Blar i Department of Clinical Science på tittel

Viser treff 1929-1948 av 2340

    • A Research and Development (R&D) roadmap for influenza vaccines: Looking toward the future 

      Moore, Kristine A.; Ostrowsky, Julia T.; Kraigsley, Alison M.; Mehr, Angela J.; Bresee, Joseph S.; Friede, Martin H.; Gellin, Bruce G.; Golding, Josephine P.; Hart, Peter J.; Moen, Ann; Weller, Charlotte L.; Osterholm, Michael T.; Ampofo, William; Barclay, Wendy; Cavaleri, Marco; Cohen, Cheryl; Cowling, Benjamin; Cox, Rebecca Jane; Gust, Ian; Innis, Bruce; Kang, Gagandeep; Katz, Jacqueline M.; Krammer, Florian; Pitisuttithum, Punnee; Post, Diane; Rudenko, Larisa; Siqueira, Marilda M.; Weir, Jerry P. (Journal article; Peer reviewed, 2021)
      Improved influenza vaccines are urgently needed to reduce the burden of seasonal influenza and to ensure a rapid and effective public-health response to future influenza pandemics. The Influenza Vaccines Research and ...

    • Residential greenspace and lung function decline over 20 years in a prospective cohort: The ECRHS study 

      Markevych, Iana; Zhao, Tianyu; Fuertes, Elaine; Marcon, Alessandro; Dadvand, Payam; Vienneau, Danielle; Garcia Aymerich, Judith; Nowak, Dennis; de Hoogh, Kees; Jarvis, Deborah; Abramson, Michael J.; Accordini, Simone; Amaral, Andre FS; Bentouhami, Hayat; Bertelsen, Randi Jacobsen; Boudier, Anne; Bono, Roberto; Bowatte, Gayan; Casas, Lidia; Dharmage, Shyamali C; Forsberg, Bertil; Gislason, Thorarinn; Gnesi, Marco; Holm, Mathias; Jacquemin, Benedicte; Janson, Christer; Jogi, Rain; Johannessen, Ane; Keidel, Dirk; Leynaert, Benedicte; Maldonado Perez, José Antonio; Marchetti, Pierpaolo; Migliore, Enrica; Martínez-Moratalla, Jesús; Orru, Hans; Pin, Isabelle; Potts, James; Probst-Hensch, Nicole; Ranzi, Andrea; Sánchez-Ramos, José Luis; Siroux, Valerie; Soussan, David; Sunyer, Jordi; Urrutia Landa, Isabel; Villani, Simona; Heinrich, Joachim (Journal article; Peer reviewed, 2023)
      Background: The few studies that have examined associations between greenspace and lung function in adulthood have yielded conflicting results and none have examined whether the rate of lung function decline is ...

    • Residential surrounding greenspace and age at menopause: A 20-year European study (ECRHS) 

      Triebner, Kai; Markevych, Iana; Hustad, Simon Steinar; Benediktsdóttir, Bryndís; Forsberg, Bertil; Franklin, Karl A.; Gullón Blanco, José Antonio; Holm, Mathias; Jaquemin, Bénédicte; Jarvis, Debbie; Jõgi, Rain; Leynaert, Bénédicte; Lindberg, Eva; Martínez-Moratalla, Jesús; Muniozguren Agirre, Nerea; Pin, Isabelle; Sánchez-Ramos, José Luis; Heinrich, Joachim; Gomez Real, Francisco; Dadvand, Payam (Peer reviewed; Journal article, 2019-08-19)
      Background Menopause is associated with a number of adverse health effects and its timing has been reported to be influenced by several lifestyle factors. Whether greenspace exposure is associated with age at menopause has ...

    • Residual Corticosteroid Production in Autoimmune Addison Disease 

      Sævik, Åse Bjorvatn; Åkerman, Anna-Karin; Methlie, Paal; Quinkler, Marcus; Jørgensen, Anders Palmstrøm; Høybye, Charlotte; Debowska, Aleksandra; Nedrebø, Bjørn Gunnar; Dahle, Anne Lise; Carlsen, Siri; Tomkowicz, Aneta; Sollid, Stina Therese; Nermoen, Ingrid; Grønning, Kaja; Dahlqvist, Per; Grimnes, Guri; Skov, Jakob; Finnes, Trine Elisabeth; Valland, Susanna Fonneland; Wahlberg, Jeanette; Holte, Synnøve Emblem; Simunkova, Katerina; Kämpe, Olle; Husebye, Eystein Sverre; Bensing, Sophie; Øksnes, Marianne (Journal article; Peer reviewed, 2020)
      Design: Two-staged, cross-sectional clinical study in 17 centers (Norway, Sweden, and Germany). Residual glucocorticoid (GC) production was defined as quantifiable serum cortisol and 11-deoxycortisol and residual ...

    • Resistance to Chemotherapy in Breast Cancer: Potential role of p21B, p27 and the p53 apoptotic pathway 

      Chrisanthar, Ranjan (Doctoral thesis, 2009-03-13)

    • Resistance to the antiproliferative in vitro effect of PI3K-Akt-mTOR inhibition in primary human acute myeloid leukemia cells is associated with altered cell metabolism 

      Nepstad, Ina; Reikvam, Håkon; Brenner, Annette; Bruserud, Øystein; Hatfield, Kimberley Joanne (Peer reviewed; Journal article, 2018-01-27)
      Constitutive signaling through the phosphatidylinositol-3-kinase-Akt-mechanistic target of rapamycin (PI3K-Akt-mTOR) pathway is present in acute myeloid leukemia (AML) cells. However, AML is a heterogeneous disease, and ...

    • Respiratory Health in Cleaners in Northern Europe: Is Susceptibility Established in Early Life? 

      Svanes, Øistein; Skorge, Trude Duelien; Johannessen, Ane; Bertelsen, Randi Jacobsen; Bråtveit, Magne; Forsberg, Bertil; Gislason, Thorarin; Holm, Mathias; Janson, Christer; Jögi, Rain; Macsali, Ferenc; Norbäck, Dan; Omenaas, Ernst; Gomez Real, Francisco; Schlünssen, Vivi; Sigsgaard, Torben; Wieslander, Gunilla; Zock, Jan-Paul; Aasen, Tor Olav Brøvig; Dratva, Julia; Svanes, Cecilie (Journal article; Peer reviewed, 2015)
      Rationale There is some evidence that maternal smoking increases susceptibility to personal smoking’s detrimental effects. One might question whether early life disadvantage might influence susceptibility to occupational ...

    • Respiratory symptoms and cardiovascular causes of deaths: A population-based study with 45 years of follow-up 

      Stavem, Knut; Schirmer, Henrik; Gulsvik, Amund (Journal article; Peer reviewed, 2022)
      This study determined the association between respiratory symptoms and death from cardiovascular (CV) diseases during 45 years in a pooled sample of four cohorts of random samples of the Norwegian population with 95,704 ...

    • Respiratory symptoms and mortality in four general population cohorts over 45 years 

      Gulsvik, Amund; Bakke, Per; Brøgger, Jan; Nielsen, Rune; Stavem, Knut (Journal article; Peer reviewed, 2020)
      Objective: This study assessed the association between respiratory symptoms and mortality in four cohorts of the general population in Norway aged 15–75 years and in selected subgroups in the pooled sample. Methods: The ...

    • Respiratory symptoms as risk factors for mortality from all causes and from respiratory and cardiovascular disease and for incidence of lung cancer: a 30-year follow-up of a community study in Oslo 

      Frostad, Anne (Doctoral thesis, 2008-09-05)

    • Respiratory symptoms in adults are related to impaired quality of life, regardless of asthma and COPD: results from the European community respiratory health survey 

      Voll-Aanerud, Marianne; Eagan, Tomas Mikal; Plana, Estel; Omenaas, Ernst; Bakke, Per; Svanes, Cecilie; Siroux, Valerie; Pin, Isabelle; Antó, Josep M.; Leynaert, Benedicte (Peer reviewed; Journal article, 2010-09-27)
      Background Respiratory symptoms are common in the general population, and their presence is related to Health-related quality of life (HRQoL). The objective was to describe the association of respiratory symptoms with HRQoL ...

    • Respiratory viral infections in otherwise healthy humans with inherited IRF7 deficiency 

      Campbell, Tessa Mollie; Liu, Zhiyong; Zhang, Qian; Moncada-Velez, Marcela; Covill, Laura E.; Zhang, Peng; Darazam, Ilad Alavi; Bastard, Paul; Bizien, Lucy; Bucciol, Giorgia; Enoksson, Sara Lind; Jouanguy, Emmanuelle; Karabela, Şemsi Nur; Khan, Taushif; Kendir-Demirkol, Yasemin; Arias, Andres Augusto; Mansouri, Davood; Marits, Per; Marr, Nico; Migeotte, Isabelle; Moens, Leen; Ozcelik, Tayfun; Pellier, Isabelle; Sendel, Anton; Senoglu, Sevtap; Shahrooei, Mohammad; Edvard Smith, Smith; Vandernoot, Isabelle; Willekens, Karen; Yasar, Kadriye Kart; Bergman, Peter; Abel, Laurent; Cobat, Aurélie; Casanova, Jean-Laurent; Meyts, Isabelle; Bryceson, Yenan (Journal article; Peer reviewed, 2022)
      Autosomal recessive IRF7 deficiency was previously reported in three patients with single critical influenza or COVID-19 pneumonia episodes. The patients’ fibroblasts and plasmacytoid dendritic cells produced no detectable ...

    • The respiratory virome and exacerbations in patients with chronic obstructive pulmonary disease 

      van Rijn, Anneloes L.; van Boheemen, Sander; Sidorov, Igor; Carbo, Ellen C.; Pappas, Nikos; Mei, Hailiang; Feltkamp, Mariet; Aanerud, Marianne; Bakke, Per S.; Claas, Eric C.J.; Eagan, Tomas Mikal; Hiemstra, Pieter S.; Kroes, Aloys C.M.; de Vries, Jutte J.C. (Peer reviewed; Journal article, 2019-10-24)
      Introduction: Exacerbations are major contributors to morbidity and mortality in patients with chronic obstructive pulmonary disease (COPD), and respiratory bacterial and viral infections are an important trigger. However, ...

    • Responsiveness to influenza vaccination correlates with NKG2C-expression on NK cells 

      Riese, Peggy; Trittel, Stephanie; Pathirana, Rishi; Klawonn, Frank; Cox, Rebecca Jane; Guzmán, Carlos A. (Journal article; Peer reviewed, 2020-06-05)
      Influenza vaccination often results in a large percentage of low responders, especially in high-risk groups. As a first line of defense, natural killer (NK) cells play a crucial role in the fight against infections. However, ...

    • Resting heart rate, self-reported physical activity in middle age, and long-term risk of hip fracture. A NOREPOS cohort study of 367,386 men and women 

      Landgraff, Ida Kalstad; Meyer, Haakon Eduard; Ranhoff, Anette Hylen; Holvik, Kristin; Talsnes, Ove; Myrstad, Marius (Journal article; Peer reviewed, 2023)
      Enhanced knowledge regarding modifiable risk factors for hip fractures are warranted. We aimed to study the associations between two indicators of physical fitness (resting heart rate and level of physical activity) in ...

    • A restrictive policy for red blood cell transfusion in older hip fracture patients: experiences from a patient register 

      Martinsen, Mette; Valland, Haldor; Solheim, Ludvig Fjeld; Holvik, Kristin; Ranhoff, Anette Hylen (Peer reviewed; Journal article, 2016-02-09)
      Background: Allogeneic red blood cell transfusions (ABT) are common in older hip fracture patients. Recent research supports a restrictive transfusion policy. The aim was to study variation in hemoglobin (Hb) concentration, ...

    • Retained NK cell phenotype and functionality in non-alcoholic fatty liver disease 

      Stiglund, Natalie; Strand, Kristina; Cornillet, Martin; Stål, Per; Thorell, Anders; Zimmer, Christine L.; Näslund, Erik; Karlgren, Silja; Nilsson, Henrik; Mellgren, Gunnar; Fernø, Johan; Hagström, Hannes; Björkström, Niklas K. (Peer reviewed; Journal article, 2019-06-04)
      Non-alcoholic fatty liver disease (NAFLD), and the progressive stage non-alcoholic steatohepatitis (NASH), is the predominant cause of chronic liver disease globally. As part of the complex pathogenesis, natural killer ...

    • Retention Time and Fragmentation Predictors Increase Confidence in Identification of Common Variant Peptides 

      Skiadopoulou, Dafni; Vasicek, Jakub; Kuznetsova, Ksenia; Bouyssié, David; Käll, Lukas; Vaudel, Marc (Journal article; Peer reviewed, 2023)
      Precision medicine focuses on adapting care to the individual profile of patients, for example, accounting for their unique genetic makeup. Being able to account for the effect of genetic variation on the proteome holds ...

    • “Rethinking High-Grade Serous Carcinoma: Development of new tools for deep tissue profiling” 

      Anandan, Shamundeeswari (Doctoral thesis, 2021-09-03)
      Background: High-grade serous ovarian cancer (HGSOC) is the most frequently occurring and most fatal epithelial ovarian cancer (EOC) subtype. The reciprocal interplay of the different components encompassed within the ...

    • Rethinking High-Grade Serous Ovarian Carcinoma: Comprehensive Bioprofiling for Enhanced Identification of Surgical Phenotypes and Treatment Outcomes 

      Torkildsen, Cecilie Fredvik (Doctoral thesis, 2023-09-26)
      Bakgrunn: Til tross for betydelige fremskritt innenfor medisinsk og kirurgisk behandling er prognosen for høygradig serøs ovarialcarcinom (HGSOC) fremdeles dårlig. Kirurgi er sentralt for behandlingen, og fjerning av alle ...