Blar i Department of Clinical Science på tittel
Viser treff 1005-1024 av 2522
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Haemagglutination inhibition and virus microneutralisation serology assays: use of harmonised protocols and biological standards in seasonal influenza serology testing and their impact on inter-laboratory variation and assay correlation: A FLUCOP collaborative study
(Journal article; Peer reviewed, 2023)Introduction: The haemagglutination inhibition assay (HAI) and the virus microneutralisation assay (MN) are long-established methods for quantifying antibodies against influenza viruses. Despite their widespread use, both ... -
Half of all hospitalised children treated with antibiotics for pneumonia did not fulfil radiological, microbiological or laboratory criteria
(Journal article; Peer reviewed, 2021)Aim Evaluating the management of paediatric pneumonia is important. We aimed to estimate the proportion of children receiving antibiotics for suspected community-acquired pneumonia (CAP) that were likely to have a bacterial ... -
Half of children with recurrent or chronic wet cough before three years of age were symptom-free by age seven
(Journal article; Peer reviewed, 2020)Aim We aimed to study the natural course of recurrent episodic and chronic wet cough in preschool children, the proportion and age of resolution, and risk factors for persistent symptoms. Methods Parents of children ... -
Handheld transabdominal ultrasound, after limited training, may confirm first trimester viable intrauterine pregnancy: a prospective cohort study
(Journal article; Peer reviewed, 2021)Objectives Handheld point-of-care abdominal ultrasound (POCUS) may be used by primary care physicians while vaginal ultrasound is limited to use in specialist care. We aimed to compare abdominal handheld ultrasound to ... -
Harmonization and qualification of an IFN-γ Enzyme-Linked ImmunoSpot assay (ELISPOT) to measure influenza-specific cell-mediated immunity within the FLUCOP consortium
(Journal article; Peer reviewed, 2022-09-08)Influenza continues to be the most important cause of viral respiratory disease, despite the availability of vaccines. Today’s evaluation of influenza vaccines mainly focuses on the quantitative and functional analyses of ... -
Harmonization and qualification of intracellular cytokine staining to measure influenza-specific CD4+ T cell immunity within the FLUCOP consortium
(Journal article; Peer reviewed, 2022-10-20)Despite the knowledge that cell-mediated immunity (CMI) contributes to the reduction of severe influenza infection, transmission, and disease outcome, the correlates of protection for cell-mediated immunity remain still ... -
Harnessing features of adaptive NK cells to generate iPSC-derived NK cells for enhanced immunotherapy
(Journal article; Peer reviewed, 2021)Select subsets of immune effector cells have the greatest propensity to mediate antitumor responses. However, procuring these subsets is challenging, and cell-based immunotherapy is hampered by limited effector-cell ... -
Hastegradsvurdering av akutt syke barn transportert i ambulanse
(Journal article; Peer reviewed, 2024)BAKGRUNN Helse Vest benytter en modifisert versjon av hastegradsverktøyet South African Triage Scale, SATS Norge (SATS-N), i alle akuttmottak og ambulansetjenester i regionen. Formålet med studien var å undersøke ... -
HbA1c versus oral glucose tolerance test as a method to diagnose diabetes mellitus in vascular surgery patients
(Peer reviewed; Journal article, 2013-05-25)Background: The diagnosis of diabetes mellitus (DM) is based on either fasting plasma glucose levels or an oral glucose tolerance test (OGTT). Recently, an HbA1c value of ≥48 mmol/mol (6.5%) has been included as an additional ... -
The HDACi panobinostat shows growth inhibition both in vitro and in a bioluminescent orthotopic surgical xenograft model of ovarian cancer
(Peer reviewed; Journal article, 2016-06-28)Background: In most epithelial ovarian carcinomas (EOC), epigenetic changes are evident, and overexpression of histone deacetylases (HDACs) represents an important manifestation. In this study, we wanted to evaluate the ... -
Head-to-head trial of pegunigalsidase alfa versus agalsidase beta in patients with Fabry disease and deteriorating renal function: Results from the 2-year randomised phase III BALANCE study
(Journal article; Peer reviewed, 2023)Background Pegunigalsidase alfa is a PEGylated α-galactosidase A enzyme replacement therapy. BALANCE (NCT02795676) assessed non-inferiority of pegunigalsidase alfa versus agalsidase beta in adults with Fabry disease with ... -
Headache in systemic lupus erythematosus and primary Sjogren's syndrome
(Doctoral thesis, 2016-11-09)Background Systemic lupus erythematosus (SLE) is a chronic inflammatory autoimmune disease which can affect multiple organs. The central nervous system (CNS) is frequently affected, and headache, especially migraine, is ... -
Health Literacy and Risk Factors for Coronary Artery Disease (From the CONCARD PCI Study)
(Journal article; Peer reviewed, 2022)In the setting of established coronary artery disease (CAD), lower health literacy is associated with poor outcomes. The aim of this study was to determine whether health literacy at the index admission was associated with ... -
Health professionals’ involvement of parents in decision-making in interprofessional practice at the hospital
(Peer reviewed; Journal article, 2020)Health professionals have the responsibility of involving parents in decision-making regarding children’s healthcare. This is to ensure that healthcare is customised to meet children’s and families’ needs and preferences. ... -
Health-related quality of life in patients with advanced melanoma treated with ipilimumab: prognostic implications and changes during treatment
(Journal article; Peer reviewed, 2022)Background: We have previously reported that the safety and efficacy of ipilimumab in real-world patients with metastatic melanoma were comparable to clinical trials. Few studies have explored health-related quality of ... -
Health-related quality of life, functional decline, and long-term mortality in older patients following hospitalisation due to COVID-19
(Journal article; Peer reviewed, 2021)Background Older people are particularly vulnerable to severe COVID-19. Little is known about long-term consequences of COVID-19 on health-related quality of life (HR-QoL) and functional status in older people, and the ... -
Healthcare professionals’ information need related to antiseizure medication use in breastfeeding patients with epilepsy. Retrospective analysis of enquiries to Norwegian medicines information and pharmacovigilance centers
(Journal article; Peer reviewed, 2023)Background: Safety information of antiseizure medication (ASM) during breastfeeding is scarce and conflicting. We aimed to identify characteristic traits of safety concerns among healthcare professionals by reviewing ... -
Healthy Nordic diet and associations with plasma concentrations of metabolites in the choline oxidation pathway: a cross-sectional study from Northern Sweden
(Journal article; Peer reviewed, 2023-05-17)Background: The choline oxidation pathway and metabolites involved have been linked to diseases including cardiovascular disease, type 2 diabetes and cancer. A healthy Nordic diet is a recently defined dietary pattern ... -
Heart Angiotensin-Converting Enzyme and Angiotensin-Converting Enzyme 2 Gene Expression Associated With Male Sex and Salt-Sensitive Hypertension in the Dahl Rat
(Journal article; Peer reviewed, 2021)Angiotensin-converting enzyme 2 (ACE 2) in the heart including its sex dependency in the hypertensive heart, has not been much studied compared to ACE. In the present study, we used the Dahl salt-sensitive rat exposed to ... -
Heart function by M-mode and tissue Doppler in the early neonatal period in neonates with fetal growth restriction
(Journal article; Peer reviewed, 2023)Background: Fetal growth restricted (FGR) neonates have increased risk of circulatory compromise due to failure of normal transition of circulation after birth. Aim: Echocardiographic assessment of heart function in FGR ...