• Spatiotemporal variation in risk of Shigella infection in childhood: a global risk mapping and prediction model using individual participant data 

      Badr, Hamada S; Colston, Josh M; Nguyen, Nhat-Lan H; Chen, Yen Ting; Burnett, Eleanor; Ali, Syed Asad; Rayamajhi, Ajit; Satter, Syed M; Van Trang, Nguyen; Eibach, Daniel; Krumkamp, Ralf; May, Jürgen; Adegnika, Ayola Akim; Manouana, Gédéon Prince; Kremsner, Peter Gottfried; Chilengi, Roma; Hatyoka, Luiza; Debes, Amanda K; Ateudjieu, Jerome; Faruque, Abu S G; Hossain, M Jahangir; Kanungo, Suman; Kotloff, Karen L; Mandomando, Inácio; Nisar, M Imran; Omore, Richard; Sow, Samba O; Zaidi, Anita K M; Lambrecht, Nathalie; Adu, Bright; Page, Nicola; Platts-Mills, James A; Mavacala Freitas, Cesar; Pelkonen, Tuula; Ashorn, Per; Maleta, Kenneth; Ahmed, Tahmeed; Bessong, Pascal; Bhutta, Zulfiqar A; Mason, Carl; Mduma, Estomih; Olortegui, Maribel P; Peñataro Yori, Pablo; Lima, Aldo A M; Kang, Gagandeep; Humphrey, Jean; Ntozini, Robert; Prendergast, Andrew J; Okada, Kazuhisa; Wongboot, Warawan; Langeland, Nina; Moyo, Sabrina John; Gaensbauer, James; Melgar, Mario; Freeman, Matthew; Chard, Anna N; Thongpaseuth, Vonethalom; Houpt, Eric; Zaitchik, Benjamin F; Kosek, Margaret N (Journal article; Peer reviewed, 2023)
      Background Diarrhoeal disease is a leading cause of childhood illness and death globally, and Shigella is a major aetiological contributor for which a vaccine might soon be available. The primary objective of this study ...
    • Species Level Description of the Human Ileal Bacterial Microbiota 

      Villmones, Heidi Cecilie; Haug, Erik Skaaheim; Ulvestad, Elling; Grude, Nils; Stenstad, Tore; Halland, Adrian; Kommedal, Øyvind (Journal article; Peer reviewed, 2018)
      The small bowel is responsible for most of the body’s nutritional uptake and for the development of intestinal and systemic tolerance towards microbes. Nevertheless, the human small bowel microbiota has remained poorly ...
    • Specific depressive symptoms are related with different patterns of alcohol use in community-dwelling older adults 

      Castellanos-Perilla, Nicolás; Borda, Miguel Germán; Cataño, Sara; Giraldo, Salomon; Vik-Mo, Audun Osland; Aarsland, Dag; Rao, Rahul Tony (Journal article; Peer reviewed, 2022)
      Objectives To explore how individual depressive symptoms might contribute to different patterns of alcohol consumption in Colombian older adults living in the community. Methods A Secondary analysis from a nationally ...
    • Speckle tracking derived strain in neonates: planes, layers and drift 

      Khan, Muhammad Umael; Omdal, Tom R.; Matre, Knut; Greve, Gottfried (Journal article; Peer reviewed, 2021)
      The aims of this study was to assess the effect of using a four chamber versus a three plane model on speckle tracking derived global longitudinal strain, the effects of drift compensation, the effect of assessing strain ...
    • Sperm counts and endocrinological markers of spermatogenesis in long-term survivors of testicular cancer 

      Brydøy, Marianne; Fosså, Sophie Dorothea; Klepp, Olbjørn; Bremnes, Roy M.; Wist, Erik; Bjøro, Trine; Wentzel-Larsen, Tore; Dahl, Olav (Journal article; Peer reviewed, 2012)
      Background: The objective of this study was to assess markers of spermatogenesis in long-term survivors of testicular cancer (TC) according to treatment, and to explore correlations between the markers and associations ...
    • Spiral Vein-Graft Technique is a durable therapeutic option for Popliteal Artery Aneurysms 

      Gleditsch, Egil Hafstad; Johnsen, Lydia; Gubberud, Espen Tyse; Hjellestad, Iren Drange (Conference poster, 2021)
    • Spirometry in chronic obstructive pulmonary disease in Norwegian general practice 

      Tollånes, Mette Christophersen; Sjaastad, Geir E.; Aarli, Bernt Bøgvald; Sandberg, Sverre (Journal article; Peer reviewed, 2020)
      Background General practitioners (GPs) in Norway increasingly use spirometry diagnostically as well as in follow up of patients with respiratory complaints, but little is known about their skills and knowledge in this ...
    • Spontaneous Splenic Artery Rupture as the First Symptom of Systemic Amyloidosis 

      Bruserud, Øystein; Tvedt, Tor Henrik Anderson; Ahmed, Aymen B; Vintermyr, Olav Karsten; Hervig, Tor Audun; Guttormsen, Anne Berit; Reikvam, Håkon (Journal article; Peer reviewed, 2021)
      Spontaneous splenic rupture is a life-threatening condition leading to a rapidly progressing hypovolemic shock due to intra-abdominal blood loss, with a mortality rate of about 10%. Spontaneous splenic rupture can be caused ...
    • Spontanrapportering av bivirkninger hos barn i Norge for perioden 1998-2007 

      Hauge, Catrine Pansegrau (Master thesis, 2009-05-19)
      Legemidler har tidligere blitt brukt hos barn, fra 0 tom 17 år, uten at disse har blitt tilstrekkelig testet og/eller mangler formulering og autorisasjon til å bli brukt i denne populasjonen. Et nytt europeisk regulativ ...
    • Sputum microbiota and inflammation at stable state and during exacerbations in a cohort of chronic obstructive pulmonary disease (COPD) patients 

      Tangedal, Solveig; Nielsen, Rune; Aanerud, Marianne; Persson, Louise Jeanette Pauline; Wiker, Harald G; Bakke, Per S.; Hiemstra, Pieter S.; Eagan, Tomas Mikal (Peer reviewed; Journal article, 2019-09-17)
      Background: Exacerbations of chronic obstructive pulmonary disease (COPD) are debilitating events and spur disease progression. Infectious causes are frequent; however, it is unknown to what extent exacerbations are caused ...
    • Stability of glycoprotein gene sequences of herpes simplex virus type 2 from primary to recurrent human infection, and diversity of the sequences among patients attending an STD clinic 

      Haarr, Lars; Nilsen, Arvid E; Knappskog, Per; Langeland, Nina (Peer reviewed; Journal article, 2014-02-06)
      Background: Herpes simplex virus type 2 (HSV-2) is sexually transmitted, leading to blisters and ulcers in the genito-anal region. After primary infection the virus is present in a latent state in neurons in sensory ganglia. ...
    • Stability of glycoprotein gene sequences of herpes simplex virus type 2 from primary to recurrent human infection, and diversity of the sequences among patients attending an STD clinic 

      Haarr, Lars; Nilsen, Arvid E.; Knappskog, Per; Langeland, Nina (Peer reviewed; Journal article, 2014-02-06)
      Background: Herpes simplex virus type 2 (HSV-2) is sexually transmitted, leading to blisters and ulcers in the genito-anal region. After primary infection the virus is present in a latent state in neurons in sensory ganglia. ...
    • Stage 1 hypertension, sex, and acute coronary syndromes during midlife: the Hordaland Health Study 

      Kringeland, Ester Anne; Tell, Grethe S.; Midtbø, Helga Bergljot; Igland, Jannicke; Haugsgjerd, Teresa Risan; Gerdts, Eva (Journal article; Peer reviewed, 2022)
      Aims: Hypertension has been suggested as a stronger risk factor for acute coronary syndromes (ACS) in women than men. Whether this also applies to stage 1 hypertension [blood pressure (BP) 130–139/80–89 mmHg] is not ...
    • Stage-dependent prognostic shift in mismatch repair-deficient tumors: Assessing patient outcomes in stage II and III colon cancer 

      Hestetun, Kjersti Elvestad; Rosenlund, Nina Benedikte; Stanisavljevic, Luka; Dahl, Olav; Myklebust, Mette Pernille (Journal article; Peer reviewed, 2022)
      Introduction: Deficient mismatch repair (dMMR) or high microsatellite instability (MSI-H) is associated with an improved prognosis in colon cancer stage II but poor prognosis in stage IV colon cancer. The clinical significance ...
    • Stage-specific transcriptomic changes in pancreatic α-cells after massive β-cell loss 

      Oropeza, Daniel; Cigliola, Valentina; Romero, Agustín; Chera, Simona; Rodríguez-Seguí, Santiago; Herrera, Pedro L. (Journal article; Peer reviewed, 2021)
      Background Loss of pancreatic insulin-secreting β-cells due to metabolic or autoimmune damage leads to the development of diabetes. The discovery that α-cells can be efficiently reprogrammed into insulin-secreting cells ...
    • Starvation to Glucose Reprograms Development of Neurovascular Unit in Embryonic Retinal Cells 

      Özgümüs, Türküler; Sulaieva, Oksana; Jain, Ruchi; Artner, Isabella; Lyssenko, Valeriya (Journal article; Peer reviewed, 2021)
      Perinatal exposure to starvation is a risk factor for development of severe retinopathy in adult patients with diabetes. However, the underlying mechanisms are not completely understood. In the present study, we shed light ...
    • Stathmin Protein Level, a Potential Predictive Marker for Taxane Treatment Response in Endometrial Cancer 

      Werner, Henrica Maria Johanna; Trovik, Jone; Halle, Mari Kyllesø; Wik, Elisabeth; Akslen, Lars A.; Birkeland, Even; Bredholt, Therese; Tangen, Ingvild Løberg; Krakstad, Camilla; Salvesen, Helga Birgitte (Peer reviewed; Journal article, 2014-02-25)
      Stathmin is a prognostic marker in many cancers, including endometrial cancer. Preclinical studies, predominantly in breast cancer, have suggested that stathmin may additionally be a predictive marker for response to ...
    • Statistical and Machine Learning Techniques in Human Microbiome Studies: Contemporary Challenges and Solutions 

      Moreno-Indias, Isabel; Lahti, Leo; Nedyalkova, Miroslava; Elbere, Ilze; Roshchupkin, Gennady V.; Adilovic, Muhamed; Aydemir, Onder; Bakir-Gungor, Burcu; Carrillo-de Santa Pau, Enrique; D’Elia, Domenica; Desai, Mahesh S.; Falquet, Laurent; Gundogdu, Aycan; Hron, Karel; Klammsteiner, Thomas; Lopes, Marta B.; Marcos-Zambrano, Laura Judith; Marques, Cláudia; Mason, Michael; May, Patrick; Pašić, Lejla; Pio, Gianvito; Pongor, Sándor; Promponas, Vasilis J.; Przymus, Piotr; Saez-Rodriguez, Julio; Sampri, Alexia; Shigdel, Rajesh; Stres, Blaz; Suharoschi, Ramona; Truu, Jaak; Truică, Ciprian-Octavian; Vilne, Baiba; Vlachakis, Dimitrios; Yilmaz, Ercument; Zeller, Georg; Zomer, Aldert L.; Gomez-Cabrero, David; Claesson, Marcus J. (Journal article; Peer reviewed, 2021)
      The human microbiome has emerged as a central research topic in human biology and biomedicine. Current microbiome studies generate high-throughput omics data across different body sites, populations, and life stages. Many ...
    • Steroid receptor coactivators, HER-2 and HER-3 expression is stimulated by tamoxifen treatment in DMBA-induced breast cancer 

      Moi, Line Leonora Haugan; Flågeng, Marianne Hauglid; Gjerde, Jennifer; Madsen, Andre; Røst, Therese Halvorsen; Gudbrandsen, Oddrun Anita; Lien, Ernst Asbjørn; Mellgren, Gunnar (Peer reviewed; Journal article, 2012-06-15)
      Background: Steroid receptor coactivators (SRCs) may modulate estrogen receptor (ER) activity and the response to endocrine treatment in breast cancer, in part through interaction with growth factor receptor signaling ...
    • Steroidogenic factor 1 (NR5A1) induces multiple transcriptional changes during differentiation of human gonadal-like cells 

      Sepponen, Kirsi; Lundin, Karolina; Yohannes, Dawit A.; Vuoristo, Sanna; Balboa, Diego; Poutanen, Matti; Ohlsson, Claes; Hustad, Steinar; Bifulco, Ersilia; Paloviita, Pauliina; Otonkoski, Timo; Ritvos, Olli; Sainio, Kirsi; Tapanainen, Juha S.; Tuuri, Timo (Journal article; Peer reviewed, 2022)
      Nuclear receptor subfamily 5 group A member 1 (NR5A1) encodes steroidogenic factor 1 (SF1), a key regulatory factor that determines gonadal development and coordinates endocrine functions. Here, we have established a stem ...