Blar i Department of Clinical Science på tittel

Viser treff 2128-2147 av 2347

    • Study and correction of defects in of tyrosine hydroxylase, the rate-limiting enzyme in the synthesis of dopamine 

      Tran, Maria Phuong Anh (Master thesis, 2019-06-18)

    • Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function 

      Davies, Gail; Lam, Max; Harris, Sarah E.; Trampush, Joey W.; Luciano, Michelle; Hill, W. David; Hagenaars, Saskia P.; Ritchie, Stuart J.; Marioni, Riccardo E.; Fawns-Ritchie, Chloe; Liewald, David C.M.; Okely, Judith A.; Ahola-Olli, Ari V.; Barnes, Catriona L.K.; Bertram, Lars; Bis, Joshua C.; Burdick, Katherine E.; Christoforou, Andrea; Derosse, Pamela; Djurovic, Srdjan; Espeseth, Thomas; Giakoumaki, Stella; Giddaluru, Sudheer; Gustavson, Daniel E.; Hayward, Caroline; Hofer, Edith; Ikram, M. Arfan; Karlsson, Robert; Knowles, Emma; Lahti, Jari; Leber, Markus; Li, Shuo; Mather, Karen A.; Melle, Ingrid; Morris, Derek; Oldmeadow, Christopher; Palviainen, Teemu; Payton, Antony; Pazoki, Raha; Petrovic, Katja; Reynolds, Chandra A.; Sargurupremraj, Muralidharan; Scholz, Markus; Smith, Jennifer A.; Smith, Albert V.; Terzikhan, Natalie; Thalamuthu, Anbupalam; Trompet, Stella; van der Lee, Sven J.; Ware, Erin B.; Windham, B. Gwen; Wright, Margaret J.; Yang, Jingyun; Yu, Jin; Ames, David; Amin, Najaf; Amouyel, Philippe; Andreassen, Ole Andreas; Armstrong, Nicola J.; Assareh, Amelia A; Attia, John R.; Attix, Deborah; Avramopoulos, Dimitrios; Bennett, David A.; Böhmer, Anne C.; Boyle, Patricia A.; Brodaty, Henry; Campbell, Harry; Cannon, Tyrone D.; Cirulli, Elizabeth T.; Congdon, Eliza; Conley, Emily Drabant; Corley, Janie; Cox, Simon R.; Dale, Anders; Dehghan, Abbas; Dick, Danielle; Dickinson, Dwight; Eriksson, Johan G.; Evangelou, Evangelos; Faul, Jessica D.; Ford, Ian; Freimer, Nelson A.; Gao, He; Giegling, Ina; Gillespie, Nathan A.; Gordon, Scott D.; Gottesman, Rebecca F.; Griswold, Michael E.; Gudnason, Vilmundur; Harris, Tamara B.; Hartmann, Annette M.; Hatzimanolis, Alex; Heiss, Gerardo; Holliday, Elizabeth G.; Joshi, Peter K.; Kähönen, Mika; Kardia, Sharon L.R.; Karlsson, Ida; Kleineidam, Luca; Knopman, David S.; Kochan, Nicole A.; Konte, Bettina; Kwok, John B.; Le Hellard, Stephanie; Lee, Teresa; Lehtimäki, Terho; Li, Shu-Chen; Liu, Tian; Koini, Marisa; London, Edythe; Longstreth, Will T.; Lopez, Oscar L.; Loukola, Anu; Luck, Tobias; Lundervold, Astri; Lundquist, Anders; Lyytikäinen, Leo-Pekka; Martin, Nicholas G.; Montgomery, Grant W.; Murray, Alison D.; Need, Anna C.; Noordam, Raymond; Nyberg, Lars; Ollier, William; Papenberg, Göran; Pattie, Alison; Polasek, Ozren; Poldrack, Russell A.; Psaty, Bruce M.; Reppermund, Simone; Riedel-Heller, Steffi G.; Rose, Richard J.; Rotter, Jerome I.; Roussos, Panos; Rovio, Suvi P.; Saba, Yasaman; Sabb, Fred W.; Sachdev, Perminder S.; Satizabal, Claudia L.; Schmid, Matthias; Scott, Rodney J.; Scult, Matthew A.; Simino, Jeannette; Slagboom, P. Eline; Smyrnis, Nikolaos; Soumaré, Aïcha; Stefanis, Nikos C.; Stott, David J.; Straub, Richard E.; Sundet, Kjetil Søren; Taylor, Adele M.; Taylor, Kent D.; Tzoulaki, Ioanna; Tzourio, Christophe; Uitterlinden, André; Vitart, Veronique; Voineskos, Aristotle N.; Kaprio, Jaakko; Wagner, Michael; Wagner, Holger; Weinhold, Leonie; Wen, K. Hoyan; Widén, Elisabeth; Yang, Qiong; Zhao, Wei; Adams, Hieab H.H.; Arking, Dan E.; Bilder, Robert M.; Bitsios, Panos; Boerwinkle, Eric; Chiba-Falek, Ornit; Corvin, Aiden; De Jager, Philip L.; Debette, Stéphanie; Donohoe, Gary; Elliott, Paul; Fitzpatrick, Annette L.; Gill, Michael; Glahn, David C.; Hägg, Sara; Hansell, Narelle K.; Hariri, Ahmad; Ikram, M. Kamran; Jukema, J. Wouter; Vuoksimaa, Eero; Keller, Matthew C.; Kremen, William S.; Launer, Lenore; Lindenberger, Ulman; Palotie, Aarno; Pedersen, Nancy L.; Pendleton, Neil; Porteous, David J.; Räikkönen, Katri; Raitakari, Olli T.; Ramirez, Alfredo; Reinvang, Ivar; Rudan, Igor; Rujescu, Dan; Schmidt, Reinhold; Schmidt, Helena; Schofield, Peter W.; Schofield, Peter R.; Starr, John M.; Steen, Vidar Martin; Trollor, Julian N.; Turner, Steven T.; Van Duijn, Cornelia M.; Villringer, Arno; Weinberger, Daniel R.; Weir, David R.; Wilson, James F.; Malhotra, Anil; McIntosh, Andrew M.; Gale, Catharine R.; Seshadri, Sudha; Mosley, Thomas H.; Bressler, Jan; Lencz, Todd; Deary, Ian J. (Peer reviewed; Journal article, 2018)
      General cognitive function is a prominent and relatively stable human trait that is associated with many important life outcomes. We combine cognitive and genetic data from the CHARGE and COGENT consortia, and UK Biobank ...

    • A study of TNF pathway activation in schizophrenia and bipolar disorder in plasma and brain tissue 

      Hoseth, Eva Zsuzsanna; Ueland, Thor; Dieset, Ingrid; Birnbaum, Rebecca; Shin, Joo Heon; Kleinman, Joel Edward; Hyde, Thomas Michael; Mørch, Ragni Helene; Hope, Sigrun; Lekva, Tove; Abraityte, Judita Aurelija; Michelsen, Annika; Melle, Ingrid; Westlye, Lars Tjelta; Ueland, Torill; Djurovic, Srdjan; Aukrust, Pål; Weinberger, Daniel R.; Andreassen, Ole Andreas (Peer reviewed; Journal article, 2017-07)
      Objective: A proinflammatory imbalance in the tumor necrosis factor (TNF) system may contribute to the pathogenesis of schizophrenia (SCZ) and bipolar disorders (BDs) and related comorbidities. We investigated the relative ...

    • A study on the effects of serotonin reuptake inhibitors on platelet function in whole blood and platelet concentrates 

      Reikvam, Anne-Grete (Master thesis, 2010-05-19)
      Background: Several studies report that patients who use serotonin reuptake inhibitors (SRIs) to treat depression may have increased risk of bleeding, particularly from the gastrointestinal tract. This may be related to ...

    • Study protocol: Prevalence of low energy availability and its relation to health and performance among female football players 

      Rosenvinge, Jan H; Dasa, Marcus Småvik; Kristoffersen, Morten; Pettersen, Gunn; Sundgot-Borgen, Jorunn; Sagen, Jørn Vegard; Friborg, Oddgeir (Journal article; Peer reviewed, 2022)
      Enduring low energy availability (LEA) is associated with several potentially serious physiological and mental conditions. LEA has been found highly prevalent among female elite athletes within endurance sports, thus ...

    • Studying GABAA Receptors using AII Amacrine Cells in the Rat Retina 

      Trinh, Tuan van (Master thesis, 2018-06-29)
      The cell membrane consists of several membrane receptors, which based on the structure and functions, are typically divided in 3 classes: G protein-coupled receptors, enzyme-linked receptors and ion channel linked receptors, ...

    • Subclinical cardiac organ damage in patients with moderate to severe psoriasis 

      Linde, Anja G; Gerdts, Eva; Tveit, Kåre Steinar; Kringeland, Ester Anne; Midtbø, Helga Bergljot (Journal article; Peer reviewed, 2021)
      We explored the association between subclinical cardiac organ damage (OD) with comorbidities and psoriasis severity in 53 psoriasis patients on infliximab treatment (age 47 ± 15 years, 30% women) and 99 controls without ...

    • Subjective health complaints are not associated with tick bites or antibodies to Borrelia burgdorferi sensu lato in blood donors in western Norway: a cross-sectional study 

      Hjetland, Reidar; Reiso, Harald; Ihlebæk, Camilla; Nilsen, Roy Miodini; Grude, Nils; Ulvestad, Elling (Peer reviewed; Journal article, 2015-07-14)
      Background: There is controversy about chronic health consequences of tick-borne infections, especially Lyme borreliosis. This study aims to assess whether general function, physical fitness and subjective health complaints ...

    • A subset of patients with acute myeloid leukemia has leukemia cells characterized by chemokine responsiveness and altered expression of transcriptional as well as angiogenic regulators 

      Brenner, Annette; Reikvam, Håkon; Bruserud, Øystein (Peer reviewed; Journal article, 2016-05-25)
      Acute myeloid leukemia (AML) is an aggressive and heterogeneous bone marrow malignancy, the only curative treatment being intensive chemotherapy eventually in combination with allogeneic stem cell transplantation. Both the ...

    • Substantial changes in inflammatory and cardiovascular biomarkers in patients with autonomous cortisol secretion 

      Ueland, Grethe Åstrøm; Methlie, Paal; Heie, Anette; Stokland, Ann-Elin Meling; Dahle, Anne Lise; Sævik, Åse Bjorvatn; Løvås, Kristian; Husebye, Eystein Sverre (Journal article; Peer reviewed, 2023)
      Objective To map inflammatory biomarkers in patients with autonomous cortisol secretion (ACS) and overt Cushing syndrome (CS). Method Observational study including serum from prospectively included patients with ACS ...

    • Subtype-specific surface proteins on adipose tissue macrophages and their association to obesity-induced insulin resistance 

      Strand, Kristina; Stiglund, Natalie; Haugstøyl, Martha Eimstad; Kamyab, Seyedeh Zahra; Langhelle, Victoria Puntervold; Dyer, Laurence; Busch, Christian; Cornillet, Martin; Hjellestad, Iren Drange; Nielsen, Hans Jørgen; Njølstad, Pål Rasmus; Mellgren, Gunnar; Björkström, Niklas K.; Fernø, Johan (Journal article; Peer reviewed, 2022)
      A chronic low-grade inflammation, originating in the adipose tissue, is considered a driver of obesity-associated insulin resistance. Macrophage composition in white adipose tissue is believed to contribute to the pathogenesis ...

    • Supporting safe medicines transition for residents entering care homes 

      Kandiah, Janani (Master thesis, 2021-05-20)

    • Suppression of bile acid synthesis as a tipping point in the disease course of primary sclerosing cholangitis 

      Braadland, Peder Rustøen; Schneider, Kai Markus; Bergquist, Annika; Molinaro, Antonio; Lövgren-Sandblom, Anita; Henricsson, Marcus; Karlsen, Tom Hemming; Vesterhus, Mette Nåmdal; Trautwein, Christian; Hov, Johannes Espolin Roksund; Marschall, Hanns-Ulrich (Journal article; Peer reviewed, 2022)
      Background & Aims: Farnesoid X receptor (FXR) agonists and fibroblast growth factor 19 (FGF19) analogues suppress bile acid synthesis and are being investigated for their potential therapeutic efficacy in cholestatic liver ...

    • Surgical Treatment of Severe Bowel Obstruction as a Rare Complication Following Allogenic Hematopoietic Stem Cell Transplantation 

      Reikvam, Håkon; Tvedt, Tor Henrik Anderson; Johansen, Silje; Setran, Hege Aase; Havre, Roald Flesland (Journal article, 2020)
      Gastrointestinal graft-versus-host disease (GVHD) and cytomegalovirus (CMV) disease are common complications occurring after allogeneic hematopoietic stem cell transplantation (allo-HSCT), and contribute to a high degree ...

    • A survey of surgical team members' perceptions of near misses and attitudes towards Time Out protocols 

      Haugen, Arvid Steinar; Murugesh, Shamini; Haaverstad, Rune; Eide, Geir Egil; Søfteland, Eirik (Peer reviewed; Journal article, 2013-10-09)
      Background: Medical errors are inherently of concern in modern health care. Although surgical errors as incorrect surgery (e.g., wrong patient, wrong site, or wrong procedure) are infrequent, they are devastating events ...

    • A survey of total IgE reference intervals reported by Scandinavian and British medical laboratories – a need for harmonisation 

      Vinnes, Erik Wilhelm; Sletten, Ida Sofie Karlsen; Alnæs, Marie Bjørbak; Storaas, Torgeir; Aarsand, Aasne Karine (Journal article; Peer reviewed, 2023)
      Objectives There appears to be marked discrepancies between total IgE reference intervals (RIs) in use by many laboratories and those recommended by published studies. The aim of this study was therefore to review total ...

    • Survival According to Primary Tumor Location, Stage, and Treatment Patterns in Locoregional Gastroenteropancreatic High-grade Neuroendocrine Carcinomas 

      Dasari, Arvind; Shen, Chan; Devabhaktuni, Anjali; Nighot, Ruda; Sorbye, Halfdan (Journal article; Peer reviewed, 2022)
      Background: Although the gastrointestinal tract (including the pancreas, gastroenteropancreatic (GEP) is the most common site for extrapulmonary neuroendocrine carcinoma (NEC), the current treatment patterns of locoregional ...

    • Survival after aortic root replacement with a stentless xenograft is determined by patient characteristics 

      Dagnegård, Hanna H.; Bekke, Kirstine; Kolseth, Solveig Moss; Glaser, Natalie; Wallén, Christoffer; El-Hamamsy, Ismail; Vidisson, Kristjan O.; Lie, Asbjørn Sigstad; Valentin, Jan; Sartipy, Ulrik; Haaverstad, Rune; Vanky, Farkas; Lefebvre, Laurence; Gudbjartsson, Tomas; Johnsen, Søren P.; Søndergaard, Lars; Thyregod, Gustav H.; Lund, Jens T.; Ihlemann, Nikolaj; Smerup, Morten H. (Journal article; Peer reviewed, 2021)
      Objectives Our objective was to examine intermediate-term survival and reinterventions in unselected patients, stratified according to indication, who received a Freestyle (Medtronic Inc, Minneapolis, Minn) bioprosthesis ...

    • Survival and costs of colorectal cancer treatment and effects of changing treatment strategies: a model approach 

      Joranger, Pål; Nesbakken, Arild; Sorbye, Halfdan; Hoff, Geir; Oshaug, Arne; Aas, Eline (Peer reviewed; Journal article, 2020)
      New and emerging advances in colorectal cancer (CRC) treatment combined with limited healthcare resources highlight the need for detailed decision-analytic models to evaluate costs, survival and quality-adjusted life years. ...

    • Survival and death causes of patients with giant cell arteritis in Western Norway 1972-2012: a retrospective cohort study 

      Brekke, Lene Kristin; Fevang, Bjørg-Tilde Svanes; Diamantopoulos, Andreas P; Assmus, Jörg; Esperø, Elisabet Langseth; Gjesdal, Clara Gram (Peer reviewed; Journal article, 2019-06-25)
      Background: Our objective was to determine the survival and causes of death in a large and well-characterized cohort of patients with giant cell arteritis (GCA). Methods: This is a hospital-based, retrospective, observational ...