Browsing Faculty of Medicine by Title
Now showing items 3891-3910 of 9108
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HER2, Tissue Factor, TROP2 and NECTIN4 as targets for antibody-drug conjugate (ADC) therapy in cervical cancer
(Master thesis, 2024-06-03)Early-stage cervical cancers are generally associated with good prognosis. However, for late stage or recurrent disease, survival rates drop significantly, with limited treatment options available. Antibody drug conjugates ... -
Herbal medicine use among pregnant women attending antenatal clinics in Lusaka Province, Zambia: a cross-sectional, multicentre study
(Master thesis, 2020-06-26)Background: We aimed to determine the prevalence and patterns of herbal medicine (HM) use during pregnancy in Lusaka Province, Zambia. Methods: A survey-based, cross-sectional, multicentre study was conducted in 446 adult ... -
Herbal medicine use among pregnant women attending antenatal clinics in Lusaka Province, Zambia: A cross-sectional, multicentre study
(Journal article; Peer reviewed, 2020)Background and purpose: The study of herbal medicine (HM) use which is related to maternal health, a public health priority in many sub-Saharan African countries including Zambia, has been limited. Accordingly, we aimed ... -
Herbal Medicine Use During Pregnancy: A Review of the Literature With a Special Focus on Sub-Saharan Africa
(Journal article; Peer reviewed, 2020-06-09)Herbal medicine use has grown considerably worldwide among pregnant women, and is particularly widespread in sub-Saharan Africa. However, herbal medicines used across sub-Saharan Africa are associated with important research ... -
Herbal plants used in traditional Chinese medicine as a source of compounds with potential medical utilities - identification, characterization and organization
(Master thesis, 2010-05-19)The history and knowledge of Chinese herbal medicine is over 3000 years old, and over 10 000 herbs are recorded and are in use for different conditions. This is an enormous amount of knowledge that can be used to find new ... -
Hereditary Colorectal Cancer
(Doctoral thesis, 2007-04-13) -
Hereditary hypophosphatemia in Norway: A retrospective population-based study of genotypes, phenotypes, and treatment complications
(Peer reviewed; Journal article, 2016-02)Objective: Hereditary hypophosphatemias (HH) are rare monogenic conditions characterized by decreased renal tubular phosphate reabsorption. The aim of this study was to explore the prevalence, genotypes, phenotypic spectrum, ... -
Hereditary phosphate balance disorders in Norwegian children
(Doctoral thesis, 2016-05-03)Background: Hereditary hypophosphatemia (HH) is a group of diseases characterized by monogenic hypophosphatemia due to reduced tubular maximum reabsorption of phosphate per glomerular filtration rate (TmP/GFR). This group ... -
Hereditary renal disease in the Norwegian population, with a focus on Fabry disease
(Doctoral thesis, 2017-10-13)Background: Clinical experience and studies suggest that end stage renal disease (ESRD) without known Mendelian origins may aggregate in families, and increased risk of death has been reported in relatives of patients with ... -
Herpes Simplex Virus Type 1 Neuronal Infection Triggers the Disassembly of Key Structural Components of Dendritic Spines
(Journal article; Peer reviewed, 2021)Herpes simplex virus type 1 (HSV-1) is a widespread neurotropic virus. Primary infection of HSV-1 in facial epithelium leads to retrograde axonal transport to the central nervous system (CNS) where it establishes latency. ... -
Herpesviral interactomics. Intraviral and virus-host protein-protein interaction network from different species of herpesviruses
(Doctoral thesis, 2008-02-01) -
Herring roe oil in treatment of psoriasis – influence on immune cells and cytokine network
(Journal article; Peer reviewed, 2023)Background: Psoriasis is a chronic immune-mediated skin disease with systemic inflammation and comorbidities. Although the disease severity may vary over time, many patients suffer from mild to moderate disease. Often local ... -
Heterogeneity in the risk of cardiovascular disease mortality after the hypertensive disorders of pregnancy across mothers' lifetime reproductive history
(Journal article; Peer reviewed, 2024)Background Prior studies on maternal cardiovascular disease (CVD) mortality and hypertensive disorders of pregnancy (HDP) have focused only on a woman's first birth and have not accounted for successive affected ... -
Heterogeneity of patient-derived acute myeloid leukemia cells subjected to SYK in vitro inhibition
(Journal article; Peer reviewed, 2022)Acute myeloid leukemia (AML) is an aggressive hematological malignancy with a dismal prognosis. The cytoplasmic spleen tyrosine kinase (SYK) is highly expressed by hematopoietic cells and has emerged as a potential therapeutic ... -
Heterogeneous contributions of change in population distribution of body mass index to change in obesity and underweight
(Journal article; Peer reviewed, 2021)From 1985 to 2016, the prevalence of underweight decreased, and that of obesity and severe obesity increased, in most regions, with significant variation in the magnitude of these changes across regions. We investigated ... -
Hfe genotype, ferritin levels and transferrin saturation in patients with suspected hereditary hemochromatosis
(Journal article; Peer reviewed, 2021)HFE hemochromatosis is characterized by increased iron absorption and iron overload due to variants of the iron-regulating HFE gene. Overt disease is mainly associated with homozygosity for the C282Y variant, although the ... -
HIDEA syndrome is caused by biallelic, pathogenic, rare or founder P4HTM variants impacting the active site or the overall stability of the P4H-TM protein
(Journal article; Peer reviewed, 2022)HIDEA syndrome is caused by biallelic pathogenic variants in P4HTM. The phenotype is characterized by muscular and central hypotonia, hypoventilation including obstructive and central sleep apneas, intellectual disability, ... -
A hierarchical frailty model applied to two-generation melanoma data
(Peer reviewed; Journal article, 2010)We present a hierarchical frailty model based on distributions derived from non-negative Lévy processes. The model may be applied to data with several levels of dependence, such as family data or other general clusters, ... -
High accuracy mass spectrometry analysis as a tool to verify and improve gene annotation using Mycobacterium tuberculosis as an example
(Peer reviewed; Journal article, 2008-07-02)Background: While the genomic annotations of diverse lineages of the Mycobacterium tuberculosis complex are available, divergences between gene prediction methods are still a challenge for unbiased protein dataset generation. ... -
High attrition among HIV-infected patients with advanced disease treated in an intermediary referral center in Maputo, Mozambique
(Peer reviewed; Journal article, 2014-04-08)Background: In Mozambique, antiretroviral therapy (ART) scale-up has been successfully implemented. However, attrition in care remains a major programmatic challenge. In 2009, an intermediary-level HIV referral center was ...