Blar i Department of Clinical Medicine på tittel
Viser treff 1240-1259 av 2063
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Management of Bladder Pain Syndrome (BPS): A Practical Guide
(Journal article; Peer reviewed, 2022)Bladder pain syndrome (BPS) is a prevalent and pervasive disease. The physical and psychological sequelae can be very burdensome for the patient, and the condition represents a real challenge for the clinician as well. ... -
Management of cluster headache and other trigeminal autonomic cephalalgias in pregnancy and breastfeeding
(Journal article; Peer reviewed, 2021)Many clinicians lack experience in managing trigeminal autonomic cephalalgias (TACs) in pregnancy and lactation. In addition to cluster headache, TACs include hemicrania continua, paroxysmal hemicrania, and short-lasting ... -
Management of extrahepatic bile duct cysts
(Journal article; Peer reviewed, 2023) -
Management of kidney stone disease in pregnancy: A practical and evidence-based approach
(Journal article; Peer reviewed, 2022)Purpose of Review Suspected kidney stone disease during pregnancy is a difficult condition for health professionals to manage. This is partly due to the more limited range of diagnostic and therapeutic strategies, which ... -
MAP kinase phosphatase MKP-1 regulates p-ERK1/2 signaling pathway with fluoride treatment
(Journal article; Peer reviewed, 2021)Dental fluorosis is characterized by hypomineralization of tooth enamel caused by ingestion of excessive fluoride during enamel formation. Excess fluoride could have effects on the ERK signaling, which is essential for the ... -
Mapping Proteome Changes in Microsatellite Stable, Recurrent Colon Cancer Reveals a Significant Immune System Signature
(Journal article; Peer reviewed, 2022)Background/Aim: Better stratification of the risk of relapse will help select the right patients for adjuvant treatment and improve targeted therapies for patients with colon cancer. Materials and Methods: To understand ... -
A mass cytometry receptor occupancy study of natalizumab therapy in multiple sclerosis
(Doctoral thesis, 2020-06-05)Background: Natalizumab is a therapeutic antibody that effectively reduces disease activity in relapsing remitting multiple sclerosis (RRMS) by binding α4 integrin on leukocytes and preventing leukocyte migration into the ... -
Mass spectral profiling and multivariate analysis for detection of biomarker signatures. Application to multiple sclerosis
(Doctoral thesis, 2010-10-28)Mass spectrometry based protein profiling and biomarker discovery has given rise to the field of clinical proteomics. The underlying assumption is that proteins can provide information of diagnostic or therapeutic value ... -
Maternal and Newborn Vitamin D-Binding Protein, Vitamin D Levels, Vitamin D Receptor Genotype, and Childhood Type 1 Diabetes
(Peer reviewed; Journal article, 2019-04)OBJECTIVE Circumstantial evidence links 25-hydroxy vitamin D [25(OH)D], vitamin D–binding protein (DBP), vitamin D–associated genes, and type 1 diabetes (T1D), but no studies have jointly analyzed these. We aimed to ... -
The Maternal and Paternal Effects on Clinically and Surgically Defined Osteoarthritis
(Peer reviewed; Journal article, 2019-11)Objective: It is currently unknown whether osteoarthritis (OA) is inherited mainly from the mother, father, or both. This study was undertaken to explore the effect of maternal and paternal factors on hip, knee, and hand ... -
Maternal complications in pregnancy and childbirth for women with epilepsy: time trends in a nationwide cohort
(Peer reviewed; Journal article, 2019)Objective: Obstetric trends show changes in complication rates and maternal characteristics such as caesarean section, induced labour, and maternal age. To what degree such general time trends and changing patterns of ... -
Maternal pregnancy folate status and association to language impairment in children of women with epilepsy after prenatal antiseizure medication exposure
(Doctoral thesis, 2022-05-05)Background: 2-8 out of 1000 pregnancies occur in women with epilepsy. Most women use antiseizure medication (ASM) during pregnancy to avoid potentially harmful epileptic seizures. Fetal exposure to ASM is associated with ... -
Maternal Seafood Consumption and Serum Levels of p.p'-DDE and PCB-153 in Mother and Child
(Master thesis, 2014-05-15)Background: While seafood is a natural part of a healthy and balanced diet, it may also contain some undesirable environmental contaminants such as persistent organic pollutants (POPs), which can have detrimental effects ... -
Maturation of monocyte derived dendritic cells with OK432 boosts IL-12p70 secretion and conveys strong T-cell responses
(Peer reviewed; Journal article, 2011-01-05)Background: Design of tumour specific immunotherapies using the patients’ own dendritic cells (DC) is a fast advancing scientific field. The functional qualities of the DC generated in vitro are critical, and today’s gold ... -
Måleegenskaper ved den norske versjonen av Children’s Global Assessment Scale (CGAS)
(Peer reviewed; Journal article, 2018-10-23)Beskrivelse. Children’s Global Assessment Scale (CGAS) ble laget av David Shaffer og medarbeidere i 1983. Den skåres av kliniker og er et mål på barns psykososiale funksjonsnivå i den siste måneden før vurderingstidspunktet ... -
The MDM4 SNP34091 (rs4245739) C-allele is associated with increased risk of ovarian—but not endometrial cancer
(Peer reviewed; Journal article, 2016-02-11)The MDM4 protein (also known as MDMX or HDMX) is a negative regulator of p53, not only by direct interaction but also through its interaction with MDM2. Further, MDM4 overexpression and amplification have been observed in ... -
Measurement of renal functional response using iohexol clearance—a study of different outpatient procedures
(Peer reviewed; Journal article, 2019)Background: Glomerular filtration rate (GFR) increases after a heavy protein load; an increase termed renal functional response (RFR). Decreased RFR could be a marker of early kidney damage, but published methods are ... -
Measuring pressure pain threshold in the cervical region of dizzy patients-The reliability of a pressure algometer
(Peer reviewed; Journal article, 2018)Objectives: A tool for measuring neck pain in patients with dizziness is needed to further investigate the relationship between the two symptoms. The objective of this study was to examine the reliability and validity of ... -
The mediating effect of body mass index on the relationship between smoking and hip or knee replacement due to primary osteoarthritis. A population-based cohort study (the HUNT study)
(Peer reviewed; Journal article, 2017-12-28)To investigate the total effect of smoking on total hip or knee replacement (THR/TKR) due to primary osteoarthritis (OA) and to quantify the indirect effect of smoking through body mass index (BMI). Participants from the ... -
Medical abortion with mifepristone and home administration of misoprostol up to 63 days' gestation
(Peer reviewed; Journal article, 2014-05-23)Objective. To evaluate the acceptability and efficacy of medical abortion at home up to 63 days’ gestation without limits on travel distance to a registered institution. Design. Observational prospective study. Setting. ...