Blar i Department of Clinical Science på tittel
Viser treff 291-310 av 2425
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Cardiac magnetic resonance imaging of myocardial mass and fibrosis in primary aldosteronism
(Peer reviewed; Journal article, 2018-03)Background Primary aldosteronism (PA) is associated with increased cardiovascular morbidity, presumably due to left ventricular (LV) hypertrophy and fibrosis. However, the degree of fibrosis has not been extensively studied. ... -
Cardiac morphology in neonates with fetal growth restriction
(Journal article; Peer reviewed, 2023)Objective: Assess effects of fetal growth restriction (FGR) on cardiac modelling in premature and term neonates. Study design: Prospective echocardiographic study of a cohort of FGR neonates (n = 21) and controls (n = 41) ... -
Cardiac organ damage in systemic hypertension: Impact of gender, etiology, and comorbidities
(Doctoral thesis, 2024-03-15)Bakgrunn: Ukontrollert systemisk hypertensjon fører til økt risiko for kardiovaskulær sykdom og død både ved essensiell og sekundær hypertensjon. Den økte risikoen skyldes i stor grad utvikling av strukturelle og funksjonelle ... -
Cardiac rehabilitation participation within 6 months of discharge in 37 136 myocardial infarction survivors: a nationwide registry study
(Journal article; Peer reviewed, 2023) -
Cardiac Resynchronization Therapy (CRT): Patient Selection and Guideline Adherence : An Analysis of CRT Practice in Europe Based on the European Society of Cardiology CRT Survey II with 11088 patients in 42 countries.
(Doctoral thesis, 2020-09-04)Background/Aims Cardiac Resynchronization Therapy (CRT) reduces morbidity and mortality in patients with heart failure and electrical dyssynchrony. Recommendations for which patients should receive a CRT device are outlined ... -
Cardiac Troponin Assays With Improved Analytical Quality: A Trade-Off Between Enhanced Diagnostic Performance and Reduced Long-Term Prognostic Value
(Journal article; Peer reviewed, 2020)Background Cardiac troponin (cTn) permits early rule‐out/rule‐in of patients admitted with possible non–ST‐segment–elevation myocardial infarction. In this study, we developed an admission and a 0/1 hour rule‐out/rule‐in ... -
Cardiac troponin measurement at the point of care: educational recommendations on analytical and clinical aspects by the IFCC Committee on Clinical Applications of Cardiac Bio-Markers (IFCC C-CB)
(Journal article; Peer reviewed, 2023)The International Federation of Clinical Chemistry and Laboarator Medicine (IFCC) Committee on Clinical Applications of Cardiac Bio-Markers (C-CB) has provided evidence-based educational resources to aid and improve the ... -
Cardiometabolic risk factors differ among adolescents with obesity in three European countries - a cross sectional study
(Peer reviewed; Journal article, 2018-03)Aim: We aimed to compare modifiable cardiometabolic risk factors among treatment‐seeking adolescents with obesity in Italy, Germany and Norway. Methods: This retrospective, registry‐based, cross‐sectional cohort study ... -
Cardioprotective Activity of Pharmacological Agents Affecting NO Production and Bioavailability in the Early Postnatal Period after Intrauterine Hypoxia in Rats
(Journal article; Peer reviewed, 2023)Intrauterine hypoxia in newborns leads to a multifaceted array of alterations that exert a detrimental impact on the cardiovascular system. The aim of this research was to assess the cardioprotective effects of modulators ... -
Cardiotoxicity of Doxorubicin. A Study of Methods and Protective Interventions in Rat Models
(Doctoral thesis, 2015-03-13)Introduction: The clinical use of anthracyclines, like doxorubicin, is a double-edged sword. On one side, anthracyclines play an undisputed key role in the treatment of many neoplastic diseases. On the other side; ... -
Cardiovascular organ damage in relation to hypertension status in patients with ankylosing spondylitis
(Journal article; Peer reviewed, 2023)Purpose Hypertension is a major cardiovascular (CV) risk factor in ankylosing spondylitis (AS) patients. Less is known about the prevalence of CV organ damage in relation to hypertension status in AS patients. Materials ... -
Cardiovascular risk markers in aortic valve stenosis : Insights in peak systolic left ventricular function, ejection dynamics and obesity
(Doctoral thesis, 2020-12-04)Background: Aortic valve stenosis (AS) is the most prevalent valvular heart disease requiring valvular intervention. With no pharmacological treatment available, optimal management requires detection of early left ventricular ... -
The carnitine-butyrobetaine-TMAO pathway after cardiac transplant: Impact on cardiac allograft vasculopathy and acute rejection
(Peer reviewed; Journal article, 2019)BACKGROUND: Alterations in the partly microbiota-dependent carnitine–γ-butyrobetaine (γBB)–trimethylamine N-oxide (TMAO) pathway have been linked to the progression of heart failure and atherosclerotic disease. We evaluated ... -
Carvedilol-enriched cold oxygenated blood cardioplegia improves left ventricular diastolic function after weaning from cardiopulmonary bypass
(Peer reviewed; Journal article, 2016-08)Objectives: To investigate whether adding carvedilol, a nonselective β- and selective α1-receptor blocking agent with antioxidant properties, to oxygenated blood cardioplegia improves myocardial function after weaning from ... -
Casein Kinase 2 (CK2): A Possible Therapeutic Target in Acute Myeloid Leukemia
(Journal article; Peer reviewed, 2023)The protein kinase CK2 (also known as casein kinase 2) is one of the main contributors to the human phosphoproteome. It is regarded as a possible therapeutic strategy in several malignant diseases, including acute myeloid ... -
Causal Analysis of World Health Organization's Surgical Safety Checklist Implementation Quality and Impact on Care Processes and Patient Outcomes: Secondary Analysis From a Large Stepped Wedge Cluster Randomized Controlled Trial in Norway
(Peer reviewed; Journal article, 2019)Objective: We hypothesize that high-quality implementation of the World Health Organization's Surgical Safety Checklist (SSC) will lead to improved care processes and subsequently reduction of peri- and postoperative ... -
CD24-targeted fluorescence imaging in patient-derived xenograft models of high-grade serous ovarian carcinoma
(Journal article; Peer reviewed, 2020)Background The survival rate of patients with advanced high-grade serous ovarian carcinoma (HGSOC) remains disappointing. Clinically translatable orthotopic cell line xenograft models and patient-derived xenografts (PDXs) ... -
CD24-targeted intraoperative fluorescence image-guided surgery leads to improved cytoreduction of ovarian cancer in a preclinical orthotopic surgical model
(Journal article; Peer reviewed, 2020)Background The completeness of resection is a key prognostic indicator in patients with ovarian cancer, and the application of tumour-targeted fluorescence image-guided surgery (FIGS) has led to improved detection of ... -
CD4 lymphocyte dynamics in Tanzanian pulmonary tuberculosis patients with and without hiv co-infection
(Peer reviewed; Journal article, 2012-03-21)Background: The interaction of HIV and tuberculosis (TB) on CD4 levels over time is complex and has been divergently reported. Methods: CD4 counts were assessed from time of diagnosis till the end of TB treatment in a ... -
CD64 as a potential biomarker in septic arthritis
(Peer reviewed; Journal article, 2013-06-19)Background Traditional inflammatory markers are generally unhelpful in discerning septic arthritis from inflammatory joint disease due to their lack of specificity. We wished to explore the discriminatory power of the novel ...