Blar i Department of Clinical Science på tittel
Viser treff 670-689 av 2426
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Effects of a multicomponent high intensity exercise program on physical function and health-related quality of life in older adults with or at risk of mobility disability after discharge from hospital: a randomised controlled trial
(Journal article; Peer reviewed, 2020)Background Many older people suffer from mobility limitations and reduced health-related quality of life (HRQOL) after discharge from hospital. A consensus regarding the most effective exercise-program to optimize physical ... -
Effects of anthocyanin supplementation on serum lipids, glucose, markers of inflammation and cognition in adults with increased risk of dementia - A pilot study
(Peer reviewed; Journal article, 2019-06-11)Background: Anthocyanins may protect against cardiovascular related cognitive decline and dementia. Objective: Open-label study to measure changes in serum lipids, glucose, glycosylated hemoglobin (HbA1c), and markers of ... -
Effects of applying universal fetal growth standards in a Scandinavian multi-ethnic population
(Peer reviewed; Journal article, 2018-02)Introduction: The question of whether universal growth charts can be used in multi‐ethnic settings is of general interest. The Intergrowth‐21st fetal growth and newborn size standards are suggested to represent optimal ... -
Effects of copy number variations on brain structure and risk for psychiatric illness: Large-scale studies from the ENIGMA working groups on CNVs
(Journal article; Peer reviewed, 2022)The Enhancing NeuroImaging Genetics through Meta-Analysis copy number variant (ENIGMA-CNV) and 22q11.2 Deletion Syndrome Working Groups (22q-ENIGMA WGs) were created to gain insight into the involvement of genetic factors ... -
Effects of cytarabine on activation of human T cells - cytarabine has concentration-dependent effects that are modulated both by valproic acid and all-trans retinoic acid
(Peer reviewed; Journal article, 2015-05-02)Background: Cytarabine is used in the treatment of acute myeloid leukemia (AML). Low-dose cytarabine can be combined with valproic acid and all-trans retinoic acid (ATRA) as AML-stabilizing treatment. We have investigated ... -
Effects of estradiol- and ethinylestradiol-based contraceptives on adrenal steroids: A randomized trial
(Journal article; Peer reviewed, 2022)Objectives: Ethinylestradiol (EE)-based combined oral contraceptives (COC) affect adrenal function by altering steroid and corticosteroid-binding globulin (CBG) synthesis that may contribute to adverse effects related to ... -
Effects of Fish Oil on 2,3,7,8-Tetrachlorodibenzo-para-dioxin and Polychlorinated Biphenyl 126 Toxicity on the Male Reproductive System of C57BL/6J Mice
(Master thesis, 2024-05-21)Abstract Background: Dioxins and dioxin-like polychlorinated biphenyls (dl-PCBs) are a group of contaminants associated with a wide range of adverse health effects. In 2018, the European Food Safety Authority (EFSA) ... -
Effects of interval training on inflammatory biomarkers in patients with ischemic heart failure
(Peer reviewed; Journal article, 2019)Objectives. Exercise training has been proposed to have anti-inflammatory effects. We examined whether aerobic interval training (AIT) can attenuate the inflammatory response in ischemic heart failure (HF) as measured by ... -
Effects of lifestyle intervention in persons at risk for type 2 diabetes mellitus - results from a randomised, controlled trial
(Peer reviewed; Journal article, 2011-11-25)Background: Lifestyle change is probably the most important single action to prevent type 2 diabetes mellitus. The purpose of this study was to assess the effects of a low-intensity individual lifestyle intervention by a ... -
Effects of n-3 fatty acid supplementations in elderly patients after myocardial infarction: A randomized controlled trial
(Journal article; Peer reviewed, 2021)Background: High intake of marine n-3 polyunsaturated fatty acids (PUFA) has been associated with reduced risk of cardiovascular events; however, this has not been confirmed in patients with a recent acute myocardial ... -
Effects of purified anthocyanins in people at risk for dementia: Study protocol for a phase II randomized controlled trial
(Journal article; Peer reviewed, 2020)Background: The number of people with dementia is increasing, with huge challenges for society and health-care systems. There are no disease-modifying therapies available. There is, therefore, an urgent need to identify ... -
Effects of replacing PSA with Stockholm3 for diagnosis of clinically significant prostate cancer in a healthcare system – the Stavanger experience
(Journal article; Peer reviewed, 2020)Objective To describe early experience of replacing PSA with Stockholm3 for detection of prostate cancer in primary care. Design and methods Longitudinal observations, comparing outcome measures before and after the ... -
Effects of sildenafil on symptoms and exercise capacity for heart failure with reduced ejection fraction and pulmonary hypertension (the SilHF study): a randomized placebo-controlled multicentre trial
(Journal article; Peer reviewed, 2022)Aims: Pulmonary hypertension (PHT) may complicate heart failure with reduced ejection fraction (HFrEF) and is associated with a substantial symptom burden and poor prognosis. Sildenafil, a phosphodiesterase-5 (PDE-5) ... -
The effects of smoking cessation intervention in patients with coronary heart disease : a randomised, controlled trial
(Doctoral thesis, 2007-02-09)Background: Smoking cessation is the most important action to reduce mortality after a coronary event. Largely, it has previously been unknown whether a smoking cessation program applicable in an ordinary clinical setting ... -
Effects of SNP variants in the 17β-HSD2 and 17β-HSD7 genes and 17β-HSD7 copy number on gene transcript and estradiol levels in breast cancer tissue
(Peer reviewed; Journal article, 2014-02-18)Breast cancers reveal elevated E2 levels compared to plasma and normal breast tissue. Previously, we reported intra-tumour E2 to be negatively correlated to transcription levels of 17β-HSD2 but positively correlated to ... -
Effects of the Autophagy-Inhibiting Agent Chloroquine on Acute Myeloid Leukemia Cells; Characterization of Patient Heterogeneity
(Journal article; Peer reviewed, 2021)Autophagy is a highly conserved cellular degradation process that prevents cell damage and promotes cell survival, and clinical efforts have exploited autophagy inhibition as a therapeutic strategy in cancer. Chloroquine ... -
Effekt av havregrynsgrøt på tykktarmens bakterieflora En eksplorativ studie av fekal beta-galaktosidase galaktosidaseog ureaseaktivitet i tykktarmen hos friske forsøkspersoner
(Master thesis, 2009-05-07)Irritabel tarm (IBS) er en kronisk lidelse som rammer ca. 15 prosent av befolkningen, og kjennetegnes ved magesmerter, oppblåsthet/gassplager og avføringsforstyrrelser. Det er mye som tyder på at bakteriefloraen til pasienter ... -
Efficacy and safety of 4 weeks' treatment with combined fluticasone furoate/vilanterol in a single inhaler given once daily in COPD: a placebo-controlled randomised trial
(Peer reviewed; Journal article, 2012-01-19)Background. Fluticasone furoate/vilanterol (FF/VI) is a novel once-daily (OD) inhaled corticosteroid/long-acting β2 agonist combination in development for chronic obstructive pulmonary disease (COPD) and asthma. Trial ... -
Efficacy and safety of baricitinib in hospitalized adults with severe or critical COVID‑19 (Bari‑SolidAct): a randomised, double‑blind, placebo‑controlled phase 3 trial
(Journal article; Peer reviewed, 2023)Background Baricitinib has shown efficacy in hospitalized patients with COVID-19, but no placebo-controlled trials have focused specifically on severe/critical COVID, including vaccinated participants. Methods Bari-SolidAct ... -
Efficacy of adrenal venous sampling is increased by point of care cortisol analysis
(Peer reviewed; Journal article, 2013)Primary aldosteronism (PA) is a common cause of secondary hypertension and is caused by unilateral or bilateral adrenal disease. Treatment options depend on whether the disease is lateralized or not, which is preferably ...