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Female sex hormones and symptoms of obstructive sleep apnea in European women of a population-based cohort
(Journal article; Peer reviewed, 2022)Background The prevalence of obstructive sleep apnea is higher in women after menopause. This is suggested to be a result of an altered sex hormone balance but has so far not been confirmed in a population-based ... -
Females report higher postoperative pain scores than males after ankle surgery
(Peer reviewed; Journal article, 2016-07)Objectives: The majority of patients experience moderate-to-intense pain following ankle surgery. Early, adequate treatment of postoperative pain is desirable for optimal pain relief, which in turn may facilitate optimal ... -
Feminizing adrenal tumor identified by plasma steroid profiling
(Journal article; Peer reviewed, 2021)Feminizing estrogen-secreting adrenocortical carcinomas (ACCs) are exceedingly rare and carry a poor prognosis. The most common presenting trait is gynecomastia, but enlarged breasts are also a frequent clinical finding ... -
Fetal size in the second trimester is associated with the duration of pregnancy, small fetuses having longer pregnancies
(Peer reviewed; Journal article, 2008-07-16)Background: Conventionally, the pregnancy duration is accepted to be 280–282 days. Fetuses determined by ultrasound biometry to be small in early pregnancy, have an increased risk of premature birth. We speculate that the ... -
Fetal Superior Vena Cava Blood Flow and Its Fraction of Cardiac Output: A Longitudinal Ultrasound Study in the Second Half of Pregnancy
(Journal article; Peer reviewed, 2021)Introduction: In the fetus, a large proportion of the superior vena cava blood flow (QSVC) comes from the brain. To provide the possibility of using this blood flow as a representation of fetal brain circulation, we aimed ... -
Fever in the tropics: aetiology and case-fatality - a prospective observational study in a tertiary care hospital in South India
(Peer reviewed; Journal article, 2013-07-30)Background: The objective of this study was to describe aetiology and case fatality of fever among inpatients in a tertiary care hospital in South India. Methods: This was an observational, prospective study conducted in ... -
Fine mapping of the major histocompatibility complex (MHC) in myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) suggests involvement of both HLA class I and class II loci
(Journal article; Peer reviewed, 2021)The etiology of myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) is unknown, but involvement of the immune system is one of the proposed underlying mechanisms. Human leukocyte antigen (HLA) associations are ... -
Finite element analysis of mitral valve annuloplasty in Barlow's disease
(Journal article; Peer reviewed, 2022)Barlow’s Disease affects the entire mitral valve apparatus causing mitral regurgitation. Standard annuloplasty procedures lead to an average of 55% annular area reduction of the end diastolic pre-operative annular area in ... -
First identification of bla NDM-5 producing Escherichia coli from neonates and a HIV infected adult in Tanzania
(Journal article; Peer reviewed, 2022)Introduction. Carbapenem-resistant members of the family Enterobacteriaceae are emerging as a global public-health threat and cause substantial challenges in clinical practice. Gap Statement. There is a need for increased ... -
First in-mouse development and application of a surgically relevant xenograft model of ovarian carcinoma
(Peer reviewed; Journal article, 2014-03-04)Purpose: Preclinical models of epithelial ovarian cancer have not been exploited to evaluate the clinical standard combination therapy of surgical debulking with follow-up chemotherapy. As surgery is critical to patient ... -
The first vanE-type vancomycin resistant Enterococcus faecalis isolates in Norway – phenotypic and molecular characteristics
(Journal article; Peer reviewed, 2023)Objectives We aimed to characterize the vanE cluster and its genetic support in the first Norwegian vanE-type isolates and assess genetic relatedness to other vanE isolates. Methods Two vanE-type vancomycin resistant ... -
Fish oil and krill oil differentially modify the liver and brain lipidome when fed to mice
(Peer reviewed; Journal article, 2015-08-11)Background: Marine food is an important source of omega-3 fatty acids with beneficial health effects. Oils from marine organisms have different fatty acid composition and differ in their molecular composition. Fish oil ... -
Fish oil and krill oil supplementations differentially regulate lipid catabolic and synthetic pathways in mice
(Peer reviewed; Journal article, 2014-04-27)Background: Marine derived oils are rich in long-chain polyunsaturated omega-3 fatty acids, in particular eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), which have long been associated with health promoting ... -
A fish protein hydrolysate alters fatty acid composition in liver and adipose tissue and increases plasma carnitine levels in a mouse model of chronic inflammation
(Peer reviewed; Journal article, 2013-10-07)Background: There is growing evidence that fish protein hydrolysate (FPH) diets affect mitochondrial fatty acid metabolism in animals. The aim of the study was to determine if FPH could influence fatty acid metabolism and ... -
Fitness in fatness : Associations with cardiovascular risk factors and subclinical disease
(Doctoral thesis, 2019-05-24)Background: Fitness may influence cardiovascular (CV) health in obesity. We explored the impact of fitness on CV risk factors and prevalent subclinical CV disease in overweight and obese women and men without known CV ... -
Flow cytometry based analyses as a tool in biomarker discovery for patient stratification in primary Sjögren’s syndrome
(Doctoral thesis, 2017-03-09)Primary Sjögren’s syndrome (pSS) is a systemic autoimmune disease characterized by lymphocytic infiltrates of exocrine glands, notably the salivary and lacrimal glands combined with immune-mediated glandular destruction. ... -
Flt3 receptor tyrosine kinase in AML and its modulation of the p53/Hdm2/Bcl-2 pathway
(Doctoral thesis, 2007-09-06)Acute myeloid leukemia (AML) is an aggressive disease with a poor overall survival rate. The most frequent mutations associated with AML are internal tandem duplications (ITD) in the juxtamembrane region of the receptor ... -
FLT3-ITD mutations in acute myeloid leukaemia – molecular characteristics, distribution and numerical variation
(Journal article; Peer reviewed, 2021)Recurrent somatic internal tandem duplications (ITD) in the FMS-like tyrosine kinase 3 (FLT3) gene characterise approximately one third of patients with acute myeloid leukaemia (AML), and FLT3-ITD mutation status guides ... -
Fluctuating biomarkers in primary sclerosing cholangitis: A longitudinal comparison of alkaline phosphatase, liver stiffness, and ELF
(Journal article; Peer reviewed, 2021)Background & Aims Primary sclerosing cholangitis (PSC) is a progressive liver disease characterised by fluctuating liver biochemistries and highly variable disease progression. The Enhanced Liver Fibrosis (ELF®) test and ... -
Fluorochrome Selection for Imaging Intraoperative Ovarian Cancer Probes
(Journal article; Peer reviewed, 2022)The identification and removal of all gross and microscopic tumor to render the patient disease free represents a huge challenge in ovarian cancer treatment. The presence of residual disease is an independent negative ...