Blar i Department of Clinical Science på tittel

Viser treff 2247-2266 av 2325

    • Unveiling sex bias and adverse neonatal outcomes in ultrasound estimation of gestational age: A population-based cohort study 

      Einum, Anders; Sørbye, Linn Marie; Nilsen, Roy Miodini; Ebbing, Cathrine; Morken, Nils-Halvdan (Journal article; Peer reviewed, 2024)
      Background Gestational age estimation by second-trimester ultrasound biometry introduces systematic errors due to sex differences in early foetal growth, consequently increasing the risk of adverse neonatal outcomes. ...

    • Update on primary sclerosing cholangitis 

      Karlsen, Tom Hemming; Boberg, Kirsten Muri (Peer reviewed; Journal article, 2013-09)
      Primary sclerosing cholangitis (PSC) remains one of the most challenging conditions of clinical hepatology. There has been a steady growth in research to overcome this fact and the present review aims at summarizing the ...

    • Updated total IgE reference intervals in Norwegian adults 

      Vinnes, Erik Wilhelm; Skarbø, Birthe Rochlenge Skarbø; Wentzel-Larsen, Tore; Sylte, Marit Sverresdotter; Apelseth, Torunn Oveland (Journal article; Peer reviewed, 2023)
      Background It is important and expected of laboratories to provide updated reference intervals to the clinician. As no recent publications report adult total IgE reference intervals on a Scandinavian population, the aim ...

    • The urban-rural gradient in asthma: A population-based study in Northern Europe 

      Timm, Signe; Frydenberg, Morten; Janson, Christer; Campbell, Brittany; Forsberg, Bertil; Gíslason, Þórarinn; Holm, Mathias; Jõgi, Rain; Omenaas, Ernst; Sigsgaard, Torben; Svanes, Cecilie; Schlünssen, Vivi (Peer reviewed; Journal article, 2015-12-30)
      The early life environment appears to have a persistent impact on asthma risk. We hypothesize that environmental factors related to rural life mediate lower asthma prevalence in rural populations, and aimed to investigate ...

    • Urinary excretion of homocysteine thiolactone and the risk of acute myocardial infarction in coronary artery disease patients: the WENBIT trial 

      Borowczyk, Kamila; Piechocka, Justyna; Głowacki, Rafał; Dhar, Indu; Midttun, Øivind; Tell, Grethe S.; Ueland, Per Magne; Nygård, Ottar; Jakubowski, Hieronim (Peer reviewed; Journal article, 2018)
      Objectives: No individual homocysteine (Hcy) metabolite has been studied as a risk marker for coronary artery disease (CAD). Our objective was to examine Hcy‐thiolactone, a chemically reactive metabolite generated by ...

    • Urinary Marker Profiles in Heart Failure with Reduced Versus Preserved Ejection Fraction 

      Streng, Koen W.; Hillege, Hans L.; ter Maaten, Jozine M.; van Veldhuisen, Dirk J.; Dickstein, Kenneth; Samani, Nilesh J.; Ng, Leong L.; Metra, Marco; Filippatos, Gerasimos S.; Ponikowski, Piotr; Zannad, Faiez; Anker, Stefan D.; van der Meer, Peter; Lang, Chim C.; Voors, Adriaan A.; Damman, Kevin (Journal article; Peer reviewed, 2023)
      Background Recent data suggest different causes of renal dysfunction between heart failure with reduced (HFrEF) versus preserved ejection fraction (HFpEF). We therefore studied a wide range of urinary markers reflecting ...

    • The use of 16S rRNA targeted next generation sequencing in diagnostics of polymicrobial invasive infections 

      Dyrhovden, Ruben (Doctoral thesis, 2023-08-21)
      16S rRNA dypsekvensering muliggjør, som vist i flere vitenskapelige arbeider, en mer fullstendig karakterisering av komplekse bakterielle mikrobiota enn det som kan oppnås ved tradisjonelle, dyrkningsbaserte, mikrobiologiske ...

    • Use of antihistamines before or during pregnancy and risk of early-onset pre-eclampsia in allergic women: a population-based cohort study 

      Sande, Anne Kvie; Torkildsen, Erik Andreas; Sande, Ragnar; Dalen, Ingvild; Danielsson, Kim Christian; Morken, Nils-Halvdan (Journal article; Peer reviewed, 2022)
      Objective: We have previously found that allergy is a risk factor for early-onset pre-eclampsia. The aim of this study was to assess the association between pregestational maternal use of antihistamines and early-onset ...

    • Use of conditional centiles of middle cerebral artery pulsatility index and cerebroplacental ratio in the prediction of adverse perinatal outcomes 

      Karlsen, Henriette Odland; Ebbing, Cathrine; Rasmussen, Svein; Kiserud, Torvid; Johnsen, Synnøve L. (Journal article, 2016-06)
      Introduction. Centiles of middle cerebral artery pulsatility index and cerebroplacental ratio are useful for predicting adverse perinatal outcomes. A ‘conditional centile’ is conditioned by a previous measurement reflecting ...

    • Use of inhaled ipratropium bromide to improve exercise-induced laryngeal obstruction cannot be recommended 

      Muralitharan, Praveen; Carlsen, Petter; Hilland, Magnus; Delestre-Levai, Irisz; Vollsæter, Maria; Hufthammer, Karl Ove; Engan, Mette; Røksund, Ola Drange; Halvorsen, Thomas; Clemm, Hege Synnøve Havstad (Journal article; Peer reviewed, 2023)
      Introduction: Exercise-induced laryngeal obstruction (EILO) is a common cause of exertional breathing problems in young adults. Current management generally consists of breathing advice, speech therapy, inspiratory muscle ...

    • Use of loop diuretics is associated with increased mortality in patients with suspected coronary artery disease, but without systolic heart failure or renal impairment: an observational study using propensity score matching 

      Schartum-Hansen, Hall; Løland, Kjetil Halvorsen; Svingen, Gard Frodahl Tveitevåg; Seifert, Reinhard; Pedersen, Eva Ringdal; Nordrehaug, Jan Erik; Bleie, Øyvind; Ebbing, Marta; Berge, Christ; Nilsen, Dennis W.T.; Nygård, Ottar (Peer reviewed; Journal article, 2015-06-01)
      Background Loop diuretics are widely used in patients with heart and renal failure, as well as to treat hypertension and peripheral edema. However, there are no randomized, controlled trials (RCT) evaluating their long ...

    • Use of microbiology tests in the era of increasing AMR rates- a multicentre hospital cohort study 

      Skodvin, Brita; Wathne, Jannicke Slettli; Lindemann, Paul Christoffer; Harthug, Stig; Nilsen, Roy Miodini; Charani, Esmita; Syre, Heidi; Kittang, Bård Reiakvam; Kleppe, Lars Kåre Selland; Smith, Ingrid (Peer reviewed; Journal article, 2019-02-04)
      Background: Effective use of microbiology test results may positively influence patient outcomes and limit the use of broad-spectrum antibiotics. However, studies indicate that their potential is not fully utilized. We ...

    • Use of Non-Steroidal Anti-Inflammatory Drugs among elderly patients in selected Norwegian Nursing Homes. 

      Beyene, Senay Abraha (Master thesis, 2021-12-19)

    • Use of probiotics to reduce infections and death and prevent colonization with extended-spectrum beta-lactamase (ESBL)- producing bacteria among newborn infants in Tanzania (ProRIDE Trial): study protocol for a randomized controlled clinical trial 

      Kuwelker, Kanika; Langeland, Nina; Löhr, Iren Høyland; Gidion, Joshua; Manyahi, Joel; Moyo, Sabrina John; Blomberg, Bjørn; Klingenberg, Claus (Journal article; Peer reviewed, 2021)
      Background Extended-spectrum beta-lactamase-producing Enterobacteriaceae (ESBL-E) has emerged as an urgent global health threat and is by the World Health Organization ranked as priority 1 among pathogens in need of new ...

    • Use of References in Responses from Scandinavian Drug Information Centres 

      Schjøtt, Jan; Böttiger, Ylva; Damkier, Per; Reppe, Linda Amundstuen; Kampmann, Jens Peter; Christensen, Hanne Rolighed; Spigset, Olav (Journal article, 2018)
      Background: The aim of this study was to compare use of references in responses from Scandinavian drug information centres (DICs). Methods: Six different fictitious drug-related queries were sent to each of seven Scandinavian ...

    • Using iPSC Models to Understand the Role of Estrogen in Neuron–Glia Interactions in Schizophrenia and Bipolar Disorder 

      de Assis, Denis; Szabo, Attila; Osete, Jordi Requena; Puppo, Francesca; O'Connell, Kevin S.; Akkouh, Ibrahim; Hughes, Timothy; Frei, Evgeniia; Andreassen, Ole Andreas; Djurovic, Srdjan (Journal article; Peer reviewed, 2021)
      Schizophrenia (SCZ) and bipolar disorder (BIP) are severe mental disorders with a considerable disease burden worldwide due to early age of onset, chronicity, and lack of efficient treatments or prevention strategies. ...

    • Using metabolic profiling and gene expression analyses to explore molecular effects of replacing saturated fat with polyunsaturated fat-a randomized controlled dietary intervention study 

      Ulven, Stine Marie; Christensen, Jacob J.; Nygård, Ottar; Svardal, Asbjørn M.; Leder, Lena; Ottestad, Inger; Lysne, Vegard; Laupsa-Borge, Johnny; Ueland, Per Magne; Midttun, Øivind; Meyer, Klaus; McCann, Adrian; Andersen, Lene Frost; Holven, Kirsten Bjørklund (Peer reviewed; Journal article, 2019-04-26)
      Background: Replacing dietary saturated fatty acids (SFAs) with polyunsaturated fatty acids (PUFA) reduces the plasma low-density lipoprotein (LDL) cholesterol and subsequently the risk of cardiovascular disease. However, ...

    • VACCELERATE Site Network: Real-time definition of clinical study capacity in Europe 

      Salmanton-García, Jon; Wipfler, Pauline; Valle-Simón, Paula; Merakou, Christina; Kopsidas, Ioannis; Bethe, Ullrich; Steinbach, Angela; Spivak, Orly; Součková, Lenka; Mendonça, Maria Amélia; Koniordou, Markela; Hellemans, Margot; Frías-Iniesta, Jesus; Davis, Ruth Joanna; Barta, Imre; Azzini, Anna Maria; Askling, Helena H.; Argyropoulos, Christos D.; Álvarez-Barco, Elena; Akova, Murat; Bonten, Marc M.J.; Cohen-Kandli, Miriam; Cox, Rebecca Jane; Flisiak, Robert; Husa, Petr; Jancoriene, Ligita; Koscalova, Alena; Launay, Odile; Lundgren, Jens; Mallon, Patrick; Marques, Laura; Nauclér, Pontus; Ochando, Jordi; Pana, Zoi-Dorothea; Tacconelli, Evelina; Tóth, Krisztina; Trelle, Sven; van Damme, Pierre; Zaoutis, Theoklis E.; Zeitlinger, Markus; Albus, Kerstin; Stewart, Fiona A.; Hofstraat, Sanne H.I.; Bruijning-Verhagen, Patricia; Cornely, Oliver A. (Journal article; Peer reviewed, 2023)
      Background: The inconsistent European vaccine trial landscape rendered the continent of limited interest for vaccine developers. The VACCELERATE consortium created a network of capable clinical trial sites throughout Europe. ...

    • VACCELERATE Volunteer Registry: A European study participant database to facilitate clinical trial enrolment 

      Salmanton-García, Jon; Stewart, Fiona A.; Heringer, Sarah; Koniordou, Markela; Álvarez-Barco, Elena; Argyropoulos, Christos D.; Themistocleous, Sophia C.; Valle-Simón, Paula; Spivak, Orly; Součková, Lenka; Merakou, Christina; Amélia Mendonça, Maria; Joanna Davis, Ruth; Maria Azzini, Anna; Askling, Helena H.; Vene, Sirkka; Van Damme, Pierre; Steinbach, Angela; Shiamakkides, George; Seidel, Danila; Olesen, Ole F.; Noula, Evgenia; Macken, Alan; Luís, Catarina; Leckler, Janina; Launay, Odile; Isitt, Catherine; Hellemans, Margot; Frías-Iniesta, Jesús; Di Marzo, Romina; Carcas, Antonio J.; Boustras, George; Borobia, Alberto M.; Barta, Imre; Albus, Kerstin; Akova, Murat; Ochando, Jordi; Cohen-Kandli, Miriam; Cox, Rebecca Jane; Husa, Petr; Jancoriene, Ligita; Mallon, Patrick; Marques, Laura; Mellinghoff, Sibylle C.; Nauclér, Pontus; Tacconelli, Evelina; Tóth, Krisztina; Zaoutis, Theoklis E.; Zeitlinger, Markus; Cornely, Oliver A.; Pana, Zoi-Dorothea (Journal article; Peer reviewed, 2022)
      Introduction: The coronavirus disease 2019 (COVID-19) pandemic has evidenced the key role of vaccine design, obtention, production and administration to successfully fight against infectious diseases and to provide efficient ...

    • Vaccination prevents severe COVID-19 outcome in patients with neutralizing type 1 interferon autoantibodies 

      Wolff, Anette Susanne Bøe; Hansen, Lena; Grytaas, Marianne Aardal; Oftedal, Bergithe Eikeland; Breivik, Lars Ertesvåg; Zhou, Fan; Hufthammer, Karl Ove; Sjøgren, Thea; Olofsson, Jan Stefan; Trieu, Mai Chi; Meager, Anthony; Jørgensen, Anders Palmstrøm; Lima, Kari; Mohn, Kristin Greve-Isdahl; Langeland, Nina; Cox Brokstad, Rebecca Jane; Husebye, Eystein Sverre (Journal article; Peer reviewed, 2023)
      A hallmark of patients with autoimmune polyendocrine syndrome type 1 (APS-1) is serological neutralizing autoantibodies against type 1 interferons (IFN-I). The presence of these antibodies has been associated with severe ...