Browsing Department of Biomedicine by Issue Date
Now showing items 1-20 of 739
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Expression of biomarkers (p53, transforming growth factor alpha, epidermal growth factor receptor, c-erbB-2/neu and the proliferative cell nuclear antigen) in oropharyngeal squamous cell carcinomas
(Peer reviewed; Journal article, 1999)Using immunohistochemistry, expression of p53, transforming growth factor-alpha (TGF-α), epidermal growth factor receptor (EGFR), c-erbB-2/neu and proliferating cell nuclear antigen (PCNA) was examined in 26 fresh frozen ... -
Stedcellenes fyringsmønster under påvirkning av belønning og forsøksapparatets geometri
(Master thesis, 2004)I hippocampus hos rotter finner man en type nerveceller som aktiveres stedspesifikt. Dette innebærer at de kun er aktive når rotten er i et bestemt område av omgivelsene. Disse cellene kalles stedceller (en: "place cells") ... -
Reduced Joint Pain after Short-term Duodenal Administration of Seal Oil in Patients with Inflammatory Bowel Disease: Comparison with Soy Oil
(Peer reviewed; Journal article, 2004)Background: Rheumatic joint pain is a common extraintestinal complication of inflammatory bowel disease (IBD). Because the high ratio of n-6 to n-3 fatty acids (FAs) of the Western diet might promote rheumatic disorders, ... -
In vivo mapping of tumor microcirculation parameters using dynamic contrast enhanced MR imaging
(Master thesis, 2004) -
The impact of different dietary sources of marine polyunsaturated fatty acids on the fatty acid composition of rat brain, liver and red blood cells.
(Master thesis, 2005-06)There is a general consensus that the physiological activity of fish oil can be ascribable to eicosapentaenoic acid (EPA, 20:5n-3) and docosahexaenoic acid (DHA, 22:6n-3). However, the form in which they are introduced in ... -
Lowering of tumor interstitial fluid pressure reduces tumor cell proliferation in a xenograft tumor model
(Peer reviewed; Journal article, 2006-02)High tumor interstitial fluid pressure (TIFP) is a characteristic of most solid tumors. TIFP may hamper adequate uptake of macromolecular therapeutics in tumor tissue. In addition, TIFP generates mechanical forces affecting ... -
Short-term duodenal seal oil administration normalised n-6 to n-3 fatty acid ratio in rectal mucosa and ameliorated bodily pain in patients with inflammatory bowel disease
(Peer reviewed; Journal article, 2006-03-20)Background: A high dietary intake of n-6 compared to n-3 fatty acids (FAs) may promote the production of pro-inflammatory eicosanoids and cytokines. In two recent studies, short-term (10- day) duodenal administration of ... -
Expression and effects of IL-1 and TNF-α in different experimental models of dental inflammation
(Doctoral thesis, 2006-07-04) -
Chronic mild stress - an anmial model of depression : from behavior to molecules
(Doctoral thesis, 2006-11-03) -
Studies on viral gene transfer and angiogenesis inhibition in experimental glioma models
(Doctoral thesis, 2006-11-03) -
Cognitive and psychosocial problems in children with epilepsy : a population-based approach
(Doctoral thesis, 2007-01-12) -
Hyperoxia retards growth and induces apoptosis and loss of glands and blood vessels in DMBA-induced rat mammary tumors
(Journal article, 2007-01-30)This study investigated the effects of hyperoxic treatment on growth, angiogenesis, apoptosis, general morphology and gene expression in DMBA-induced rat mammary tumors. Methods: One group of animals was exposed to normobaric ... -
LTP mechanisms in the dentate gyrus in vivo: BDNF signaling, translation control, and gene function
(Doctoral thesis, 2007-03-30) -
No Protection against DSS-induced Colitis by Short-term Pretreatment with Seal or Fish Oils in Rats
(Peer reviewed; Journal article, 2007-04-30)Background: Omega-3 (n-3) polyunsaturated fatty acids (PUFAs) have modulating effects in several chronic infl ammatory conditions. The aim of the present study was to test whether prior short-term dietary supplementation ... -
Improved Quantification of Prostaglandins in Biological Samples by Optimizing Simultaneously the Relationship Eicosanoid/Internal-Standard and Using Liquid Chromatography Tandem Mass Spectrometry
(Peer reviewed; Journal article, 2007-07)Although a wide variety of articles on quantification of eicosanoids by using internal standards are published every year, little has been done on how much internal standard should be added. This article demonstrates that ... -
Specificity of commonly used cyclic nucleotides with PKA, PKG and Epac-implementing microcalorimetry to determine PDE activities
(Conference lecture, 2007-07-25) -
Replication protein A prevents accumulation of single-stranded telomeric DNA in cells that use alternative lengthening of telomeres
(Peer reviewed; Journal article, 2007-10-24)The activation of a telomere maintenance mechanism is required for cancer development in humans. While most tumors achieve this by expressing the enzyme telomerase, a fraction (5–15%) employs a recombination-based mechanism ... -
Cancer stem cells as mediators of treatment resistance in brain tumors: Status and controversies
(Peer reviewed; Journal article, 2007-11)Malignant primary brain tumors are characterized by a short median survival and an almost 100% tumorrelated mortality. Despite the addition of new chemotherapy regimes, the overall survival has improved marginally, and ...