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    • Exercise training and high-sensitivity cardiac troponin T in patients with heart failure with reduced ejection fraction 

      Koppen, Elias; Omland, Torbjørn; Larsen, Alf Inge; Karlsen, Trine; Linke, Axel; Prescott, Eva Irene Bossano; Halle, Martin; Dalen, Håvard; Delagardelle, Charles; Hole, Torstein; van Craenenbroeck, Emeline M.; Beckers, Paul; Ellingsen, Øyvind; Feiereisen, Patrick; Valborgland, Torstein; Videm, Vibeke (Journal article; Peer reviewed, 2021)
      Aims Whether an exercise training intervention is associated with reduction in long-term high-sensitivity cardiac troponin T (hs-cTnT) concentration (a biomarker of subclinical myocardial injury) in patients with heart ...

    • Exercise Training in Duchenne Muscular Dystrophy: A Systematic Review and Meta-Analysis 

      Hammer, Stian; Toussaint, Michel; Vollsæter, Maria; Tvedt, Marianne Nesbjørg; Røksund, Ola Drange; Reychler, Gregory; Lund, Hans; Andersen, Tiina Maarit (Journal article; Peer reviewed, 2022)
      Objective: To evaluate the effects and safety of exercise training, and to determine the most effective exercise intervention for people with Duchenne muscular dystrophy. Exercise training was compared with no training, ...

    • Exercise-induced laryngeal obstruction (EILO) in athletes: a narrative review by a subgroup of the IOC Consensus on 'acute respiratory illness in the athlete' 

      Clemm, Hege Synnøve Havstad; Olin, J Tod; McIntosh, Cameron; Schwellnus, Martin; Sewry, Nicola; Hull, James H.; Halvorsen, Thomas (Journal article; Peer reviewed, 2022)
      Exercise-induced laryngeal obstruction (EILO) is caused by paradoxical inspiratory adduction of laryngeal structures during exercise. EILO is an important cause of upper airway dysfunction in young individuals and athletes, ...

    • Exercise-induced laryngeal obstruction in athletes treated with inspiratory muscle training 

      Sandnes, Astrid; Andersen, Tiina Maarit; Clemm, Hege Synnøve Havstad; Hilland, Magnus; Vollsæter, Maria; Heimdal, John-Helge; Eide, Geir Egil; Halvorsen, Thomas; Røksund, Ola Drange (Peer reviewed; Journal article, 2019-01-18)
      Background Exercise-induced laryngeal obstruction (EILO) is common in athletes and presents with dyspnoea, chest tightness, inspiratory stridor and sometimes panic reactions. The evidence for conservative treatment is weak, ...

    • Exercise-induced Laryngeal Obstruction: Protocol for a Randomized Controlled Treatment Trial 

      Clemm, Hege Synnøve Havstad; Røksund, Ola Drange; Andersen, Tiina Maarit; Heimdal, John-Helge; Karlsen, Tom; Hilland, Magnus; Fretheim-Kelly, Zoe; Hufthammer, Karl Ove; Sandnes, Astrid; Hjelle, Sigrun Margrethe; Vollsæter, Maria; Halvorsen, Thomas (Journal article; Peer reviewed, 2022)
      Background: Exercise-induced laryngeal obstruction (EILO) is a common cause of exertional breathing problems in young individuals, caused by paradoxical inspiratory adduction of laryngeal structures, and diagnosed by ...

    • Exhaled nitric oxide is related to atopy, but not asthma in adolescents with bronchiolitis in infancy 

      Mikalsen, Ingvild Bruun; Halvorsen, Thomas; Øymar, Knut (Peer reviewed; Journal article, 2013-11-17)
      Background: The fraction of exhaled nitric oxide (FeNO) has been suggested as a non-invasive marker of eosinophilic inflammation in asthma, but lately rather as a biomarker of atopy than of asthma itself. Asthma after ...

    • Exogenous female sex steroids may reduce lung ageing after menopause: A 20-year follow-up study of a general population sample (ECRHS) 

      Triebner, Kai; Accordini, Simone; Calciano, Lucia; Johannessen, Ane; Benediktsdóttir, Bryndís; Bifulco, Ersilia; Demoly, Pascal; Dharmage, Shyamali C.; Franklin, Karl A.; Garcia-Aymerich, Judith; Gullón Blanco, José Antonio; Heinrich, Joachim; Holm, Mathias; Jarvis, Debbie; Jõgi, Rain; Lindberg, Eva; Martínez-Moratalla, Jesús; Muniozguren Agirre, Nerea; Pin, Isabelle; Probst-Hensch, Nicole; Raherison, Chantal; Sánchez-Ramos, José Luis; Schlünssen, Vivi; Svanes, Cecilie; Hustad, Simon Steinar; Leynaert, Bénédicte; Gomez Real, Francisco (Peer reviewed; Journal article, 2019)
      Objectives: Menopause involves hypoestrogenism, which is associated with numerous detrimental effects, including on respiratory health. Hormone replacement therapy (HRT) is often used to improve symptoms of menopause. The ...

    • Exome chip analyses in adult attention deficit hyperactivity disorder 

      Zayats, Tetyana; Jacobsen, Kaya Kvarme; Kleppe, Rune; Jacob, CP; Kittel-Schneider, Sarah; Ribases, Marta; Ramos-Quiroga, JA; Richarte, Vanesa; Casas, M; Mota, NR; Grevet, EH; Klein, M; Corominas, J; Bralten, Janita; Galesloot, T; Vasquez, AA; Herms, S; Forstner, AJ; Larsson, H; Breen, G; Asherson, P; Gross-Lesch, Silke; Lesch, KP; Cichon, Sven; Gabrielsen, Maiken Elvestad; Holmen, Oddgeir Lingaas; Bau, CH; Buitelaar, Jan; Kiemeney, L; Faraone, Stephen V.; Cormand, B; Franke, Barbara; Reif, Andreas; Haavik, Jan; Johansson, Stefan (Peer reviewed; Journal article, 2016)
      Attention-deficit/hyperactivity disorder (ADHD) is a highly heritable childhood-onset neuropsychiatric condition, often persisting into adulthood. The genetic architecture of ADHD, particularly in adults, is largely unknown. ...

    • Experimental Infection of Human Volunteers with the Heat-Stable Enterotoxin-Producing Enterotoxigenic Escherichia coli Strain TW11681 

      Sakkestad, Sunniva Todnem; Steinsland, Hans; Skrede, Steinar; Kleppa, Elisabeth; Lillebø, Kristine; Sævik, Marianne; Søyland, Hanne; Heien, Astrid Rykkje; Tellevik, Marit Gjerde; Barry, Eileen M.; Sommerfelt, Halvor; Hanevik, Kurt (Peer reviewed; Journal article, 2019-06-22)
      Infection with enterotoxigenic Escherichia coli (ETEC) producing the heat-stable enterotoxin (ST) is one of the most important causes of childhood diarrhoea in low- and middle-income countries. Here, we undertook a controlled ...

    • An expert consensus on the recommendations for the use of biomarkers in Fabry disease 

      Burlina, Allesandro; Brand, Eva; Hughes, Derralynn A.; Kantola, Ilkka; Krämer, Johannes; Nowak, Albina; Tøndel, Camilla; Wanner, Christoph; Spada, Marco (Journal article; Peer reviewed, 2023)
      Fabry disease is an X-linked lysosomal storage disorder caused by the accumulation of glycosphingolipids in various tissues and body fluids, leading to progressive organ damage and life-threatening complications. Phenotypic ...

    • Expert opinion of mediastinal lymph node positions from an intrabronchial view 

      Roth, Kjetil; Eagan, Tomas; Hardie, Jon (Peer reviewed; Journal article, 2016-01-22)
      Background The knowledge of the mediastinal lymph node positions from an intrabronchial view was important for conventional transbronchial needle aspiration (TBNA). The introduction of endobronchial ultrasound guided ...

    • Exploration of Cellular Signaling Patterns for the Stratification of Patients with Rheumatoid Arthritis 

      Bader, Lucius (Doctoral thesis, 2020-09-16)
      Introduction: Rheumatoid arthritis (RA) is a chronic inflammatory disease, characterized by synovial inflammation that, if not treated early and efficiently, causes joint damage. The proinflammatory cytokine tumor necrosis ...

    • Exploration of the Cellular Microenvironment in Minor Salivary Glands of Primary Sjögren's Patients by Imaging Mass Cytometry 

      Helgesen, Ylva Bratterud (Master thesis, 2022-05-20)

    • Exploratory analyses on the effect of time since last meal on concentrations of amino acids, lipids, one-carbon metabolites, and vitamins in the Hordaland Health Study 

      Anfinsen, Åslaug Matre; Rosendahl-Riise, Hanne; Nygård, Ottar Kjell; Tell, Grethe S.; Ueland, Per Magne; Ulvik, Arve; McCann, Adrian; Dierkes, Jutta; Lysne, Vegard (Journal article; Peer reviewed, 2023)
      Purpose Dietary intake may have pronounced effects on circulating biomarker concentrations. Therefore, the aim was to provide a descriptive overview of serum metabolite concentrations in relation to time since last meal, ...

    • Exploring and redefining Autoimmune polyendocrine syndrome type 1 

      Bruserud, Øyvind (Doctoral thesis, 2019-02-08)
      Autoimmune polyendocrine syndrome type 1 (APS-1) is a rare, monogenic, childhood-onset disorder caused by mutations in the autoimmune regulator (AIRE) gene. Multi-organ autoimmune disease and chronic mucocutaneous candidiasis ...

    • Exploring lithium's transcriptional mechanisms of action in bipolar disorder: a multi-step study 

      Akkouh, Ibrahim; Skrede, Silje; Holmgren, Asbjørn; Ersland, Kari Merete; Hansson, Lars Johan Axel; Bahrami, Shahram; Andreassen, Ole Andreas; Steen, Vidar Martin; Djurovic, Srdjan; Hughes, Timothy (Peer reviewed; Journal article, 2019)
      Lithium has been the first-line treatment for bipolar disorder (BD) for more than six decades. Although the molecular effects of lithium have been studied extensively and gene expression changes are generally believed to ...

    • Exploring protocol bias in airway microbiome studies: one versus two PCR steps and 16S rRNA gene region V3 V4 versus V4 

      Drengenes, Christine; Eagan, Tomas Mikal; Haaland, Ingvild; Wiker, Harald G; Nielsen, Rune (Journal article; Peer reviewed, 2021)
      Background Studies on the airway microbiome have been performed using a wide range of laboratory protocols for high-throughput sequencing of the bacterial 16S ribosomal RNA (16S rRNA) gene. We sought to determine the ...

    • Exploring the boundaries of precision haemato-oncology : The case of FLT3 length mutated acute myeloid leukaemia 

      Engen, Caroline Benedicte Nitter (Doctoral thesis, 2020-02-14)
      This dissertation explores the astounding biological heterogeneity of acute myeloid leukaemia (AML). In three research papers, we study FLT3 length mutated (LM) AML to contribute to the characterisation of genetic diversity ...

    • Exploring the Patient Perspective of Bone Sarcoma Survivors Who Have Undergone Particle Radiotherapy Abroad 

      Fauske, Lena; Jebsen, Nina Louise; Bondevik, Hilde; Bruland, Øyvind (Journal article; Peer reviewed, 2023)
      Background/Aim: Sarcoma patients’ experiences of their health-related quality of life and late effects following particle therapy are sparse. Such knowledge is essential to optimize treatment compliance and follow-up care ...

    • Exploring the Wnt signaling pathway in schizophrenia and bipolar disorder 

      Hoseth, Eva Zsuzsanna; Krull, Florian; Dieset, Ingrid; Mørch, Ragni Helene; Hope, Sigrun; Gardsjord, Erlend Strand; Steen, Nils Eiel; Melle, Ingrid; Brattbakk, Hans-Richard; Steen, Vidar Martin; Aukrust, Pål; Djurovic, Srdjan; Andreassen, Ole Andreas; Ueland, Thor (Peer reviewed; Journal article, 2018)
      The Wnt signaling pathway plays a crucial role in neurodevelopment and in regulating the function and structure of the adult nervous system. Schizophrenia (SCZ) and bipolar disorder (BD) are severe mental disorders with ...