Department of Clinical Science: Nye registreringer
Viser treff 321-340 av 2318
-
Persistent Fever and Positive PCR 90 Days Post-SARS-CoV-2 Infection in a Rituximab-Treated Patient: A Case of Late Antiviral Treatment
(Journal article; Peer reviewed, 2022)Background: Persistent fever after SARS-CoV-2 infection in rituximab-treated patients has been reported. Due to reduced sensitivity in conventional sampling methods and unspecific symptoms in these patients, distinguishing ... -
Family-based behavioral treatment of children with severe obesity : Effectiveness and perceived barriers
(Doctoral thesis, 2023-03-24)Bakgrunn: Få studier har prøvd ut familiebasert kognitiv atferdsterapi (FBT) innenfor den offentlige helsetjenesten. Mål: Sammenligne effekten av ... -
Aortic root dilatation in hypertensive patients with left ventricular hypertrophy–application of a new multivariate predictive model. The Life Study
(Journal article, 2022)Background: Available nomograms to predict aortic root (AoR) diameter for body surface area have limitations. The purpose of this study was to evaluate the use of a new multivariate predictive model to identify AoR dilatation ... -
Tidal volumes and pressures delivered by the NeoPuff T-piece resuscitator during resuscitation of term newborns
(Journal article; Peer reviewed, 2022)Aim: T-piece resuscitators are commonly used for respiratory support during newborn resuscitation. This study aimed to describe delivered pressures and tidal volumes when resuscitating term newborns immediately after birth, ... -
Patients with Bacterial Sepsis Are Heterogeneous with Regard to Their Systemic Lipidomic Profiles
(Journal article; Peer reviewed, 2023)Sepsis is defined as life-threatening organ dysfunction caused by a dysregulated host response to infection. In the present study, we investigated the systemic/serum lipidomic profile at the time of hospital admission for ... -
Functional analyses of BRCA1 variants of unknown significance found in hereditary breast or ovarian cancer families in Norway: A tool for improved diagnosis
(Doctoral thesis, 2023-03-21)Tumorsuppressorgenet BRCA1 speler mange viktige roller for å hindre tumorutvikling, og endringar i BRCA1-genet er ei av hovudårsakene til arveleg bryst- og eggstokk-kreft (HBOC). I artikkel I vart det laga ei oversikt over ... -
Paradoxical sinus deceleration during dobutamine stress echocardiography: case series and review of the literature
(Journal article; Peer reviewed, 2022)Background: Dobutamine stress echocardiography is an established diagnostic modality for assessing myocardial ischaemia in patients with known or suspected coronary artery disease. Dobutamine infusion causes dose-dependent ... -
The Effect of Protease-Activated Receptor-1 (PAR-1) Inhibition on Endothelial-Related Biomarkers in Patients with Coronary Artery Disease
(Journal article; Peer reviewed, 2022)Background: Vorapaxar has been shown to reduce cardiovascular mortality in postmyocardial infarction (MI) patients. Pharmacodynamic biomarker research related to protease-activated receptor-1 (PAR-1) inhibition with vorapaxar ... -
Prognostic value of baseline functional status measures and geriatric screening in vulnerable older patients with metastatic colorectal cancer receiving palliative chemotherapy – The randomized NORDIC9-study
(Journal article; Peer reviewed, 2023)Introduction Appropriate patient selection based on functional status is crucial when considering older adults for palliative chemotherapy. This pre-planned analysis of the randomized NORDIC9-study explored the prognostic ... -
Pathophysiological pathways related to high plasma growth differentiation factor 15 concentrations in patients with heart failure
(Journal article; Peer reviewed, 2022)Aims Elevated concentrations of growth differentiation factor 15 (GDF-15) in patients with heart failure (HF) have been consistently associated with worse clinical outcomes, but what disease mechanisms high GDF-15 ... -
A rapid antibody screening haemagglutination test for predicting immunity to SARS-CoV-2 variants of concern
(Journal article; Peer reviewed, 2022)Background: Evaluation of susceptibility to emerging SARS-CoV-2 variants of concern (VOC) requires rapid screening tests for neutralising antibodies which provide protection. Methods: Firstly, we developed a receptor-binding ... -
Analytical considerations in deriving 99th percentile upper reference limits for high-sensitivity cardiac troponin assays: Educational recommendations from the IFCC committee on clinical application of cardiac bio-markers
(Journal article; Peer reviewed, 2022)The International Federation of Clinical Chemistry Committee on Clinical Application of Cardiac Bio-Markers provides evidence-based educational documents to facilitate uniform interpretation and utilization of cardiac ... -
Inflammation and cognition in severe mental illness: patterns of covariation and subgroups
(Journal article; Peer reviewed, 2023)A potential relationship between dysregulation of immune/inflammatory pathways and cognitive impairment has been suggested in severe mental illnesses (SMI), such as schizophrenia (SZ) and bipolar (BD) spectrum disorders. ... -
Grading of Aortic Stenosis: Is it More Complicated in Women?
(Journal article; Peer reviewed, 2022)Aortic stenosis (AS) is the most common valvular heart disease and the main indication for valvular replacement in older women. Correct AS grading is mandatory for an adequate selection of patients for both surgical and ... -
Plasma Cholesterol- and Body Fat-Lowering Effects of Chicken Protein Hydrolysate and Oil in High-Fat Fed Male Wistar Rats
(Journal article; Peer reviewed, 2022)Rest raw materials provide a new source of bioactive dietary ingredients, and this study aimed to determine the health effects of diets with chicken protein hydrolysate (CPH) and chicken oil (CO) generated from deboned ... -
Epidemiology and etiology of primary ovarian insuffciency
(Doctoral thesis, 2023-03-02)Bakgrunn: Primær ovarialinsuffisiens (POI) er forårsaket av utilstrekkelig ovarieaktivitet og resulterer i for tidlig overgangsalder (alder <40 år). Diagnosen POI har livsendrende konsekvenser på grunn av infertilitet og ... -
A liposomal formulation of simvastatin and doxorubicin for improved cardioprotective and anti-cancer effect
(Journal article; Peer reviewed, 2022)Anthracyclines such as doxorubicin (Dox) are the preferred chemotherapeutics for several cancers. However, Dox-induced cardiotoxicity limits its therapeutic potential. Liposomal encapsulation of Dox has been used for ... -
A new software tool for computer assisted in vivo high-content analysis of transplanted fluorescent cells in intact zebrafish larvae
(Journal article; Peer reviewed, 2022)Acute myeloid leukemia and myelodysplastic syndromes are cancers of the bone marrow with poor prognosis in frail and older patients. To investigate cancer pathophysiology and therapies, confocal imaging of fluorescent ... -
Hyperglycemia in pregnancy. : Diagnostics, biomarkers, follow-up, and monitoring of glycemic control
(Doctoral thesis, 2023-02-24)Diabetes mellitus er blant de største globale folkehelseutfordringene i vår tid. Hyperglykemi affiserer ett av seks svangerskap og svangerskapsdiabetes (SVD) er den vanligste årsak. Gravide med hyperglykemi har økt risiko ... -
Changes in cardiopulmonary exercise capacity and limitations 3 to 12 months after COVID-19
(Journal article; Peer reviewed, 2023)Rationale: To describe cardiopulmonary function during exercise 12 months after hospital discharge for coronavirus disease 2019 (COVID-19), assess the change from 3 to 12 months, and compare the results with matched controls ...