Blar i Department of Clinical Science på tittel
Viser treff 280-299 av 2343
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Cardiac arrest as a reportable condition: A cohort study of the first 6 years of the Norwegian out-of-hospital cardiac arrest registry
(Journal article; Peer reviewed, 2020)Objectives The Norwegian Cardiac Arrest Registry (NorCAR) was established in 2013 when cardiac arrest became a mandatory reportable condition. The aim of this cohort study is to describe how the world’s first mandatory, ... -
Cardiac Function and Early Risk Markers for Cardiovascular Disease in Children and Young Adults Surviving Severe Childhood Disease
(Doctoral thesis, 2023-11-03)Sammendrag på norsk Bakgrunn Prosessene som ligger bak utvikling av hjerte-kar sykdom starter tidlig i livet og er avhengig av antall risikofaktorer og debuttidspunkt av disse. Noen grupper er mer utsatt for hjerte-kar ... -
Cardiac magnetic resonance imaging of myocardial mass and fibrosis in primary aldosteronism
(Peer reviewed; Journal article, 2018-03)Background: Primary aldosteronism (PA) is associated with increased cardiovascular morbidity, presumably due to left ventricular (LV) hypertrophy and fibrosis. However, the degree of fibrosis has not been extensively ... -
Cardiac magnetic resonance imaging of myocardial mass and fibrosis in primary aldosteronism
(Peer reviewed; Journal article, 2018-03)Background Primary aldosteronism (PA) is associated with increased cardiovascular morbidity, presumably due to left ventricular (LV) hypertrophy and fibrosis. However, the degree of fibrosis has not been extensively studied. ... -
Cardiac morphology in neonates with fetal growth restriction
(Journal article; Peer reviewed, 2023)Objective: Assess effects of fetal growth restriction (FGR) on cardiac modelling in premature and term neonates. Study design: Prospective echocardiographic study of a cohort of FGR neonates (n = 21) and controls (n = 41) ... -
Cardiac organ damage in systemic hypertension: Impact of gender, etiology, and comorbidities
(Doctoral thesis, 2024-03-15)Bakgrunn: Ukontrollert systemisk hypertensjon fører til økt risiko for kardiovaskulær sykdom og død både ved essensiell og sekundær hypertensjon. Den økte risikoen skyldes i stor grad utvikling av strukturelle og funksjonelle ... -
Cardiac rehabilitation participation within 6 months of discharge in 37 136 myocardial infarction survivors: a nationwide registry study
(Journal article; Peer reviewed, 2023) -
Cardiac Resynchronization Therapy (CRT): Patient Selection and Guideline Adherence : An Analysis of CRT Practice in Europe Based on the European Society of Cardiology CRT Survey II with 11088 patients in 42 countries.
(Doctoral thesis, 2020-09-04)Background/Aims Cardiac Resynchronization Therapy (CRT) reduces morbidity and mortality in patients with heart failure and electrical dyssynchrony. Recommendations for which patients should receive a CRT device are outlined ... -
Cardiac Troponin Assays With Improved Analytical Quality: A Trade-Off Between Enhanced Diagnostic Performance and Reduced Long-Term Prognostic Value
(Journal article; Peer reviewed, 2020)Background Cardiac troponin (cTn) permits early rule‐out/rule‐in of patients admitted with possible non–ST‐segment–elevation myocardial infarction. In this study, we developed an admission and a 0/1 hour rule‐out/rule‐in ... -
Cardiac troponin measurement at the point of care: educational recommendations on analytical and clinical aspects by the IFCC Committee on Clinical Applications of Cardiac Bio-Markers (IFCC C-CB)
(Journal article; Peer reviewed, 2023)The International Federation of Clinical Chemistry and Laboarator Medicine (IFCC) Committee on Clinical Applications of Cardiac Bio-Markers (C-CB) has provided evidence-based educational resources to aid and improve the ... -
Cardiometabolic risk factors differ among adolescents with obesity in three European countries - a cross sectional study
(Peer reviewed; Journal article, 2018-03)Aim: We aimed to compare modifiable cardiometabolic risk factors among treatment‐seeking adolescents with obesity in Italy, Germany and Norway. Methods: This retrospective, registry‐based, cross‐sectional cohort study ... -
Cardiotoxicity of Doxorubicin. A Study of Methods and Protective Interventions in Rat Models
(Doctoral thesis, 2015-03-13)Introduction: The clinical use of anthracyclines, like doxorubicin, is a double-edged sword. On one side, anthracyclines play an undisputed key role in the treatment of many neoplastic diseases. On the other side; ... -
Cardiovascular organ damage in relation to hypertension status in patients with ankylosing spondylitis
(Journal article; Peer reviewed, 2023)Purpose Hypertension is a major cardiovascular (CV) risk factor in ankylosing spondylitis (AS) patients. Less is known about the prevalence of CV organ damage in relation to hypertension status in AS patients. Materials ... -
Cardiovascular risk markers in aortic valve stenosis : Insights in peak systolic left ventricular function, ejection dynamics and obesity
(Doctoral thesis, 2020-12-04)Background: Aortic valve stenosis (AS) is the most prevalent valvular heart disease requiring valvular intervention. With no pharmacological treatment available, optimal management requires detection of early left ventricular ... -
The carnitine-butyrobetaine-TMAO pathway after cardiac transplant: Impact on cardiac allograft vasculopathy and acute rejection
(Peer reviewed; Journal article, 2019)BACKGROUND: Alterations in the partly microbiota-dependent carnitine–γ-butyrobetaine (γBB)–trimethylamine N-oxide (TMAO) pathway have been linked to the progression of heart failure and atherosclerotic disease. We evaluated ... -
Carvedilol-enriched cold oxygenated blood cardioplegia improves left ventricular diastolic function after weaning from cardiopulmonary bypass
(Peer reviewed; Journal article, 2016-08)Objectives: To investigate whether adding carvedilol, a nonselective β- and selective α1-receptor blocking agent with antioxidant properties, to oxygenated blood cardioplegia improves myocardial function after weaning from ... -
Casein Kinase 2 (CK2): A Possible Therapeutic Target in Acute Myeloid Leukemia
(Journal article; Peer reviewed, 2023)The protein kinase CK2 (also known as casein kinase 2) is one of the main contributors to the human phosphoproteome. It is regarded as a possible therapeutic strategy in several malignant diseases, including acute myeloid ... -
Causal Analysis of World Health Organization's Surgical Safety Checklist Implementation Quality and Impact on Care Processes and Patient Outcomes: Secondary Analysis From a Large Stepped Wedge Cluster Randomized Controlled Trial in Norway
(Peer reviewed; Journal article, 2019)Objective: We hypothesize that high-quality implementation of the World Health Organization's Surgical Safety Checklist (SSC) will lead to improved care processes and subsequently reduction of peri- and postoperative ... -
CD24-targeted fluorescence imaging in patient-derived xenograft models of high-grade serous ovarian carcinoma
(Journal article; Peer reviewed, 2020)Background The survival rate of patients with advanced high-grade serous ovarian carcinoma (HGSOC) remains disappointing. Clinically translatable orthotopic cell line xenograft models and patient-derived xenografts (PDXs) ... -
CD24-targeted intraoperative fluorescence image-guided surgery leads to improved cytoreduction of ovarian cancer in a preclinical orthotopic surgical model
(Journal article; Peer reviewed, 2020)Background The completeness of resection is a key prognostic indicator in patients with ovarian cancer, and the application of tumour-targeted fluorescence image-guided surgery (FIGS) has led to improved detection of ...