Browsing Faculty of Medicine by Title
Now showing items 3794-3813 of 8826
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High birth weight and perinatal mortality among siblings. A register based study in Norway, 1967-2011
(Peer reviewed; Journal article, 2017-02-28)Background: Perinatal mortality according to birth weight has an inverse J-pattern. Our aim was to estimate the influence of familial factors on this pattern, applying a cohort sibling design. We focused on excess mortality ... -
High BMI is significantly associated with positive progesterone receptor status and clinico-pathological markers for non-aggressive disease in endometrial cancer
(Peer reviewed; Journal article, 2011)Background: Endometrial cancer incidence is increasing in industrialised countries. High body mass index (BMI, kg m−2) is associated with higher risk for disease. We wanted to investigate if BMI is related to clinico-pathological ... -
The high burden of infant deaths in rural Burkina Faso: a prospective community-based cohort study
(Peer reviewed; Journal article, 2012-09-05)Background: Infant mortality rates (IMR) remain high in many sub-Saharan African countries, especially in rural settings where access to health services may be limited. Studies in such communities can provide relevant data ... -
High cardiac background activity limits 99mTc-MIBI radioguided surgery in aortopulmonary window parathyroid adenomas
(Peer reviewed; Journal article, 2014-04-23)Background: Radioguided surgery using 99m-Technetium-methoxyisobutylisonitrile (99mTc-MIBI) has been recommended for the surgical treatment of mediastinal parathyroid adenomas. However, high myocardial 99mTc-MIBI uptake ... -
High circulating levels of the homeostatic chemokines CCL19 and CCL21 predict mortality and disease severity in Covid-19
(Journal article; Peer reviewed, 2022)Background Immune dysregulation is a major factor in the development of severe coronavirus disease 2019 (COVID-19). The homeostatic chemokines CCL19 and CCL21 have been implicated as mediators of tissue inflammation, but ... -
A high confidence, manually validated human blood plasma protein reference set
(Peer reviewed; Journal article, 2008-09-15)Background: The immense diagnostic potential of human plasma has prompted great interest and effort in cataloging its contents, exemplified by the Human Proteome Organization (HUPO) Plasma Proteome Project (PPP) pilot ... -
High Constitutive Cytokine Release by Primary Human Acute Myeloid Leukemia Cells Is Associated with a Specific Intercellular Communication Phenotype
(Peer reviewed; Journal article, 2019-07-04)Acute myeloid leukemia (AML) is a heterogeneous disease, and this heterogeneity includes the capacity of constitutive release of extracellular soluble mediators by AML cells. We investigated whether this capacity is ... -
High degree of heterogeneity of PD-L1 and PD-1 from primary to metastatic endometrial cancer
(Journal article; Peer reviewed, 2020)Objective PD-L1 and PD-1 are predictive markers for immunotherapy and increasingly relevant in endometrial cancer. The reported fraction of positive primary tumors has been inconsistent. We investigated the expression of ... -
High expression of miR‑17‑5p in tumor epithelium is a predictor for poor prognosis for prostate cancer patients
(Journal article; Peer reviewed, 2021)MicroRNAs (miRs) are small non-coding RNA molecules, which are involved in the development of various malignancies, including prostate cancer (PCa). miR-17-5p is considered the most prominent member of the miR-17-92 cluster, ... -
High failure rate after internal fixation and beneficial outcome after arthroplasty in treatment of displaced femoral neck fractures in patients between 55 and 70 years. An observational study of 2,713 patients reported to the Norwegian Hip Fracture Register
(Peer reviewed; Journal article, 2018)Background and purpose — The treatment of patients between 55 and 70 years with displaced intracapsular femoral neck fracture remains controversial. We compared internal fixation (IF), bipolar hemiarthroplasty (HA) and ... -
High flow nasal cannula in children: A literature review
(Peer reviewed; Journal article, 2016-07-12)High flow nasal cannula (HFNC) is a relatively new non-invasive ventilation therapy that seems to be well tolerated in children. Recently a marked increase in the use of HFNC has been seen both in paediatric and adult care ... -
High incidence and prevalence of MS in Møre and Romsdal County, Norway, 1950–2018
(Journal article; Peer reviewed, 2020)Objective To determine prevalence and longitudinal trends in incidence of MS in Møre and Romsdal County, Western Norway, from 1950 to 2018. Methods Retrospective longitudinal population-based observational study. All ... -
High levels of discordant antimicrobial therapy in hospital-acquired bloodstream infections is associated with increased mortality in an intensive care, low antimicrobial resistance setting
(Journal article; Peer reviewed, 2022)Background Bloodstream infections (BSI) occur frequently and are associated with severe outcomes. In this study we aimed to investigate proportions of patients that received discordant empirical antimicrobial therapy and ... -
High maternal mortality estimated by the sisterhood method in a rural area of Mali
(Peer reviewed; Journal article, 2011-08-03)Background: Maternal mortality is high in Mali. Nevertheless, there are few studies on this topic from rural areas, and current estimates are mostly based on studies from urban settings. Our objective was to estimate the ... -
High maternal mortality in a rural south-west Ethiopia: estimate by using the sisterhood method
(Peer reviewed; Journal article, 2012-11-23)Background: Estimation of maternal mortality is difficult in developing countries without complete vital registration. The indirect sisterhood method represents an alternative in places where there is high fertility and ... -
High mobility group box 1 and a network of other biomolecules influence fatigue in patients with Crohn’s disease
(Journal article; Peer reviewed, 2023)Background Fatigue is common in patients with chronic inflammatory and autoimmune diseases, often with a severe impact on the patient’s daily life. From a biological point of view, fatigue can be regarded as an element ... -
High mortality due to cutaneous melanoma in norway: A study of prognostic factors in a nationwide cancer registry
(Peer reviewed; Journal article, 2018-05-09)Purpose: The purpose of this study was to examine why Norway has the highest rate of mortality due to cutaneous melanoma (CM) in Europe. The Norwegian Malignant Melanoma Registry (NMMR) enables the study of clinical and ... -
High neopterin and IP-10 levels in cerebrospinal fluid are associated with neurotoxic tryptophan metabolites in acute central nervous system infections
(Peer reviewed; Journal article, 2018-11-23)Background The host response to intruders in the central nervous system (CNS) may be beneficial but could also be harmful and responsible for neurologic symptoms and sequelae in CNS infections. This immune response induces ... -
High Norwegian prostate cancer mortality: evidence of over-reporting
(Peer reviewed; Journal article, 2018)Objective: This study aimed to determine the level of misattribution of prostate cancer deaths in Norway based on the county of Vestfold in the years 2009–2014. Materials and methods: The study included 328 patients ... -
High number of hypoglycaemic episodes identified by CGM among home-dwelling older people with diabetes: an observational study in Norway
(Journal article; Peer reviewed, 2023)Background A scoping review from 2021 identified a lack of studies on the incidence, prevention and management of hypoglycaemia in home-dwelling older people with diabetes. The aim of this study was to investigate the ...