Blar i Department of Clinical Science på tittel

Viser treff 1366-1385 av 2343

    • Lung cancer on Haugalandet, Norway. A long term follow-up study 

      Skaug, Knut (Doctoral thesis, 2012-06-06)
      Background: Little was known on long term survival, the use of hospital days, symptoms both initially and terminally, and the quality of lung cancer care for the population of the patients with lung cancer in Haugalandet, ...

    • Lung function and bronchial hyperreactivity from 11 to 18 years in children with bronchiolitis in infancy 

      Sørensen, Karen Galta; Øymar, Knut; Dalen, Ingvild; Halvorsen, Thomas; Mikalsen, Ingvild Bruun (Peer reviewed; Journal article, 2020)
      Background: Various trajectories for lung function and bronchial hyper‐reactivity (BHR) from early childhood to adulthood are described, including puberty as a period with excessive lung growth. Bronchiolitis in infancy ...

    • Lung function at term in extremely preterm-born infants: A regional prospective cohort study 

      Bentsen, Mariann; Markestad, Trond; Øymar, Knut; Halvorsen, Thomas (Journal article; Peer reviewed, 2017)
      Objectives: To compare lung function of extremely preterm (EP)-born infants with and without bronchopulmonary dysplasia (BPD) with that of healthy term-born infants, and to determine which perinatal characteristics were ...

    • Lung hyperinflation and functional exercise capacity in patients with COPD - a three-year longitudinal study 

      Aalstad, Linn T.; Hardie, Jon Andrew; Espehaug, Birgitte; Thorsen, Einar; Bakke, Per S.; Eagan, Tomas Mikal; Frisk, Bente (Peer reviewed; Journal article, 2018-12-06)
      Background: Lung hyperinflation contributes to dyspnea, morbidity and mortality in chronic obstructive pulmonary disease (COPD). The inspiratory-to-total lung capacity (IC/TLC) ratio is a measure of lung hyperinflation and ...

    • Machine learning approaches in microbiome research: challenges and best practices 

      Papoutsoglou, Georgios; Tarazona, Sonia; Lopes, Marta B.; Klammsteiner, Thomas; Ibrahimi, Eliana; Eckenberger, Julia; Novielli, Pierfrancesco; Tonda, Alberto; Simeon, Andrea; Shigdel, Rajesh; Béreux, Stéphane; Vitali, Giacomo; Tangaro, Sabina; Lahti, Leo; Temko, Andriy; Claesson, Marcus J.; Berland, Magali (Journal article; Peer reviewed, 2023)
      Microbiome data predictive analysis within a machine learning (ML) workflow presents numerous domain-specific challenges involving preprocessing, feature selection, predictive modeling, performance estimation, model ...

    • Machine learning based on biomarker profiles identifies distinct subgroups of heart failure with preserved ejection fraction 

      Woolley, Rebecca J.; Ceelen, Daan; Ouwerkerk, Wouter; Tromp, Jasper; Figarska, Sylwia M.; Anker, Stefan D.; Dickstein, Kenneth; Filippatos, Gerasimos; Zannad, Faiez; Marco, Metra; Ng, Leong L.; Samani, Nilesh J.; van Veldhuisen, Dirk J; Lang, Chim C.; Lam, Carolyn S.P.; Voors, Adriaan A. (Journal article; Peer reviewed, 2021)
      Aims The lack of effective therapies for patients with heart failure with preserved ejection fraction (HFpEF) is often ascribed to the heterogeneity of patients with HFpEF. We aimed to identify distinct pathophysiologic ...

    • Magnetic Resonance Imaging and Computed Tomography for the Noninvasive Assessment of Arterial Aging: A Review by the VascAgeNet COST Action 

      Bianchini, Elisabetta; Lønnebakken, Mai Tone; Wohlfahrt, Peter; Piskin, Senol; Terentes-Printzios, Dimitrios; Alastruey, Jordi; Guala, Andrea (Journal article; Peer reviewed, 2023)
      Magnetic resonance imaging and computed tomography allow the characterization of arterial state and function with high confidence and thus play a key role in the understanding of arterial aging and its translation into the ...

    • Maintained survival outcome after reducing lymphadenectomy rates and optimizing adjuvant treatment in endometrial cancer 

      Forsse, David Erik; Berg, Hege Fredriksen; Bozickovic, Olivera; Engerud, Hilde Renate; Halle, Mari Kyllesø; Høivik, Erling Andre; Woie, Kathrine; Werner, Henrica Maria Johanna; Haldorsen, Ingfrid S.; Trovik, Jone; Krakstad, Camilla (Journal article; Peer reviewed, 2020)
      Objective: Main controversies in endometrial cancer treatment include the role of lymphadenectomy and optimal adjuvant treatment. We assessed clinical outcome in a population-based endometrial cancer cohort in relation to ...

    • Major increase in microbiota-dependent proatherogenic metabolite TMAO one year after bariatric surgery 

      Trøseid, Marius; Hov, Johannes Espolin Roksund; Nestvold, Torunn Kristin; Thoresen, Hanne; Berge, Rolf Kristian; Svardal, Asbjørn M.; Lappegård, Knut Tore (Journal article; Peer reviewed, 2016)
      Background: Trimethylamine-N-oxide (TMAO) is formed in the liver from trimethylamine (TMA), a product exclusively generated by the gut microbiota from dietary phosphatidylcholine and carnitine. An alternative pathway of ...

    • Making wise decisions for completion thyroidectomies 

      Brun, Vegard Heimly; Brauckhoff, Katrin (Journal article; Peer reviewed, 2022)

    • Malaria prevalence among patients with acute undifferentiated fever in secondary hospitals in India 

      Haanshuus, Christel Gill; Vivek, Rosario; Xena, Deepika; Chandy, Sara; Mathai, Dilip; Manoharan, Anand; Langeland, Nina; Blomberg, Bjørn; Mørch, Kristine (Conference poster, 2014-09-22)

    • Malaria prevalence and performance of diagnostic tests among patients hospitalized with acute undifferentiated fever in Zanzibar 

      Onken, Annette; Haanshuus, Christel Gill; Miraji, Mohammed Khamis; Marijani, Msafiri; Kibwana, Kibwana Omar; Abeid, Khamis Ali; Mørch, Kristine; Reimers, Marianne; Langeland, Nina; Müller, Fredrik; Jenum, Pål; Blomberg, Bjørn (Journal article; Peer reviewed, 2022-02-19)
      Background: Control efforts in Zanzibar reduced the burden of malaria substantially from 2000 to 2015, but re-emergence of falciparum malaria has been observed lately. This study evaluated the prevalence of malaria and ...

    • Management and interpretation of heterogeneous observational data: Using insulin-like growth factor-I data from the NordiNet® International Outcome Study 

      Blankenstein, Oliver; Pedersen, Birgitte Tønnes; Schlumpf, Michael; Andreasen, Arne Haahr; Juliusson, Petur Benedikt (Peer reviewed; Journal article, 2014-12-09)
      Objective. The NordiNet® International Outcome Study (IOS), a large-scale, non-interventional, multi-centre, real-world study of Norditropin® treatment, registers insulin-like growth factor-I (IGF-I) values, as measured ...

    • Managing Contamination and Diverse Bacterial Loads in 16S rRNA Deep Sequencing of Clinical Samples: Implications of the Law of Small Numbers 

      Dyrhovden, Ruben; Rippin, Martin; Øvrebø, Kjell Kåre; Nygaard, Randi Monsen; Ulvestad, Elling; Kommedal, Øyvind (Journal article; Peer reviewed, 2021)
      In this article, we investigate patterns of microbial DNA contamination in targeted 16S rRNA amplicon sequencing (16S deep sequencing) and demonstrate how this can be used to filter background bacterial DNA in diagnostic ...

    • Mapping the expression of an ANK3 isoform associated with bipolar disorder in the human brain 

      Holmgren, Asbjørn; Hansson, Lars; Bjerkaas-Kjeldal, Kristine; Impellizzeri, Agata Antonia Rita; Gilfillan, Gregor; Djurovic, Srdjan; Hughes, Timothy (Journal article; Peer reviewed, 2022)
      The gene ankyrin-3 (ANK3) has been consistently associated with bipolar disorder (BD) in several genome-wide association studies (GWAS). The exact molecular mechanisms underlying this genetic association remain unknown. ...

    • Mapping the human genetic architecture of COVID-19 

      Niemi, Mari E.K.; Karjalainen, Juha; Liao, Rachel G.; Neale, Benjamin M.; Daly, Mark; Ganna, Andrea; Pathak, Gita A.; Andrews, Shea J.; Kanai, Masahiro; Veerapen, Kumar; Fernandez-Cadenas, Israel; Schulte, Eva C.; Striano, Pasquale; Afset, Jan Egil; Solligård, Erik; Damås, Jan Kristian; Risnes, Kari; Bettini, Laura Rachele; Gustad, Lise Tuset; Holter, Jan Cato; Hov, Johannes Espolin Roksund; Karlsen, Tom Hemming; Folseraas, Trine; Holten, Aleksander Rygh; Dyrhol-Riise, Anne Ma; Tonby, Kristian; Lind, Andreas; Müller, Fredrik; Dudman, Susanne Gjeruldsen; Grimsrud, Marit Mæhle; Vadla, May Sissel; Myhre, Ronny; Kildal, Anders Benjamin; Hoff, Dag Arne Lihaug; Muller, Karl Erik; Heggelund, Lars; Bergan, Jonas; Skogen, Vegard (Journal article; Peer reviewed, 2021)
      The genetic make-up of an individual contributes to the susceptibility and response to viral infection. Although environmental, clinical and social factors have a role in the chance of exposure to SARS-CoV-2 and the severity ...

    • Markedsføring av naturmidler- en vurdering 

      Tønnesen, Maria Høyland (Master thesis, 2008-06-02)
      Hensikten med oppgaven var å undersøke og sammenligne markedsføringen av naturmidler i kommunikasjonskanalene apotek, helsekostforretninger, Internett, ukeblad og magasiner. I løpet av ti uker ble det samlet inn annonser, ...

    • Markers of disease activity in COPD: an 8-year mortality study in the ECLIPSE cohort 

      Celli, Bartolome; Locantore, Nicholas; Yates, Julie C.; Bakke, Per S.; Calverley, Peter M.A.; Crim, Courtney; Coxson, Harvey O.; Lomas, David A.; MacNee, William; Miller, Bruce E.; Mullerova, Hana; Rennard, Stephen I.; Silverman, Edwin K.; Wouters, Emiel F.; Tal-Singer, Ruth; Agusti, Alvar; Vestbo, Jørgen (Journal article; Peer reviewed, 2021)
      Rationale There are no validated measures of disease activity in COPD. Since “active” disease is expected to have worse outcomes (e.g. mortality), we explored potential markers of disease activity in patients enrolled in ...

    • Markers of nephropathy in young Fabry disease patients; role of kidney biopsies and functional measurements 

      Tøndel, Camilla (Doctoral thesis, 2013-04-05)
      Backgound: Fabry disease is an X-linked disease affecting glycosphingolipid metabolism due to deficiency of the lysosomal enzyme α-galactosidase. The natural course of the disease is related to progressive accumulation of ...

    • Markers of Subclinical Atherosclerosis in Severe Obesity and One Year after Bariatric Surgery 

      Kovac, Nina; Grymyr, Lisa Marie Dale; Gerdts, Eva; Nadirpour, Saied; Nedrebø, Bjørn Gunnar; Hjertaas, Johannes Just; Matre, Knut; Cramariuc, Dana (Journal article; Peer reviewed, 2022)
      Background: Aortic valve sclerosis (AVS), mitral valve sclerosis (MVS), remodeling of major arteries, and increased pericardial fat are associated with subclinical atherosclerosis. We assessed these markers of atherosclerosis ...