Browsing Department of Clinical Science by Title
Now showing items 597-616 of 2348
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Do environmental effects indexed by parental genetic variation influence common psychiatric symptoms in childhood?
(Journal article; Peer reviewed, 2023)Parental genes may indirectly influence offspring psychiatric outcomes through the environment that parents create for their children. These indirect genetic effects, also known as genetic nurture, could explain individual ... -
Do reduced numbers of plasmacytoid dendritic cells contribute to the aggressive clinical course of COVID-19 in chronic lymphocytic leukaemia?
(Journal article; Peer reviewed, 2022)Infections with SARS-CoV-2 have been unduly severe in patients with haematological malignancies, in particular in those with chronic lymphocytic leukaemia (CLL). Based on a series of observations, we propose that an ... -
Does a history of migraine affect the rate of thrombolysis in young stroke patients?
(Peer reviewed; Journal article, 2013)Background. Migraine is prevalent in young patients and a frequent stroke mimic. To distinguish stroke mimics from true stroke can be difficult, and there is a possibility of misdiagnosing a stroke as a migrainous attack ... -
Does Current Diabetes Technology Improve Metabolic Control? A Cross-Sectional Study on the Use of Insulin Pumps and Continuous Glucose Monitoring Devices in a Nationwide Pediatric Population
(Journal article; Peer reviewed, 2021)Objective To examine the use of multiple daily injections (MDI), insulin pumps, self-measured blood glucose (SMBG), and continuous glucose monitoring (CGM) systems, and their association with glycated hemoglobin (HbA1c), ... -
Does sarcopenia predict change in mobility after hip fracture? A multicenter observational study with one-year follow-up
(Peer reviewed; Journal article, 2018-03-05)Background: Patients with hip fracture frequently have sarcopenia and are at great risk of loss of mobility. We have investigated if sarcopenia predicts change in mobility after hip fracture. Methods: This is a prospective, ... -
Dokumentasjon av farmasøytiske intervensjoner ved reseptekspedisjon i sykehusapotek
(Master thesis, 2019-06-18)Bakgrunn: Gjennom farmasøytkontrollen har farmasøyter en viktig rolle i å sikre riktig legemiddelbruk, ved å avdekke og håndtere problemer knyttet til forskrivning av resepter. De to siste norske studiene på området har ... -
Dominant-negative heterozygous mutations in AIRE confer diverse autoimmune phenotypes
(Journal article; Peer reviewed, 2023)Autoimmune polyendocrine syndrome type 1 (APS-1) is an autosomal recessive disease characterized by severe and childhood onset organ-specific autoimmunity caused by mutations in the autoimmune regulator (AIRE) gene. More ... -
Dose-dependent transcriptional effects of lithium and adverse effect burden in a psychiatric cohort
(Journal article; Peer reviewed, 2022)Lithium is the first-line treatment for bipolar disorder (BD), but there is a large variation in response rate and adverse effects. Although the molecular effects of lithium have been studied extensively, the specific ... -
Double paternal uniparental isodisomy 7 and 15 presenting with Beckwith–Wiedemann spectrum features
(Journal article; Peer reviewed, 2021)Here we describe for the first time double paternal uniparental isodisomy (iUPD) 7 and 15 in a baby boy with features in the Beckwith–Wiedemann syndrome spectrum (BWSp) (placentomegaly, hyperinsulinism, enlarged viscera, ... -
Double-vs single-balloon catheter for induction of labor: Systematic review and individual participant data meta-analysis
(Journal article; Peer reviewed, 2023)Introduction Evidence comparing double-balloon vs single-balloon catheter for induction of labor is divided. We aim to compare the efficacy and safety of double-vs single-balloon catheters using individual participant ... -
Drug adherence in patient group with Parkinson's disease
(Master thesis, 2018-06-29)Background Patients with Parkinson’s disease needs medicines administered frequently to manage their condition and maintain their quality of life. Poor medicine adherence may influence health negatively, and cause an ... -
Drug delivery in pancreatic cancer : Quantitative studies of gemcitabine and sonoporation in patients and cell line models
(Doctoral thesis, 2020-03-06)Background Pancreatic ductal adenocarcinoma (PDAC) has a dismal prognosis due to late stage diagnosis and unresponsiveness to chemotherapies. A dense desmoplastic tumour stroma is considered to represent a barrier against ... -
Drug information in pregnancy. Attitudes and needs among pregnant women and physicians
(Doctoral thesis, 2013-10-25)Background: Drug use in pregnancy is common and both pregnant women and their physicians are in need of appropriate information for decision-making regarding drug therapy. However, uncertainty about the risks of drug use ... -
Durable immune responses after BNT162b2 vaccination in home-dwelling old adults
(Journal article; Peer reviewed, 2023)Objectives Elderly are an understudied, high-risk group vulnerable to severe COVID-19. We comprehensively analyzed the durability of humoral and cellular immune responses after BNT162b2 vaccination and SARS-CoV-2 infection ... -
Duration of elevated heart rate Is an important predictor of exercise-induced troponin elevation
(Journal article; Peer reviewed, 2020)Background The precise mechanisms causing cardiac troponin (cTn) increase after exercise remain to be determined. The aim of this study was to investigate the impact of heart rate (HR) on exercise‐induced cTn increase by ... -
Dynamic differences in dietary polyunsaturated fatty acid metabolism in sputum of COPD patients and controls
(Peer reviewed; Journal article, 2019)Introduction: Disturbances in onset and resolution of inflammation in chronic obstructive pulmonary disease (COPD) are incompletely understood. Dietary polyunsaturated fatty acids (PUFAs) can be converted into lipid mediators ... -
Dynamics of circulating lymphocytes responding to human experimental enterotoxigenic Escherichia coli infection
(Journal article; Peer reviewed, 2023)Enterotoxigenic Escherichia coli (ETEC) is an important cause of children's and travelers’ diarrhea, with no licensed vaccine. This study aimed to explore the role of cellular immunity in protection against human ETEC ... -
The dynamics of nutritional-related blood biomarker and metabolite concentrations during the postprandial and fasting states : And the implications when using nutritional-related biomarkers and metabolites in clinical care and research settings
(Doctoral thesis, 2024-04-05)BAKGRUNN: Vi vet lite om hvordan ernæringsrelaterte biomarkører og metabolitter endrer seg i blodet i postprandiell og fastende tilstand. MÅL: Å undersøke hvordan konsentrasjonen av aminosyrer, en-karbon metabolitter, ... -
Dysfunction of the protein quality control system in neurodegeneration: A study of the co-chaperone and ubiquitin ligase CHIP in vitro and in zebrafish
(Doctoral thesis, 2021-09-15)The C-terminus of Hsc70 interacting protein (CHIP) is a dimeric co-chaperone and E3 ubiquitin ligase encoded by the STIP1 homology and U-box containing protein 1 (STUB1) gene. As a major player in the protein quality control ... -
Dyspnea, lung function and CT findings three months after hospital admission for COVID-19
(Journal article; Peer reviewed, 2021)The long-term pulmonary outcomes of coronavirus disease 2019 (COVID-19) are unknown. We aimed to describe self-reported dyspnoea, quality of life, pulmonary function and chest computed tomography (CT) findings 3 months ...