Blar i Department of Clinical Science på tittel
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Health-related quality of life, functional decline, and long-term mortality in older patients following hospitalisation due to COVID-19
(Journal article; Peer reviewed, 2021)Background Older people are particularly vulnerable to severe COVID-19. Little is known about long-term consequences of COVID-19 on health-related quality of life (HR-QoL) and functional status in older people, and the ... -
Healthy Nordic diet and associations with plasma concentrations of metabolites in the choline oxidation pathway: a cross-sectional study from Northern Sweden
(Journal article; Peer reviewed, 2023-05-17)Background: The choline oxidation pathway and metabolites involved have been linked to diseases including cardiovascular disease, type 2 diabetes and cancer. A healthy Nordic diet is a recently defined dietary pattern ... -
Heart Angiotensin-Converting Enzyme and Angiotensin-Converting Enzyme 2 Gene Expression Associated With Male Sex and Salt-Sensitive Hypertension in the Dahl Rat
(Journal article; Peer reviewed, 2021)Angiotensin-converting enzyme 2 (ACE 2) in the heart including its sex dependency in the hypertensive heart, has not been much studied compared to ACE. In the present study, we used the Dahl salt-sensitive rat exposed to ... -
Heart function by M-mode and tissue Doppler in the early neonatal period in neonates with fetal growth restriction
(Journal article; Peer reviewed, 2023)Background: Fetal growth restricted (FGR) neonates have increased risk of circulatory compromise due to failure of normal transition of circulation after birth. Aim: Echocardiographic assessment of heart function in FGR ... -
Heat shock factor 1 (Hsf1) cooperates with estrogen receptor α (erα) in the regulation of estrogen action in breast cancer cells
(Journal article; Peer reviewed, 2021)Heat shock factor 1 (HSF1), a key regulator of transcriptional responses to proteotoxic stress, was linked to estrogen (E2) signaling through estrogen receptor α (ERα). We found that an HSF1 deficiency may decrease ERα ... -
Heat shock proteins and chronic fatigue in primary Sjögren's syndrome
(Peer reviewed; Journal article, 2016)Fatigue occurs frequently in patients with cancer, neurological diseases and chronic inflammatory diseases, but the biological mechanisms that lead to and regulate fatigue are largely unknown. When the innate immune system ... -
Heat-shock protein 90α in plasma reflects severity of fatigue in patients with Crohn’s disease
(Peer reviewed; Journal article, 2020)Heat-shock proteins (HSPs) are evolutionarily conserved proteins with important cellular homeostasis functions during harmful conditions, including inflammation. Some HSPs are secreted extracellularly and act on distant ... -
Helminth exposure and its association with allergies and lung function in Northern European cohorts
(Doctoral thesis, 2022-09-19)Bakgrunn: De siste tiårene har forekomsten av astma og allergi økt over hele verden. I land hvor parasittinfeksjoner er endemiske, er forekomsten av astma og allergi lavere enn i land med lavere forekomst av parasitter. ... -
Helsepersonells erfaringar, tankar og haldningar til behovsmedisinering i sjukeheimar
(Master thesis, 2009-05-20)Behovslegemiddel er meint å bli gitt som respons på eit symptom eller medisinsk behov som oppstår hjå pasienten. Behovslegemiddel blir anten ført opp på den enkelte pasient sitt legemiddelkort, eller så kan ein nytte seg ... -
Hematopoiesis, Inflammation and Aging—The Biological Background and Clinical Impact of Anemia and Increased C‐Reactive Protein Levels on Elderly Individuals
(Journal article; Peer reviewed, 2022)Anemia and systemic signs of inflammation are common in elderly individuals and are associated with decreased survival. The common biological context for these two states is then the hallmarks of aging, i.e., genomic ... -
Hemophagocytic lymphohistiocytosis and miliary tuberculosis in a previously healthy individual: a case report
(Journal article; Peer reviewed, 2020)Background Hemophagocytic lymphohistiocytosis (HLH) is a rare heterogenous genetic or acquired hyperinflammatory syndrome associated with a high degree of morbidity and mortality. HLH has clinical manifestations related ... -
Hepatic Energy Metabolism Underlying Differential Lipidomic Responses to High-Carbohydrate and High-Fat Diets in Male Wistar Rats
(Journal article; Peer reviewed, 2021)Background Low-carbohydrate diets are suggested to exert metabolic benefits by reducing circulating triacylglycerol (TG) concentrations, possibly by enhancing mitochondrial activity. Objective We aimed to elucidate ... -
Hepcidin analysis in pneumonia: Comparison of immunoassay and LC-MS/MS
(Journal article; Peer reviewed, 2023)Background: The iron-regulatory hormone hepcidin is a promising biomarker to differentiate anaemia of inflammation from iron deficiency. Plasma hepcidin concentrations increase substantially during inflammation, and the ... -
Hepcidin and Ferritin Predict Microbial Etiology in Community-Acquired Pneumonia
(Journal article; Peer reviewed, 2021)Background Iron is crucial for survival and growth of microbes. Consequently, limiting iron availability is a human antimicrobial defense mechanism. We explored iron and iron-related proteins as potential biomarkers in ... -
Hepcidin predicts 5-year mortality after community-acquired pneumonia
(Journal article; Peer reviewed, 2022)Background Virtually all living organisms, including microbes and humans, depend on iron to survive and grow. During an infection, the plasma level of iron and several iron-related proteins change substantially. We ... -
HER2 expression patterns in paired primary and metastatic endometrial cancer lesions
(Peer reviewed; Journal article, 2017-11-23)Background: Despite successful implementation of drugs targeting the human epidermal growth factor receptor 2 (HER2) receptor in breast and gastric cancers, the potential of HER2 as a therapeutic target in other cancers ... -
Herbal plants used in traditional Chinese medicine as a source of compounds with potential medical utilities - identification, characterization and organization
(Master thesis, 2010-05-19)The history and knowledge of Chinese herbal medicine is over 3000 years old, and over 10 000 herbs are recorded and are in use for different conditions. This is an enormous amount of knowledge that can be used to find new ... -
Hereditary hypophosphatemia in Norway: A retrospective population-based study of genotypes, phenotypes, and treatment complications
(Peer reviewed; Journal article, 2016-02)Objective: Hereditary hypophosphatemias (HH) are rare monogenic conditions characterized by decreased renal tubular phosphate reabsorption. The aim of this study was to explore the prevalence, genotypes, phenotypic spectrum, ... -
Hereditary phosphate balance disorders in Norwegian children
(Doctoral thesis, 2016-05-03)Background: Hereditary hypophosphatemia (HH) is a group of diseases characterized by monogenic hypophosphatemia due to reduced tubular maximum reabsorption of phosphate per glomerular filtration rate (TmP/GFR). This group ... -
Herpesviral interactomics. Intraviral and virus-host protein-protein interaction network from different species of herpesviruses
(Doctoral thesis, 2008-02-01)