Blar i Faculty of Medicine på tittel

Viser treff 8035-8054 av 9009

    • Structure to function analysis with antigenic characterization of a hypothetical protein, HPAG1_0576 from Helicobacter pylori HPAG1 

      Ashrafi, Hanan; Siraji, Muntequa Ishtiaq; Showva, Nazmir Nur; Hossain, Md. Mozamme; Hossan, Tareq; Hasan, Md. Ashraful; Shohael, Abdullah Mohammad; Shawan, Mohammad Mahfuz Ali Khan (Peer reviewed; Journal article, 2019-07-31)
      Helicobacter pylori, a unique gastric pathogen causing chronic inflammation in the gastric mucosa with a possibility to develop gastric cancer has one-third of its proteins still uncharacterized. In this study, a hypothetical ...

    • Structure-based design of pantothenate kinase inhibitors as lead structures for new antibiotics 

      Lee, Ying Ho Leon (Master thesis, 2020-06-23)

    • Structure-based Druggability Predictions of RNA Binding Sites and Design of RNA Ligands 

      Rekand, Illimar Hugo (Doctoral thesis, 2022-09-15)
      Den post-antibotiske æraen truer og for å møte denne krisen trengs det tilgang til nye klasser av antibiotika. Ribvoswitcher er cis-genregulerende foldete strukturer av ikke-kodende RNA, som handler gjennom konformasjonsendringer ...

    • Structured and Systematic Team and Procedure Training in Severe Trauma: Going from ‘Zero to Hero’ for a Time-Critical, Low-Volume Emergency Procedure Over Three Time Periods 

      Meshkinfamfard, Maryam; Narvestad, Jon; Larsen, Johannes Wiik; Kanani, Arezo; Vennesland, Jørgen Bendik; Reite, Andreas; Vetrhus, Morten; Thorsen, Kenneth; Søreide, Kjetil (Journal article; Peer reviewed, 2021)
      Background Resuscitative emergency thoracotomy is a potential life-saving procedure but is rarely performed outside of busy trauma centers. Yet the intervention cannot be deferred nor centralized for critically injured ...

    • STUB1 mutations in autosomal recessive ataxias - evidence for mutation-specific clinical heterogeneity 

      Heimdal, Ketil; Sanchez-Guixé, Monica; Aukrust, Ingvild; Bollerslev, Jens; Bruland, Ove; Jablonski, Greg Eigner; Erichsen, Anne Kjersti; Gude, Einar; Koht, Jeanette A.; Erdal, Sigrid; Fiskerstrand, Torunn; Haukanes, Bjørn Ivar; Boman, Helge; Bjørkhaug, Lise; Tallaksen, Chantal M. E.; Knappskog, Per; Johansson, Stefan (Peer reviewed; Journal article, 2014-09-26)
      Background: A subset of hereditary cerebellar ataxias is inherited as autosomal recessive traits (ARCAs). Classification of recessive ataxias due to phenotypic differences in the cerebellum and cerebellar structures is ...

    • Studier av G-protein koblende reseptorer ved bruk av Fluorescens - teknikker 

      Jørgensen, Wenche (Master thesis, 2009-05-28)
      Masteroppgaven tar for seg betydningen av den N-terminale halen på 5-HT2C og 5-HT2C-reseptorene, to forskjellige G-proteinkoblede reseptorer. Et spørsmål var om de har endogene signalpeptid, som prediktert i prediksjonsdatabasen ...

    • Studies of gene expression in the Parkinson’s disease brain 

      Dick, Fiona (Doctoral thesis, 2021-10-01)
      Parkinson’s disease (PD) is the second most prevalent neurodegenerative disorder, affecting ~1.8% of the population above 65 years. A combination of genetic and environmental factors contributes to the risk of PD, but the ...

    • Studies of α11β1 integrin in the mouse and human periodontal ligament 

      Barczyk, Malgorzata M. (Doctoral thesis, 2009-06-12)

    • Studies on homocysteine-lowering B-vitamin therapy in patients with coronary artery diseas : sub-studies from the Western Norway B-vitamin intervention trial (WENBIT) 

      Bleie, Øyvind (Doctoral thesis, 2008-06-06)
      Background: A high plasma level of total homocysteine (tHcy) is a risk factor for cardiovascular disease, and is related to important components of atherosclerosis such as inflammation and endothelial dysfunction. Objectives: ...

    • Studies on sequencing analyses of genetic and epigenetics features in melanoma and breast cancer 

      Poduval, Deepak B (Doctoral thesis, 2020-12-15)
      The dissertation includes 3 projects and in each work we applied different approaches to sequencing and bioinformatics analyses to gain a better understanding of the molecular characteristics of breast cancer and melanoma. ...

    • Studies on the Molecular Mechanisms of the Bystander Effect in HSV-TK mediated Suicide Gene Therapy for Glioblastoma Treatment 

      Jeyendran, Sayintha (Master thesis, 2020-08-07)

    • Studies on viral gene transfer and angiogenesis inhibition in experimental glioma models 

      Huszthy, Peter Csaba (Doctoral thesis, 2006-11-03)

    • Study and correction of defects in of tyrosine hydroxylase, the rate-limiting enzyme in the synthesis of dopamine 

      Tran, Maria Phuong Anh (Master thesis, 2019-06-18)

    • Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function 

      Davies, Gail; Lam, Max; Harris, Sarah E.; Trampush, Joey W.; Luciano, Michelle; Hill, W. David; Hagenaars, Saskia P.; Ritchie, Stuart J.; Marioni, Riccardo E.; Fawns-Ritchie, Chloe; Liewald, David C.M.; Okely, Judith A.; Ahola-Olli, Ari V.; Barnes, Catriona L.K.; Bertram, Lars; Bis, Joshua C.; Burdick, Katherine E.; Christoforou, Andrea; Derosse, Pamela; Djurovic, Srdjan; Espeseth, Thomas; Giakoumaki, Stella; Giddaluru, Sudheer; Gustavson, Daniel E.; Hayward, Caroline; Hofer, Edith; Ikram, M. Arfan; Karlsson, Robert; Knowles, Emma; Lahti, Jari; Leber, Markus; Li, Shuo; Mather, Karen A.; Melle, Ingrid; Morris, Derek; Oldmeadow, Christopher; Palviainen, Teemu; Payton, Antony; Pazoki, Raha; Petrovic, Katja; Reynolds, Chandra A.; Sargurupremraj, Muralidharan; Scholz, Markus; Smith, Jennifer A.; Smith, Albert V.; Terzikhan, Natalie; Thalamuthu, Anbupalam; Trompet, Stella; van der Lee, Sven J.; Ware, Erin B.; Windham, B. Gwen; Wright, Margaret J.; Yang, Jingyun; Yu, Jin; Ames, David; Amin, Najaf; Amouyel, Philippe; Andreassen, Ole Andreas; Armstrong, Nicola J.; Assareh, Amelia A; Attia, John R.; Attix, Deborah; Avramopoulos, Dimitrios; Bennett, David A.; Böhmer, Anne C.; Boyle, Patricia A.; Brodaty, Henry; Campbell, Harry; Cannon, Tyrone D.; Cirulli, Elizabeth T.; Congdon, Eliza; Conley, Emily Drabant; Corley, Janie; Cox, Simon R.; Dale, Anders; Dehghan, Abbas; Dick, Danielle; Dickinson, Dwight; Eriksson, Johan G.; Evangelou, Evangelos; Faul, Jessica D.; Ford, Ian; Freimer, Nelson A.; Gao, He; Giegling, Ina; Gillespie, Nathan A.; Gordon, Scott D.; Gottesman, Rebecca F.; Griswold, Michael E.; Gudnason, Vilmundur; Harris, Tamara B.; Hartmann, Annette M.; Hatzimanolis, Alex; Heiss, Gerardo; Holliday, Elizabeth G.; Joshi, Peter K.; Kähönen, Mika; Kardia, Sharon L.R.; Karlsson, Ida; Kleineidam, Luca; Knopman, David S.; Kochan, Nicole A.; Konte, Bettina; Kwok, John B.; Le Hellard, Stephanie; Lee, Teresa; Lehtimäki, Terho; Li, Shu-Chen; Liu, Tian; Koini, Marisa; London, Edythe; Longstreth, Will T.; Lopez, Oscar L.; Loukola, Anu; Luck, Tobias; Lundervold, Astri; Lundquist, Anders; Lyytikäinen, Leo-Pekka; Martin, Nicholas G.; Montgomery, Grant W.; Murray, Alison D.; Need, Anna C.; Noordam, Raymond; Nyberg, Lars; Ollier, William; Papenberg, Göran; Pattie, Alison; Polasek, Ozren; Poldrack, Russell A.; Psaty, Bruce M.; Reppermund, Simone; Riedel-Heller, Steffi G.; Rose, Richard J.; Rotter, Jerome I.; Roussos, Panos; Rovio, Suvi P.; Saba, Yasaman; Sabb, Fred W.; Sachdev, Perminder S.; Satizabal, Claudia L.; Schmid, Matthias; Scott, Rodney J.; Scult, Matthew A.; Simino, Jeannette; Slagboom, P. Eline; Smyrnis, Nikolaos; Soumaré, Aïcha; Stefanis, Nikos C.; Stott, David J.; Straub, Richard E.; Sundet, Kjetil Søren; Taylor, Adele M.; Taylor, Kent D.; Tzoulaki, Ioanna; Tzourio, Christophe; Uitterlinden, André; Vitart, Veronique; Voineskos, Aristotle N.; Kaprio, Jaakko; Wagner, Michael; Wagner, Holger; Weinhold, Leonie; Wen, K. Hoyan; Widén, Elisabeth; Yang, Qiong; Zhao, Wei; Adams, Hieab H.H.; Arking, Dan E.; Bilder, Robert M.; Bitsios, Panos; Boerwinkle, Eric; Chiba-Falek, Ornit; Corvin, Aiden; De Jager, Philip L.; Debette, Stéphanie; Donohoe, Gary; Elliott, Paul; Fitzpatrick, Annette L.; Gill, Michael; Glahn, David C.; Hägg, Sara; Hansell, Narelle K.; Hariri, Ahmad; Ikram, M. Kamran; Jukema, J. Wouter; Vuoksimaa, Eero; Keller, Matthew C.; Kremen, William S.; Launer, Lenore; Lindenberger, Ulman; Palotie, Aarno; Pedersen, Nancy L.; Pendleton, Neil; Porteous, David J.; Räikkönen, Katri; Raitakari, Olli T.; Ramirez, Alfredo; Reinvang, Ivar; Rudan, Igor; Rujescu, Dan; Schmidt, Reinhold; Schmidt, Helena; Schofield, Peter W.; Schofield, Peter R.; Starr, John M.; Steen, Vidar Martin; Trollor, Julian N.; Turner, Steven T.; Van Duijn, Cornelia M.; Villringer, Arno; Weinberger, Daniel R.; Weir, David R.; Wilson, James F.; Malhotra, Anil; McIntosh, Andrew M.; Gale, Catharine R.; Seshadri, Sudha; Mosley, Thomas H.; Bressler, Jan; Lencz, Todd; Deary, Ian J. (Peer reviewed; Journal article, 2018)
      General cognitive function is a prominent and relatively stable human trait that is associated with many important life outcomes. We combine cognitive and genetic data from the CHARGE and COGENT consortia, and UK Biobank ...

    • A study of recurrent unipolar major depression and executive functions 

      Stordal, Kirsten Irene (Doctoral thesis, 2006-11-24)
      Background: Unipolar major depression is a prevalent disorder and is in the World Health Organisation’s (WHO) top five on their global burden of disease-list. For more than three decades, assessment of neurocognitive ...

    • Study of the role of skin lymphatics in electrolyte and blood pressure regulation 

      Reikvam, Tore (Doctoral thesis, 2020-02-21)
      Cardiovascular diseases are the major cause of death worldwide and represent a dramatic socio-economic challenge. Hypertension accounts for 18% of cardiovascular disease deaths in the Western countries, and is a major risk ...

    • A study of TNF pathway activation in schizophrenia and bipolar disorder in plasma and brain tissue 

      Hoseth, Eva Zsuzsanna; Ueland, Thor; Dieset, Ingrid; Birnbaum, Rebecca; Shin, Joo Heon; Kleinman, Joel Edward; Hyde, Thomas Michael; Mørch, Ragni Helene; Hope, Sigrun; Lekva, Tove; Abraityte, Judita Aurelija; Michelsen, Annika; Melle, Ingrid; Westlye, Lars Tjelta; Ueland, Torill; Djurovic, Srdjan; Aukrust, Pål; Weinberger, Daniel R.; Andreassen, Ole Andreas (Peer reviewed; Journal article, 2017-07)
      Objective: A proinflammatory imbalance in the tumor necrosis factor (TNF) system may contribute to the pathogenesis of schizophrenia (SCZ) and bipolar disorders (BDs) and related comorbidities. We investigated the relative ...

    • A study on effects of safety checklists emphasizing quality of complication data 

      Storesund, Anette (Doctoral thesis, 2020-01-16)
      Introduction: Despite increased focus on patient safety, complication rates in hospitals have remained unchanged with reports ranging between one out of twenty patients and one out of four patients, often related to surgery. ...

    • A study on features and markers of cellular metabolic rewiring 

      Tusubira, Deusdedit (Doctoral thesis, 2019-02-15)
      Mammalian cells regulate energy metabolism through molecular responses linked to the microenvironment and nutrient supply. Context dependent abnormalities of energy metabolism are important in disorders such as cancer, ...

    • A study on metabolic rewiring in cancer cell plasticity 

      Dyrstad, Sissel Elisabeth (Doctoral thesis, 2020-08-21)
      Adaptation of cellular energetics is an important feature of tumorigenesis as a vast supply of nutrients is needed to accommodate increased growth. Essential energy pathways includes glucose, fatty acid and amino acid ...