(Journal article; Peer reviewed, 2021)p53 protein isoform expression has been found to correlate with prognosis and chemotherapy response in acute myeloid leukemia (AML). We aimed to investigate how p53 protein isoforms are modulated during epigenetic ... -
Paediatric Contacts of Adult COVID-19 Patients: Clinical Parameters, Risk Factors, and Outcome
(Journal article; Peer reviewed, 2021)Background. There is insufficient data in Pakistan and in South Asia regarding paediatric COVID-19 demographics and related parameters. The main aim of this study was to assess the paediatric population exposed to SARS-CoV-2 ... -
Paediatric HIV-1 infection in Uganda. Natural history and early antiretroviral treatment response
(Doctoral thesis, 2011-10-07)Paediatric HIV-1 infection remains a major problem for sub-Saharan Africa with over 1300 new infections daily. Infected children have a high mortality with 50% dying by 2 years of age. Access to antiretroviral therapy (ART) ... -
Paediatric kidney stone surgery: state-of-the-art review
(Journal article; Peer reviewed, 2023)While urolithiasis in children is rare, the global incidence is rising, and the volume of minimally invasive surgeries being performed reflects this. There have been many developments in the technology, which have supported ... -
Paediatric surgical conditions in malawi-a cross-sectional nationwide household survey
(Journal article; Peer reviewed, 2021)Background Untreated surgical conditions may lead to lifelong disability in children. Treating children with surgical conditions may reduce long-term effects of morbidity and disability. Unfortunately, low- and middle-income ... -
Paediatric Ureteroscopy (P-URS) reporting checklist: a new tool to aid studies report the essential items on paediatric ureteroscopy for stone disease
(Journal article, 2023)The burden of urolithiasis in children is increasing and this is mirrored by the number of surgical interventions in the form of ureteroscopy (URS). There exist many challenges in performing this surgery for this special ... -
The Pah-R261Q mouse reveals oxidative stress associated with amyloid-like hepatic aggregation of mutant phenylalanine hydroxylase
(Journal article; Peer reviewed, 2021)Phenylketonuria (PKU) is caused by autosomal recessive variants in phenylalanine hydroxylase (PAH), leading to systemic accumulation of L-phenylalanine (L-Phe) that may reach neurotoxic levels. A homozygous Pah-R261Q mouse, ... -
Pain and pain tolerance in whiplash-associated disorders:A population-based study
(Peer reviewed; Journal article, 2015)Background: Pain is a cardinal symptom in individuals with whiplash-associated disorders (WAD). We aimed to compare pain characteristics between individuals with WAD and individuals reporting chronic pain from other causes, ...