Blar i Department of Clinical Science på tittel

Viser treff 1601-1620 av 2343

    • Outcomes following PDA surgery in extremely preterm born subjects. Focusing on left vocal cord paralysis and associated short- and long-tem outcomes 

      Engeset, Merete Salveson (Doctoral thesis, 2022-06-14)
      Background: Extremely preterm born (EPB) infants are at risk of a range of complications, among them a patent ductus arteriosus (PDA). If a conservative approach does not reduce the cardiopulmonary compromise imposed by ...

    • Outdoor air pollution and hormone-assessed pubertal development in children: Results from the GINIplus and LISA birth cohorts 

      Zhao, Tianyu; Triebner, Kai Philipp; Markevych, Iana; Standl, Marie; Altug, Hicran; de Hoogh, Kees; Schikowski, Tamara; Berdel, Dietrich; Koletzko, Sibylle; Bauer, Carl-Peter; von Berg, Andrea; Nowak, Dennis; Heinrich, Joachim (Journal article; Peer reviewed, 2021)
      Background Air pollution is hypothesized to affect pubertal development. However, the few studies on this topic yielded overall mixed results. These studies did not consider important pollutants like ozone, and none of ...

    • Overcoming addition of phosphoethanolamine to lipid A mediated colistin resistance in Acinetobacter baumannii clinical isolates with colistin–sulbactam combination therapy 

      Srisakul, Sukrit; Wannigama, Dhammika Leshan; Higgins, Paul G.; Hurst, Cameron; Abe, Shuichi; Hongsing, Parichart; Saethang, Thammakorn; Luk-in, Sirirat; Liao, Tingting; Kueakulpattana, Naris; Shein, Aye Mya Sithu; Gan, Lin; Kupwiwat, Rosalyn; Tanasatitchai, Chanikan; Wapeesittipan, Pattama; Phattharapornjaroen, Phatthranit; Badavath, Vishnu Nayak; Leelahavanichkul, Asada; Chatsuwan, Tanittha (Journal article; Peer reviewed, 2022)
      Overcoming colistin-resistant Acinetobacter baumannii (CoR-AB) has become a major concern due to the lack of effective antibiotics. This study aimed to explore the prevalence of CoR-AB clinical isolates in Thailand, their ...

    • Overweight and obesity in children: a study of weight-related anthropometric variables in childhood 

      Brannsether-Ellingsen, Bente (Doctoral thesis, 2015-11-13)

    • OXR1A, a Coactivator of PRMT5 Regulating Histone Arginine Methylation 

      Yang, Mingyi; Lin, Xiaolin; Segers, Filip; Suganthan, Rajikala; Hildrestrand, Gunn Annette; Rinholm, Johanne Egge; Aas, Per Arne; Sousa, Mirta; Holm, Sverre; Bolstad, Nils; Warren, David; Berge, Rolf Kristian; Johansen, Rune Forstrøm; Yndestad, Arne; Kristiansen, Elise; Klungland, Arne; Gomez, Luisa Fernanda Luna; Eide, Lars; Halvorsen, Bente; Aukrust, Pål; Bjørås, Magnar (Journal article; Peer reviewed, 2020)
      Oxidation resistance gene 1 (OXR1) protects cells against oxidative stress. We find that male mice with brain-specific isoform A knockout (Oxr1A−/−) develop fatty liver. RNA sequencing of male Oxr1A−/− liver indicates ...

    • Oxygen concentration in inhaled gas and nitric oxide concentration in exhaled gas. Is nitric oxide concentration in exhaled gas a useful marker for exposure to hyperoxia? 

      Caspersen, Cecilie (Doctoral thesis, 2014-04-10)
      Background: Exposure to partial pressures of oxygen (PO2) higher than 50 kPa may result in toxic effects on the lungs with reduced vital capacity, maximal expiratory flow rates and diffusion capacity. The risk of developing ...

    • p53 protein biosignatures in acute myeloid leukemia 

      Ånensen, Nina (Doctoral thesis, 2006-03-10)
      p53 is a tumor suppressor protein often regarded as the guardian of the genome. It is a highly connected protein involved in many signaling processes in the cell. The inactivation of p53 through genetic mutations in TP53 ...

    • p53 Protein Isoform Profiles in AML: Correlation with Distinct Differentiation Stages and Response to Epigenetic Differentiation Therapy 

      Haaland, Ingvild; Hjelle, Sigrun Margrethe; Reikvam, Håkon; Sulen, André; Ryningen, Anita; McCormack, Emmet; Bruserud, Øystein; Gjertsen, Bjørn Tore (Journal article; Peer reviewed, 2021)
      p53 protein isoform expression has been found to correlate with prognosis and chemotherapy response in acute myeloid leukemia (AML). We aimed to investigate how p53 protein isoforms are modulated during epigenetic ...

    • Pain and pain tolerance in whiplash-associated disorders:A population-based study 

      Myrtveit, Solbjørg Makalani; Skogen, Jens Christoffer; Sivertsen, Børge; Steingrímsdóttir, Ólöf Anna; Stubhaug, Audun; Nielsen, Christopher Sivert (Peer reviewed; Journal article, 2015)
      Background: Pain is a cardinal symptom in individuals with whiplash-associated disorders (WAD). We aimed to compare pain characteristics between individuals with WAD and individuals reporting chronic pain from other causes, ...

    • Paradoxical sinus deceleration during dobutamine stress echocardiography: case series and review of the literature 

      Sulo, Enxhela; Davidsen, Einar Skulstad; Lønnebakken, Mai Tone; Bleie, Øyvind; Saeed, Sahrai (Journal article; Peer reviewed, 2022)
      Background: Dobutamine stress echocardiography is an established diagnostic modality for assessing myocardial ischaemia in patients with known or suspected coronary artery disease. Dobutamine infusion causes dose-dependent ...

    • Parent psychological wellbeing in a single-family room versus an open bay neonatal intensive care unit 

      Tandberg, Bente Silnes; Flacking, Renée; Markestad, Trond Jacob; Grundt, Hege; Moen, Atle (Peer reviewed; Journal article, 2019-11-05)
      Background Studies of parents’ psychological well-being in single-family rooms in neonatal intensive care units have shown conflicting results. Aims To compare emotional distress in the form of depression, anxiety, stress ...

    • Parental anxiety related to referral of childhood heart murmur; an observational/interventional study 

      Bårdsen, Tonje; Sørbye, Mari Hoven; Trønnes, Håvard; Greve, Gottfried; Berg, Ansgar (Peer reviewed; Journal article, 2015-11-21)
      Background: Detection of a heart murmur in healthy children is common, but may generate anxiety among parents. Many parents believe a heart murmur is a sign of heart disease, although the majority of heart murmurs are ...

    • Parental involvement in decision-making about their child's health care at the hospital 

      Aarthun, Antje; Øymar, Knut; Akerjordet, Kristin (Peer reviewed; Journal article, 2018-07-30)
      Aim: To explore parents’ experiences on parental involvement in decision‐making about their child’s health care at the hospital and to identify how health professionals can improve parental involvement. Design: An explorative ...

    • Parental smoking and risk of childhood-onset type 1 diabetes 

      Magnus, Maria Christine; Tapia, German; Olsen, Sjurdur Frodi; Granström, Charlotta; Mårild, Karl Staffan; Ueland, Per Magne; Midttun, Øivind; Svensson, Jannet; Johannesen, Jesper; Skrivarhaug, Torild; Joner, Geir; Njølstad, Pål Rasmus; Størdal, Ketil; Stene, Lars Christian Mørch (Peer reviewed; Journal article, 2018-11)
      Background: A few prospective studies suggest an association between maternal smoking during pregnancy and lower risk of type 1 diabetes. However, the role of unmeasured confounding and misclassification remains unclear. ...

    • Parents’ Attitudes toward Clinical Genetic Testing for Autism Spectrum Disorder—Data from a Norwegian Sample 

      Johannessen, Tor Jarle; Nærland, Terje; Hope, Sigrun; Torske, Tonje; Høyland, Anne Lise; Strohmaier, Jana; Heiberg, Arvid; Rietschel, Marcella; Djurovic, Srdjan; Andreassen, Ole Andreas (Peer reviewed; Journal article, 2017-05-18)
      Clinical genetic testing (CGT) of children with autism spectrum disorder (ASD) may have positive and negative effects. Knowledge about parents’ attitudes is needed to ensure good involvement of caregivers, which is crucial ...

    • Parents’ smoking onset before conception as related to body mass index and fat mass in adult offspring: Findings from the RHINESSA generation study 

      Knudsen, Gerd Toril Mørkve; Dharmage, Shyamali C.; Janson, Christer; Abramson, Michael J.; Benediktsdóttir, Bryndís; Malinovschi, Andrei; Skulstad, Svein Magne; Bertelsen, Randi Jacobsen; Real, Francisco Gomez; Schlünssen, Vivi; Jögi, Nils Oskar; Sánchez-Ramos, José Luis; Holm, Mathias; Garcia-Aymerich, Judith; Forsberg, Bertil; Svanes, Cecilie; Johannessen, Ane (Journal article; Peer reviewed, 2020)
      Emerging evidence suggests that parents’ preconception exposures may influence offspring health. We aimed to investigate maternal and paternal smoking onset in specific time windows in relation to offspring body mass index ...

    • PARP-inhibition reprograms macrophages toward an anti-tumor phenotype 

      Wang, Lin; Wang, Dan; Sonzogni, Olmo; Ke, Shizhong; Wang, Qi; Thavamani, Abhishek; Batalini, Felipe; Stopka, Sylwia A.; Regan, Michael S.; Vandal, Steven; Tian, Shengya; Pinto, Jocelin; Cyr, Andrew M.; Bret-Mounet, Vanessa C.; Baquer, Gerard; Eikesdal, Hans Petter; Yuan, Min; Asara, John M.; Heng, Yujing J.; Bai, Peter; Agar, Nathalie Y.R.; Wulf, Gerburg M. (Journal article; Peer reviewed, 2022)
      Poly(ADP)ribosylation inhibitors (PARPis) are toxic to cancer cells with homologous recombination (HR) deficiency but not to HR-proficient cells in the tumor microenvironment (TME), including tumor-associated macrophages ...

    • Participation in research bronchoscopy: a literature review 

      Martinsen, Einar Marius Hjellestad; Leiten, Elise Orvedal; Bakke, Per S.; Eagan, Tomas Mikal; Grønseth, Rune (Peer reviewed; Journal article, 2016-02-03)
      Bronchoscopy is the preferred method for collecting biological samples from the lower airways of subjects in clinical research. However, ensuring participation in clinical research can be challenging when the research ...

    • Paternal and maternal birthweight and offspring risk of macrosomia at term gestations: A nationwide population study 

      Rasmussen, Svein; Carlsen, Ellen Øen; Linde, Lorentz; Morken, Nils-Halvdan; Håberg, Siri Eldevik; Ebbing, Cathrine (Journal article; Peer reviewed, 2023)
      Background There is a paucity of data on whether parents' macrosomia (birthweight ≥4500 g) status influences the risk of macrosomia in the offspring. The role of maternal overweight in the generational effect of macrosomia ...

    • Paternal and maternal obesity but not gestational weight gain is associated with type 1 diabetes 

      Magnus, Maria Christine; Olsen, Sjurdur Frodi; Granström, Charlotta; Lund-Blix, Nicolai Andre; Svensson, Jannet; Johannesen, Jesper; Fraser, Abigail; Skrivarhaug, Torild; Joner, Geir; Njølstad, Pål Rasmus; Størdal, Ketil; Stene, Lars Christian Mørch (Peer reviewed; Journal article, 2018-02-05)
      Background Our objective was to examine the associations of parental body mass index (BMI) and maternal gestational weight gain with childhood-onset type 1 diabetes. Comparing the associations of maternal and paternal BMI ...