Browsing Faculty of Medicine by Title
Now showing items 5408-5427 of 8877
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Metastatic tumor of the interventricular septum mimicking myocardial calcification: The role of multimodality imaging
(Journal article; Peer reviewed, 2021)Recently, there has been focus on how a round-shaped metastatic or dystrophic myocardial calcification, a rare type of myocardial pathology with different imaging appearances, can mimic a tumor in the basal interventricular ... -
Metformin exposure in first trimester of pregnancy and risk of all or specific congenital anomalies: exploratory case-control study
(Peer reviewed; Journal article, 2018)Objective: To investigate whether exposure to metformin during the first trimester of pregnancy, for diabetes or other indications, increases the risk of all or specific congenital anomalies. Design: Population based ... -
Metformin exposure, maternal PCOS status and fetal venous liver circulation: A randomized, placebo-controlled study
(Journal article; Peer reviewed, 2022-01-28)Background: Metformin is prescribed to women with polycystic ovary syndrome (PCOS) to prevent pregnancy complications. Children exposed to metformin vs. placebo in utero, have increased head circumference at birth and are ... -
Metformin inhibits hepatocellular glucose, lipid and cholesterol biosynthetic pathways by transcriptionally suppressing steroid receptor coactivator 2 (SRC-2)
(Peer reviewed; Journal article, 2015-11-09)The ability of the anti-diabetic drug metformin to inhibit anabolic processes including gluconeogenesis and lipogenesis is partly attributable to activation of the AMP-activated protein kinase (AMPK) pathway. The p160 ... -
Metformin Therapy Changes Gut Microbiota Alpha-Diversity in COVID-19 Patients with Type 2 Diabetes: The Role of SARS-CoV-2 Variants and Antibiotic Treatment
(Journal article; Peer reviewed, 2023)The gut microbiota play a crucial role in maintaining host health and have a significant impact on human health and disease. In this study, we investigated the alpha diversity of gut microbiota in COVID-19 patients and ... -
Metformin treatment response is dependent on glucose growth conditions and metabolic phenotype in colorectal cancer cells
(Journal article; Peer reviewed, 2021)Cancer cells exhibit altered metabolism, a phenomenon described a century ago by Otto Warburg. However, metabolic drug targeting is considered an underutilized and poorly understood area of cancer therapy. Metformin, a ... -
A method for dierentiating human induced pluripotent stem cells toward functional cardiomyocytes in 96‐well microplates
(Journal article; Peer reviewed, 2020)The capacity of pluripotent stem cells both for self-renewal and to differentiate into any cell type have made them a powerful tool for studying human disease. Protocols for efficient differentiation towards cardiomyocytes ... -
Method Paper – Distance and Travel Time to Casualty Clinics in Norway Based on Crowdsourced Postcode Coordinates: A Comparison with Other Methods
(Peer reviewed; Journal article, 2014-02-14)We describe a method that uses crowdsourced postcode coordinates and Google maps to estimate average distance and travel time for inhabitants of a municipality to a casualty clinic in Norway. The new method was compared ... -
Methodological considerations of clinical studies on low back pain
(Master thesis, 2001) -
Methodological issues in airway microbiome studies
(Doctoral thesis, 2020-12-04)Background Studies on the lung microbiome face unique methodological challenges tied to the low bacterial load of acquired samples and the increased susceptibility to bacterial DNA contamination. Contamination may be ... -
Methodologies for assessing telemedicine: a systematic review of reviews
(Peer reviewed; Journal article, 2012-01)Background and objectives: Previous reviews have expressed concerns about the quality of telemedicine studies. There is debate about shortcomings and appropriate methodologies. The aim of this review of systematic reviews ... -
Methods for providing an earlier warning of emerging drug trends
(Doctoral thesis, 2009-11-19)There is increasing international interest in the improved timely identification and reporting of new and emerging drug trends. Research directed at examining drug trends is particularly important in the contemporary context ... -
Meticillinresistente gule stafylokokker i sårsekret hos barn
(Journal article; Peer reviewed, 2022)BAKGRUNN Hud- og bløtvevsinfeksjoner er vanlig hos barn. Vi ønsket å undersøke forekomsten av meticillinresistens blant gule stafylokokker i sårsekret fra barn i Norge. MATERIALE OG METODE Vi gjennomførte en ... -
Metric based virtual simulation training for endovascular thrombectomy improves interventional neuroradiologists’ simulator performance
(Journal article; Peer reviewed, 2022)Objective Metric based virtual reality simulation training may enhance the capability of interventional neuroradiologists (INR) to perform endovascular thrombectomy. As pilot for a national simulation study we examined ... -
Metronidazole-sensitive organisms in children with severe acute malnutrition: an evaluation of the indication for empiric metronidazole treatment
(Peer reviewed; Journal article, 2020)Objectives: Children with severe acute malnutrition (SAM) are treated with empiric amoxicillin or penicillin and gentamicin because of the high risk of severe infections. Experts have suggested, based on available evidence, ... -
The MHC-II transactivator CIITA, a viral restriction factor inhibiting the replication of Human T-Cell Lymphotropic Virus Type 1
(Conference lecture, 2011-06-06) -
Mice depleted for Exchange Proteins Directly Activated by cAMP (Epac) exhibit irregular liver regeneration in response to partial hepatectomy
(Peer reviewed; Journal article, 2019-09-24)The exchange proteins directly activated by cAMP 1 and 2 (Epac1 and Epac2) are expressed in a cell specific manner in the liver, but their biological functions in this tissue are poorly understood. The current study was ... -
Microalbuminuria among Type 1 and Type 2 diabetic patients of African origin in Dar Es Salaam, Tanzania
(Peer reviewed; Journal article, 2007-01-15)Background: The prevalences and risk factors of microalbuminuria are not full described among black African diabetic patients. This study aimed at determining the prevalence of microalbuminuria among African diabetes ... -
Microarray-based gene expression profiling and DNA copy number variation analysis of temporal fossa arachnoid cysts
(Peer reviewed; Journal article, 2010-02-26)Background Intracranial arachnoid cysts (AC) are membranous sacs filled with CSF-like fluid that are commonly found in the temporal fossa. The majority of ACs are congenital. Typical symptoms are headache, dizziness, and ... -
Microbiological and bioinformatics analysis of primary Sjogren's syndrome patients with normal salivation
(Peer reviewed; Journal article, 2016-10-20)Background: Reduced salivation is considered a major clinical feature of most but not all cases of primary Sjögren’s syndrome (pSS). Reduced saliva flow may lead to changes in the salivary microbiota. These changes have ...