Browsing Department of Biomedicine by Author "Wang, Xiang"
Now showing items 1-5 of 5
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Developing Neurons Form Transient Nanotubes Facilitating Electrical Coupling and Calcium Signaling with Distant Astrocytes
Wang, Xiang; Bukoreshtliev, Nickolay Vassilev; Gerdes, Hans-Hermann (Peer reviewed; Journal article, 2012-10-11)Despite the well-documented cooperation between neurons and astrocytes little is known as to how these interactions are initiated. We show here by differential interference contrast microscopy that immature hippocampal ... -
Multi-Level Communication of Human Retinal Pigment Epithelial Cells via Tunneling Nanotubes
Wittig, Dierk; Wang, Xiang; Walter, Cindy; Gerdes, Hans-Hermann; Funk, Richard H. W.; Roehlecke, Cora (Peer reviewed; Journal article, 2012-03-22)Background: Tunneling nanotubes (TNTs) may offer a very specific and effective way of intercellular communication. Here we investigated TNTs in the human retinal pigment epithelial (RPE) cell line ARPE-19. Morphology of ... -
TNT-Induced Phagocytosis: Tunneling Nanotubes Mediate the Transfer of Pro-Phagocytic Signals From Apoptotic to Viable Cells
Bittins, Margarethe; Wang, Xiang (Peer reviewed; Journal article, 2017-09)The exposure of phosphatidylserine (PS) on the surface membrane of apoptotic cells triggers the recruitment of phagocytic receptors and subsequently results in uptake by phagocytes. Here we describe how apoptotic cells can ... -
Transfer of mitochondria via tunneling nanotubes rescues apoptotic PC12 cells
Wang, Xiang; Gerdes, Hans-Hermann (Peer reviewed; Journal article, 2015-01-09)Tunneling nanotubes (TNTs) are F-actin-based membrane tubes that form between cells in culture and in tissues. They mediate intercellular communication ranging from electrical signalling to the transfer of organelles. Here, ... -
Tunneling nanotubes: Diversity in morphology and structure
Austefjord, Magnus Wiger; Gerdes, Hans-Hermann; Wang, Xiang (Peer reviewed; Journal article, 2014-02-06)Tunneling nanotubes (TNTs) are recently discovered thin membranous tubes that interconnect cells. During the last decade, research has shown TNTs to be diverse in morphology and composition, varying between and within cell ...