Browsing Faculty of Medicine by Title
Now showing items 4555-4574 of 8845
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Integrating protein structural dynamics and evolutionary analysis with Bio3D
(Peer reviewed; Journal article, 2014-12-10)Background: Popular bioinformatics approaches for studying protein functional dynamics include comparisons of crystallographic structures, molecular dynamics simulations and normal mode analysis. However, determining how ... -
Integration of ear and hearing care into primary health care in Malawi with special reference to task-sharing.
(Doctoral thesis, 2020-04-29)Introduction: The prevalence of hearing impairment has increased rapidly over the last two decades. The burden is higher in Africa and South East Asia than in richer parts of the world. The majority of this hearing impairment ... -
Integration of smoking cessation into standard treatment for patients receiving opioid agonist therapy who are smoking tobacco: protocol for a randomised controlled trial (ATLAS4LAR)
(Journal article; Peer reviewed, 2022)Background About 85% of patients receiving opioid agonist therapy (OAT) for opioid dependence are smoking tobacco. Although smoke-related pulmonary diseases are significant contributors to morbidity and mortality, few ... -
Integration of tuberculosis services in Taiwan, 2001: challenges and opportunities
(Doctoral thesis, 2012-10-02) -
Integrin a11 is overexpressed by tumour stroma of head and neck squamous cell carcinoma and correlates positively with alpha smooth muscle actin expression
(Peer reviewed; Journal article, 2017-04)BACKGROUND: Cancer-associated fibroblasts (CAFs) were shown to be important for tumour progression in head and neck squamous cell carcinomas (HNSCCs). Their heterogeneity and lack of specific markers is increasingly ... -
Integrin Binding Dynamics Modulate Ligand-Specific Mechanosensing in Mammary Gland Fibroblasts
(Journal article; Peer reviewed, 2020)The link between integrin activity regulation and cellular mechanosensing of tissue rigidity, especially on different extracellular matrix ligands, remains poorly understood. Here, we find that primary mouse mammary gland ... -
Integrin α11 cytoplasmic tail is required for FAK activation to initiate 3D cell invasion and ERK-mediated cell proliferation
(Peer reviewed; Journal article, 2019)Integrin α11β1 is a collagen-binding integrin, which is receiving increasing attention in the context of wound healing and fibrosis. Although α11β1 integrin displays similar collagen specificity to α2β1 integrin, both ... -
Integrin α11β1 in tumor fibrosis: more than just another cancer-associated fibroblast biomarker?
(Journal article; Peer reviewed, 2022)There is currently an increased interest in understanding the role of the tumor microenvironment (TME) in tumor growth and progression. In this context the role of integrins in cancer-associated fibroblasts (CAFs) will ... -
Integrin α11β1 is a receptor for collagen XIII
(Journal article; Peer reviewed, 2021)Collagen XIII is a conserved transmembrane collagen mainly expressed in mesenchymal tissues. Previously, we have shown that collagen XIII modulates tissue development and homeostasis. Integrins are a family of receptors ... -
Integrin α11β1 is expressed in breast cancer stroma and associates with aggressive tumor phenotypes
(Peer reviewed; Journal article, 2020)Cancer‐associated fibroblasts are essential modifiers of the tumor microenvironment. The collagen‐binding integrin α11β1 has been proposed to be upregulated in a pro‐tumorigenic subtype of cancer‐associated fibroblasts. ... -
Intense pulsed light treatment in meibomian gland dysfunction: Past, present, and future
(Journal article; Peer reviewed, 2023)Dry eye disease is a highly prevalent condition, which can substantially impair quality of life, work productivity, and vision. It is considered an inflammatory disease and the most common cause is meibomian gland dysfunction. ... -
Intensified follow-up of patients with type 1 diabetes and poor glycaemic control: A multicentre quality improvement collaborative based on data from the Norwegian Diabetes Register for Adults
(Journal article; Peer reviewed, 2023)Background Patients with type 1 diabetes mellitus (T1DM) and poor glycaemic control are at high risk of developing microvascular and macrovascular complications. The aim of this study was to determine if a quality improvement ... -
Intensity-modulated radiotherapy of pelvic lymph nodes in locally advanced prostate cancer: planning procedures and early experiences
(Peer reviewed; Journal article, 2008-07-15) -
Intensive chemotherapy for acute myeloid leukemia differentially affects circulating TC1, TH1, TH17 and TREG cells
(Peer reviewed; Journal article, 2010-07-09)Background Several observations suggest that immunological events early after chemotherapy, possibly during the period of severe treatment-induced cytopenia, are important for antileukemic immune reactivity in acute myeloid ... -
Intensive Group Training in a Local Community Setting for Children with Cerebral Palsy. Methodological Aspects and Change in Motor Functioning
(Doctoral thesis, 2010-02-18)The purpose of this thesis was to examine measurement properties of three outcome measures of motor function for children with cerebral palsy (CP), and to investigate change in their motor functioning following three weeks ... -
Intensive-phase treatment outcomes among hospitalized multidrug-resistant tuberculosis patients: Results from a nationwide cohort in Nigeria
(Peer reviewed; Journal article, 2014-04-10)Background: Nigeria is faced with a high burden of Human Immunodeficiency Virus (HIV) infection and multidrug-resistant tuberculosis (MDR-TB). Treatment outcomes among MDR-TB patients registered across the globe have been ... -
Inter-hospital transfer: the crux of the trauma system, a curse for trauma registries
(Journal article, 2010-03-16)The inter-hospital transfer of patients is crucial to a well functioning trauma system, and the transfer process may serve as a quality indicator for regional trauma care. However, the assessment of the transfer process ... -
Inter-tester reliabilitet på screening av danserne ved Nasjonalballetten i Norge - En tverrsnittstudie
(Master thesis, 2014-11-12)Objective Dancers are highly prone to injuries. Little research has been done on dancers compared to other athletes, and the few studies done often have poor quality. Screening of athletes was introduced to assess risk ... -
Interaction between gas cooking and GSTM1 null genotype in bronchial responsiveness: Results from the European Community Respiratory Health Survey
(Peer reviewed; Journal article, 2014)Background: Increased bronchial responsiveness is characteristic of asthma. Gas cooking, which is a major indoor source of the highly oxidant nitrogen dioxide, has been associated with respiratory symptoms and reduced lung ...