Blar i Faculty of Medicine på tittel

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    • Reliable classification of children’s fractures according to the comprehensive classification of long bone fractures by Müller 

      Meling, Terje; Harboe, Knut; Enoksen, Cathrine H.; Aarflot, Morten; Arthursson, Astvaldur J.; Søreide, Kjetil (Peer reviewed; Journal article, 2013)
      Background and purpose: Guidelines for fracture treatment and evaluation require a valid classification. Classifications especially designed for children are available, but they might lead to reduced accuracy, considering ...

    • Reliable FASP-based procedures for optimal quantitative proteomic and phosphoproteomic analysis on samples from acute myeloid leukemia patients 

      Hernandez-Valladares, Maria; Aasebø, Elise; Mjaavatten, Olav; Vaudel, Marc; Bruserud, Øystein; Berven, Frode; Selheim, Frode (Peer reviewed; Journal article, 2016-06-21)
      Background Satisfactory sample preparation for mass spectrometry-based analysis is a critical step in the proteomics workflow. The quality and reproducibility of sample preparation can determine the coverage and confidence ...

    • REM sleep behavior disorder is not associated with a more rapid cognitive decline in mild dementia 

      Chwiszczuk, Luiza; Breitve, Monica Haraldseid; Brønnick, Kolbjørn Selvåg; Gjerstad, Michaela D; Hynninen, Kia Minna; Aarsland, Dag; Rongve, Arvid (Peer reviewed; Journal article, 2017-08-07)
      Objectives: REM sleep behavior disorder (RBD) is associated with cognitive dysfunctions and is a risk factor for development of mild cognitive impairment and dementia. However, it is unknown whether RBD is associated with ...

    • Remaining challenges in Tanzania’s efforts to eliminate iodine deficiency 

      Assey, Vincent Didas; Mgoba, Celestin; Mlingi, Nicholaus; Sanga, Alfred; Ndossi, Godwin D.; Greiner, Ted; Peterson, Stefan (Peer reviewed; Journal article, 2007)
      Objective: To determine iodine levels in salt and iodine deficiency prevalence in school-aged children in 16 districts in Tanzania with previous severe iodine deficiency. Design: A cross-sectional study in schoolchildren. ...

    • Remifentanil as analgesia for labour pain 

      Tveit, Tor Oddbjørn (Doctoral thesis, 2013-04-18)
      Aims: To collect updated information about pharmacological labour analgesia in Norway, especially systemic opioids and epidural. Evaluation of efficacy and safety with remifentanil IVPCA (intravenous patient-controlled ...

    • Remote magnetic versus manual catheters: evaluation of ablation effect in atrial fibrillation by myocardial marker levels 

      Solheim, Eivind; Off, Morten Kristian; Hoff, Per Ivar; De Bortoli, Alessandro; Schuster, Peter; Ohm, Ole-Jørgen; Chen, Jian (Peer reviewed; Journal article, 2011-04-08)
      Background A remote magnetic navigation (MN) system is available for radiofrequency ablation of atrial fibrillation (AF), challenging the conventional manual ablation technique. The myocardial markers were measured to ...

    • Remote postconditioning by humoral factors in effluent from ischemic preconditioned rat hearts is mediated via PI3K/Akt-dependent cell-survival signaling at reperfusion 

      Breivik, Lars Ertesvåg; Helgeland, Erik; Aarnes, Eva-Katrine; Mrdalj, Jelena; Jonassen, Anne Kristin (Peer reviewed; Journal article, 2010-12-29)
      Short non-lethal ischemic episodes administered to hearts prior to (ischemic preconditioning, IPC) or directly after (ischemic postconditioning, IPost) ischemic events facilitate myocardial protection. Transferring coronary ...

    • Removal of dental amalgam restorations in patients with health complaints attributed to amalgam: A prospective cohort study 

      Björkman, Lars; Musial, Frauke; Alræk, Terje; Werner, Erik Lønnmark; Weidenhammer, Wolfgang; Hamre, Harald Johan (Journal article; Peer reviewed, 2020)
      Background The Norwegian Ministry of Health and Care Services initiated a project including experimental treatment for patients with health complaints attributed to amalgam restorations. Objective The aim was to ...

    • Renal function, sex and age influence purines and pyrimidines in urine and could lead to diagnostic misinterpretation 

      Salvador, Cathrin Lytomt; Flemmen, Per Tryggve Kjelland; Tøndel, Camilla; Bliksrud, Yngve Thomas; Tsui, Ellen Fun Fong; Brun, Atle; Bjerre, Anna Kristina; Mørkrid, Lars (Journal article; Peer reviewed, 2023)
      Glomerular filtration rate (GFR) is commonly used in clinical practice for the diagnosis and follow-up of chronic kidney disease. Screening for inborn errors of metabolism (IEM) is based on analysis of biomarkers in urine, ...

    • Renal Functional Response-Association With Birth Weight and Kidney Volume 

      Lillås, Bjørn Steinar Demma; Tøndel, Camilla; Melsom, Toralf; Eriksen, Bjørn Odvar; Marti, Hans Peter; Vikse, Bjørn Egil (Journal article; Peer reviewed, 2023)
      Introduction: Renal functional response (RFR) is the acute increase in glomerular filtration rate (GFR) after a protein load. Low RFR is a marker of single nephron hyperfiltration. Low birth weight (LBW) is associated with ...

    • Repeated acetylcholine receptor antibody-concentrations and association to clinical myasthenia gravis development 

      Heldal, Anne Taraldsen; Eide, Geir Egil; Romi, Fredrik Robert; Owe, Jone Furulund; Gilhus, Nils Erik (Peer reviewed; Journal article, 2014-12-02)
      Introduction: We aimed to examine the longitudinal association between Myasthenia Gravis (MG) clinical severity and concentration of acetylcholine receptor (AChR)-antibodies to evaluate if AChR-antibody variations correlate ...

    • Repeated bronchoscopy in health and obstructive lung disease: is the airway microbiome stable? 

      Nielsen, Rune; Xue, Yaxin; Jonassen, Inge; Haaland, Ingvild; Kommedal, Øyvind; Wiker, Harald Gotten; Drengenes, Christine; Bakke, Per S.; Eagan, Tomas Mikal Lind (Journal article; Peer reviewed, 2021)
      Objective Little is known concerning the stability of the lower airway microbiome. We have compared the microbiota identified by repeated bronchoscopy in healthy subjects and patients with ostructive lung diseaseases ...

    • Repeated dispensing of codeine is associated with high consumption of benzodiazepines 

      Bachs, Liliana Casulleras; Bramness, Jørgen G.; Engeland, Anders; Skurtveit, Svetlana (Peer reviewed; Journal article, 2008)
      Aims: Our objective was to explore the use of codeine analgesics in individual patients in Norway, giving special attention to the 10% who consume the highest amounts. Methods: We retrieved data from the Norwegian Prescription ...

    • Repeated Influenza Vaccination Boosts and Maintains H1N1pdm09 Neuraminidase Antibody Titers 

      Hansen, Lena; Zhou, Fan; Amdam, Håkon; Trieu, Mai Chi; Cox, Rebecca Jane (Journal article; Peer reviewed, 2021)
      Antibodies to influenza surface protein neuraminidase (NA) have been found to reduce disease severity and may be an independent correlate of protection. Despite this, current influenza vaccines have no regulatory requirements ...

    • Reperfusion Therapy with Low-Dose Insulin or Insulin-Like Growth Factor 2; Myocardial Function and Infarct Size in a Porcine Model of Ischaemia and Reperfusion 

      Salminen, Pirjo-Riitta; Dahle, Geir Olav; Moen, Christian Arvei; Wergeland, Anita; Jonassen, Anne Kristin; Haaverstad, Rune; Matre, Knut; Grong, Ketil (Peer reviewed; Journal article, 2014-05-19)
      In an open-chest porcine model, we examined whether myocardial pharmacological conditioning at the time of reperfusion with low-dose insulin or insulin-like growth factor 2 (IGF2), not affecting serum glucose levels, could ...

    • Repetitive use of levosimendan for treatment of chronic advanced heart failure: Clinical evidence, practical considerations, and perspectives: An expert panel consensus 

      Nieminen, Markku Sakari; Altenberger, Johann; Ben-Gal, Tuvia; Böhmer, Armin; Comin-Colet, Josep; Dickstein, Kenneth; Édes, István Ferenc; Fedele, Francesco; Fonseca, Cândida; García-González, Martín J.; Giannakoulas, Georgios A.; Iakobishvili, Zaza; Jääskeläinen, Pertti; Karavidas, Apostolos I.; Kettner, Jiří; Kivikko, Matti; Lund, Lars H.; Matskeplishvili, Simon T.; Metra, Marco; Morandi, Fabrizio; Oliva, Fabrízio A.; Parkhomenko, Alexander; Parissis, John T.; Pollesello, Piero; Pölzl, Gerhard; Schwinger, Robert H.G.; Segovia, Javier; Seidel, Monika; Vrtovec, Bojan; Wikström, Gerhard (Peer reviewed; Journal article, 2014-06-15)
      Background The intravenous inodilator levosimendan was developed for the treatment of patients with acutely decompensated heart failure. In the last decade scientific and clinical interest has arisen for its repetitive or ...

    • Replication and cross-validation of type 2 diabetes subtypes based on clinical variables: an IMI-RHAPSODY study 

      Slieker, Roderick C.; Donnelly, Louise A.; Fitipaldi, Hugo; Bouland, Gerard A.; Giordano, Giuseppe N.; Åkerlund, Mikael; Gerl, Mathias J.; Ahlqvist, Emma; Ali, Ashfaq; Dragan, Iulian; Festa, Andreas; Hansen, Michael K.; Mansour Aly, Dina; Kim, Min; Kuznetsov, Dmitry; Mehl, Florence; Klose, Christian; Simons, Kai; Pavo, Imre; Pullen, Timothy J.; Suvitaival, Tommi; Wretlind, Asger; Rossing, Peter; Lyssenko, Valeriya; Legido-Quigley, Cristina; Groop, L; Thorens, Bernard; Franks, Paul W; Ibberson, Mark; Rutter, Guy A.; Beulens, Joline W.J.; ‘t Hart, Leen M.; Pearson, Ewan R. (Journal article; Peer reviewed, 2021)
      Aims/hypothesis: Five clusters based on clinical characteristics have been suggested as diabetes subtypes: one autoimmune and four subtypes of type 2 diabetes. In the current study we replicate and cross-validate these ...

    • Replication protein A prevents accumulation of single-stranded telomeric DNA in cells that use alternative lengthening of telomeres 

      Grudic, Amra; Jul-Larsen, Åsne; Haring, SJ; Wold, MS; Lønning, Per Eystein; Bjerkvig, Rolf; Bøe, Stig Ove (Peer reviewed; Journal article, 2007-10-24)
      The activation of a telomere maintenance mechanism is required for cancer development in humans. While most tumors achieve this by expressing the enzyme telomerase, a fraction (5–15%) employs a recombination-based mechanism ...

    • Reporting of health equity considerations in cluster and individually randomized trials 

      Jull, Janet; Yoganathan, Manosila; Dewidar, Omar; Baird, Sarah; Grimshaw, Jeremy M.; Johansson, Kjell Arne; Kristjansson, Elizabeth; McGowan, Jesse; Moher, David; Petticrew, Mark; Robberstad, Bjarne; Shea, Beverly; Tugwell, Peter; Volmink, Jimmy; Wells, George A.; Whitehead, Margaret; Cuervo, Luis Gabriel; White, Howard; Taljaard, Monica; Welch, Vivian; Petkovic, Jennifer (Journal article; Peer reviewed, 2020)
      Background The randomized controlled trial (RCT) is considered the gold standard study design to inform decisions about the effectiveness of interventions. However, a common limitation is inadequate reporting of the ...

    • Repositioning of the global epicentre of non-optimal cholesterol 

      Taddei, Cristina; Zhou, Bin; Bixby, Honor; Carrillo-Larco, Rodrigo M.; Danaei, Goodarz; Jackson, Rod T.; Ahmed, Soheir H; Andersen, Lars Bo; Anderssen, Sigmund Alfred; Ariansen, Inger Kristine Holtermann; Bjertness, Espen; Bjertness, Marius Bergsmark; Graff-Iversen, Sidsel; Haugsgjerd, Teresa Risan; Janszky, Imre; Krokstad, Steinar; Laugsand, Lars Erik; Madar, Ahmed Ali; Mathiesen, Ellisiv B.; Meyer, Haakon E; Sen, Abhijit; Tell, Grete S.; Vatten, Lars Johan; Wilsgaard, Tom; Farzadfar, Farshad; Sophiea, Marisa K.; Di Cesare, Mariachiara; Iurilli, Maria L. C.; Martinez, Andrea Rodriguez; Asghari, Golaleh; Dhana, Klodian; Gulayin, Pablo; Kakarmath, Sujay; Santero, Marilina; Voortman, Trudy; Riley, Leanne M.; Cowan, Melanie J.; Savin, Stefan; Bennett, James E.; Stevens, Gretchen A.; Paciorek, Christopher J.; Aekplakorn, Wichai; Cifkova, Renata; Giampaoli, Simona; Kengne, Andre Pascal; Khang, Young-Ho; Kuulasmaa, Kari; Laxmaiah, Avula; Margozzini, Paula; Mathur, Prashant (Journal article; Peer reviewed, 2020-06)
      High blood cholesterol is typically considered a feature of wealthy western countries1,2. However, dietary and behavioural determinants of blood cholesterol are changing rapidly throughout the world3 and countries are using ...