Browsing Department of Clinical Medicine by Title
Now showing items 1261-1280 of 2046
-
Meta-analysis and Meta-regression of Survival After Liver Transplantation for Unresectable Perihilar Cholangiocarcinoma
(Journal article; Peer reviewed, 2021)Objective: To systematically review studies reporting survival data following neoadjuvant chemoradiation and orthotopic liver transplantation (NCR-OLT) for unresectable perihilar cholangiocarcinoma (pCC). Background: ... -
Meta-analysis of Alzheimer’s disease on 9,751 samples from Norway and IGAP study identifies four risk loci
(Peer reviewed; Journal article, 2018-12-27)A large fraction of genetic risk factors for Alzheimer’s Disease (AD) is still not identified, limiting the understanding of AD pathology and study of therapeutic targets. We conducted a genome-wide association study (GWAS) ... -
Meta-analysis of whole-exome sequencing data from two independent cohorts finds no evidence for rare variant enrichment in Parkinson disease associated loci
(Journal article; Peer reviewed, 2020-10-01)Parkinson disease (PD) is a complex neurodegenerative disorder influenced by both environmental and genetic factors. While genome wide association studies have identified several susceptibility loci, many causal variants ... -
Metabolic alkalosis is the most common acid-base disorder in ICU patients
(Journal article, 2014-03-28) -
Metabolic consequences of perioperative oral carbohydrates in breast cancer patients - an explorative study
(Peer reviewed; Journal article, 2019-12-04)Background: The metabolic consequences of preoperative carbohydrate load in breast cancer patients are not known. The present explorative study investigated the systemic and tumor metabolic changes after preoperative ... -
Metabolic effects of diet containing blue mussel (Mytilus edulis) and blue mussel-fed salmon in a mouse model of obesity
(Journal article; Peer reviewed, 2023)Alternative feed ingredients for farmed salmon are warranted due to increasing pressure on wild fish stocks. As locally farmed blue mussels may represent an environmentally sustainable substitute with a lower carbon ... -
The metabolic syndrome and cardiometabolic risk factors in children and adolescents: Associations between different anthropometric measurements and cardiometabolic risk factors
(Master thesis, 2015-05-15)Introduction: The prevalence of pediatric obesity has increased worldwide during the last decades, and is currently a serious health challenge, as it causes extensive health problems in terms of cardiovascular comorbidities ... -
Metabolic syndrome as a risk factor for total hip or knee replacement due to primary osteoarthritis: A prospective cohort study (the HUNT study and the Norwegian arthroplasty register)
(Peer reviewed; Journal article, 2018-01-10)Objective: Biochemical changes associated with obesity may accelerate osteoarthritis beyond the effect of mechanical factors. This study investigated whether metabolic syndrome and its components (visceral obesity, ... -
Metallionenivåer i blod fra pasienter med metall-mot-metall-hofteprotese
(Journal article; Peer reviewed, 2021)Bakgrunn: BHR-protese (Birmingham hip resurfacing) er satt inn i hoften til 445 personer i Norge. Bivirkninger av metallfrigjøring fra metall-mot-metall-leddflater av kobolt-krom-legering kan forekomme. Målet med studien ... -
A method for dierentiating human induced pluripotent stem cells toward functional cardiomyocytes in 96‐well microplates
(Journal article; Peer reviewed, 2020)The capacity of pluripotent stem cells both for self-renewal and to differentiate into any cell type have made them a powerful tool for studying human disease. Protocols for efficient differentiation towards cardiomyocytes ... -
Microarray-based gene expression profiling and DNA copy number variation analysis of temporal fossa arachnoid cysts
(Peer reviewed; Journal article, 2010-02-26)Background Intracranial arachnoid cysts (AC) are membranous sacs filled with CSF-like fluid that are commonly found in the temporal fossa. The majority of ACs are congenital. Typical symptoms are headache, dizziness, and ... -
Microemboli detection in acute ischemic stroke
(Doctoral thesis, 2021-12-10)Microembolic signals (MES) are detectable by transcranial Doppler monitoring and represent small, clinically silent particles in the cerebral circulation. MES are related to increased risk of first or recurrent ischemic ... -
Microemboli-monitoring during the acute phase of ischemic stroke: Is it worth the time?
(Peer reviewed; Journal article, 2010-09-10)Background The prevalence of microembolic signals (MES) during the acute phase of ischemic stroke and its influence on outcome is not well studied. The aim of our study was to determine the prevalence of MES, the different ... -
MicroRNA Alterations and Associated Aberrant DNA Methylation Patterns across Multiple Sample Types in Oral Squamous Cell Carcinoma
(Peer reviewed; Journal article, 2011-11-22)Background: MicroRNA (miRNA) expression is broadly altered in cancer, but few studies have investigated miRNA deregulation in oral squamous cell carcinoma (OSCC). Epigenetic mechanisms are involved in the regulation of .30 ... -
MicroRNA-138 abates fibroblast motility with effect on invasion of adjacent cancer cells
(Journal article; Peer reviewed, 2022-03-17)Background: Recent studies have shown aberrant expression of micro-RNAs in cancer-associated fibroblasts (CAFs). This study aimed to investigate miR-138 dysregulation in CAFs in oral squamous cell carcinoma (OSCC) and its ... -
MicroRNAs as important players and biomarkers in oral carcinogenesis
(Peer reviewed; Journal article, 2015)Oral cancer, represented mainly by oral squamous cell carcinoma (OSCC), is the eighth most common type of human cancer worldwide. The number of new OSCC cases is increasing worldwide, especially in the low-income countries, ... -
MicroRNAs in Differentiation of Embryoid Bodies and the Teratoma Subtype of Testicular Cancer
(Journal article; Peer reviewed, 2022)Background: Testicular germ cell tumours (TGCTs) are the most frequent tumour type among young, adult men. TGCTs can be efficiently treated, but metastases of the teratoma subtype, for which there are no circulating ... -
Microsatellite instability at tetranucleotides (EMAST) in colorectal cancer: clinical relevance, mechanisms and immune markers
(Doctoral thesis, 2020-06-18)Colorectal cancer (CRC) is the second-leading cause of cancer-related death and a global burden in terms of incidence, person-years of life lost and public health costs. About 10-20% of sporadic CRCs develop through a ... -
Microvascular proliferation in luminal Aand basal-like breast cancer subtypes
(Peer reviewed; Journal article, 2015)Aims: The aims of this study were to examine microvessel density (MVD), proliferating MVD (pMVD) and Vascular Proliferation Index (VPI) in basal-like phenotype (BP) and luminal A subtypes of breast cancer and to study their ...