Blar i Faculty of Medicine på tittel
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Risk of stroke in genetically verified familial hypercholesterolemia: A prospective matched cohort study
(Journal article; Peer reviewed, 2022)Background and aims Individuals with familial hypercholesterolemia (FH), causing severely elevated LDL-C, are expected to have a higher risk of ischemic stroke. The risk of hemorrhagic stroke and impact of statin use are, ... -
Risk of stroke the year following a delivery after using assisted reproductive technologies
(Journal article; Peer reviewed, 2023)Background Studies indicate that individuals who deliver after assisted reproductive technologies (ART) may have an increased risk of cardiovascular disease (CVD). A recent large study from the U.S. showed a higher risk ... -
Risk of Subsequent Preeclampsia by Maternal Country of Birth: A Norwegian Population-Based Study
(Journal article; Peer reviewed, 2023)In this nationwide population-based study, we investigated the associations of preeclampsia in the first pregnancy with the risk of preeclampsia in the second pregnancy, by maternal country of birth using data from the ... -
Risk of total hip arthroplasty after elite sport: linking 3304 former world-class athletes with the Norwegian Arthroplasty Register
(Journal article; Peer reviewed, 2023)Objectives: At present, there is no cure for osteoarthritis (OA), but severe hip joint degeneration can require total hip arthroplasty (THA). The literature on OA after elite sport is limited. We hypothesise that elite ... -
The risk of various types of cardiovascular diseases in mutation positive familial hypercholesterolemia; a review
(Journal article; Peer reviewed, 2022)Familial hypercholesterolemia (FH) is a common, inherited disease characterized by high levels of low-density lipoprotein Cholesterol (LDL-C) from birth. Any diseases associated with increased LDL-C levels including ... -
Risky Drinking among Norwegian Students: Associations with Participation in the Introductory Week, Academic Performance and Alcohol-related Attitudes
(Peer reviewed; Journal article, 2016-09)AIMS – Substantial increase in heavy drinking upon transition from high school to college is common. Norwegian universities and university colleges arrange yearly introductory weeks to welcome new students. It has been ... -
RNA sequencing and proteomic profiling reveal different alterations by dietary methylmercury in the hippocampal transcriptome and proteome in BALB/c mice
(Journal article; Peer reviewed, 2021)Methylmercury (MeHg) is a highly neurotoxic form of mercury (Hg) present in seafood. Here, we recorded and compared proteomic and transcriptomic changes in hippocampus of male BALB/c mice exposed to two doses of MeHg. Mice ... -
RNA splicing factor USP39 promotes glioma progression by inducing TAZ mRNA maturation
(Peer reviewed; Journal article, 2019)Increasing evidence demonstrates that ubiquitin specific protease 39 (USP39) plays an oncogenic role in various human tumors. Here, using expression analysis of the publicly available Oncomine database, clinical glioma ... -
RNA viruses in community-acquired childhood pneumonia in semi-urban Nepal; a cross-sectional study
(Peer reviewed; Journal article, 2009-07-27)Background: Pneumonia is among the main causes of illness and death in children <5 years of age. There is a need to better describe the epidemiology of viral community-acquired pneumonia (CAP) in developing countries. ... -
The RNA-Binding Protein hnRNP K Mediates the Effect of BDNF on Dendritic mRNA Metabolism and Regulates Synaptic NMDA Receptors in Hippocampal Neurons
(Peer reviewed; Journal article, 2017-11)Brain-derived neurotrophic factor (BDNF) is an important mediator of long-term synaptic potentiation (LTP) in the hippocampus. The local effects of BDNF depend on the activation of translation activity, which requires the ... -
The road to equitable healthcare: A conceptual model developed from a qualitative study of Syrian refugees in Norway
(Journal article; Peer reviewed, 2022)Background Refugees in high-income countries face barriers to healthcare access even when they have the same rights and entitlements as the host population. Disadvantages in healthcare access contribute to differences in ... -
Role of a digital clinical decision-support system in management of chronic obstructive pulmonary disease
(Master thesis, 2021-05-18) -
Role of a Digital Clinical Decision–Support System in General Practitioners’ Management of COPD in Norway
(Journal article; Peer reviewed, 2021)Background: The study investigated if a web-based clinical decision–support system (CDSS) tool would improve general practitioners’ (GPs) accuracy of diagnosis and classification of patients with chronic obstructive pulmonary ... -
The Role of a Mission Organization in Building a Sustainable Government Hospital in Southern Ethiopia
(Journal article, 2020)In 1950, the Norwegian Lutheran Mission (NLM) began holistic mission work, including health work in Yirga Alem in Sidama in Southern Ethiopia. The hospital, which had served as a military hospital during the Italian war ... -
Role of Adipocyte SLC7A10 and Amino Acid Metabolism in Obesity and Insulin Resistance
(Doctoral thesis, 2020-12-18)Obesity is a rising global concern, associated with increased risk of developing metabolic syndrome, insulin resistance and type 2 diabetes. Chronic availability of excess nutrients may promote adipocyte dysfunction, ... -
The Role of Age in Cellular Responses to Microenvironmental Cues as a Breast Cancer Susceptibility Factor
(Doctoral thesis, 2016-05-09)Aging is the critical risk factor for many forms of cancer. We used the mammary gland as a model system to study the impact of age on human epithelia in which age is the greatest risk factor for cancer. Dysfunctional ... -
The role of anti-citrullinated protein antibody reactivities in an inception cohort of patients with rheumatoid arthritis receiving treat-to-target therapy
(Peer reviewed; Journal article, 2018-07-13)Background: Anti-citrullinated protein antibody (ACPA) reactivities precede clinical onset of rheumatoid arthritis (RA), and it has been suggested that ACPA reactivities towards distinct target proteins may be associated ... -
The role of arginine and arginine-metabolizing enzymes during Giardia - host cell interactions in vitro
(Peer reviewed; Journal article, 2013-11-14)Background: Arginine is a conditionally essential amino acid important in growing individuals and under nonhomeostatic conditions/disease. Many pathogens interfere with arginine-utilization in host cells, especially nitric ... -
The role of autoantibodies in cell mediated autoimmune Addison`s disease
(Master thesis, 2012-05-31)Background: Addison`s disease (primary adrenal insufficiency) is a prototypic organ-specific autoimmune disease affecting the adrenal cortex. Autoimmune Addison`s disease (AAD) is often characterized by autoantibodies ... -
The Role of Axl in Cancer and Stem Cell Plasticity: in vivo Lineage Tracing and Imaging Mass Cytometry Analysis
(Master thesis, 2019-11-14)