Browsing Faculty of Medicine by Title
Now showing items 3378-3397 of 9009
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From direct attendance to telephone triage in an emergency primary healthcare service: An observational study
(Journal article; Peer reviewed, 2022)Objectives: To describe how an intervention to limit direct attendance in an emergency primary healthcare service affected the contacts to the clinic and the level of care given, and which factors were associated with a ... -
From genotype to phenotype: Through chromatin
(Peer reviewed; Journal article, 2019-01-23)Advances in sequencing technologies have enabled the exploration of the genetic basis for several clinical disorders by allowing identification of causal mutations in rare genetic diseases. Sequencing technology has also ... -
From hearing to seeing: medical dispatchers' experience with use of video streaming in medical emergency calls - a qualitative study
(Journal article; Peer reviewed, 2022)Objectives: Video streaming has recently been introduced as an additional tool for communication between medical dispatchers and caller. Research implies that video streaming may be a useful tool for the dispatchers, but ... -
From knowing our needs to enacting change: findings from community consultations with indigenous communities in Bangladesh
(Peer reviewed; Journal article, 2015-11-09)Introduction: Indigenous peoples are among the most marginalized peoples in the world due to issues relating to well-being, political representation, and economic production. The research consortium Goals and Governance ... -
From rejection to the Nobel Prize: Karikó and Weissman’s pioneering work on mRNA vaccines, and the need for diversity and inclusion in translational immunology
(Journal article; Peer reviewed, 2023)Katalin Karikó and Drew Weissman were given the 2023 Nobel Prize in Physiology or Medicine for their findings of nucleoside base modifications that lead to the development of effective mRNA vaccines against COVID-19. This ... -
FTO, Type 2 Diabetes, and Weight Gain Throughout Adult Life: A Meta-Analysis of 41,504 Subjects From the Scandinavian HUNT, MDC, and MPP Studies
(Journal article; Peer reviewed, 2011-05)OBJECTIVE—FTO is the most important polygene identified for obesity. We aimed to investigate whether a variant in FTO affects type 2 diabetes risk entirely through its effect on BMI and how FTO influences BMI across adult ... -
Fucosylated AGP glycopeptides as biomarkers of HNF1A-Maturity onset diabetes of the young
(Journal article; Peer reviewed, 2022)Aims: We previously demonstrated that antennary fucosylated N-glycans on plasma proteins are regulated by HNF1A and can identify cases of Maturity-Onset Diabetes of the Young caused by HNF1A variants (HNF1A-MODY). Based ... -
FuelBox Sunn Idrett- prosessevaluering av et dialogverktøy for ungdom om mat, kropp og trening
(Master thesis, 2022-05-13)Bakgrunn: Dialogverktøyet FuelBox Sunn Idrett er et potensielt tiltak for idrettsungdom for å igangsette samtaler og fremme refleksjon rundt vanskelige temaer som mat, kropp og trening. Spiseforstyrrelser er et alvorlig ... -
Fueling the flames of colon cancer – does CRP play a direct pro-inflammatory role?
(Journal article; Peer reviewed, 2023-03-17)Background: Systemic inflammation, diagnostically ascribed by measuring serum levels of the acute phase reactant C-reactive protein (CRP), has consistently been correlated with poor outcomes across cancer types. CRP exists ... -
Full breastfeeding protection against common enteric bacteria and viruses: Results from the MAL-ED cohort study
(Journal article; Peer reviewed, 2022)Background Breastfeeding is known to reduce the risk of enteropathogen infections, but protection from specific enteropathogens is not well characterized. Objective The aim was to estimate the association between full ... -
Fun, influence and competence-a mixed methods study of prerequisites for high school students' participation in physical education
(Peer reviewed; Journal article, 2017-03-10)Background: Many adolescents do not reach the recommended levels of physical activity (PA), and students attending vocational studies are less committed to take part in physical education (PE) than other students. The ... -
Function and regulation of phenylalanine and tyrosine hydroxylases from human and Caenorhabditis elegans. With focus in evolutionary aspects and development of new therapies
(Doctoral thesis, 2010-06-11)The family of the aromatic amino acid hydroxylases (AAAH) is well studied in mammals. It includes four members, i.e. phenylalanine hydroxylase (PAH), tyrosine hydroxylase (TH) and the tryptophan hydroxylases (TPH1 and 2). ... -
Function and regulation of Steroid Receptor Coactivator 2. Transcriptional regulation of cellular metabolism
(Doctoral thesis, 2015-12-18)Nuclear hormone receptors (NRs) associate with coregulators to enable complex programs of gene expression. The p160 steroid receptor coactivator 2 (SRC- 2/GRIP1) regulates metabolism and cellular processes in a tissue-specific ... -
A function of profilin in force generation during malaria parasite motility that is independent of actin binding
(Journal article; Peer reviewed, 2020)During transmission of malaria-causing parasites from mosquito to mammal, Plasmodium sporozoites migrate at high speed within the skin to access the bloodstream and infect the liver. This unusual gliding motility is based ... -
Functional analyses of BRCA1 variants of unknown significance found in hereditary breast or ovarian cancer families in Norway: A tool for improved diagnosis
(Doctoral thesis, 2023-03-21)Tumorsuppressorgenet BRCA1 speler mange viktige roller for å hindre tumorutvikling, og endringar i BRCA1-genet er ei av hovudårsakene til arveleg bryst- og eggstokk-kreft (HBOC). I artikkel I vart det laga ei oversikt over ... -
Functional Analyses of Rare Germline Missense BRCA1 Variants Located within and outside Protein Domains with Known Functions
(Journal article; Peer reviewed, 2023-01-19)The BRCA1 protein is implicated in numerous important cellular processes to prevent genomic instability and tumorigenesis, and pathogenic germline variants predispose carriers to hereditary breast and ovarian cancer (HBOC). ... -
Functional analysis of tilS homologues in Bacteria and Archaea
(Master thesis, 2005-09-09)Out of all of the microorganisms sequenced so far about one third of the genes have unknown function. Several studies have shown that information on evolutionary relationships between unknown genes can aid in the prediction ... -
Functional and animal studies of short-chain 3-hydroxyacyl-CoA dehydrogenase (SCHAD), a fatty acid beta-oxidation enzyme involved in congenital hyperinsulinism of infancy
(Doctoral thesis, 2021-02-16)Short-chain 3-hydroxyacyl-CoA dehydrogenase (SCHAD) is a mitochondrial enzyme involved in fatty acid β-oxidation and the regulation of β-cell insulin secretion. Its role in insulin secretion became apparent in 2001 when ... -
Functional and Binding H1N1pdm09-Specific Antibody Responses in Occasionally and Repeatedly Vaccinated Healthcare Workers: A Five-Year Study (2009-2014)
(Journal article; Peer reviewed, 2021)Background: In 2009, a novel influenza A/H1N1pdm09 emerged and caused a pandemic. This strain continued to circulate and was therefore included in the seasonal vaccines up to the 2016/2017-season. This provided a unique ... -
Functional and Prognostic Role of MicroRNAs in Cancer Associated Fibroblasts and Stroma in Oral Squamous Cell Carcinoma
(Doctoral thesis, 2023-11-23)Nyere studier har vist at forandringer i bindevevscellene som omgir kreftsvulsten er viktige for utviklingen av munnhulekreft. Kreft stroma kan regulere fenotypen av kreftcellene, og på den måten kan påvirke klinisk forløpet ...