Browsing Faculty of Medicine by Title
Now showing items 5468-5487 of 8877
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Mitochondrial respiratory chain dysfunction—A hallmark pathology of idiopathic Parkinson’s disease?
(Journal article; Peer reviewed, 2022)Parkinson’s disease (PD) is the most common age-dependent neurodegenerative synucleinopathy. Loss of dopaminergic neurons of the substantia nigra pars compacta, together with region- and cell-specific aggregations of ... -
Mitokondriesykdom forårsaket av m.3243A>G-mutasjonen
(Journal article; Peer reviewed, 2022)Mitokondriesykdom er blant de vanligste metabolske sykdommene og er relevant for mange medisinske spesialiteter. Denne kliniske oversiktsartikkelen omtaler en av de vanligste mutasjonene bak mitokondriesykdom: m.3243A>G. ... -
Mitral annular dynamics are influenced by left ventricular load and contractility in an acute animal model
(Journal article; Peer reviewed, 2023)The purpose of this study was to investigate the effects of loading conditions and left ventricular (LV) contractility on mitral annular dynamics. In 10 anesthetized pigs, eight piezoelectric transducers were implanted ... -
"Mitt valg, mitt liv, mine tanker". En kvalitativ studie om erfaringer hos unge kvinner under 25 år med påvist genfeil i BRCA: Ventetiden før oppstart i kontrollopplegg.
(Master thesis, 2019)I Norge får kvinner med påvist genfeil i BRCA tilbud om mammografi og MR-undersøkelser fra fylte 25 år. Hensikten med denne kvalitative studien har vært å få innsikt i unge kvinners erfaringer og opplevelser i ventetiden ... -
Mixed Effect Modeling of Dose and Linear Energy Transfer Correlations With Brain Image Changes After Intensity Modulated Proton Therapy for Skull Base Head and Neck Cancer
(Journal article; Peer reviewed, 2021)Purpose Intensity modulated proton therapy (IMPT) could yield high linear energy transfer (LET) in critical structures and increased biological effect. For head and neck cancers at the skull base this could potentially ... -
The MOBID-2 pain scale: Reliability and responsiveness to pain in patients with dementia
(Peer reviewed; Journal article, 2014-05-05)Background: Mobilization-Observation-Behavior-Intensity-Dementia-2 (MOBID-2) pain scale is a staff-administered pain tool for patients with dementia. This study explores MOBID-2’s test–retest reliability, measurement error ... -
Mobility restrictions were associated with reductions in COVID-19 incidence early in the pandemic: evidence from a real-time evaluation in 34 countries
(Journal article; Peer reviewed, 2021)Most countries have implemented restrictions on mobility to prevent the spread of Coronavirus disease-19 (COVID-19), entailing considerable societal costs but, at least initially, based on limited evidence of effectiveness. ... -
Model variations in predicting incidence of Plasmodium falciparum malaria using 1998-2007 morbidity and meteorological data from south Ethiopia
(Peer reviewed; Journal article, 2010-06-16)Background: Malaria transmission is complex and is believed to be associated with local climate changes. However, simple attempts to extrapolate malaria incidence rates from averaged regional meteorological conditions have ... -
Modeling assortative mating and genetic similarities between partners, siblings, and in-laws
(Journal article; Peer reviewed, 2022)Assortative mating on heritable traits can have implications for the genetic resemblance between siblings and in-laws in succeeding generations. We studied polygenic scores and phenotypic data from pairs of partners ... -
Modeling psychiatric disorders: From genomic findings to cellular phenotypes
(Peer reviewed; Journal article, 2016)Major programs in psychiatric genetics have identified >150 risk loci for psychiatric disorders. These loci converge on a small number of functional pathways, which span conventional diagnostic criteria, suggesting a partly ... -
Modelling cellular signal communication mediated by phosphorylation dependent interaction with 14-3-3 proteins
(Peer reviewed; Journal article, 2014-01-03)The 14-3-3 proteins are important effectors of Ser/Thr phosphorylation in eukaryotic cells. Using mathematical modelling we investigated the roles of these proteins as effectors in signalling pathways that involve ... -
Modelling hospital operations: Insight from using data from paper registries in the obstetrics ward at a hospital in Addis Ababa, Ethiopia
(Journal article; Peer reviewed, 2019)In the Ethiopian health system, operations management techniques have been underutilised. Although previous research has outlined limitations of paper-based patient records, few studies have examined their potential utility ... -
Modern contraceptive use among postpartum women living with HIV attending mother baby care points in Kabarole District, Uganda
(Journal article; Peer reviewed, 2020-04-22)Background: Preventing unintended pregnancies among women living with HIV is important for improving maternal and child health outcomes. Despite multiple contacts between postpartum women and healthcare providers at health ... -
Modes of e-Health delivery in secondary prevention programmes for patients with coronary artery disease: A systematic review
(Peer reviewed; Journal article, 2019-06-10)Background: Electronic health (e-Health) interventions are emerging as an effective alternative model for improving secondary prevention of coronary artery disease (CAD). The aim of this study was to describe the effectiveness ... -
Modic changes-Their associations with low back pain and activity limitation: A systematic literature review and meta-analysis
(Peer reviewed; Journal article, 2018-08-01)Background: Previous systematic reviews have reported positive associations between Modic changes (MCs) and low back pain (LBP), but due to their narrow scope and new primary studies, there is a need for a comprehensive ... -
Modifiable and non-modifiable risk factors for obstetric anal sphincter injury in a Norwegian Region: a case–control study
(Journal article; Peer reviewed, 2022-04-01)Background: Obstetric anal sphincter injury (OASI) is a common and severe complication of vaginal delivery and may have short- and long-term consequences, including anal incontinence, sexual dysfunction and reduced quality ... -
Modifiable and non-modifiable risk factors in hip fracture mortality in Norway, 2014 to 2018 - a linked multiregistry study
(Journal article; Peer reviewed, 2022)Aims This study aimed to identify risk factors (patient, healthcare system, and socioeconomic) for mortality after hip fractures and estimate their relative importance. Further, we aimed to elucidate mortality and survival ... -
Modifiable cardiovascular disease risk factors among adults in southern Ethiopia: a community-based cross-sectional study
(Journal article; Peer reviewed, 2022)Objective To assess the prevalence, magnitude and factors associated with the number of major modifiable cardiovascular disease (CVD) risk factors. Design Community-based cross-sectional study. Setting General ... -
Modulating the unfolded protein response with ONC201 to impact on radiation response in prostate cancer cells
(Journal article; Peer reviewed, 2021)Prostate cancer (PCa) is the most common non-cutaneous cancer in men and a notable cause of cancer mortality when it metastasises. The unfolded protein response (UPR) can be cytoprotective but when acutely activated can ... -
Modulating Wnt signaling in human induced pluripotent stem cell-derived S7 cells
(Peer reviewed; Journal article, 2019)Current published protocols for targeted differentiation of human stem cells toward pancreatic β-cells fail to deliver sufficiently mature cells with functional properties comparable to human islet β-cells. We aimed to ...